INTRODUCTION TO TABLET
PRESENTED BY – OM RAGHUVANSHI
. T .B PHAM
GUIDANCE BY – MR .KETAN PATIL SIR
DEFINITION OF TABLET
Tablet is defined as a compressed solid dosage form containing medicaments with or
without excipients
According to the Indian Pharmacopoeia Pharmaceutical tablets are solid, flat or biconvex
dishes, unit dosage form, prepared by compressing a drugs or a mixture of drugs, with or
without diluents. They vary in shape and differ greatly in size and weight, depending on
amount of medicinal substances and the intended mode of administration.
It is the most popular dosage form and 70% of the total medicines are dispensed in the
form of Tablet. All medicaments are available in the Tablet form except where it is difficult
to formulate or administer
IDEAL CHARECTERISTICS OF TABLET:
A tablet should have elegant product identity while free of defects like chips, cracks,
discoloration, and contamination.
Should have sufficient strength to withstand mechanical shock during its productiopn
packaging, shipping and dispensing
Should have the chemical and physical stability to maintain its physical attributes over
time l
The tablet must be able to release the medicinal agents in a predictable and reproducible
manner
Must have a chemical stability over time so as not to follow alteration of the medicinal agent
ADVANTAGES
• An accurate amount of medicament, even if very small, can be incorporated.
• Tablets provide best combined properties of chemical, mechanical and microbiological
stability of all the oral dosage forms.
• Since they are generally produced on a large scale, therefore, their cost of production
is relatively low, hence economical.
• They are in general the easiest and cheapest to package and ship among all oral dosage
forms.
• Some specialized tablets may be prepared for modified release profile of the drug.
• Product identification is potentially the simplest and cheapest requiring no adl
• They are easy to carry, easy to swallow and they are attractive in
appearance.
• • Unpleasant taste can be masked by sugar coating .
DISADVANTAGE
• Difficult to swallow in case of children and unconscious patients.
• Drugs with poor wetting, slow dissolution properties, optimum absorption high in GIT
may be difficult to formulate or manufacture as a tablet that will still provide
adequate or full drug bioavailability.
• Bitter testing drugs, drugs with an objectionable odor or drugs that are sensitive to
• oxygen may require encapsulation or coating. In such cases, capsule may offer the
best
• and lowest cost.
TYPES OF TABLETS (CLASSIFICATION)
• A. Tablets ingested orally:
• Compressed tablet, e.g. Paracetamol tablet
• Multiple compressed tablet
• Repeat action tablet
• Delayed release tablet, e.g. Enteric coated Bisacodyl tablet
• Sugar coated tablet, e.g. Multivitamin table
• Film coated tablet, e.g. Metronidazole tablet
• B. Tablets used in oral cavity:
• Buccal tablet, e.g. Vitamin‐ c tablet
• Sublingual tablet, e.g. Vicks Menthol tablet
• Troches or lozenges 4. Dental cone
• C. Tablets administered by other route:
• Implantation tablet
• Vaginal tablet, e.g. Clotrimazole tablet
• D. Tablets used to prepare solution:
• Effervescent tablet, e.g. Dispirin tablet (Aspirin)
• Dispensing tablet, e.g. Enzyme tablet (Digiplex)
• Hypodermic tablet
• Tablet triturates e.g. Enzyme tablet (Digiplex)