BCHE4030 Clinical Biochemistry
The Chinese University of Hong Kong
School of Life Sciences
Biochemistry Programme
BCHE4030 Clinical Biochemistry (3 Units)
Post-class exercise
Name: Student ID: Date:
1. List the functions of blood.
2. Distinguish whole blood, plasma, and serum.
3. Identify the general features of red blood cells.
4. Identify the structures of haemoglobin on molecular level.
5. Related haemoglobin to oxygen and carbon dioxide transport.
6. Analyze the oxygen saturation/dissociation/affinity curve.
7. Analyze the cell differentiation scheme of hematopoiesis.
8. Describe the classification criteria of white blood cells.
9. Identify the general features of platelets.
10. Define haemostatic response and list its mechanisms.
11. Define anaemia and relate anaemia to red blood cell (RBC) number and haemoglobin
amount.
12. Describe the major cause of hypochromic anaemia.
13. Relate iron level to the amount of transferrin and ferritin.
14. Explain the concept of iron balance.
15. Describe the processes of RBC destruction or recycling.
16. Differentiate extravascular RBC destruction to intravascular destruction.
17. Identify the causes of hereditary haemalytic anamiea.
18. Describe the major causes of macrocytic anaemia.
19. Explain pernicious anaemia.
20. Identify the general clinical features of leukaemia.
21. Relate Philadelphia chromosome to leukaemia.
22. Define haemophilia.
23. Explain what are haemophilia A and haemophilia B.
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24. Identify the general clinical features of haemophilia.
25. Recognize the X-link genetic pattern of haemophilia A.
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BCHE4030 Clinical Biochemistry
26. Explain the clinical application of total iron binding capacity and its biochemical principle.
27. Relate bilirubin level to haemolytic anamia.
28. Recognize the genetic abnormalities associated to leukaemia.
29. Recognize the classification of leukaemia in terms of pattern of surface markers.
30. Identify the objectives for haemaphilia tests.
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