Seat No.: _____ Enrolment No.
_____________
GUJARAT TECHNOLOGICAL UNIVERSITY
[Link] - SEMESTER–2 EXAMINATION – WINTER-2019
Subject Code: MPL201T Date: 02/12/2019
Subject Name: Advanced Pharmacology II
Time: 02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Classify anthelminthic agents. Write a short note on pharmacology of 06
Albendazole.
(b) Describe the pharmacology of Amphotericin B. 05
(c) Classify Penicillins. Describe the Pharmacology of Ampicillin. 05
Q.2 (a) Explain structure, pharmacological actions and enlist different preparations of 06
insulin.
(b) Write a short note on glucocorticoids. 05
(c) Write a note on oral contraceptives. 05
Q.3 (a) Write in detail about mechanism of action, therapeutic uses and adverse 06
effects of Tetracycline.
(b) Classify anticancer drugs. Write in detail about paclitaxel. 05
(c) Describe the mechanism of action, adverse effects and uses of 05
aminoglycosides.
Q.4 (a) Classify antimalarial drugs. Describe the mechanism of action and adverse 06
effects of Chloroquine.
(b) Write a note antisecretory agents used in treatment of peptic ulcer. 05
(c) Describe the mechanism of action, adverse effects and uses of rifampicin 05
Q.5 (a) Write a note on recent Advances in treatment of Alzheimer’s disease. 06
(b) Write a note on Chronopharmacology 05
(c) Write a note on antidiarrheal agents 05
Q. 6 (a) Explain in detail about mechanism of action and therapeutic uses of 06
quinolones.
(b) Write a short note on antiretroviral drugs. 05
(c) Write a note on anti asthamatic drugs 05
Q.7 (a) Classify immunosuppresants. Write mechanism of action and adverse effects 06
of cyclosporine.
(b) Write a short note on anti-emetics. 05
(c) Write role of role of free radicals in various disease 05
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Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
- SEMESTER- II . EXAMINATION - SUMMER- 2018
[Link]
Subject Code:MPL20lT Date: 14/05/2018
Subject Name: ADVANCE PHARMACOLOGY II
Time: L0:304M TO 01:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks. l
Q"l (a) Explain the various stages of Alzheimer's disease. 06
(b) Explain DOTs therapy in TB" 05
(c) Classifu the antimicrobial agents according to their mechanism of actions. 05
Q.2 (a) What is chronopharmacology. Explain the significance of chronopharmacology 06
in cardiac diseases.
(b) Explain biosynthesis of thyroid hormones. 05
(c) Enlist the biochemical mediators involve in inflammation. Explain triple 05
response of infl ammation.
Q.3 (a) Discuss resistance of antimicrobial agents. 06
(b) Write a note on Macrolide antibiotics. 05
(c) Classify the Antiulcer drugs., Explain the MAO and side efl"ects of H-2 05
antagonist drugs.
Q.4 (a) Explain the advance pharmacological trehtment of Parkinson's disease. 06
(b) Write paracrine and autocrine regulation of hormone. 05
(c) What is Irrrmunopharmacology. Explain the role of immunosuppressant agents 05
in organ transplantation.
Q.5 (u) Classify oral hypoglycemic agents. Explain MOA, uses and side effects of 06
sulfonylureas.
(b) Explain the anti-viral drug action according to viral life cycle. {r5
(c) Explain the drug used in COPD. 05
Q. 6 (a) Enlist the human sex hormones. Explain the role of Estrogen and Progesterone 06
in female menstrual cycle.
(b) Classi$' anti-cancer drugs according to cell cycle. Explain MOA, uses and side 05
effects of 5- fluorouracil.
(c) Classify the hypersensitivity rgactions. Explain molecular mechanism of 05
delayed h1'persensitivity (type 4) reaction.
Q.7 (a) Write a brief note on drugs affecting calcium regulation. 06
(b) Write short note on antiemetic agents. 05
(c) What are the side effects and potential harms of HGH? 05
* ***{< **** ******
Seat No.: ________ Enrolment No.______________
GUJARAT TECHNOLOGICAL UNIVERSITY
[Link] – SEMESTER -2 - EXAMINATION –WINTER - 2018
Subject Code: MPL201T Date: 15/11/2018
Subject Name: Advanced Pharmacology II
Time :02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Describe uses and adverse effects of corticosteroids 06
(b) Justify use of folinic acid in the treatment of methotrexate toxicity. 05
(c) Classify Penicillins. Describe the Pharmacology of Ampicillin. 05
Q.2 (a) Enlist various hormone antagonists used in cancer chemotherapy. Write a note 06
on tamoxifen.
(b) Write a note on oral contraceptives 05
(c) Write a short note on imidazole derivatives used in treatment of amoebiasis. 05
Q.3 (a) Write in detail about mechanism of action, therapeutic uses and adverse effects 06
of Tetracycline.
(b) Write a note on Prokinetics agents 05
(c) Write a note on ketoconazole. 05
Q.4 (a) Write a note on proton pump inhibiters 06
(b) Justify following : 05
(i) Mesna is given with cyclophosphamide.
(ii) Pyridoxine is given with isoniazide.
(c) Explain in brief about pharmacotherapy of tuberculosis. 05
Q.5 (a) Write a note on recent Advances in treatment of Alzheimer’s disease. 06
(b) Classify antimalarials. Write a note on artemisinin. 05
(c) Write a note on antidiarrheal agents 05
Q. 6 (a) Write a note on recent Advances in treatment of Parkinson’s disease. 06
(b) What are HAART regimens? Write a note on zidovudine. 05
(c) Write a note on anti asthamatic drugs 05
Q.7 (a) Write a note on recent Advances in treatment of Diabetes mellitus. 06
(b) Enlist immunosuppressants. Write a note on cyclosporin. 05
(c) Explain mechanism of action, therapeutic uses and adverse effects of 05
aminoglycosides.
***************
Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
M. Ph. / - SEMESTER – II EXAMINATION – WINTER- 2021
Subject Code: MPL201T Date: 15/02/2022
Subject Name: Advanced Pharmacology - II
Time: 10:30 AM to 1:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Classify antitubercular drugs. Write a note on Rifampin. 06
(b) Explain with examples the various mechanisms involved in development of 05
resistance to antimicrobial agents.
(c) Classify antiviral agents. Discuss the adverse effects and uses of antiretroviral 05
agents.
Q.2 (a) Discuss the regulation of thyroid hormone and outline the mechanism of action 06
of anti-thyroid drugs.
(b) Discuss the pharmacological actions and adverse effects of Insulin. 05
(c) Write a note on oral contraceptives. 05
Q.3 (a) Classify oral hypoglycemic agents and discuss the role of DPP-IV inhibitors in 06
therapy of Diabetes.
(b) Explain the mechanism of action of Penicillins. Discuss their adverse effects and 05
its management.
(c) Write a note on Immunostimulants. 05
Q.4 (a) Classify the drugs used in cancer. Discuss the adverse effects of chemotherapeutic 06
agents and its management.
(b) Discuss in detail the role of corticosteroids in the management of Asthma. 05
(c) Classify drugs used for treatment of malaria. Discuss in brief the management of 05
Falciparum malaria.
Q.5 (a) Explain the mechanism of action: any three 06
1. Canaglifozin 2. Tacrolimus 3. Infliximab 4. Favipiravir
(b) Discuss the management of stress induced Ulcer. 05
(c) Classify antiemetics. Discuss pharmacology of Ondansetron. 05
Q. 6 (a) Discuss in brief applications of chronotherapy in Angina pectoris and Diabetes. 06
(b) Classify purgatives. Discuss the role of osmotic and bulk purgatives in chronic 05
constipation.
(c) Discuss the rationale for use of: any two 05
1. N-acetylcysteine for acetaminophen toxicity
2. Amifostine as adjunct with chemotherapy
3. Pyridoxine with Isoniazid
Q.7 (a) Highlight recent advances in the treatment of Alzheimer’s disease. 06
(b) Discuss the role of free radicals in pathophysiology of parkinson’s disease. 05
(c) Discuss in brief the management of Ulcerative Colitis. 05
***************
Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
M. Pharm - SEMESTER–II • EXAMINATION – SUMMER 2021
Subject Code: MPL201T Date: 06/09/2021
Subject Name: Advanced Pharmcology II
Time: 10.30 AM TO 01.30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Classify Oral hypoglycemic agents. Discuss pharmacology of Sitagliptin. 06
(b) Describe mechanism action and adverse effects of Quinolones. Discuss role of 05
Levofloxacin in treatment of Tuberculosis.
(c) Classify anticancer drugs. Describe pharmacology of methotrexate. 05
Q.2 (a) Write a note on pharmacology of anti-thyroid drugs. 06
(b) Discuss objectives and risk factors of combined use of antimicrobials. 05
(c) Classify Cephalosporins. Write brief note on cefuroxime. 05
Q.3 (a) Write a note on pharmacotherapy of asthma. 06
(b) Classify Drugs used to treat Peptic Ulcer. Describe pharmacokinetic aspect of 05
Omeprazole.
(c) Discuss protective activity of Coenzyme Q10 as antioxidant. 05
Q.4 (a) Describe pharmacology of corticosteroids. 06
(b) Classify antifungal drugs. Write mechanism of action and therapeutic use 05
Itraconazole.
(c) Write a note on role of free radical scavengers in treatment of Parkinson’s 05
disease.
Q.5 (a) Enumerate anti herpes virus drugs. Discuss pharmacology of acyclovir. 06
(b) Write a note on mediators of inflammation. 05
(c) Classify drugs used to treat constipation. Add a note on osmotic purgatives. 05
Q. 6 (a) Classify Anti Tuberculosis drugs. Describe DOT therapy. 06
(b) Write a note on role of oxidative stress in etiopathology of diabetes. 05
(c) Write a note on oral contraceptives. 05
Q.7 (a) Write a note on Immunosuppressants. 06
(b) Explain application of chronotherapy in asthma. 05
(c) Classify antiemetics. Write a note on pharmacology of Ondansetrone. 05
***************
Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
M. PHARM. - SEMESTER–II • EXAMINATION – WINTER -2022
Subject Code: MPL201T Date:14/12/2022
Subject Name: Advanced Pharmacology-II
Time: 10:30am to 01:30pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
[Link]. - SEM– II • EXAMINATION – SUMMER -2022
Subject Code: MPL201T Date: 14/07/2022
Subject Name: Advanced Pharmacology II
Time: 10:30AM TO 1:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Describe biochemical mechanisms of resistance to antibiotics with suitable 06
examples.
(b) Explain recent advances in treatment of parkinsonism disease. 05
(c) Write a note on drugs affecting calcium regulation. 05
Q.2 (a) Classify drug used for the treatment of helminthiasis. Explain pharmacology of 06
Ivermectin.
(b) Describe in brief application of chronotherapy in cardiovascular diseases. 05
(c) Explain the protective role of Coenzyme Q10. 05
Q.3 (a) What are Prokinetics? Explain pharmacology of bulk forming laxative and anti- 06
mobility agents.
(b) Explain advances in pharmacological treatment of Alzheimer’s disease. 05
(c) Write a note on cytoprotective drugs. 05
Q.4 (a) Justify: 06
1) Folinic acid is used in methotrexate toxicity.
2) Pyridoxine is given with isoniazid.
(b) Write actions of thyroid hormones and explain drugs used to treat 05
hyperthyroidism.
(c) Explain the role of immunosuppressant during organ transplantation. 05
Q.5 (a) Explain the role of free radicals in etiopathology of neurodegenerative diseases. 06
(b) Classify antiviral drugs according to their cellular and molecular mechanism. 05
(c) Write a note on pharmacotherapy of COPD. 05
Q. 6 (a) Classify oral hypoglycemic agents. Discuss pharmacology of SGLT2 06
inhibitors.
(b) Write mechanism of action and mechanism of resistance of aminoglycosides. 05
(c) Write a note on oral contraceptives. 05
Q.7 (a) Describe cellular and biochemical mediators involved in inflammation. 06
(b) Describe briefly various anticancer drugs according to their mechanisms of 05
action.
(c) Classify anti emetic drugs and describe pharmacology of D2 antagonists. 05
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