1.

In clasSification system is
tablet machine movement of 10. Biopharmaceutical
guided by punches are
based on
a) Cams tracks a) Molecular weight,
partition coefficient and
b) Turrets
c) Revolving belts d) None of these
dipole moment
2.
2. In tablet parameter, dissolution and
coating process, inadequate spreading b) Solubility
of the partition co efficient
coating solution before drying causes
a) Orange peel effect c)Solubility, dissolution and permeability
b) Flacking c) Blistering effect d) Crystal structure, partition coefficient and
d) Sticking effect dielectric constant
3. Time required to achive 11. Aquacoat is a solution of
steady state plasma
concentration (Cpss) is depends on a) Ethylcellulose b) Colloidal silica
a) Route of drug administration c) Dextrose
b) Amount of drug administered d) Carboxymethyl cellulose
c) Rate of elimination 12. Choose correct statement for a drug eliminated
d) Plasma half life of a drug by first order kinetic
4. All of the given are official test for evaluation a) Plasma half life is depends on plasma
of tablet dosage form as per I.P. concentration
Except
a) Disintegration b) Weight variation b) Constant amount is eliminated in unit
c) Dissolution d) Colour of tablet time.
5. Nitroglycerin is administered by the c) Constant fraction is eliminated in unit
a) Intradermal route b) Subcutaneous route time
c) Sublingual route d) Intamuscular route d) All of these
6. Adultdose of ibuprofen is 400mg, calculate the 13. Oral route is not suitable
for a drug that is
dose for 6years old child according to dilling's a) Unpalatable in test
rule b) High
a) 150 mg b) 120 mng
pre-systemic metabolism
c) Inadequate absorption form g.i.t
c) 160 mg d) 100 mg d) All of these
7. Measurement of inulin renal clearance is a 14.
"Sticking and Picking" occurs during the tablet
measure of
manufacturing when
a) Effective renal blood flow a) Excessive moisture in the
b) Renal drug excretion rate b) Punch vibration granules
Active renal excretion c) Entrapment of air in
c) d) All of these granules
d) Glomerular filtration rate
15. Insulin
8. Accroding to drug and cosmetic act and rules produces its action through the
barbital is a
a) Nicotinic receptors
phenol b) GABAb receptors
a) Shedule X drug b) Schedule G drug c) GABAa receptors
c) Shedule H drug d) Schedule C drug d) Tyrosine
drugs and cosmetic act and rules the 16. What protein kinase
9. In the does R for in
schedule related to
GMP is.
nomenclature? R/S configuration
a) Shedule M b) Schedule C a) Rectos
d) Schedule H c) Rectusd b) Rectgegen
c) Shedule Y
(InC
d) Rusamenn
 of the following drug
has
oAUTHUA

minimum 27. Which of the

Which
anti-in-f1ammatory activity ? following electromagnetic
radiation has maximum energy ?
Acetaminophen b) Aspirin
a) a) Gamma rays b) X-rays
c) Ibuprofen d) Diclofenac sodium c) IR radiation
walk on surface of water due to d) Radio waves
1sect can 28. Adrug is reported to have a
18.
a) Viscosity b) Surface tension bilogical half-lift of
2 hours. At the end of 8 hours what
c)Refractivity d) Optical activity of the drug's original activity will percentage
19.
Which of the following antibiotic is macrolide
a) 2.5%
remain?
a)Chloramphenicol b) 12.5%
c) 25% d) 6.25%
b) Doxycycline
29. Hansch
c) Oleandomycin analysis is used in
d) Streptomycin
a) Drug desingn b) Enzyme kinetics
20. Stoke's shift is the term associated with c) Drug transport
a) IR spectroscopy d) Receptor binding studies
30. Bitransformation of
b) Fluorescence Spectroscopy drugs usually leads to
c) NMR spectroscopy formation of
d) UV-visible spectroscopy a) Lipophilic metabolites
21, One of the factor
b) Polar metabolites
required for maturation of c) Toxic metabolites
erythrocyes is
a) VitaminA d) Inactive metabolite
31. Which one of the
b) Vitamin B,
cells?
following is a
prokaryotic
c) VitaminD d) Vitamin C
22. a) Bacteria b) Fungi
"Capping" is occurs during the tablet c Protozoa
manufacturing wheen d) Algae
32. Titanium dioxide is used in
a) Excessive moisture in the tablet coating as
b) Punch vibration granules a) Glident b) Lubricant
c) Opacifier d) Plasticizer
c) Entrapment of air in granules 33. Plasma membrane consist
d) All of these mainly
a) Protein embedded in a
5. Which one of the given process require energy bilayer phospholipid
for
absorption of a drug? b) Phospholipid embedded in a
protein
a) Passive diffusion bilayer
b) Active transport c) Carbohydrate embedded in a
protein
c) Faciliated diffusion
bilayer
d) Endocytosis d) Protein embedded in
.
Contraction of gall bladder is due
a
carbohydrate
to bilayer
a) Secretin b) Gastrin 34. In multi-station punching machine, the upper
25
.
c)Enterogastrone d) Cholecystokinin
Which of the following
aswell as lower
a) Cams
punches are connected
aqueous solution wi b) Turrets
have the highest c)WireMeshes d) Revolving belts
pH ?
a) Sodium acetate 35. Usually orally administered drugs are absorbed
b) Sodium chloride from
a) Stomach b) Small intestine
Ammonium phosphate c) Rectum d) Large intestine
26.
d Calcium chloride 36. Nitrazepam can be synthesized from
HO
act as
a) Neutra medium
oxidizing agent in
a) 2-bromo-5aminobenzophenone
b) 2-nitro-5-chloro acetophenone
b) Acidic medium
c) 2-amino-5-nitro cyclohexanone
Alkaline and neutral medium d) 2-amino-5-nitro benzophenone
a Alkaline and acidic medium
37. ddiministered
Which of the following opioid agonist is only 44. Acidic drugus mainly bound with plasma
b) al acid glycoprotein
adiministered
a) Morphine
by parenteral route? a) Albumin
d) Gamma globulin
b) codeine c) Lipoprotein
c) Fentanyl factor responsible for
d) Methadone 45. As per epidemiology
38. 19 carbon basic OCcurrence of diseases
steroidal skeleton is called as
a) Androstane b) Environment
b) Gonane a) Agent
c) Estrane d) Pregane c)Host d) All of the above
39. Karl-fisher is
titration is commonly used for 46. DNA gyrase inhibitor
determination of a) Tetracycline b) Quinolones
a) Water b) Nitrogen c) Monobactum d) Erythromycin
c) Mg containing
d) Protein
compounds 47. Polysaccharides are.
b) Acids
40 Standard calomel
a) Polymers
electrode contains c) Proteins d) Oils
a) 0.1 M KCI b) 1.0 MKCI 48. Retinol is transported in blood bound to.
c) Saturated solution of KCI a) Aporetinol binding protein
d) None of the above b) 2-Globulin c) a-Globulin
41
Lysosomes have a high content of d) Albumnin
a) RNA and DNA b) Fat 49. "Capping" in a tablets occur due to.
c) Hydrolytic enzymes a) Entrapment of Air
d) Fat and protein b) Excessive moisture
42. Ribosomes are produced in c) Increased rate of evaporation
a) Golgi body b) Nucleolus d) None of above
c) Cytoplasm d) Mitochondria 50. Isoquinoline alkaloids
43. The area under serum
are
biosynthesized via
concentration time curve pathway.
of drug represents
a) Shikimic acid-tyrosine
a) The biological half life of the drug b Shikimic acid-tryphophan
b) The amount of drug in the original dosage c) Shikimic acid-cathinone
form d) None of above
c) The amount of drug absorbed
d) The amount of drug excreted in the urine

PRACTICE TEST-2
1-A 2-A 3D 4-D 5-B 6-B 7-D 8-A 9-A 10-C
11 A 12-C 13 D14 A 15-D 16-C 17-A 18-B 19-C 20-B
21-B 22-C 23 B 24 D 25-A 26-D 27- A 28-D 29-A 30-B
31 A 32-C 33 A 34 B 35-B 36-D 37-C 38 A 39-A
39-A 40-B
41-C 42-B 43 C 44-A 45 D 46-B 47-A48-A
49-A 50-B