Perpetual Flame
Perpetual Flame
Gabriel Banini
Medical Student, Class of 2022
1
Content
• Tools • ASA Classification
• Oxygen Therapy and Oxygen • Premedication
Delivery Devices • Difficult Airway
• Muscle Relaxants • Fasting Guidelines
• Inhalational Agents • Rapid Sequence Induction
• Intravenous Agents • Triple Manoeuvre
• Fluid and Electrolyte Therapy
• Safe Dose Calculation for Local
Anaesthesia
2
Tools
3
Self Inflating Bag Valve Mask
4
Uses/Indications
• Bag valve mask may be used for emergency ventilation. e.g. during
CPR.
• Bag and valve may be used to ventilate patients with an ET tube or
LMA
• Alternative for failed intubation
5
Contraindications
• Complete upper airway obstruction
• After induction – risk of aspiration
• Severe facial trauma
• Foreign body in the airway. Eg gastric content
6
Complications
• Lung injury from over stretching
• Inflated air in stomach
• Aspiration
7
Management of Difficult Mask Ventilation
• Jaw thrust
• Placement of an oral airway
• Two-person mask ventilation
8
Oropharyngeal Airway
• A curved plastic device that is designed to go over the back of the tongue.
• Estimating the right size: From angle of mouth to the angle of mandible
9
Uses/Indications
• To maintain the airway in unconscious patient by preventing the
tongue from occluding airway
• Aids in airway suctioning
• Conduit for passing devices into the oropharynx
• Prevents tongue bite
10
Contraindications
• Intact gag reflex (conscious or semi-conscious patients) – vomiting
and aspiration
• Oropharyngeal growth
11
Complications
• Vomiting and aspiration in patients with intact gag reflex
• Very long ones can cause airway obstruction
• Trauma to airway
12
Nasopharyngeal Airway
• Estimating the right size: From
the tip of the nose to the tragus
of the ear
13
Uses/Indications
• To maintain the airway patency
• To suction secretions
• Can be used to guide NG tube placement
14
Contraindications
• Bleeding disorder/ History of nosebleed
• Anticoagulation
• Basilar skull fracture
• Growths in the nose or nasopharynx. Eg polyp
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Complications
• Nasal bleeding
• Injury to turbinates
• Sinusitis
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Advantages of NPA over OPA
• Better tolerated in patients with intact gag reflex
• Can be used in the setting of restricted mouth opening. Eg oral
trauma, trismus
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Laryngeal Mask Airway
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Uses/Indications
• To maintain airway
• Used as an alternative to bag-mask ventilation
• Can be used to guide intubation
• Used as an alternative when endotracheal intubation is not successful
19
Contraindications
• Patients at risk of aspiration
• Abnormal lesions or deformities of the supra glottis
• Complete upper airway obstruction
• Restricted mouth opening. Eg oral trauma, trismus
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Complications
• Laryngospasm
• Aspiration – Gagging
21
Advantages of LMA over ET
• Insertion requires less skill
• Dose not require NMB drugs
• Does not require laryngoscopy
• Emergence is smooth
22
Magill Forceps
Uses
• To remove FB from oral cavity
• To pack the throat during oral or
pharyngeal surgery
• To guide ET and NG tube
Complications
• Local trauma esp uvula
• Can burst cuff of ET tube during
passage
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Nasogastric Tube
Uses
• Gastric decompression
• Gastric lavage
• Delivering medication
• Feeding of unconscious patients
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Nasogastric Tube
Contraindication Complications
• Recent nasal surgery • Bleeding
• Severe midface trauma • Oesophageal injury
• Coagulopathy/History of • False passage into trachea
nosebleed
• Oesophageal varices
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Laryngoscope
Parts
- Blade
- Handle
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Laryngoscope
Uses/Indications Contraindications
• Direct laryngoscopy • Epiglotitis – Airway obstruction
• Aid in tracheal intubation • Coagulopathy
• Passing orogastric tubes • Craniofacial trauma
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Spinal Needle
Uses/Indications
• Spinal anaesthesia for surgery
• LP for meningitis
• Delivering antibiotics
• Delivering contrast media for
myelography
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Structured Traversed in Spinal Anesthesia:
Posterior to Anterior
• Skin
• SC fat
• Supraspinous ligament
• Interspinous ligament
• Ligamentum flavum
• Epidural space
• Dura and arachnoid
• Subarachnoid space
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Spinal Needle
Contraindications Complications
• Infection over site • Infection
• Increased ICP • Bleeding
• Coagulopathy • Post dura puncture headache
• Allergy • Cerebral herniation
• Patient’s refusal
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Post Dura Puncture Headache
Prevention Treatment
• Use of smaller gauge spinal • Patient should be kept supine
needles • Adequate hydration
• Use of pencil tip needles • Analgesics. Eg NSAIDs
• Adequate hydration • Caffeine → increases CSF prodn
• Epidural blood patch: injection
of 5 – 20ml of autologous blood
into epidural space at the
puncture site
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Central Venous Catheterization Set
Insertion sites
• Internal jugular vein : B/n the
medial and lateral heads of the
sternocleidomastoid muscle and
lateral to the carotid artery
• Subclavian vein
• Femoral vein
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Central Venous Catheterization Set :
Components
Central Line
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Uses/Indications
• Measurement of CVP
• Limited vascular access
• To administer multiple drugs at same time
• To administer blood and blood products
• To administer parenteral nutrition
• To administer vaso-irritating drugs as KCL, 50% Dex etc
• For taking blood samples
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Complications
Acute Delayed
• Arrhythmias • Sepsis
• Bleeding • Thrombosis
• Pneumothorax
• Damage to thoracic duct,
oesophagus, carotid artery
• Cardiac puncture
• Catheter embolization
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Contraindications
• Uncooperative patient
• Skin infection over puncture site
• Coagulopathy
• Distortion of anatomic landmark
• Thrombus in the intended vein
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IV Cannulae
Colour Size
Orange 14
Grey 16
Green 18
Pink 20
Blue 22
Yellow 24
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IV Cannulae
Uses Complications
• Deliver IVF • Infection
• Deliver blood and blood • Injury
products
• Taking blood samples
• Emergency relieve of tension
pneumothorax
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Endotracheal Tube
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ET- Parts and Functions
• Bevel: The slant portion found at the tip of the tube. The bevel is
usually left-facing. This helps in easy visualization of the vocal cords
and easy access into the trachea during intubation
• Murphy’s Eye: An opening at the side of the ET that functions as a
vent and prevents complete obstruction should the primary distal
opening of the ET tube gets blocked.
• Cuff: Prevents aspiration by occluding the airway
• Pilot line/Inflating tube: Serves as a conduit for air into the cuff.
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ET- Parts and Functions
• Pilot balloon: This is a small bulb with a one way valve to allow air
from the syringe into the cuff through the pilot tube/line. Used to
indicate if the cuff is properly inflated.
• Radiopaque line: For X-ray visualization
• Universal connector: Connect the ET tube to the breathing or
anesthesia systems.
• Stylet: Gives the tube rigidity so that it can be easily placed into the
trachea. It must be removed once the tube has been successfully
passed.
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Endotracheal Tube
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Endotracheal Tube
Indications
• To secure the airway and reduce risk of aspiration
• To deliver inhalational anaesthetic agents
• To deliver oxygen
• Positive pressure ventilation
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Confirming Correct Endotracheal Intubation
• Direct visualization
• Chest movement on ventilation
• Breath sounds on auscultation
• Misting sign
• Capnography – Gold standard
• Bronchoscophy
• Chest X-ray
• O2 Saturation
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Anesthesia Machine
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Anesthesia Machine
Components and Function
• Oxygen Tank: This used oxygen that is delivered to the patient.
• Reservoir Bag: Acts as a reservoir of gases for the patient to breathe.
It can also be used to manually ventilate the patient should it be
necessary.
• Oxygen Flow Meter: Used to regulate the amount of oxygen supplied
to the patient.
• Vapourizer: This takes the liquid form of the inhalational agent and
transforms it into vapour.
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Anesthesia Machine
Components and Function
• Breathing circuit (Hose & Face mask): Used to deliver the inhalational
agent and oxygen from the machine to the patient. It also carries the
expired gases away from the patient.
• Soda Lime Canister: This absorbs the CO2 and water vapour expired
by the patient.
• Pressure Manometer: Indicates the pressure that is within the
breathing circuits
• Display Monitor: Helps the technicians to track the flow of the agent
and to make sure it is consistent
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Oxygen Therapy
• Oxygen therapy is the administration of oxygen at concentrations greater than
that of the surrounding air to patients with breathing disorders who aren’t able to
get them naturally.
• Indications include:
-COPD
-Asthma
-Trauma to respiratory system
-Head trauma
-Heart failure
-Pneumonia
-etc
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Oxygen Delivery Devices
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Nasal Prongs
• Flow rate
- 44% O2 at 6L/min
• Advantages
-Patients can eat, drink and talk while
using them.
-They reduce the risk of carbon dioxide
rebreathing.
• Disadvantage
-Nasal irritation and mucosal drying
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Simple Face Mask/Rebreather Mask
• Flow rate
- 60% O2 at 7 - 8L/min
• Advantages
-Can provide increased delivery of
oxygen for short periods of time.
-Can be used in patients with nasal
irritation or epistasis.
• Disadvantages
-Increases dead space
-Uncomfortable for patients while
eating or talking
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Non Rebreather Mask With Reservoir Bag
• Flow rate
- 70% O2 at 10L/min
• Advantage
-Can provide high concentration of
oxygen for short periods of time.
-Can be used in patients with nasal
irritation or epistasis.
• Disadvantage
-Increases dead space
-Uncomfortable for patients while
eating or talking
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Muscle Relaxants
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Suxamethonium/ Succinylcholine
Class: Depolarizing NMBD
Dose: 1-1.5mg/kg
Advantages Disadvantages
• Fast onset • Muscle pain
• Has short duration of action so • Hyperkalemia → cardiac arrest
can be used for procedures that • ↑↑ intra-ocular, intra-cranial and
intra gastric patients
require only a brief duration of
muscle relaxation • Prolonged neuromuscular block in
some patients (both inherited and
• Effective relaxation acquired)
• Risk of malignant hyperthermia
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Suxamethonium/ Succinylcholine
Contraindications
• Burns patients (hyperkalemia)
• Spinal cord injuries (hyperkalemia)
• Glaucoma (↑ intra-ocular pressure)
• Extensive muscle injury (hyperkalemia)
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Atracurium
Class: Non-depolarizing NMBD
(Benzylisoquinolinium)
Advantages Disadvantages
• Spontaneous degradation • Release histamine → bronchospasm,
(Hoffmann elimination) hence skin reactions
can be used in patients with
organ failure. Eg: Liver and
Kidney failure patients
• Neuromuscular block can be
reversed with Neostigmine
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Atracurium
Contraindications
• Asthma patients
• Peptic ulcer
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Pancuronium & Vecuronium
Class: Non-depolarizing NMBD (Aminosteroid)
Advantages Disadvantages
• Dose not release histamine • Metabolized in end organs
hence can be used in asthma hence cannot be used in
and peptic ulcer patients. patients with organ failure. Eg
• Neuromuscular block can be Liver and Kidney failure patients
reversed with Neostigmine
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Pancuronium Vs Vecuronium Vs Atracurium
• Pancuronium is mainly eliminated by the kidneys hence it is
contraindicated in patients with kidney pathologies. However it may
be used in patients with liver pathologies.
• Vecuronium is mainly metabolized and eliminated by the liver hence
it is contraindicated in patients with liver pathologies. However it may
be used in patients with kidney pathologies.
• Atracurium is eliminated by Hoffmann Elimination (spontaneous
degradation) and plasma esterases hence it can be used in patients
with both liver and kidney pathologies.
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Inhalational Agents
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Halothane
Disadvantages
• Arrhythmogenic
Advantages
• Decreases blood pressure
• Pleasant smell
• Sensitizes myocardial conduction
• Bronchodilation→ good for system to the action of
asthma and COPD patients catecholamines therefore, it
cannot be used with epinephrine
• Does not cause mucus during surgery
production in the airways • Post-operative shivering common
• Non-emetic. • Uterine relaxation →post-partum
• Non-flammable hemorrhage
• Hepatotoxicty
• Increases intra-cranial pressure
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Isoflurane
Advantages Disadvantages
• Coronary vasodilatation → Good • Pungent smell
for patients with coronary artery
disease • Decreases BP
• No increase in ICP → Excellent • Ventilatory depressant
for Neurosurgery.
• Rapid recovery
• Not arrhythmogenic
• Fairly good muscle relaxation
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Intravenous Agents
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Thiopental/ Thiopentone/ Pentothal
Class: Barbiturate
Dose: 4-5mg/kg
Advantages Disadvantages
• Bacteriostatic • Poor analgesic
• Decreases BP
• Dose not increase ICP
• Releases histamine
• Potent anticonvulsant • Not suitable for laryngeal mask
• Low incidence of nausea and airway b’cos the airway reflexes are
preserved.
vomiting • Respiratory depression
• Can precipitate porphyrias. This is
due to increased expression of ALA
Synthase. (NB: Barbiturates are
enzyme inducers)
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Propofol
Class: Phenol
Dose: 2-2.5mg/kg
Advantages Disadvantages
• Does not increase ICP • Painful on injection
• Rapid recovery • Decreases BP
• Antiemetic • Respiratory depression
• Excellent for LMA as it reduces
the airway reflexes
• Safe in porphyria
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Etomidate
Class: Imidazole
Dose: 0.3mg/kg
Advantages Disadvantages
• Very stable on the • Causes cough and hiccups
cardiovascular system • Adrenal suppression
• Causes less respiratory • Can precipitate porphyrias
depression.
(↑↑ALA Synthase)
• Fast onset of action
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Ketamine
Class: Phencyclidine
Dose: IV 1.5 -2mg/kg, IM 4-10mg/kg
Advantages Disadvantages
• Can be administered through • Slow onset
various routes
• Prolonged recovery with
• Produces anterograde amnesia hangover effects
• Good analgesic • Increases ICP
• Does not reduce BP
• Emergence phenomena
• Produces bronchodilation
→ good for asthma and COPD
patients
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Midazolam
Class: Benzodiazepine
Advantages Disadvantages
• Produces anterograde amnesia • Slow onset
• Has mild effects on the • Injection site reactions → pain,
respiratory and cardiovascular swelling, etc
system
• Can be reversed by Flumazenil
in case of overdose
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Sample Question (2020 OSCE)
An asthmatic patient is to undergo anesthesia for a surgical procedure. The
drugs to be used include:
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My Answers and Reasons for Choosing them
• Induction: Ketamine (NB: IV agents are usually used for induction)
-Ketamine produces bronchodilation and therefore suitable for an asthmatic patient.
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Fluid and Electrolyte Therapy
Sample Question with Solution
Calculate the fluid management for an elective hernia repair using the
following information
• Age: 68 years
• Gender: Male
• Weight: 50kgs
• Nil per os for 8 hours
• Duration of operation: 2 hours
• Total blood loss during surgery: 500ml
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Fluid and Electrolyte Therapy
1.Correction of Pre-existing deficits
Maintenance fluid requirement for 50kg:
(4 x 10) + (2 x 10) + (1 x 30)
= 40 + 20 + 30
= 90ml/hr
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Fluid and Electrolyte Therapy
2.Maintenance fluid requirement during surgery
Maintenance fluid requirement for 50kg:
(4 x 10) + (2 x 10) + (1 x 30)
= 40 + 20 + 30
= 90ml/hr
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Fluid and Electrolyte Therapy
3.Third space losses
Hernia repair is a minimal trauma surgery (2ml/kg/hr)
= 2 x 50
= 100ml/hr
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Fluid and Electrolyte Therapy
4.Replacement of blood lost during surgery,
Total blood loss during surgery is 500ml. This can be replaced with:
• 500ml blood
• 500ml colloid
• 1500ml crystalloid
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Safe Dose Calculations with Local Anesthesia
• LIDOCAINE: 1-2%
Dose:
- Plain: 3mg/kg
- With adrenaline: 7mg/kg
• BUPIVACAINE: 0.25-0.5%
Dose: 2.5mg/kg
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Safe Dose Calculations
• Is it safe to give 12ml of 1% plain lidocaine to a 70kg patient? [Plain
lidocaine = 3mg/kg]
*It is safe to give the patient 12ml because the maximum dose that can be
given is 21ml
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Safe Dose Calculations
• Is it safe to give a 70kg patient 30mls of 2% lidocaine with adrenaline?
[Lidocaine with adrenaline = 7mg/kg]
*It is not safe to give the patient 30ml because the maximum dose that can
be given is 24.5ml
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Safe Dose Calculations
• What will be the safe dose in ml for use of 0.5% Bupivacaine for a 30kg
child [Bupivacaine = 2.5mg/kg]
*The safe dose/maximum dose of 0.5% Bupivacaine for a 30kg child is 15ml
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ASA CLASSIFICATION
ASA DEFINITION EXAMPLES
ASA I Healthy patient with no Healthy, non-smoking, no or
systemic disease minimal alcohol
ASA Patient with mild systemic Current smoker, social
II disease, no functional alcohol drinker, pregnancy.,
limitations obesity (<40), well-
controlled HPT/DM
ASA Patient with moderate to MI, CVA, TIA (>3months),
III severe systemic disease with alcohol, dependence, poorly
some functional limitations controlled HPT/DM,
BMI≥40, ESKD on regular
scheduled dialysis,
premature neonate
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ASA CLASSIFICATION
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Aim of Premedication
• To allay anxiety: Benzodiazepines eg. Midazolam
• To reduce secretions in the airway: Anticholinergics eg. Atropine,
Hyoscine
• To produce amnesia: Benzodiazepines eg. Midazolam
• To increase stomach pH and reduce the risk of aspiration
pneumonitis: Sodium citrate, Ranitidine
• To reduce nausea and vomiting: Metoclopramide
• To control pain: NSAIDs (avoid the use of NSAIDs in asthmatic and
peptic ulcer patients)
84
Identification of Difficult Airway
• Patient’s Past Medical & Surgical History
• Physical Examination
• Thyromental Distance
• Mallampati Classification
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Past Medical & Surgical History
• Neck surgeries
• Cervical fixation devices
• Acromegaly
• Ankylosing spondylitis
• Rheumatoid arthritis
• Reduced jaw mobility
• Epiglottitis
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Physical Examination
• Thick short neck
• Stiffness of cervical spine
• Limited mouth opening
• Growth in the oropharynx, airway, neck
• Prominent upper incisors
• Receding chin
• Deviation of the trachea
• Abnormally large breast
87
Thyromental Distance
• Measure from upper edge of thyroid cartilage to chin with the head
fully extended.
• Less than 3 finger breadths (<6cm) is a sign of difficult airway
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Mallampati Score
Breastmilk 4 hours
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Rapid Sequence Induction
This is a method of inducing anesthesia in patients who are at high risk
of aspiration of gastric contents into the lungs. The steps involved are:
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Rapid Sequence Induction
Indications
• Abdominal pathology: Ileus
• Delayed gastric emptying: Trauma, Opioids, Vagotomy
• Incompetent lower esophageal sphincter: GERD, Hiatus hernia
• Pregnancy
• Impaired consciousness → loss of airway reflexes
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Triple Manoeuvre
• Head tilt
• Chin lift
• Jaw Thrust
― Alan Armstrong
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