Main
Main
In response to the COVID-19 pandemic, several international initiatives have been developed to strengthen and reform Lancet Glob Health 2022;
the global architecture for pandemic preparedness and response, including proposals for a pandemic treaty, a Pandemic 10: e1675–83
Fund, and mechanisms for equitable access to medical countermeasures. These initiatives seek to make use of crucial Published Online
September 27, 2022
lessons gleaned from the ongoing pandemic by addressing gaps in health security and traditional public health
https://doi.org/10.1016/
functions. However, there has been insufficient consideration of the vital role of universal health coverage in sustainably S2214-109X(22)00341-2
mitigating outbreaks, and the importance of robust primary health care in equitably and efficiently safeguarding Department of Health Policy,
communities from future health threats. The international community should not repeat the mistakes of past health London School of Economics
security efforts that ultimately contributed to the rapid spread of the COVID-19 pandemic and disproportionately and Political Science, London,
UK (A Lal MSc); Department of
affected vulnerable and marginalised populations, especially by overlooking the importance of coherent, multisectoral
Epidemiology, Boston
health systems. This Health Policy paper outlines major (although often neglected) gaps in pandemic preparedness University School of Public
and response, which are applicable to broader health emergency preparedness and response efforts, and identifies Health, Boston, MA, USA
opportunities to reconceptualise health security by scaling up universal health coverage. We then offer a comprehensive (S M Abdalla MBBS DrPH);
Center for Interdisciplinary
set of recommendations to help inform the development of key pandemic preparedness and response proposals across
Research, Saveetha Institute of
three themes—governance, financing, and supporting initiatives. By identifying approaches that simultaneously Medical and Technical Sciences,
strengthen health systems through global health security and universal health coverage, we aim to provide tangible Saveetha University, Chennai,
solutions that equitably meet the needs of all communities while ensuring resilience to future pandemic threats. India (V K Chattu MD MPH);
Department of Community
Medicine, Faculty of Medicine,
Introduction have long been off-track. Where progress on UHC had Datta Meghe Institute of
The health and wellbeing of populations worldwide are been made, the focus has largely been on expanding Medical Sciences, Wardha,
at a pivotal, yet precarious, moment. Although the financial coverage through health insurance rather than India (V K Chattu); Department
of Occupational Science and
COVID-19 pandemic unveiled health inequities and ensuring available, accessible, acceptable, and high-
Occupational Therapy, Temerty
exposed striking weaknesses in pandemic preparedness quality health services.5 Few countries had invested in Faculty of Medicine, University
and response, our collective failure to build resilient and integrated health systems that were equipped to support of Toronto, Toronto, ON,
responsive health systems that meet the needs of all both global health security and UHC.6 Canada (V K Chattu); O’Neill
Institute for National and
should have come as no surprise. These weaknesses go Health systems can be considered as the means by Global Health Law,
beyond pandemic preparedness and response, and also which health priorities, including global health security Georgetown University Law
apply to health emergency preparedness and response and UHC, can be operationalised. Strengthening of Center, Washington, DC, USA
more broadly.1 The rapid spread of the COVID-19 health systems is a necessary component of epidemic (N A Erondu PhD, A Phelan SJD);
Global Health Institute for
pandemic simply underscored long-existing gaps and and pandemic preparedness and response, supporting Disease Elimination, United
bottlenecks in the global health security architecture that essential public health functions including robust health Arab Emirates Global Health
impeded public health systems from preventing, infrastructure, trained and protected health-care workers, Programme, Chatham House,
detecting, and responding to international infectious adequate funding, reliable supply chains, and evidence- London, UK (N A Erondu);
Graduate Institute of Health
disease threats. Health systems were further weakened based planning and coordination. Effective and accessible and Biotechnology Law, Taipei
by chronic underinvestments in national and subnational primary health care can be a key approach for creating Medical University, Taipei,
health systems over the years, including inadequate cohesion between global health security and UHC. Taiwan (T-L Lee SJD);
mechanisms for real-time epidemiological surveillance Primary health care is the range of people-centred Department of Epidemiology
and Biostatistics, Faculty of
and monitoring during health emergencies.2 essential health services and goods that support the Medical and Health Sciences,
Universal health coverage (UHC) is an equally majority of a person’s health needs over their lifetime. University of Auckland,
important, although often overlooked, element in Previous studies contend that the lack of adequate Auckland, New Zealand
preventing health emergencies. Although UHC is primary health care might have jeopardised the ability of (S Singh MBChB); Health
System Governance Team,
technically focused on mitigating the financial burden countries to mount an equitable response to COVID-19 Department of Universal
of health care, it has often been used to describe the or ensure resilience in the face of complex, competing Health Coverage/Health
wider set of interventions necessary to ensure that health and economic crises.7 Systems, Regional Office for
the Eastern Mediterranean,
all people have access to comprehensive health Several initiatives have been launched in the wake
World Health Organization,
services. International commitments to achieve UHC, of COVID-19 to better prepare for and respond to both Cairo, Egypt
strengthened through the UN Sustainable Development the current pandemic and future health threats. (H Abou-Taleb MD DrPH);
Goal (SDG) 3.8 target to achieve UHC3 and the political Three major reports recommended revisions to the Ministry of Social Development
and Family, Santiago, Chile
declaration of the UN High-Level Meeting on UHC,4 international governance of global health security,
worldwide are chronically underfunded, disjointed, and COVID-19 symptoms, and availability of intensive care (J Vega Morales MD DrPH);
inequitable.15,16 Investments in early-warning systems units was considerably reduced among poor and Black Center for Global Health
Science and Security,
and advanced laboratories are undoubtedly needed, communities.29 In the USA, racial and socioeconomic Georgetown University
such as through initiatives like the WHO Hub for disparities were reported in COVID-19 infection and Medical Center, Washington,
Pandemic and Epidemic Intelligence. However, these death rates; marginalised groups also experienced DC, USA (A Phelan)
investments will not be sufficient unless concretely tied barriers in accessing prevention and treatment. Income Correspondence to:
to broader initiatives that strengthen health systems and disparities have been reflected in the scarcity of beds in Arush Lal, Department of Health
Policy, London School of
are supported by UHC.17 For example, in the first intensive care units, particularly in rural areas.30
Economics and Political Science,
6 months of the COVID-19 pandemic, about 90% of London WC2A 2AE, UK
countries reported disruptions to essential health A lack of inclusive and equitable engagement [email protected]
services, and many individuals were unable to access mechanisms For more on WHO Hub for
nearby health centres or afford testing.18,19 These Because global response to health emergencies is Pandemic and Epidemic
Intelligence see
disruptions can largely be attributed to inadequate primarily coordinated at the nation-state level, the absence
https://pandemichub.who.int
progress on UHC and poor consideration of the role of of engagement from local communities and civil societies
primary health care in preparedness and response. Less undermines equitable governance that represents all
than half of the countries in one major analysis included perspectives.31,32 Although these issues have been well
the maintenance of health services in their national documented even before the pandemic, they risk being
COVID-19 strategic plans,20 and chronic distrust of further exacerbated in the wake of the COVID-19
health-care providers impeded the response in many pandemic,33 because an increasing focus on strengthening
communities.21 WHO reported that up to 180 000 health global health security initiatives tends to sideline much
and care workers might have died from COVID-19 in needed investment in UHC. Meanwhile, global
the period between January, 2020, and May, 2021, often administrations pursued a particular notion of equity by
from poor working conditions, while inadequate focusing solely on addressing inequitable access to
planning and workforce capacity led to the destruction medical countermeasures among countries (eg, vaccine
of hundreds of thousands of vaccine doses in high- equity) but overlooked in-country disparities in delivering
income and low-income countries alike.22,23 These issues life-saving COVID-19 supplies and maintaining routine
go beyond the scope of traditional global health security health services.34
and offer a cautionary tale about the pitfalls of neglecting These challenges can be addressed by improving whole-
primary health care, underpinned by commitments to of-society representation in health systems as a core
UHC, in future pandemic preparedness and response component of future pandemic preparedness and
initiatives. response initiatives. Leveraging diverse, multistakeholder
governance is a key factor for better delivering UHC-
Gaps in mitigating socioeconomic factors related interventions.15 Improved delivery includes
The prevalence of unprepared health systems partly stems expanding and strengthening primary health care to
from prioritising clinical care at the expense of promoting support health emergency preparedness and response—
healthy populations and societies. As a result, many social, for example, by removing user fees in health facilities,
political, and environmental determinants of health, making medical countermeasures (eg, diagnostics and
such as economic inequality, racism, gender inequity, therapeutics) free, scaling up a robust community health
and—increasingly—climate change, remain neglected workforce, and leveraging primary care data and social
throughout pandemic preparedness initiatives.24,25 Many insights.
reasons exist that account for this oversight, including
patronising modes of operation and a power imbalance of Emerging opportunities in pandemic
funding initiatives between high-income and low-income preparedness and response
countries, which often privilege global initiatives over the Aligning global health security and UHC capacities
priorities of local communities or less powerful nations. Although most countries have had difficulties in
The poor understanding of the foundational determinants sustaining an effective response over the duration of the
of health has been particularly evident in the absence of pandemic, initial studies suggest that health systems that
support for vulnerable populations, including a striking could effectively leverage both robust global health
paucity of social and economic protection policies at the security core capacities (eg, surveillance, laboratories, and
domestic level and of solidarity-based mechanisms to risk communication) and fundamental UHC interventions
provide affordable medical supplies at the international (eg, primary health care, affordable medicines and
level.26–28 supplies, accessible health facilities, and community
Such inadequacies disproportionately affected groups health workers) were often in a better position to protect
of individuals who were already marginalised, with their citizens against the social and economic impacts of
factors such as poverty influencing vaccine access the pandemic.6,35–37 For example, researchers in the USA
within countries and globally. In Brazil, low-income have argued that UHC could have averted more than
populations had reduced access to health care for 212 000 deaths and US$105 billion in just 2020 alone.38
Mitigating wider determinants of health initiatives spanning health and finance ministries,
Countries found that they could not rely on isolated mechanisms that empower marginalised communities
technological innovations, standardised solutions, or through cooperation across regional blocs or low-income
fragmented health programmes when addressing long- countries, and civil society engagement) that diversify
standing gaps in emergency preparedness. The leadership to balance power and safeguard equity at all
COVID-19 pandemic has therefore incetivised fresh calls levels.48 Governments should also develop costed
to address the systemic political, social, environmental, National Action Plans for Health Security that accurately
and economic determinants and effects of public health estimate the resources necessary for pandemic
threats. Examples of this increasing awareness should preparedness and response and to allocate responsibility
include plans to mitigate the anthropogenic drivers of to relevant agencies and donor programmes.49 Ultimately,
zoonotic spillovers and other outbreaks (eg, climate these emerging opportunities are only achievable
change, changes in land use, and antimicrobial through renewed progress on UHC.
resistance) and invest in health systems that advance
both global health security and UHC. Strong investments Recommendations
in social security and safety nets as well as a primary Governance
health-care approach to pandemic preparedness and The Working Group on Strengthening WHO
response39,40 are required to effectively address these Preparedness and Response to Health Emergencies draft
determinants of health.41 report10 found consensus among member states that
many aspects of pandemic preparedness and response,
Developing equitable and inclusive pandemic such as equity (described as “the core of the breakdown in
preparedness and response mechanisms the current system”10), were not adequately addressed
Sustained political leadership and effective governance under the existing IHR and could instead be best enforced
were key factors in COVID-19 response and will con through new international legal instruments, such as a
tinue to influence future pandemic preparedness and pandemic treaty. In a promising shift from conventional
response. Good governance requires that health health security approaches, the working group called for
decision-making processes and institutions at national the need to “achieve universal health coverage and health
and international levels are accountable, transparent, system strengthening, which includes the enhancement
equitable, inclusive, participatory, and consistent with of primary health care, the health workforce and social
the rule of law.42,43 These principles can inform the protection”.10 Accordingly, negotiations for the IHR and
range of reforms to global governance for pandemic pandemic treaty have echoed these same calls to move
preparedness and response (eg, revisions to the IHR, beyond the status quo in health security.50 In this way,
global financing, and equitable mechanisms for global legal and policy reforms for pandemic preparedness and
public goods) currently being explored. Good governance response can reconceptualise solutions that advance both
can also be reflected in the standardised tools that global health security and UHC through resilient health
researchers use to assess countries’ performance in systems. The success of a new international instrument
responding to health threats.44 Many analyses have for pandemic preparedness and response to prevent the
shown the paucity of metrics to explain why some next health crisis will depend on whether it recognises
countries performed well and others poorly in controlling the gaps in health systems as key contributors to the
the COVID-19 pandemic; political and societal indicators exacerbation of health threats, and whether it responds to
could therefore be included in tools such as the Joint these challenges by mandating that traditional infectious
External Evaluations, which until now have relied heavily disease interventions be implemented together with the
on biosafety and biosecurity when ranking countries’ multisectoral, comprehensive, and proactive interventions
preparedness and readiness. made possible by UHC.
Holistic and modernised approaches to health Furthermore, the inability to achieve equity should be
emergency prevention, preparedness, response, and remedied through legal reforms based on a human
recovery include being equipped to support equitable rights approach.51 Such an approach includes ensuring
and resilient health systems that can promote essential equitable access to medical counter measures and
public health functions together with emergency risk affordable medicines and supplies through the full use
management, and mitigate market failures in research of flexibilities and waivers for public health, such as
and development of medical countermeasures. those under the Agreement on Trade-Related Aspects
Global health security efforts could actively address gaps of Intellectual Property Rights.52,53 Through diplomatic
in health legislation, incorporating the protection of and legislative means, an instrument for pandemic
public health and human rights, and enshrining preparedness and response and more enforceable IHR
accountable and transparent decision making consistent amendments provide novel opportunities to codify and
with the rule of law.45–47 These efforts could be prenegotiate obligations and mechanisms for equity in
strengthened by bold and inclusive institutional the development and distribution of vaccines,
arrangements (eg, multisectoral, whole-of-government diagnostics, personal protective equipment, and
Fostering global solidarity, such as by funding the multisectoral representatives at the national level,
common goods for health, is an overlooked role of including ministries, multilateral offices, and civil society;
global health security financing. Common goods are these teams could be established as standing coordination
interventions that require collective financing and include bodies and integrated within national IHR focal points
investing in essential public health functions, building to support prevention, preparedness, response, and
local health systems, and incetivising UHC.64 To ensure recovery. Such an approach can help maintain essential
the provision of common goods for health, WHO health services, ensure sustainable workforce surge
member states need to support proposals for a substantial staffing through training and remuneration,69 empower
increase (at least 50%) in assessed contributions to WHO, low-income and middle-income countries in bilateral or
and provide the organisation with non-earmarked multilateral negotiations, and harmonise emergency and
funding, as proposed by the Working Group on routine data to guide decision making.70–72
Sustainable Financing.65 All efforts should be made to Follow-on iterations of the ACT Accelerator should
ensure that these funds come from equitable apply a holistic definition of equity beyond merely
contributions of high-income countries, donors, and considering disparities at the nation-state level between
private sector partners, and that clear enforceability high-income and low-income countries. This means
mechanisms exist for all participating stakeholders. taking a human rights approach to in-country disparities
Pandemic preparedness and response financing exacerbated by emergencies, such as mitigating gender
should contribute towards pooled funding to sustain barriers and inequities due to socioeconomic status,
health capacities through primary health care, because enforcing collection of disaggregated data that explicitly
outbreaks begin and end at the local level; its design track intersectional inequities across vulnerable com
should thus be centred on community health workers munities, and safeguarding freedom of press and speech
and services.66 Regionally, these people and services can to ensure accurate and timely health information during
support the expansion of affordable and accessible emergencies.66,73,74 Such efforts should be affirmed and
essential medicines and supplies through pooled closely monitored by the newly-proposed WHO Global
procurement mechanisms, such as the Strategic Fund of Health Emergency Council.
the Pan American Health Organization, and mobilise Pandemic preparedness and response initiatives, such
financial resources for social protection during health as the Global Health Security Agenda, should leverage
emergencies. Domestically, removing user fees UHC and social protection to support traditional health
at health facilities, delinking health insurance from security core capacities.75–77 Other high-profile, donor-
employment, and funding health promotion are crucial driven global health security programmes (eg, the US
factors that could further enable the operationalisation of President’s Emergency Plan for AIDS Relief, the Global
UHC to better support broader preparedness and Fund to Fight AIDS, Tuberculosis and Malaria, or the
response financing.67,68 Coalition for Epidemic Preparedness Innovations) should
promote health systems resilience in low-income
Supporting initiatives countries and fragile and conflict-affected states, in
Programmes designed to address health security accordance with self-identified community and national
challenges have been heavily influenced by the COVID-19 priorities.78,79 Resilience can be further achieved by
pandemic. As pandemic preparedness and response strengthening primary health care as a way to foster
initiatives are redesigned to better cope with future greater alignment across pandemic preparedness and
health threats, it is key they incorporate UHC principles response spending and objectives. The governance and
by scaling up people-centred health systems. frameworks used to guide future health emergency
The ACT Accelerator attempted to leverage its Health response mechanisms should be rooted in whole-of-
Systems and Response Connector pillar to better support society and multisectoral structures, including diverse
in-country integration and delivery of COVID-19 civil society and community-led organisations from low-
countermeasures, such as vaccines, diagnostics, and income countries, to achieve equity and support long-
therapeutics.12 However, the pillar was developed too late, term goals for both global health security and UHC, as
received too little funding, and struggled to effectively suggested by the Global Preparedness Monitoring Board.80
serve as a supporting foundation for the other pillars,
such as the COVID-19 Vaccines Global Access for Conclusions
equitable vaccine procurement. Furthermore, the strategy In the wake of the COVID-19 pandemic, there have
took a myopic view of the role of health systems, focusing been multiple reports, reviews, and proposed initiatives.
on personal protective equipment for health workers However, the global response has been debilitated by
while neglecting other crucial interventions, such as an alarming shortage of timely action and investment.
accessible health facilities and proactive community Although the push towards global health security has
engagement. Future mechanisms should leverage the helped make the case for global cooperation to counter
Health Systems and Response Connector’s model of public health threats, such efforts have largely neglected
country coordination teams, which consisted of to consider how health systems function within
countries. Health systems designed for UHC have been Vice Chair of the Board of Directors for Women in Global Health and a
shown to support communities more equitably through representative of the Platform for ACT-A Civil Society and Community
Representatives.
primary health care. Future pandemic preparedness
and response mechanisms should prioritise health References
1 WHO. 10 proposals to build a safer world together. Strengthening
systems strengthening that simultaneously leverages the global architecture for health emergency preparedness,
global health security and UHC to ensure long-term response and resilience. Geneva: World Health Organization, 2022.
resilience and equity, particularly through core https://www.who.int/publications/m/item/10-proposals-to-build-a-
safer-world-together---strengthening-the-global-architecture-for-
capacities that are most vulnerable during health health-emergency-preparedness--response-andresilience--white-
emergencies, such as a robust health workorce and paper-for-consultation--june-2022 (accessed Sept 14, 2022).
sustained essential health services. 2 The Independent Panel for Pandemic Preparedness and Response.
COVID-19: make it the last pandemic. May, 2021. https://
There is a need for multistakeholder and inclusive theindependentpanel.org/mainreport/#download-main-report
governance for pandemic preparedness and response (accessed June 22, 2022).
through legal and policy mechanisms, including through 3 UN. SDG indicators. Goal 3, target 3.8. https://unstats.un.org/sdgs/
metadata/?Text=&Goal=3&Target=3.8 (accessed Sept 14, 2022).
a binding pandemic treaty and enforceable IHR 4 UN General Assembly. Political declaration of the high-level meeting
amendments, that considers the breadth of health systems on universal health coverage. Oct 18, 2019. https://undocs.org/en/A/
interventions needed to prevent future health emergencies. RES/74/2 (accessed Sept 14, 2022).
Sustainable financing through the proposed Pandemic 5 UHC2030. State of commitment to universal health coverage:
synthesis 2021. https://www.uhc2030.org/fileadmin/uploads/
Fund and common goods for health are required to uhc2030/Documents/Key_Issues/State_of_UHC/Synthesis_2021_
simultaneously advance global health security and UHC final_web_EN.pdf (accessed June 22, 2022).
in all countries while supporting the most marginalised 6 Lal A, Erondu NA, Heymann DL, Gitahi G, Yates R. Fragmented
health systems in COVID-19: rectifying the misalignment between
people and communities, particularly through targeted global health security and universal health coverage. Lancet 2021;
and coherent investments that support primary health 397: 61–67.
care. Health security initiatives and strengthened response 7 Haldane V, De Foo C, Abdalla SM, et al. Health systems resilience
in managing the COVID-19 pandemic: lessons from 28 countries.
mechanisms like the ACT Accelerator should also leverage Nat Med 2021; 27: 964–80.
diverse stakeholders and all parts of the health system 8 WHO. Report of the Review Committee on the functioning of the
through essential public health functions to effectively International Health Regulations (2005) during the COVID-19
response. April 30, 2021. https://www.who.int/publications/m/
control future outbreaks. item/a74-9-who-s-work-in-health-emergencies (accessed
Ultimately, high-level political commitment for health June 22, 2022).
systems, brokered through effective health diplomacy and 9 WHO. IOAC interim report on WHO’s response to COVID-19.
Feb 29, 2020. https://www.who.int/publications/m/item/ioac-
inclusive global leadership, is essential for ensuring equity interim-report-on-who-s-response-to-covid-19 (accessed
in all pandemic preparedness and response interventions. June 22, 2022).
The UN High-Level Meeting on UHC and the UN High- 10 WHO. Draft report of the Member States Working Group on
strengthening WHO preparedness and response to health
Level Meeting on pandemic prevention, preparedness, emergencies to the special session of the World Health Assembly.
and response (both taking place in 2023) should therefore Nov 12, 2021. https://apps.who.int/gb/wgpr/pdf_files/wgpr5/A_
serve as important, complementary milestones to ensure WGPR5_2-en.pdf (accessed June 22, 2022).
11 G20 High Level Independent Panel on Financing the Global
synergies between the goals of global health security and Commons for Pandemic Preparedness and Response. A global deal
UHC, and foster for resilient, equitable health systems. for our pandemic age. June, 2021. https://pandemic-financing.org/
Dedicated investments in strengthening health emergency report/key-proposals-and-roadmap/ (accessed June 22, 2022).
architecture, particularly through primary health care, can 12 Usher AD. New budget and strategy for ACT-A. Lancet 2021; 398: 1677.
13 UN General Assembly. High-level meeting on pandemic
enable collective action to counter the false dichotomies prevention, preparedness and response. July 29, 2022. https://
between global health security and UHC, ensuring the documents-dds-ny.un.org/doc/UNDOC/LTD/N22/444/95/pdf/
world is better equipped to deal with multifaceted public N2244495.pdf?OpenElement (accessed Sept 14, 2022).
14 WHO. WHO Director-General’s opening remarks at the President
health threats. Reconceptualising pandemic preparedness of the UN General Assembly meeting on IPPPR. July 28, 2021.
and response in this way can not only strengthen the basic https://www.who.int/director-general/speeches/detail/who-director-
foundations of global health, but also safeguard our general-s-opening-remarks-at-the-president-of-the-un-general-
assembly-meeting-on-ipppr (accessed June 22, 2022).
shared path towards good health and wellbeing for years 15 Lal A. Opinion: global health security must be tied to health
to come. systems. Devex, June 17, 2021. https://www.devex.com/news/
opinion-global-health-security-must-be-tied-to-health-systems-99937
Contributors
(accessed June 22, 2022).
AL conceptualised the paper. AL and AP developed the initial outline,
16 Spicer N, Agyepong I, Ottersen T, Jahn A, Ooms G. ‘It’s far too
coordinated coauthors’ inputs, and developed the first draft of the
complicated’: why fragmentation persists in global health.
manuscript after input from the wider team. All authors critically Global Health 2020; 16: 60.
reviewed, revised, and approved the final draft of the manuscript.
17 Woodcock A. Coronavirus: Boris Johnson calls for global pandemic
AL finalised the draft and coordinated the submission process. early warning system. The Independent, Sept 26, 2020. https://www.
Declaration of interests independent.co.uk/news/uk/politics/boris-johnson-united-nations-
We declare no competing interests. coronavirus-pandemic-b615222.html (accessed June 22, 2022).
18 WHO. COVID-19 continues to disrupt essential health services in
Acknowledgments 90% of countries. April 23, 2021. https://www.who.int/news/
We thank Kayla Zamanian for proofreading the manuscript. AP received item/23-04-2021-covid-19-continues-to-disrupt-essential-health-
funding from the Carnegie Corporation of New York (G-21-58414). AL is services-in-90-of-countries (accessed June 22, 2022).
19 WHO. The cost of inaction: COVID-19-related service disruptions 42 WHO. Advancing the right to health: the vital role of law. Geneva:
could cause hundreds of thousands of extra deaths from HIV. World Health Organization, 2016. https://apps.who.int/iris/
May 11, 2020. https://www.who.int/news/item/11-05-2020-the-cost-of- handle/10665/252815 (accessed June 22, 2022).
inaction-covid-19-related-service-disruptions-could-cause-hundreds- 43 Burgess RA, Osborne RH, Yongabi KA, et al. The COVID-19
of-thousands-of-extra-deaths-from-hiv (accessed June 22, 2022). vaccines rush: participatory community engagement matters more
20 Mustafa S, Zhang Y, Zibwowa Z, et al. COVID-19 preparedness and than ever. Lancet 2021; 397: 8–10.
response plans from 106 countries: a review from a health systems 44 Haider N, Yavlinsky A, Chang Y-M, et al. The Global Health Security
resilience perspective. Health Policy Plan 2022; 37: 255–68. index and Joint External Evaluation score for health preparedness
21 Sturmberg JP, Tsasis P, Hoemeke L. COVID-19—an opportunity to are not correlated with countries’ COVID-19 detection response time
redesign health policy thinking. Int J Health Policy Manag 2022; and mortality outcome. Epidemiol Infect 2020; 148: e210.
11: 409–13. 45 Ng NY, Ruger JP. Global health governance at a crossroads.
22 UN. Up to 180 000 health workers may have died from COVID-19. Glob Health Gov 2011; 3: 1–37.
UN News, Oct 21, 2021. https://news.un.org/en/story/2021/10/ 46 Brown GW. Multisectoralism, participation, and stakeholder
1103642 (accessed June 22, 2022). effectiveness: increasing the role of nonstate actors in the global
23 Mahase E. COVID-19: countries dump vaccines as demand slumps fund to fight AIDS, tuberculosis, and malaria. Glob Gov 2009;
and sharing proves difficult. BMJ 2021; 374: n1893. 15: 169–77.
24 Abdalla SM, Maani N, Ettman CK, Galea S. Claiming health as a 47 Pham PN, Vinck P, Weinstein HM. Human rights, transitional
public good in the post-COVID-19 era. Development (Rome) 2020; justice, public health and social reconstruction. Soc Sci Med 2010;
63: 200–04. 70: 98–105.
25 Marten R, Yangchen S, Campbell-Lendrum D, Prats EV, Neira MP, 48 WHO. Health systems for health security: a framework for
Ghaffar A. Climate change: an urgent priority for health policy and developing capacities for International Health Regulations, and
systems research. Health Policy Plan 2021; 36: 218–20. components in health systems and other sectors that work in
26 Barkley S, Marten R, Reynolds T, et al. Primary health care: synergy to meet the demands imposed by health emergencies.
realizing the vision. Bull World Health Organ 2020; 98: 727–727A. Geneva: World Health Organization, 2021. https://apps.who.int/
27 Meier BM, Bueno de Mesquita J, Sekalala S. The pandemic treaty as iris/handle/10665/342006 (accessed June 22, 2022).
a framework for global solidarity: extraterritorial human rights 49 Lee CT, Katz R, Eaneff S, Mahar M, Ojo O. Action-based costing for
obligations in global health governance. Bill of Health, Oct 13, 2021. national action plans for health security: accelerating progress
https://blog.petrieflom.law.harvard.edu/2021/10/13/pandemic- toward the International Health Regulations (2005). Health Secur
treaty-extraterritorial-obligations/ (accessed June 22, 2022). 2020; 18: S53–63.
28 Šehović AB, Govender K. Addressing COVID-19 vulnerabilities: 50 Fletcher ER. ‘Zero Draft’ report on WHO reform punts pandemic
how do we achieve global health security in an inequitable world. treaty forward—amidst signals of US warming to initiative.
Glob Public Health 2021; 16: 1198–208. Health Policy Watch, Oct 28, 2021. https://healthpolicy-watch.
29 Pereira RHM, Vieira Braga CK, Mendes Servo L, et al. Geographic news/zero-draft-report-on-who-reform-punts-pandemic-treaty-
access to COVID-19 healthcare in Brazil using a balanced float forward-with-signals-of-us-shift-to-support-initiative/ (accessed
catchment area approach. Soc Sci Med 2021; 273: 113773. June 22, 2022).
30 Kanter GP, Segal AG, Groeneveld PW. Income disparities in access 51 WHO. Anchoring universal health coverage in the right to health:
to critical care services’. Health Aff (Millwood) 2020; 39: 1362–67. what difference would it make? Policy brief. Geneva: World Health
Organization, 2015. https://apps.who.int/iris/handle/10665/199548
31 Rau B. The politics of civil society in confronting HIV/AIDS. Int Aff
(accessed June 22, 2022).
2006; 82: 285–95.
52 Chattu VK, Singh B, Kaur J, Jakovljevic M. COVID-19 vaccine,
32 Gómez EJ, Ruger JP. The global and domestic politics of health
TRIPS, and global health diplomacy: India’s role at the WTO
policy in emerging nations. J Health Polit Policy Law 2015; 40: 3–11.
platform. Biomed Res Int 2021; 2021: 6658070.
33 Patel KCR, Ali S, Hanif W, Khunti K. Learning lessons from
53 Chattu VK, Dave VB, Reddy KS, et al. Advancing African Medicines
COVID-19 to reduce global health inequity. BMJ Opinion,
Agency through global health diplomacy for an equitable
Aug 13, 2021. https://blogs.bmj.com/bmj/2021/08/13/learning-
pan-African universal health coverage: a scoping review.
lessons-from-covid-19-to-reduce-global-health-inequity/ (accessed
Int J Environ Res Public Health 2021; 18: 11758.
June 22, 2022).
54 Hodgson T, Habibi R, Meier BM, Davis S. Human rights must
34 Abdalla SM, Allotey P, Ettman CK, et al. Global equity for global
guide a pandemic treaty. OpinioJuris, Nov 22, 2021. http://
health. G20 Insights, Sept 23, 2021. https://www.g20-insights.org/
opiniojuris.org/2021/11/22/human-rights-must-guide-a-pandemic-
policy_briefs/global-equity-for-global-health/ (accessed June 22, 2022).
treaty/ (accessed June 22, 2022).
35 Malik SM, Barlow A, Johnson B. Reconceptualising health security
55 Rizvi SS, Douglas R, Williams OD, Hill PS. The political economy
in post-COVID-19 world. BMJ Glob Health 2021; 6: e006520.
of universal health coverage: a systematic narrative review.
36 Shroff ZC, Marten R, Vega J, Peters DH, Patcharanarumol W, Health Policy Plan 2020; 35: 364–72.
Ghaffar A. Time to reconceptualise health systems. Lancet 2021;
56 Erondu NA, Martin J, Marten R, Ooms G, Yates R, Heymann DL.
397: 2145.
Building the case for embedding global health security into
37 Assefa Y, Gilks CF, van de Pas R, Reid S, Gete DG, Van Damme W. universal health coverage: a proposal for a unified health system
Reimagining global health systems for the 21st century: lessons that includes public health. Lancet 2018; 392: 1482–86.
from the COVID-19 pandemic. BMJ Glob Health 2021; 6: e004882.
57 Greer SL, Jarman H, Falkenbach M, Massard da Fonseca E, Raj M,
38 Galvani AP, Parpia AS, Pandey A, et al. Universal healthcare as King EJ. Social policy as an integral component of pandemic
pandemic preparedness: the lives and costs that could have been response: learning from COVID-19 in Brazil, Germany, India and
saved during the COVID-19 pandemic. Proc Natl Acad Sci USA 2022; the United States. Glob Public Health 2021; 16: 1209–22.
119: e2200536119.
58 Velásquez G, Syam N. Policy Brief 93, May 2021. A new WHO
39 Carlson CJ, Albery GF, Phelan A. Preparing international international treaty on pandemic preparedness and response: can it
cooperation on pandemic prevention for the Anthropocene. address the needs of the Global South? Geneva: South Centre,
BMJ Glob Health 2021; 6: e004254. May, 2021. https://www.southcentre.int/policy-brief-93-may-2021/
40 Bariş E, Silverman R, Wang H, Zhao F, Pate MA. Walking the talk: (accessed June 22, 2022).
reimagining primary health care after COVID-19. Washington, DC: 59 Labonté R, Wiktorwicz M, Packer C, Ruckert A, Wilson K, Halabi S.
World Bank, 2021. https://openknowledge.worldbank.org/handle/ A pandemic treaty, revised International Health Regulations,
10986/35842 (accessed June 22, 2022). or both? Global Health 2021; 17: 128.
41 Rawaf S, Allen L, Dubois E, et al. 2018. Technical series on primary 60 Bhambra GK. Postcolonial and decolonial dialogues.
health care. Primary health care: closing the gap between public Postcolonial Stud 2014; 17: 115–21.
health and primary care through integration. World Health
61 Rackimuthu S, Narain K, Lal A, et al. Redressing COVID-19 vaccine
Organization, 2018. https://www.who.int/docs/default-source/
inequity amidst booster doses: charting a bold path for global health
primary-health-care-conference/public-health.pdf (accessed
solidarity, together. Global Health 2022; 18: 23.
April 7, 2022).
62 Zhu J. Review of the World Bank Pandemic Emergency Financing 72 Lal A, Ashworth HC, Dada S, Hoemeke L, Tambo E. Optimizing
Facility (PEF) pandemic bond with reform proposals. https://www. pandemic preparedness and response through health information
lse.ac.uk/school-of-public-policy/assets/Documents/Social-Sciences- systems: lessons learned from Ebola to COVID-19.
Response-to-Covid/Jintao-Zhu.pdf (accessed June 22, 2022). Disaster Med Public Health Prep 2022; 16: 333–40.
63 Røttingen J-A, Hvideberg H, Tölö E, Sarda B, Aylward B. Financing 73 Meier BM, Gostin LO. Human rights for health across the United
global health security fairly. Center for Global Development, Nations. Health Hum Rights 2019; 21: 199–204.
April 21, 2021. https://www.cgdev.org/blog/financing-global-health- 74 Bali S, Dhatt R, Lal A, Jama A, Van Daalen K, Sridhar D. Off the back
security-fairly (accessed June 22, 2022). burner: diverse and gender-inclusive decision-making for COVID-19
64 Soucat A, Kickbusch I. Global common goods for health: towards response and recovery. BMJ Glob Health 2020; 5: e002595.
a new framework for global financing. Glob Policy 2020; 75 UHC2030. Action on health systems, for universal health coverage
11: 628–35. and health security. 2021. https://www.uhc2030.org/fileadmin/
65 WHO. Meeting report of the Working Group on Sustainable uploads/uhc2030/Documents/Key_Issues/Advocacy/UHC2030_
Financing. May 9, 2022. https://apps.who.int/gb/wgsf/pdf_files/ Health_systems_narrative__actions_paper.pdf (accessed
wgsf7/WGSF_7_4-en.pdf (accessed June 22, 2022). June 22, 2022).
66 Abiiro GA, De Allegri M. Universal health coverage from multiple 76 Kluge H, Martín-Moreno JM, Emiroglu N, et al. Strengthening
perspectives: a synthesis of conceptual literature and global debates. global health security by embedding the International Health
BMC Int Health Hum Rights 2015; 15: 17. Regulations requirements into national health systems.
67 Global Financing Facility. Beating the DRUM in lower-income BMJ Glob Health 2018; 3 (suppl 1): e000656.
countries: domestic resource use and mobilization for SDG3. 2018. 77 Heymann DL, Chen L, Takemi K, et al. Global health security: the
https://www.globalfinancingfacility.org/sites/gff_new/files/ wider lessons from the west African Ebola virus disease epidemic.
documents/Beating-the-DRUM-in-Lower-Income-Countries_ Lancet 2015; 385: 1884–901.
English.pdf (accessed June 22, 2022). 78 Usher AD. Health systems neglected by COVID-19 donors. Lancet
68 Bitton A, Fifield J, Ratcliffe H, et al. Primary healthcare system 2021; 397: 83.
performance in low-income and middle-income countries: 79 WHO. Building health systems resilience for universal health
a scoping review of the evidence from 2010 to 2017. BMJ Glob Health coverage and health security during the COVID-19 pandemic and
2019; 4 (suppl 8): e001551. beyond: WHO position paper. Geneva: World Health Organization,
69 Deussom R, Lal A, Frymus D, et al. Putting health workers at the 2021. http://apps.who.int/iris/handle/10665/346515 (accessed
centre of health system investments in COVID-19 and beyond. Nov 10, 2021).
Fam Med Community Health 2022; 10: e001449. 80 WHO. From worlds apart to a world prepared: Global Preparedness
70 Hipgrave DB, Kampo A, Pearson L. Health systems in the ACT-A. Monitoring Board report 2021. Geneva: World Health Organization,
Lancet 2021; 397: 1181–82. 2021. https://www.gpmb.org/docs/librariesprovider17/default-
71 Community and civil society representatives to the ACT-A health document-library/gpmb-annual-report-2021.pdf?sfvrsn=44d10dfa_9
systems connector pillar. RE: HSRC strategy update and civil society (accessed June 22, 2022).
participation. Oct 27, 2021. https://covid19advocacy.org/wp-content/
uploads/2021/11/CS-Letter_HSRC-Strategy_28Oct2021.pdf Copyright © 2022 The Author(s). Published by Elsevier Ltd. This is an
(accessed June 22, 2022). Open Access article under the CC BY 4.0 license.