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MPH201T 2023

This document outlines the examination details for the M.Pharm Semester-2 course at Gujarat Technological University, specifically for the subject of Molecular Pharmaceutics. It includes instructions for the exam, a list of questions covering various topics such as Immunoliposomes, Nanoparticles, targeting delivery systems, and gene therapy. The exam is scheduled for August 4, 2023, with a total of 80 marks available.

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Sahil Patel
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187 views1 page

MPH201T 2023

This document outlines the examination details for the M.Pharm Semester-2 course at Gujarat Technological University, specifically for the subject of Molecular Pharmaceutics. It includes instructions for the exam, a list of questions covering various topics such as Immunoliposomes, Nanoparticles, targeting delivery systems, and gene therapy. The exam is scheduled for August 4, 2023, with a total of 80 marks available.

Uploaded by

Sahil Patel
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Seat No.: _____ Enrolment No.

_____________

GUJARAT TECHNOLOGICAL UNIVERSITY


[Link] - SEMESTER–2 EXAMINATION – SUMMER -2023

Subject Code: MPH201T Date: 04-08-2023


Subject Name: Molecular Pharmaceutics(Nano Tech and Targeted DDS)
Time: 10:30AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define Immunoliposome. Explain the thin film hydration technique with 06
various parameters to be optimized.
(b) Write a note on Proliposomes with their advantages and disadvantages. 05
(c) Discuss the role of Liposomes in gene delivery. 05
Q.2 (a) Enlist various methods of preparing Nanoparticles. Explain any one in detail. 06
(b) Explain the applications of Nanoparticles in targeting delivery systems. 05
(c) Discuss the quality control tests or evaluation parameters of Nanoparticles. 05
Q.3 (a) Differentiate Active and Passive targeting. Explain active targeting in detail. 06
(b) How MoAb can be targeted against breast cancer with anti cancer 05
drug?Explain.
(c) Write a note on recent advances on brain targeting. 05
Q.4 (a) Differentiate between Microspheres and Nanoparticles. Explain any one 06
method of preparing Microspheres.
(b) Discuss the Hybridoma technology of MoAb. 05
(c) Explain the applications of Aquasomes and Phytosomes. 05
Q.5 (a) Explain the factors affecting permeability of nasal mucosa. 06
(b) How particle size plays role in Pulmonary drug delivery? In what way 05
assessment of aerodynamic diameter will influence the same?
(c) Write short notes on types of propellants used in aerosols. 05
Q. 6 (a) Enumerate on Gene Therapy and its applications. 06
(b) Discuss the pharmacokinetic phenomenon in Nucleic acid based therapy. 05
(c) Differentiate Anti sense molecules and Aptamers as drugs in Nucleic acid 05
therapy.
Q.7 (a) Describe the factors affecting drug transport in Blood Brain Barrier. 06
(b) Write short notes on suitability of drugs for Solid Lipid Nanoparticles 05
preparation and method of preparing SLN.
(c) Differentiate Microspheres and Microcapsules. Explain the biodegradable 05
polymers used in Microencapsulation technique.

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