Assessment in Hemiplegic patients
De nition of stroke : Cerebrovascular accident (CVA) is the sudden
loss of neurological function caused by an interruption of blood ow to
the brain.
Types of stroke.
Ischemic stroke. Hemorrhagic stroke
Ishemic stroke: Ischemic stroke is the most common type , affecting
about 80% of individuals with stroke , and can be the result of a
thrombosis, embolism, or hypoperfusion.
Hemorrhagic stroke : Occurs when the blood vessels rupture causing
leakage of blood in or around the brain. Clinically , a variety of focal
de cits are possible, including changes in level of consciousness and
impairments of sensory, motor , cognitive, perceptual , and language
functions.
To be classi ed as stroke, neurological de cits are characterised by
paralysis (hemiplegia) or weakness (hemiparesis) , typically on the
side of the body opposite side of the lesion.
Hemiplegia : The term hemiplegia is often used generally to refer to
wide variety of motor problems that result from stroke. The location
and extent of brain injury, the amount of collateral blood ow, and
early acute care management determine the severity of neurological
de cits in an individual patient.
RISK FACTORS
Cardiovascular disease affecting the brain and heart share a number
of common risk factors important to the development of
atherosclerosis (build up fats, cholesterol & other substances in & on
the arteries walls).
Major risk factors for stroke are - hypertension, diabetes mellitus,
disorders of heart rhythm, high blood cholesterol, smoking/ tobacco
use & heart disease (HD).
PATHOPHYSIOLOGY:
- Sudden loss of O2 , glucose and cerebral blood ow deprivation.
- within minutes neutrons die within the ischemic core. While neurons
in the surrounding forming penumbra survive for slightly longer( for
penumbra to survive 20-25% blood ow should be present).
- Ischemia triggers a ischemic cascade. It causes neurotransmitters
to release glutamate and aspartate.
- This produces progressive disturbances of energy mechanisms and
anoxic depolarisation which results in an inability to produce ATP.
- It leads to excess in ux of calcium and pump failure of neuronal
membrane.
- Excess calcium reacts with intracellular phospholipids to form free
radicals.
- Calcium in ux also stimulates the release of nitric oxide and
cytokines . Both mechanisms further damage brain cell.