YOU CALL THE SHOTS
Vaccine Administration:
Intramuscular (IM) Injection
Children 3 through 6 years of age
Administer these vaccines by IM injection:
Diphtheria, tetanus, and pertussis (DTaP) Diphtheria, tetanus, pertussis, polio, Influenza vaccine, inactivated (IIV)
Diphtheria, tetanus, pertussis, and polio Haemophilus Influenzae type b and Inactivated polio vaccine (IPV)*
(DTaP-IPV) hepatitis B (DTaP-IPV-Hib-HepB)
Meningococcal conjugate (MenACWY)
Diphtheria, tetanus, pertussis, polio, and Haemophilus Influenzae type b
Pneumococcal conjugate (PCV13)
hepatitis B (DTaP-IPV-HepB) Hepatitis A (HepA)
Pneumococcal polysaccharide (PPSV23)*
Diphtheria, tetanus, pertussis, polio, and Hepatitis B (HepB)
Haemophilus Influenzae type b (DTaP-IPV/Hib)
Note: Age, recommendations for use, and other indications vary by product. Always review manufacturers’ product information as well as the current immunization
schedule for children ([Link]/vaccines/schedules/hcp/imz/[Link]) before administering vaccine.
*May also be administered by subcutaneous injection.
To ensure vaccines are safe and effective, it’s important to prepare and administer them correctly:
Follow aseptic technique.
Use a new, separate needle and syringe for each injection.
Perform hand hygiene before vaccine preparation, between patients, when changing gloves (if worn), and any time hands
become soiled.†
†Gloves are not required unless the person administering the vaccine is likely to come in contact with potentially infectious body fluids or has open lesions on the hands.
If worn, perform hand hygiene and change gloves between patients.
1. Use the correct syringe and needle. 5/8 in (16mm) 1 in (25 mm)
Administer the vaccine using either a 1-mL or 3-mL syringe.
Use the correct gauge and needle length.‡ If the skin is stretched tightly
and the subcutaneous
22- to 25-gauge needle tissues are not bunched
5/8- to 1-inch (16 to 25 mm) needle
‡Use a 1- to 1.25-inch (25–32 mm) needle if administering vaccine in the vastus lateralis muscle in the anterolateral thigh.
2. Identify the injection site.
Preferred site: the deltoid muscle in the upper arm§
Use anatomical landmarks to determine the injection site. The deltoid muscle is Scapula
a large, rounded, triangular shape. Find the acromion process, which is the bony
point at the end of the shoulder. The injection site will be below the bone and Acromion
above the axillary fold/armpit. process Injection
§The vastus lateralis muscle in the anterolateral thigh can also be used. site
Deltoid
3. Administer the vaccine correctly.
muscle
Inject the vaccine into the middle and thickest part of the muscle. Insert the
needle at a 90-degree angle and inject all the vaccine in the muscle tissue. Axillary
Aspiration (i.e., pulling back on the plunger) is not necessary before injecting fold/
the vaccine. No large blood vessels are present at the recommended injection armpit
sites, and a process that includes aspiration might be more painful. Humerus
For more information, see [Link]/vaccines/hcp/acip-recs/general-recs/
[Link]
If administering more than one IM injection:
Use the vastus lateralis muscle in the anterolateral thigh for young children.
This muscle is preferred for young children because of its larger muscle mass.
Separate the injection sites by 1 inch if possible.
For additional information, go to CDC's clinical resources on vaccine administration
Advisory Committee on Immunization Practices General Best Practice Guidelines for Immunizations:
Vaccine Administration section at [Link]/vaccines/hcp/acip-recs/general-recs/[Link]
Vaccine administration resource library at [Link]/vaccines/hcp/admin/[Link]
11/01/2021 CS 322033-H