HYALINE CARTILAGE
Covered by perichondrium except articular cartilage
Consists of
o Cell nests or Isogenous groups
o Interstitial & Territorial matrix
Ex : Nasal cartilages, costal cartilages, articular cartilages, Thyroid
cartilage, Tracheal cartilage
ELASTIC CARTILAGE
Covered by perichondrium
Chondrocytes in lacunae
Matrix consists of Elastic fibres stained by verheoff’s stain (Bluish black)
Ex: cartilages of Ear, Auditory tube, Epiglottis
WHITE FIBRO CARTILAGE
No perichondrium
Rows of chondrocytes in Lacunae
Bundles of collagen fibres in Matrix
Ex: Intervertebral discs, Intraarticular discs, Acetabular & Glenoidal
labrum
COMPACT BONE T.S
Consists of osteocytes in lacunae with canaliculi
Haversian canals, Volkmann’s canals transmits blood vessels & nerves
Osteon : Haversian canal surrounded by 5 to 6 concentric lamellae
3 types of lamellae
o Circumferential lamellae
o Concentric lamellae
o Interstitial lamellae
COMPACT BONE L.S
Consists of osteocytes in lacunae with canaliculi
Vertical sections of Haversian canals
Volkmann’s canals connecting Haversian canals seen
SKELETAL MUSCLE
Multinucleated parallel running fibres
Peripherally placed nuclei
Cross striations
Alternate Dark (A-Band) & Light (I-Band)
Sarcolemma(cell membrane), Sarcoplasm(cytoplasm), Sarcoplasmic
Reticulum( Endoplasmic Reticulum)
CARDIAC MUSCLE
Branching & Anastomosing fibres
Centrally placed oval nucleus
Cell junctions are Intercalated discs
Few cross striations within the fibres
Seen in Myocardium of Heart
SMOOTH MUSCLE
Each muscle fibre is Spindle shaped
Centrally placed nucleus
Tapering end of one fibre comes near broad part of another fibre
Seen in the viscera
NERVE T.S OSMIC ACID
Black ring arranged in groups seen( Myelin sheath)
Osmic acid stains myelin sheath imparting black colour
DORSAL ROOT/SPINAL/ SENSORY GANGLION
Surrounded by connective tissue capsule
Groups of large ganglion cells (pseudounipolar) surrounded by Satellite
cells(capsular cells)
Separated by bundles of nerve fibres with nuclei of Schwann cells ,
Neuroglial cells
SYMPATHETIC/ AUTONOMIC GANGLION
Surrounded by connective tissue capsule
Multipolar neurons surrounded by satellite cells
Nerve fibres are scattered in between neurons, schwann cell nuclei
among fibres
MUSCULAR ARTERY
Tunica media is thicker, Lumen is patent, Wall of artery is thicker than
the vein
Tunica intima
o Endothelium
o Subendothelial C.T
o Prominent wavy Internal elastic lamina
Tunica media
o Severs layers of Smooth muscle fibres
o Elastic fibres
o External elastic lamina
Tunica adventitia
o Collagen , elastic fibres
ELASTIC/ LARGE ARTERY
Elastic fibres form the bulk of tunica media
About 50 layers of fenestrated sheets of elastic fibres in tunica media
Tunica adventitia is thinner, consists of vasa vasorum
LARGE VEIN
Wall is thinner, lumen is collapsed, valves are present
Tunica adventitia is thicker than Tunica media with longitudinal
orientation of smooth muscle fibres in adventitia
Internal elastic lamina is not prominent
LYMPH NODE
Covered by capsule
Subcapsular sinus is the identifying feature
Network is formed by reticular fibres
Consists of
o Outer cortex with lymphatic follicles & trabecular sinuses
o Inner medulla with cords of lymphocytes & medullary sinuses
o Paracortex is present in between follicles, between cortex &
medulla
SPLEEN
Covered by capsule
Thick septa or trabeculae
Network is formed by reticular fibres
Consists of
o Red pulp with splenic sinusoids covered by cords of billroth
o White pulp / malpighian corpuscle
Eccentric arteriole surrounded by periarteriolar sheath of
lymphocytes
Penicilli, ellipsoids
THYMUS
Covered by capsule
Network is formed by Epitheloid cells ( cellular)
Thymic lobule with outer dark staining cortex & inner light staining
medulla
Hassall’s/ Thymic corpuscles are pinkish bodies seen in the medulla of
aged thymus
PALATINE TONSIL
Lymphatic nodules covered by stratified squamous non keratinized
epithelium
Capsule covers the palatine tonsil from below
Intra tonsillar crypt or cleft is a remnant if 2nd pharyngeal pouch
THIN SKIN / HAIRY SKIN
Consists of Epidermis & Dermis
Epidermis consists of
o Stratum basale, Stratum spinosum, stratum granulosum, stratum
lucidum, stratum corneum
o Melanocytes are seen in St. basale
Dermis consists of
o Inner reticular layer
o Outer papillary layer
o Sweat glands , sebaceous glands, hair follicle, arrector pilorum
muscle
THICK SKIN
Seen in palms & soles
Stratum lucidum is difficult to see in epidermis
Hair follicles & sebaceous glands are absent
Dermal papillae are prominent in thick skin
TRACHEA
Mucosa
o Pseudostratified ciliated columnar epithelium with goblet cells
o Lamina propria with BALT
Submucosa
o Connective tissue with seromucinous tracheal glands
Hyaline cartilage
Adventitia
o Connective tissue, blood vessels , nerves
LUNG
Outermost covering is pleural serous layer
Intra pulmonary bronchi consists of Pseudostratified ciliated columnar
epithelium with goblet cells, lamina propria, narrow smooth muscle
layer, submucosa with bronchial glands, cartilaginous plates, adventitia
Bronchioles consists of Pseudostratified ciliated columnar epithelium
with occasional goblet cells, mucosal folds due to smooth muscle layer,
no bronchial glands &cartilaginous plates, adventitia
Terminal bronchiole consists of ciliated columnar epithelium, , mucosal
folds due to smooth muscle layer , adventitia, less than 1mm in
diameter
Respiratory bronchiole is lined by low columnar / cuboidal epithelium,
smooth muscle layer, thin layer of adventitia
Alveoli are lined by type I, type II pneumocytes
TONGUE
Mucosa consists
o Stratified squamous non keratinized epithelium
o Underlying lamina propria with C.T & Von Ebners glands(serous
glands)
Mucosal projections are papilla
4 types
o Fungiform ,fungiform , foliate(absent in Humans), circumvallate
papilla
Core of the tongue consists of skeletal muscle sectioned in longitudinal,
transverse, oblique planes
PAROTID / SEROUS SALIVARY GLAND
Surrounded by C.T capsule
Divided into lobes & lobules
Serous acinus
o Lined by darkly stained pyramidal cells,rounded nucleus towards
centre of cell, Narrow lumen, Myoepithelial cells
Ducts are intercalated ducts, striated ducts, interlobular ducts
Blood vessels & nerves present in the septa & with in lobules
SUBMANDIBULAR / MIXED SALIVARY GLAND
Consists of
o Serous acini (predominant)
o Mucous acini with large lumen, light stained cells, flattened
basal nucleus
o Some mucous acinus capped with crescent shaped serous
Demilunes seen
Myoepithelial cells seen in the wall of acini
Ducts are intercalated ducts, striated ducts, interlobular ducts
Blood vessels & nerves present in the septa & with in lobules
SUBLINGUAL / MUCOUS SALIVARY GLAND
Consists of
o Mucous acini (predominant)
o Some mucous acinus capped with crescent shaped serous
Demilunes seen
o Few serous acini seen
Myoepithelial cells seen in the wall of acini
Ducts are intercalated ducts which are short or absent, interlobular
ducts are non striated, interlobular ducts are present
Blood vessels & nerves present in the septa & with in lobules
THYROID GLAND
Thyroid follicles lined by cuboidal epithelium , filled with pinkish
colloid
Parafollicular cells or c- cells present in between the follicles or
between the follicular cells & basement membrane secretes
calcitonin
Numerous blood capillaries
PITUITARY GLAND
Anterior lobe
o Clumps of cells with sinusoids in between the clumps
o Chromophils ( Acidophils, Basophils), chromophobes
Posterior lobe
o Unmyelinated nerve fibres, pituicytes (Neuroglial cells)
o Herrings bodies store neurotransmitters
Intermediate lobe
o Colloid filled vesicle like structures
Intra glandular cleft is remnant of Rathke’s pouch
CORNEA
5 layers
Anterior corneal epithelium is stratified squamous non keratinized
epithelium
Anterior limiting membrane/Bowmans membrane
Corneal stroma consists of regularly arranged collagen fibres
Posterior limiting membrane / Descemet’s membrane
Posterior corneal epithelium made up of simple squamous epithelium
RETINA
10 layers
Pigment layer
Layer of rods & cones
Outer limiting membrane(outer processes of Mullers cells)
Outer nuclear layer (Nuclei of rods & cones)
Outer plexiform layer(synapses between Rods & Cones with Bipolar
cells)
Inner nuclear layer(Nuclei of Bipolar cells, Muller’s cells, Amacrine cells,
Horizontal cells)
Inner plexiform layer(synapses between Bipolar, Amacrine, Ganglionic
cells)
Layer of ganglionic cells
Layer of optic nerve fibres( axons of Ganglionic cells)
Inner limiting membrane( inner processes of mullers cells)