KEY POINT
u Introduction of Keshav
interchem
u Important of GMP & cGMP at
Glance
u Equipment’s use for
production
u Products and Raw material
u Utility & Waste Management
u Safety and Hazard condition
u Conclusion
Introduction of Keshav Interchem
History
Established in 2015 ,India Keshav Interchem has gained immense
expertise in supplying & trading of Chemical like di-methoxy
benzoic acid (Veratric acid) etc. The supplier company is located in
Ankleshwar, Gujarat and is one of the leading sellers of listed
products.
Introduction of Keshav Interchem
Name & Address Of The Project Site M/S. Keshav Interchem
Plot No. 905/11/8, GIDC Estate, Panoli-
394116, Taluka: Ankleshwar, District:
Bharuch, Gujarat
Address Of Correspondence M/S. Keshav Interchem
A-1/32, Nirman Complex, R. C. Technical
Road, Chankyapuri, Ghatlodia, Ahmadabad-
386001 (Guj.)
Total Cost Of Proposed Project Total Costs Of The Project Will Rs. 525 Lakhs.
Capital Cost Of Air & Water Pollution Control
System And Environmental Monitoring
Equipments Will Be Rs. 80 Lakhs.
Total Plot Area 2767.18 M2
Green Belt Area,/Tree Plantation Area 915 M2
Important of GMP & cGMP at Glance
GMP
GMP refers to the Good Manufacturing Practice Regulations
promulgated by the US Food and Drug Administration under the
authority of the Federal Food, Drug, and Cosmetic Act. These
regulations, which have the force of law, require that
manufacturers, processors, and packagers of drugs, medical
devices, some food, and blood take proactive steps to ensure that
their products are safe, pure, and effective. GMP regulations
require a quality approach to manufacturing, enabling companies
to minimize or eliminate instances of contamination, mixups, and
errors. This in turn, protects the consumer from purchasing a
product which is not effective or even dangerous.
Important of GMP & cGMP at Glance
CGMP
GMP is also sometimes referred to as "cGMP". The "c"
stands for "current" reminding manufacturers that they
must employ technologies and systems which are up-
to-date in order to comply with the regulation.
Systems and equipment used to prevent
contamination, mixups, and errors, which may have
been "top-of-the-line" 20 years ago, may be less than
adequate by today's standards.
Equipment’s use for production
Reactor Reactor Heat Exchenger
• GLR Accessories
• SSR • Gasket, Valve,
(shell & Tube
Agitator etc.. H.E.)
Agitated vessel Centrifuge
Equipment’s use for production
Type Of Reactor
GLR SSR
Equipment’s use for production
Reactor Accessories
Gasket Valve
Equipment’s
use for
production
Heat Exchenger(shell & Tube
H.E.)
Equipment’s
use for
production
Agitated vessel
Equipment’s
use for
production
Centrifuge
Products
and Raw
material
Veratric acid Pregabalin
Products and Raw material
Introduction
Veratric Acid Pregabalin
u Veratric acid, a phenolic compound u Pregabalin, a GABA analog, is a
with the chemical formula widely used medication for the
C9H10O4, is a valuable chemical treatment of neuropathic pain,
intermediate used in various epilepsy, and generalized anxiety
industries. Its unique structure and disorder. Its mechanism of action
properties make it a versatile involves binding to calcium
compound with applications in voltage-gated channels in the
pharmaceuticals, agrochemicals, brain, reducing the release of
and fine chemicals. neurotransmitters that contribute
to pain and anxiety.
Products and Raw material
Physical and chemical properties
Veratric acid Pregabalin
u Appearance: White to off-white u Appearance: White to off-white
crystalline powder crystalline powder
u Molecular weight: 182.17 g/mol u Molecular weight: 157.21 g/mol
u Melting point: 179-182 °C
u Melting point: 174-176°C
u Solubility: Soluble in water, ethanol,
u Solubility: Soluble in hot water, ethanol,
and methanol
and ether
u Stability: Stable under normal
u Stability: Stable under normal conditions, storage conditions
but sensitive to strong oxidizing agents
u Reactivity: Can undergo reactions
u Reactivity: Can undergo reactions such as such as esterification, amidation,
esterification, etherification, and oxidation and reduction
Utility & Waste Management
Water usage
Source of Water Supply GIDC Water Supply
Water consumption (KL/day)
Utility & Waste Management
Waste water generation (KL/day)
Utility & Waste Management
waste management
Utility & Waste Management
Flue gas emission
Utility & Waste Management
Hazardous waste
Safety and Hazard condition
Possible sources of hazard Types of hazards
• Handling and processing of • Electrical shock.
inflammable and combustible raw
materials • Injury and death
• Handling of compressed gases. • Fire.
• Handling and processing of toxic • Chemical burn.
substance • Infection.
• Handling of corrosive substances • Intoxication.
• Handling of oxidising substances
• Handling of dust-producing
equipment and also dust
• Handling of boiler
Safety and Hazard condition
Prevention of Accidents
Standard
Operating Safety Policy Monitoring
Procedure (SOP)
Preventive
Safety Audit Risk Analysis
Maintenance
Involvement of
Personnel
Conclusion
This is conducted at Keshav Intermediate ; panoli Gujarat
has given an overall view of the working of an
organization. It also helped us to understand the work
culture of the people there.
This has also helped us to improve our interface with the
industry, to know and actually realize the tasks and duties
involved in an industry.
Moreover this has really helped us to improve our
knowledge in the chemical field. For that we are really
thankful to this organization & its management.
Reference
u 1) Don W. Green, Robert H. Perry, Perry's Chemical Engineers' Handbook, 8th
Edition, McGrawHill, New York, 2008.
u 2) [Link]
u 3) [Link]
u 4) [Link]
Thank you
