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Key GI Hormones and Their Functions

The document outlines various hormones involved in gastrointestinal functions, detailing their sites of secretion, stimuli for release, and actions. Key hormones include Gastrin, Secretin, Gastric Inhibitory Peptide, Cholecystokinin, and Motilin, each with specific roles in digestion and metabolism. The document emphasizes the complex interactions between these hormones and their effects on processes such as secretion, motility, and growth in the digestive system.

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47 views1 page

Key GI Hormones and Their Functions

The document outlines various hormones involved in gastrointestinal functions, detailing their sites of secretion, stimuli for release, and actions. Key hormones include Gastrin, Secretin, Gastric Inhibitory Peptide, Cholecystokinin, and Motilin, each with specific roles in digestion and metabolism. The document emphasizes the complex interactions between these hormones and their effects on processes such as secretion, motility, and growth in the digestive system.

Uploaded by

x7csck7pqg
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Hormone Site Stimulus Action

Gastrin
Protein
++HCl & pepsin secretion
G-17 (90%) G cells of Distention
G-34 (10%) antrum, Vagus (gastrin releasing ++Mucosal growth
upper small polypeptide). ++LES Contraction
Can’t be inhibited by intestine. ++Gastric motility
atropine because its (Acid inhibits release).
work on Ach only
++Pancreatic HCO3 secretion
Secritin S cells of ++Biliary HCO3 secretion
Acid
upper small ++Growth of exocrine pancreas
The first GI hormone Fat
intestine. ++Pepsin secretion
was observed.
--Gastrin release& HCl secretion
Gastric
inhibitory
peptide K cells of Protein ++Insulin release
or upper small Fat
intestine. CHO --HCl secretion
Glucose-
dependent
insulinotropic
++Gallbladder contraction
I cells of Acid ++Pancreatic enzyme secretion
Cholecystokinin upper small Protein ++Pancreatic HCO3 secretion
intestine. Fat ++Growth of exocrine pancreas
--Gastric emptying
M cells of Fat ++Gastric motility
Motilin upper small Acid
intestine. Nervous ++Intestinal motility

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