HIV/AIDS and Nutrition: A Patient Educational Guide
Pathophysiology of HIV/AIDS
HIV “(Human Immunodeficiency Virus)” attacks the body's defense mechanisms, particularly
the CD4 cells, better known as T-helper cells, which are responsible for fighting off an infection
(Siahaan et al., 2024). It is transmitted via blood, breast milk, semen, and vaginal fluids. It can be
passed through unprotected sex, blood transfusions, sharing needles, or from mother to child.
The HIV infection, over time, leads to the destruction of CD4 cells, resulting in the weakening of
the immune system and the full-blown disease of AIDS “(Acquired Immunodeficiency
Syndrome)”.
“If left untreated, HIV weakens the body's ability to fight opportunistic infections and certain
types of cancers.”
Symptoms
Persistent fever and night sweats.
Chronic fatigue and weight loss.
Swollen lymph nodes.
Recurrent infections or illnesses.
Medications and Nutritional Considerations
1. Dolutegravir (Tivicay)
Mechanism of Action: “Inhibits integrase enzyme, preventing HIV DNA from integrating
into the host genome.”
Nutritional Considerations:
Take with or without food.
Avoid high-calcium or high-iron foods (e.g., dairy, spinach) close to medication time;
they can reduce absorption.
Ensure a balanced diet to support immune health.
2. “Emtricitabine/Tenofovir (Truvada)- Inhibits reverse transcriptase, preventing HIV
replication.”
Take with a meal to minimize gastrointestinal side effects.
Maintain adequate hydration.
Avoid alcohol, as it can exacerbate liver stress.
Evidence-Based Diet for HIV/AIDS
High-Protein Diet
A high-protein diet helps combat muscle wasting, a common issue in HIV patients, and
supports immune health.
Three Foods to Include
Lean meats (chicken, turkey): Rich in protein, supports muscle repair and immune
function.
Beans and lentils: High in protein and fiber, supports gut health.
Eggs: Provide high-quality protein and essential nutrients like B vitamins.
Three Foods to Avoid
Processed foods (chips, sugary snacks): Increase inflammation and provide low
nutritional value.
“Raw or undercooked eggs, meat, and seafood: Increase the risk of foodborne illnesses
due to weakened immunity.”
Excess alcohol: Impairs liver function and interacts negatively with medications.
Patient Resources
On Evidence-Based Diets
Academy of Nutrition and Dietetics: [Link]
On HIV/AIDS
Centers for Disease Control and Prevention (CDC): [Link]/hiv