Anatomy and Physiology of Human Systems
Anatomy and Physiology of Human Systems
Course Description
The course is designed to provide detailed anatomical knowledge of cardiopulmonary,
abdomen and its lymphatics, endocrine system, reproductive system and excretory system
Learning Objectives
Upon successful completion of the course, the student will be able to:
• Describe in detail the cardiopulmonary structures and function of muscles,
ligament, bones, joints, nerves and circulation;
• Explain the abdominal structures, their functions, nerve supply, lymphatics and
blood supply;
• Describe the structures and functions of endocrine system, reproductive system and
excretory system and their blood and nerve supply; and
• Explain the applied anatomy of cardiopulmonary, abdomen and its lymphatics,
endocrine system, reproductive system and excretory system.
Course Contents
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Case Studies on Applied Anatomy of Thorax 2 hours
Teaching Methods
Lecture, demonstration and group discussion
References
1. Snell, R. S. Clinical Anatomy for Medical Students. Boston: Little Brown; 1995.
2. Chaurasia BD. Human Anatomy – Regional and Applied. Vol. 1 (Upper limb and
Thorax). 6th ed. New Delhi: CBS Publishers and Distributors; 2013.
3. Chaurasia BD. Human Anatomy – Regional and Applied. Vol. 2 (Lower limb,
Abdomen and Pelvis). 6th ed. New Delhi: CBS Publishers and Distributors; 2013.
4. Moore KL. Dalley AF. Agur AMR. Clinically Oriented Anatomy. 7h ed. Philadelphia:
Wolters Kluwer Health/Lippincott Williams & Wilkins; 2014.
5. Datta AK, Essentials of human Anatomy: Thorax and Abdomen. 5th ed. Current Books
International: Kolkata.
6. Singh I. Text book of Anatomy with colour atlas: Introduction, Osteology, Upper
Extremity, Lower Extremity. Vol I. New Delhi: Jaypee Brothers; 1996.
7. Singh I. Textbook of Human Osteology. 4th ed. New Delhi: Jaypee Brothers.
8. Standring S, Neil RB and Henry G. Gray's Anatomy: The Anatomical Basis of Clinical
Practice. 40th ed. Edinburgh: Churchill Livingstone/Elsevier; 2008.
9. Poddar S. Bhagat A. Handbook of osteology. 13 ed. Scientific Book Company. 2015.
20
BPT 152 Physiology II (Thorax, Abdomen, Endocrine, Reproductive)
BPT, First Year, Second Semester
Course Description
The course will provide the students about the physiological knowledge of cardiac system,
pulmonary system, gastro-intestinal system, endocrine system, reproductive system, renal
system and skin.
Learning Objectives
By the end of course, students will able to;
• Explain the functional physiological structure and properties of cardiac muscle;
• Explain the cardiac cycle;
• Define and know about ECG;
• Describe the physiological functions of saliva, stomach, Liver, Gall Bladder;
• Explain the functional physiological structure and properties of cardiac muscle;
• Describe cellular respiration;
• Describe the pathways involving oxidation-reduction reactions;
• Describe the process of and factors affecting electron transport chain and ATP
synthesis;
• Describe oxidative stress and antioxidant systems;
• List and define lung volumes and lung capacities;
• List and classify the hormones;
• Describe the physiological function of male and female reproductive system
• Describe the physiological function of kidney; and
• To relate the concept of human physiology in physiotherapy application including
exercises physiology.
Course Contents
21
Unit IV: Endocrine System 6 hours
Introduction to Endocrinology; Hormones-classification of hormones and functions; Applied
physiology
Teaching Methods
Lecture and demonstration
References
1. Guyton AC, Hall JE. Text book of medical physiology. 12th ed. USA: Saunders
Elsevier; 2011.
2. Chaudhuri S K. Concise medical physiology. 6th ed. NCBA.
3. John NA. CC. Chatterjee’s Human Physiology. 12th ed. CBS Publishers and
Distributors.
4. Sembulingam K, Sembulingam P. Essentials of Medical Physiology. 5th ed. Jaypee
Brothers Medical Publishers; 2010.
5. Jain AK. Textbook of Physiology. Vol 1 & 2. 7th ed. Avichal Publishing Company;
2017.
6. Venkatesh D & Sudhakar H H. Basics of Medical physiology. 4th ed. Wolters Kluwer.
22
BPT 153 Biomechanics I (Basic Concepts, Upper Extremity and Thorax)
BPT, First Year, Second Semester
Course Description
The course is designed to provide knowledge about basic concepts in biomechanics. The course
will also cover the detailed aspect of biomechanics related to upper extremity and thorax.
Learning Objectives
At the completion of this course, students should be able to:
Explain the basics of biomechanics including examples;
Explain the joint properties, functions, motions and its pathological effects;
Explain the muscle properties, functions, types of contraction and its pathological
effects;
Describe the normal and abnormal functional anatomy and biomechanics of the
shoulder complex; and
Describe the normal and abnormal functional anatomy and biomechanics of the thorax
and chest walls.
Course Contents
23
Unit V: Wrist and Hand Biomechanics 6 hours
Functional anatomical aspects of the wrist and hand; Kinetics-muscle action at normal ROM
and its Dysfunction
Teaching Methods
Lecture, demonstration and group discussion
References
1. Levangie PK, Norkin C. Joint structure and function: a comprehensive analysis, 5th ed.
FA Davis Company.
2. Brunnstrom. Clinical Kinesiology. 5th edi. Bangalore: Jaypee Brothers Medical
Publishers. Bangalore; 1996.
3. Lippert LS. Clinical Kinesiology for Physical Therapist Assistants. 2nd ed. Bangalore:
FA Davis Company; 1994.
24
BPT 154 Pathology
BPT, First Year, Second Semester
Course Description
This course deals with basic understanding of general pathology and body’s different
pathological process along with basic nature of disease processes from the standpoint of
causation, epidemiology and the structural and functional abnormalities that result.
Learning Objectives
At the end of course, the students will be able to;
• List the causes of cell injury and describe the morphological changes in reversible and
irreversible cell injury;
• Define necrosis, its types, morphological changes and explain the difference with
apoptosis;
• Describe pathologic calcification;
• Define inflammation, its types with examples, responses to inflammation, systemic
effects of inflammation, role of chemical mediators and inflammatory cells in
inflammation;
• Define a granuloma. List the causes of granulomatous inflammation;
• Describe wound healing by primary and secondary intention and factors that influence
wound healing;
• Describe the pathophysiology of oedema. Differentiate from a transudate;
• Describe the pathogenesis of thrombosis, its morphology and fate;
• Define embolism and infarction their types, morphology and consequences;
• Describe chronic venous congestion of lungs and liver and list its morphological
changes;
• Define shock. List its types and explain its aetiopathogenesis with special references to
cardiogenic and septic shock;
• Define dysplasia, carcinoma-in situ, neoplasia and allied definitions;
• Classify neoplasms, difference between benign and malignant neoplasms;
• Describe the fracture healing and its different stages; and
• Explain the etiology, pathogenesis and list the clinical features and complications of
common diseases of cardiovascular system, respiratory system, musculoskeletal
system, endocrine system, Urinary, GIT, hepatic system and skin disorders.
Course Contents
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muscle; Regeneration & repair
B. Respiratory
Chronic obstructive pulmonary disease: Aetiology, pathogenesis and common clinical
manifestations; Bronchiectasis, Bronchial asthma: definition and pathogenesis; Pneumonia:
Types and pathogenesis; T.B.-primary, secondary, morphologic types; Plural diseases: Pleural
effusion and pneumothorax complications; Respiratory failure: Definition and causes
C. Neuropathology
Reaction of nervous tissue to injury, infection & ischaemia; Cerebro-vascular diseases-
Hypoxia, infarction & hemorrhage; Meningitis- Eitopathogenesis and clinical manifestations,
types; Degenerative diseases: Parkinsons disease, motor neuron disease, multiple sclerosis,
Alzheimer disease (Etiology and pathogenesis); Polyneuropathies: Guillian Barre syndrome as
prototype for pathogenesis of polyneuropathy; Spinal cord disorder: Pathogenesis of spinal
cord injury; Brain tumors: Pathogenesis of brain tumors
D. Muscle Diseases
Muscular dystrophy: pathogenesis and clinical features; Hyperplasia, Hypertrophy, Pseudo-
hypertrophy, atrophy: definition; Poliomyelitis: Pathogenesis and clinical features; Myositis
ossificans: Etiology and Pathogenesis
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F. Urinary
Paralytic bladder: Types and pathology; Common UTIs: pathogenesis
G. GI System
GI ulcer: Etiology and pathogenesis; Gastritis: pathogenesis (drug induced)
H. Endocrine System
Thyroid disorders: Etiology and pathogenesis; Diabetes: Etiology, Types, pathogenesis and
complications
I. Hepatic Diseases
Cirrhosis: Etiology, Pathogenesis and clinical features with emphasis to systemic effects of
portal hypertension
J. Skin
Vitiligo: pathogenesis and clinical features, Psoriasis: pathogenesis and clinical features;
Scleroderma: Etiology, pathogenesis and clinical features; SLE: Etiology, pathogenesis and
clinical features
Teaching Methods
Lecture, demonstration and group discussion
References
1. Mohan H. Textbook of pathology. 7th edition. Jaypee Brothers Medical Publishers.
2. Mohan H. Essential pathology for Physiotherapy students. Jaypee Brothers Medical
Publishers; 2018.
3. Underwood JCE, Cross SS. General systemic pathology. 5th edition. Churchill
Livingstone.
4. Kumar, Abbas, Aster. Robbins Textbook of Pathology. 9th edition. Elsevier.
27
BPT 155 Pharmacology
BPT, First Year, Second Semester
Course Description
The students will become familiar with pharmacological principles of therapeutics, and
pharmacology of drugs acting on specific systems/organs in the body.
Learning Objectives
After the completion of this course, student will be able to:
• Define various terms used in Pharmacology and enumerate drug nomenclature
with example;
• Describe common sources of drugs;
• Describe routes of drug administration with their advantages and disadvantages;
• Describe various processes (parameters) of pharmacokinetics;
• Describe the concept of pharmacodynamics including principle of drugs' action,
mechanism of action, dose-response relationship and therapeutic index;
• Mention the clinical importance and indication of Therapeutic Drug
Monitoring;
• Describe combined effect of drugs. Describe factors affecting drug response and
various adverse drug reaction and its clinical significance;
• Classification of cholinergic receptor agonists and muscarinic receptor
antagonists and adrenergic receptor agonists and its antagonists;
• Classify non-steroidal anti-inflammatory drugs (NSAIDs). Explain mechanism
of action, indications and adverse effects of commonly used NSAID, Newer
anti-inflammatory agent (monoclonal antibodies);
• Classify drugs used in rheumatoid arthritis, Gout, Skeletal muscle relaxant;
• Classify Antihypertensive drugs explaining mechanism of action, indications
and adverse effects of prototype drugs: ACE inhibitors, Calcium channel
blockers;
• Classification of Anti-arrhythmic Drugs and antihyperlipidemic drugs;
• Classify antianginal drugs. Explain mechanism of action, uses and adverse
effects of nitrates;
• Enlist the drugs used in treatment of cardiac failure and explain the mechanism
of action, uses and adverse effects of digoxin;
• Explain the mechanism of action, indication and adverse effect of commonly
used drugs in respiratory diseases;
• Classify antihistamines and explain the mechanism of action, indication and
adverse effect of commonly used drug;
• List drugs used in cough;
• Enlist the first line and second line anti-tubercular drugs. Explain common
adverse effects of first line antitubercular drugs;
• Describe general and local anesthetic drugs, and its classification;
• Describe sedatives and hypnotics: - mechanism of action, indications and
adverse effects of Phenobarbitone and Diazepam;
• Describe anti-epileptic drugs and explain mechanism of action, indications and
adverse effects of Phenytoin and sodium valproate;
• Describe drugs used in Parkinsonism;
• Explaining rationale of combining L-Dopa and Carbidopa;
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• Describe opioid analgesics. Explain mechanism of action, indications, adverse
effects and contraindications of morphine. Describe opioid agonist- antagonist
drugs;
• Describe principles of antimicrobial, antiviral Antifungal drugs: classification,
antimicrobial resistance and superinfection; and
• Explain mechanism of action, indications and adverse effects of commonly used
anti-microbials.
Course Contents
29
Classification of skeletal muscle relaxants with examples: centrally acting and peripherally
acting; Uses and adverse effects of centrally acting skeletal muscle relaxants; Uses of
peripherally acting skeletal muscle relaxants
E. Adrenergic Drugs 1 hour
Adrenergic receptors – types, distribution and effects, Common therapeutic uses
F. Adrenergic receptor antagonists 1 hour
Alpha blockers: examples, common uses; Beta blockers: examples and actions on CVS,
bronchi; important uses and adverse effect
30
Unit X: Respiratory System
A. Drugs used in Bronchial Asthma 1 hour
Examples of commonly used drugs their mechanism of action and adverse effects
B. Drugs used in Cough 1 hour
Classification of drugs with examples; Definition of: Mucolytics, expectorants, antitussives
C. Antihistaminics 1 hour
Classification of antihistamines (H1) with examples; Advantages and limitations of second
generation over first generation; Uses and adverse effects of H1 antihistamines
31
Teaching Methods
Lecture, demonstration and group discussion
References
1. Whalen K. Lippincott Pharmacology. 7th edition. Wolters Kluwer Health/Lippincott
Williams & Wilkins.
2. Tripathi KD. Essential of Medical Pharmacology. 8th edition. Jaypee Brothers Medical
Publishers.
3. Udaykumar P. Text book of Medical Pharmacology. 5th edition. New Delhi: CBS
Publishers & Distributors; 2016.
4. N.Murugesh. Concise Textbook of Pharmacology. 7th edition. Sathya Publishers; 2014.
5. Sadoskar RS, Rege NN, Bhandarkar SD. Pharmacolgy & Pharmacotherapeutics. 24th
edition. Elsevier; 2015.
32
BPT 156 Behavioral Science (Sociology and Psychology)
BPT, First Year, Second Semester
Course Description
This course will enable student to specific psychological factors and effects in physical illness
and helps in holistic approach in dealing with patients during the assessment, rehabilitation and
discharge. Behavioral and social sciences will assist physiotherapists in building therapeutic
relationships with their patients and increase the likelihood of following the advice.
Learning Objectives
After the completion of this course, student will be able to:
• Understand the basics of sociology;
• Define socialization and its types;
• Describe social processes and the influence of social process on disease and
physiotherapy;
• Explain family, community and marriage;
• Define culture and its impact on human behavior;
• Describe social stratification and social change;
• Identify types of community and health hazards in context of Nepal;
• Define, identify the role of social worker and social group;
• Define psychology and explain the scope and methods of psychology;
• Describe learning, emotions, memory, intelligence, personality, mental conflict and
frustration and explain the various principles, stages and factors affecting it;
• Explain concept, principle and various stages of life span development (developmental
psychology);
• Define types and determinants of attention and perception; and
• Explain various theories of motivation.
Course Contents
Section A: Sociology
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Unit IV: Family 2 hours
Definitions & types; Influence of family on human personality; Role of family in health and
disease; Family and nutrition & The effects of sickness in the family and psychosomatic disease
and their importance to physiotherapy.
Section B: Psychology
34
Unit III: Learning 2 hours
Definition & Principles of learning; Factors affecting leaning; Learning theories: classical
conditioning, Operant conditioning, insight learning, social learning theory & Effective ways
of learning: Massed/Spaced, Whole/Part, Recitation/Reading, Serial/Free recall,
Incidental/Intentional learning.
35
References
Sociology
1. Neeraja KP. Textbook of Sociology for Physiotherapy Students. Jaypee Brothers
Medical Publishers; 2008.
2. Bid D. Sociology for Physiotherapist. Jaypee Brothers Medical Publishers; 2006.
3. Sachdeva DR,Bhushan V. An Introduction to Sociology. Kitab Mahal.
4. Indrani TK, Textbook of Sociology for Graduates Nurses and Physiotherapy Students,
Jaypee Brothers Medical Publishers.
Psychology
1. Probst M, Skjaerven LH. Physiotherapy in Mental Health and Psychiatry. Elsevier.
2. Feldman RH. Understanding Psychology. 10th edition. New Delhi: Tata McGraw hill;
2017.
3. Morgan CT, King RA, Weisz JR, Schopler J. Introduction to Psychology. New Delhi:
Tata McGraw hill; 2004.
36
BPT 191 Laboratory 2 (Anatomy III and physiology II)
BPT, First Year, Second Semester
Course Description
The course is designed to provide practical aspect of anatomy and physiology knowledge about
cardiopulmonary, abdomen and its lymphatics, endocrine system, reproductive system and
excretory system.
Learning Objectives
Upon successful completion of the course, the student will be able to:
• Practically demonstrate the cardiopulmonary and cardiovascular structures,
functions, muscles, ligament, bones, joints, nerves and circulation;
• Practically demonstrate the abdominal structures, their nerve supply, lymphatics
and blood supply; and
• Practically demonstrate the structures of endocrine system, reproductive system and
excretory system.
Course Contents
Teaching Methods
Practical, demonstration, practical log book, and group discussion
References
1. Snell, R. S. Clinical Anatomy for Medical Students. Boston: Little Brown; 1995.
2. Chaurasia BD. Human Anatomy – Regional and Applied. Vol. 1 (Upper limb and
Thorax). 6th ed. New Delhi: CBS Publishers and Distributors; 2013.
37
3. Chaurasia BD. Human Anatomy – Regional and Applied. Vol. 2 (Lower limb,
Abdomen and Pelvis). 6th ed. New Delhi: CBS Publishers and Distributors; 2013.
4. Moore KL. Dalley AF. Agur AMR. Clinically Oriented Anatomy. 7h ed. Philadelphia:
Wolters Kluwer Health/Lippincott Williams & Wilkins; 2014.
5. Datta AK, Essentials of human Anatomy: Thorax and Abdomen. 5th ed. Current Books
International: Kolkata.
6. Singh I. Text book of Anatomy with colour atlas: Introduction, Osteology, Upper
Extremity, Lower Extremity. Vol I. New Delhi: Jaypee Brothers; 1996.
7. Singh I. Textbook of Human Osteology. 4th ed. New Delhi: Jaypee Brothers.
8. Standring S, Neil RB and Henry G. Gray's Anatomy: The Anatomical Basis of Clinical
Practice. 40th ed. Edinburgh: Churchill Livingstone/Elsevier; 2008.
9. Poddar S. Bhagat A. Handbook of osteology. 13 ed. Scientific Book Company. 2015.
10. Ghai CL. A Textbook of Practical Physiology. 8th ed. Jaypee Brothers.
11. Guyton AC, Hall JE. Text book of medical physiology. 12th ed. USA: Saunders
Elsevier; 2011.
12. Chaudhuri S K. Concise medical physiology. 6th ed. NCBA.
13. John NA. CC. Chatterjee’s Human Physiology. 12th ed. CBS Publishers and
Distributors.
14. Sembulingam K, Sembulingam P. Essentials of Medical Physiology. 5th ed. Jaypee
Brothers Medical Publishers; 2010.
15. Jain AK. Textbook of Physiology. Vol 1 & 2. 7th ed. Avichal Publishing Company;
2017.
16. Venkatesh D & Sudhakar H H. Basics of Medical physiology. 4th ed. Wolters Kluwer.
38
BPT 192 Practical 2 (Biomechanics I: Basic Concepts, Upper Extremity, Thorax &
Chest Walls)
BPT, First Year, Second Semester
Course Description
The course is designed to provide practical knowledge about basic concepts in biomechanics.
The course will also cover the practical aspect of biomechanics related to upper extremity and
thorax.
Learning Objectives
At the completion of this course, students should be able to:
Practically demonstrate the kinematics of the joint and levers in the human body with
an example each;
Practically demonstrate the kinematics and kinetics of shoulder complex, elbow joint
and wrist and hand; and
Practically explain the pathomechanics with at least one example of the shoulder
complex, elbow joint, and wrist and hand complex.
Course Contents
Teaching Methods
Practical, demonstration and group discussion
References
1. Levangie PK, Norkin C. Joint structure and function: a comprehensive analysis, 5th ed.
FA Davis Company.
2. Brunnstrom. Clinical Kinesiology. 5th edi. Bangalore: Jaypee Brothers Medical
Publishers. Bangalore; 1996.
3. Lippert LS. Clinical Kinesiology for Physical Therapist Assistants. 2nd ed. Bangalore:
FA Davis Company; 1994.
39
BPT 193 Practical 3 (Emergency Handling and First Aid)
BPT, First Year, Second Semester
Course Description
The aim of this course is to introduce to students to the principles and aims of first aid. It also
enables the student to be able to identify the injury or nature of illness affecting a casualty and
learn to assess the situation and summon appropriate help. This course is designed to enable
the students to give early, appropriate and adequate first aid in sensible order of priority. The
aim of this course is also to teach proper handling and arrangement for removal/transport of
casualty to hospital or to other health sectors in various situations. During this course the
students will also learn to make and pass on a report, and give further help if required.
Learning Objectives
On completion of this course, the students will be able to:
• Practice first aid in any emergency situation;
• Practically demonstrate the resuscitation technique;
• Practically manage injuries related to musculoskeletal injuries;
• Assess the casualty;
• Identify disorders of consciousness;
• Understand types of poisoning;
• Practically demonstrate basics of handling and transport; and
• Practically demonstrate different types of bandaging and their application.
Course Contents
40
Manual lifts and carries; Stretchers; Preparing a stretcher & Carrying a stretcher.
Teaching Methods
Lectures, Seminar, practical (model)
References
1. Bickley, L. S. Bates' Guide to Physical Examination and History Taking. 11th ed.
Philadelphia: Lippincott Williams & Wilkins; 2012.
2. Singh A, Shrestha K. A Textbook of Fundamental of Nursing. HLMC. 2017.
3. Suddarth B. Textbook of medical surgical nursing. 8th edition. Philadelphia: JB
Lippincott Co.
4. Craven RF, Hirnle CJ. Fundamentals of nursing: human health function, 3rd edition.
Sydney: JB Lippincott.
41