STUDY SYLLABUS & SCHEDULE

Pharmaceutical Sciences (25%)

1. Pharmaceutics & Drug Delivery Systems
A. Solids and Solid Dosage Forms
B. Solutions and Solubility
C. Surface Chemistry Dispersed Dosage Form
o Emulsions
o Suspensions
o Surface Chemistry
D. Drug Stability
E. Pulmonary Drug Delivery
F. Dermal and Transdermal Drug Delivery
G. Parenteral Drug Delivery
H. Ophthalmic, Otic, Nasal Drug Delivery
I. Rectal and Vaginal Drug Delivery
J. New Drug Delivery Systems
o Controlled/Targeted Delivery
o Protein Drug Delivery
K. Good Manufacturing Practices
L. Product Quality Control and Risk Management
M. Pharmaceutical Analysis

2. Pharmacokinetics & Biopharmaceutics

A. Compartments
B. Absorption
C. Distribution and Protein Binding
D. Elimination and Clearance Concepts
E. Kinetics of Intravenous Drugs
 F. Kinetics of Doses
G. Non-Linear Pharmacokinetics
H. Bioavailability and Bioequivalence
I. Clinical Application of Pharmacokinetics
J. Examples of Pharmacokinetic Calculations

3. Pharmacology
A. General Principle of Pharmacology
o Drug Absorption
o Disposition
o Biotransformation
o Elimination
B. Receptors
C. Autonomic Pharmacology
D. Anaesthetics
E. Pharmacology of Inflammation
F. CNS Pharmacology
G. Drugs Affecting the Haematopoietic System
H. CVS Pharmacology
I. Hemostasis And Thrombosis
J. Drugs for Dyslipidemia
K. Diuretics
L. Cancer Chemotherapy
M. GIT Pharmacology
N. Endocrine Pharmacology
O. Anti-Infective Agents
P. Respiratory Drugs
Q. Ophthalmic Drugs
R. Drugs of Abuse
4. Toxicology
A. Introduction to Toxicology
B. Mechanisms of Toxicology
C. Modulators of Chemical Toxicology
D. Toxicological Evaluation
E. Clinical Teratogenesis
F. Carcinogenesis/Mutagenesis
G. Immunological Toxicology
H. Chemicals and Environmental Toxins
o Alcohols, Glycols, Aldehydes, Nitrates and Nitrites, Sulfides, Hydrocarbons
o Carbon Monoxide, Cyanide
o Pesticides
o Metals
o Corrosives
o Plants
o Warfare Chemical Weapons
I. Drug Toxicity
o Analgesics and Anti-Inflammatory Drugs
o Opioids
o CNS Stimulants and Depression, Antidepressants, Hallucinogens
o Anticholinergics
o Cardiovascular Drugs
o Vitamins

5. Biotechnology and Pharmacogenetics

A. Introduction to Biotechnology
B. Recombinant DNA Technology and Production of Protein Drugs
C. Industrial Production of Protein Drugs
 D. Biotechnology related Techniques
E. Transgenic Animals
F. Gene Therapy
G. Pharmacogenomics and Genotyped Prescribing
H. Antisense Oligonucleotide Therapy
I. Small Interfering RNA
J. Immunology: Overview of the Immune System
K. Monoclonal Antibodies
L. Vaccine: Biotechnology Approaches
M. Cytokines
N. Erythropoietin
O. Thrombolytic Agents
P. Formulation of Proteins and Peptide Drugs

Pharmacy Practice (55%)

1. Pathophysiology
A. Cell Injury and Death
B. Genetics
C. Fluid and Electrolyte Disorders
D. Inflammation
E. Immunopathology
F. Obstructive Lung Disease
G. Gastrointestinal Disease
H. Liver Disease
I. Renal Disease
J. Endocrine Disorders
K. Cardiovascular Disorders
L. Haematology
 M. Neurology
N. Psychiatry
O. Carcinogenesis and Neoplasia

2. Clinical Biochemistry / Laboratory and Diagnostic Testing

A. Routine Hematology
B. Hematologic Diagnostic Tests
C. Electrolyte and Blood Chemistry
D. Liver Biochemistry
E. Bone Metabolism
F. Bone Metabolism
G. Renal Function and Disorders
H. Estimation of Glomerular Filtration Rate and Renal Blood Flow
I. Gastrointestinal Tract Tests
J. Pulmonary Function Tests
K. Neurology
L. Cardiovascular Diagnostic Tests
M. Neoplasm Screening
N. Endocrinology
O. Infectious Disease / Immunologic / Rheumatologic / Other Tests
P. Laboratory Aspects of Antimicrobial Agents

3. Pharmacotherapeutics
A. Basic Principles
B. Respiratory Diseases
C. Dermatology
D. Eye, Ear, Nose and Throat
E. Gastroenterology
F. Cardiovascular Diseases
 G. Genitourinary Disease
H. Musculoskeletal Disease
I. Gynecology
J. Infectious Diseases
K. Neurology
L. Endocrinology
M. Psychiatry
N. Nephrology
O. Other

4. Patient Care Process

A. Assessment
B. Care Plan
C. Follow-up Evaluation
D. Documentation

5. Special Population
A. Neonates
B. Pediatrics
C. Geriatrics
D. Pregnant Women
E. Lactating Women

6. Nutrition
A. Digestion
B. Function
C. Dietary Requirement & Canada’s Food Guide
D. Assessment of Nutritional Status
E. Malnutrition and Effects on Health
 F. Metabolism and Transport of nutrients
G. Regulations of Blood Glucose
H. Weight Management and Eating Disorder

7. Prescription Processing and Product Preparation

A. Interpretation
B. Application of Legislative Requirements
C. Sterile Compounding
D. Handling of Hazardous Drugs
E. Cold Chain Management
F. Checking Process for Dispensing Prescription

8. Prescription Calculation
A. Systems and Unit of Measure
B. Dosage Calculations
C. Compounding Calculations
D. Dosing Calculations for Parenteral Medications
E. Prescription Processing Calculations

9. Medication Administration

10. Communication / Patient Counselling

A. Pharmacist Interaction in the Workplace
B. Development of Effective Communication Skills
C. Patient Counselling and Education on Prescription Medications
D. Patient. Counselling and Education for Administration of Various Dosage Forms
E. Patient Counselling and Education to Promote Adherence to Regimens and
Therapy
F. Patient Counselling and Education on Diagnostic/Monitoring Tools
 G. Patient Counselling and Education on non-Prescription Medicines
H. Patient Counselling and Education on non-Prescription Medications
I. Patient Counselling and Education on “no Public Access” Medications
J. Patient Counselling and Education on Herbal and Complementary Therapies
K. Patient Counselling and Education on Home Health Care

11. Collaborative Care

Behavioural, Social and Administrative Pharmacy Sciences (20%)

1. Health Promotion and Disease Prevention

A. Development of Health Promotion Strategies
B. Public Health Agency of Canada
C. Preventive Health Services (e.g., Immunization, Tobacco Cessation Counselling)

2. Pharmacy Management
A. Basic Responsibilities of Management
o Classical Function of Management
o Entrepreneurship
o Components of the Business Plan
o Workplace Safety
B. Marketing Management in Pharmacy
C. Human Resource Management in Pharmacy
D. Financial Management in Pharmacy
E. Community Pharmacy Management
F. Hospital Pharmacy Management

3. Literature Evaluation / Research Methods / Evidence-Based Decision-Making

 A. Evaluation of Drug Literature and Scientific Information
B. Research Methods
o Design
o Measures
o Validity
o Diagnostic Testing

4. Medication / Patient Safety Practices

A. Policies and Procedures
B. Canada Vigilance Program
C. Health Canada MedEffect
D. Development of Strategies and Actions
E. Identification, Management and Documentation of Medication Incidents
F. Institute for Safe Medication Practices (ISMP)
G. Medication Reconciliation
H. Canadian Patient Safety Institutes (CPSI)

5. Professionalism / Ethics
A. Ethical Principles
B. Patient Consent and Decision Making
C. Confidentiality and Privacy
D. Continuity of Care
E. Advocacy for the Patient
F. Conflict between the Pharmacist and other Health-care Providers
G. Respect for Life and the Autonomy of Patients
H. Respecting of Professional Boundaries
I. Pharmacist Conscientious Objection (Right to Refuse)
J. Other Issues in Pharmacy and Health Care Ethics
K. Professionalism
6. Canadian Health Care Systems (CHCS)
A. Governance and Standards
B. The Pharmaceutical Industry and Related Agencies
C. Contemporary Issues in CHCS
D. Pharmacy Law and Regulation of the Profession
E. Scientific and Humanistic Approaches to Modern (Western) Medicine and
Pharmacotherapy
F. Hospital Pharmacy Practice Development
G. Community Pharmacy Practice