Human Reproductive System Overview
Human Reproductive System Overview
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E
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HUMAN
REPRODUCTION
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HUMAN REPRODUCTION
• Reproduction is the production
of young ones by an organism.
• Humans are sexually reproducing
and viviparous.
HUMAN REPRODUCTIVE
SYSTEM
MALE FEMALE
REPRODUCTIV REPRODUCTIV
E SYSTEM E SYSTEM
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MALE REPRODUCTIVE SYSTEM
Male reproductive system
Paired testes Rete testis
Vasa efferentia
Accessory
ducts Epididymis
Vas deferens
Accessory
Seminal vesicles (2)
glands
Cowper’s (bulbo-
External urethral) glands (2)
genitalia (Penis)
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MALE REPRODUCTIVE
SYSTEM
1. PAIRED TESTES
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MALE REPRODUCTIVE
SYSTEM
1. PAIRED TESTES
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MALE REPRODUCTIVE
SYSTEM
2. ACCESSORY DUCTS
Rete testis
Accessory ducts (Duct
(irregular cavities)
Vasa efferentia
system)
Epididymis
(stores sperms temporarily)
Vas deferens
Vas deferens joins with a duct of seminal vesicle to form common-ejaculatory duct.
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MALE REPRODUCTIVE
SYSTEM
2. ACCESSORY DUCTS
Rete testis
Vasa efferentia
Epididymis
Vas deferens
Urethra
The urethra receives the ducts of prostate and
Urethral meatus Cowper’s glands and passes through the penis.
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MALE REPRODUCTIVE
SYSTEM
3. ACCESSORY GLANDS
• They include
A pair of seminal vesicles.
A prostate gland.
A pair of Cowper’s (bulbo-
urethral) glands.
• Their collective secretion is called
seminal plasma. It is rich in
fructose, Ca and enzymes.
• It is a copulatory organ.
• It is made up of special
erectile spongy tissues.
• When spongy tissue is filled
with blood, the penis erects.
It facilitates insemination.
• The cone-shaped tip of the
penis is called glans penis. It
is covered by prepuce
(foreskin).
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?
CHECK YOUR GRASP
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Select the odd one from the following
?
A. Prostate
B. Cowper’s glands
C. Seminal vesicles
D. Epididymis
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Which is false statement?
?
A. Testes are the primary sex organ of male.
B. Sertoli cells give nourishment to developing
sperms.
C. Leydig cells produce androgen.
D. Rete testis temporarily stores sperms.
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Which gland lubricates the penis?
?
A. Cowper’s gland
B. Prostate gland
C. Seminal vesicle
D. All of the above
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The cone shaped tip of the penis is called
?
A. Vas deferens
B. Glans penis
C. Prepuce
D. Urethral meatus
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FEMALE REPRODUCTIVE HEALTH
Paired Oviducts
(Fallopian tube)-2
ovaries
reproductive
Uterus
Female
system
Vagina
Accessory
ducts Mons pubis
Vestibule
Hymen
External
genitalia Clitoris
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FEMALE REPRODUCTIVE
SYSTEM
1. PAIRED OVARIES
Ovary
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FEMALE REPRODUCTIVE
SYSTEM
1. PAIRED OVARIES
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FEMALE REPRODUCTIVE
SYSTEM
2. ACCESSORY DUCTS (DUCT SYSTEM)
2 OVIDUCTS
(FALLOPIAN TUBES)
VAGINA
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FEMALE REPRODUCTIVE
SYSTEM
2. ACCESSORY DUCTS (DUCT SYSTEM)
A. Oviducts (Fallopian tubes)
• Each oviduct is 10-12 cm long.
• It has 3 parts: Infundibulum,
Ampulla & Isthmus.
Infundibulum: Funnel-shaped
opening with many finger-like
fimbriae. It helps to collect the
ovum.
Ampulla: Wider part.
Isthmus: Narrow part. It joins the
uterus.
• The ciliated epithelium lined the
lumen of oviduct drives the ovum
towards the uterus.
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FEMALE REPRODUCTIVE
SYSTEM
2. ACCESSORY DUCTS (DUCT SYSTEM)
B. Uterus (womb)
• It is inverted pear shaped.
• It is supported by ligaments
attached to the pelvic wall.
• Uterus has 3 parts: Upper fundus,
middle body and terminal cervix.
• Cervix opens to vagina.
• The uterine wall has 3 layers:
Perimetrium: External thin
membrane.
Myometrium: Middle thick layer of
smooth muscle.
Endometrium: Inner glandular &
vascular.
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FEMALE REPRODUCTIVE
SYSTEM
2. ACCESSORY DUCTS (DUCT SYSTEM)
C. Vagina
• It opens to exterior between urethra and
anus.
• The lumen of vagina is lined by a
glycogen-rich mucous membrane
consisting of sensitive papillae and
Bartholin’s glands.
• The secretions of Bartholin’s glands
lubricate penis during sexual act.
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FEMALE REPRODUCTIVE 3. EXTERNAL GENITALIA
SYSTEM (VULVA/PUDENDUM)
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FEMALE REPRODUCTIVE 3. EXTERNAL GENITALIA
SYSTEM (VULVA/PUDENDUM)
C. Hymen (Maiden head)
• A membrane which partially cover
the vaginal opening. It is often torn
during the first coitus.
• It may also be broken by a sudden fall
Hymen may also be broken by a
or jolt, insertion
sudden of a vaginal
fall or jolt, insertiontampon,
of a
active participation
vaginal tampon, activein some sports
participation
in some
items etc.sports
In someitems etc. hymen
women, In some
women, hymen
persists even persists
after coitus.even
So theafter
coitus. So the hymen is not a reliable
hymen is not a reliable indicator of
indicator of virginity.
virginity.
D. Clitoris
• A highly sensitive organ lying just
in front of the urethral opening.
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FEMALE REPRODUCTIVE
SYSTEM
MAMMARY GLANDS (BREASTS)
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FEMALE REPRODUCTIVE
SYSTEM
MAMMARY GLANDS (BREASTS)
Sequence of milk
conduction
Mammar Mammar Mammar Mammar Lactifero
y alveoli y tubule y duct y ampulla us duct
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?
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Ovulation is
?
A. Formation of ovum in ovary.
B. Release of ovarian hormones.
C. Formation of ovarian follicles.
D. Release of ovum from ovary.
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The muscular layer of the uterus is
?
A. Perimetrium
B. Myometrium
C. Endometrium
D. Corpus luteum
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Which of the following organ is highly sensitive?
?
A. Clitoris
B. Bartholin’s gland
C. Hymen
D. Mons pubis
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Which is not a part of accessory ducts of female reproductive
system?
?
A. Infundibulum
B. Graafian follicles
C. Uterus
D. Vagina
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Several mammary ducts join to form
?
A. Lactiferous duct
B. Mammary tubules
C. Mammary ampulla
D. Mammary lobes
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GAMETOGENESIS
GAMETOGENESIS
SPERMATOGENESI
OOGENESIS
S
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GAMETOGENESIS 1. SPERMATOGENESIS
Spermatogonia (Sperm
Formation of
spermatids mother cells) produce
spermatids.
STAGES OF
SPERMATOGENESIS
Spermiogen Spermatids transform
esis into sperm
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GAMETOGENESIS 1. SPERMATOGENESIS
2n
2n 2n Spermatogonia (2n)
2n 2n 2n 2n Mitosis
Spermatozoa (n)
Spermiogenesis
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GAMETOGENESIS 1. SPERMATOGENESIS
• A primary spermatocyte → 2
secondary spermatocytes (n).
• A sec. spermatocyte → 2
spermatids (n).
Thus
A primary spermatocyte →
4 spermatids/4 sperms
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GAMETOGENESIS 1. SPERMATOGENESIS
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GAMETOGENESIS 2. OOGENESIS
• It is the formation and
maturation of ovum.
• It takes place in Graafian
follicles.
• Oogenesis is initiated in
embryonic stage when millions
of egg mother cells (oogonia)
are formed within each ovary.
• No more oogonia are formed and
added after birth.
• Oogonia multiply to form primary
oocytes. They enter into
prophase-I of the meiosis and
get temporarily arrested at that
stage.
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GAMETOGENESIS 2. OOGENESIS
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GAMETOGENESIS 2. OOGENESIS
Granulosa cells
Primary oocyte
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GAMETOGENESIS 2. OOGENESIS
• The primary oocyte within the tertiary
follicle grows in size and undergoes first
unequal meiotic division to form a large
haploid secondary oocyte and a tiny first
polar body. The secondary oocyte retains
the nutrient rich cytoplasm of the primary
oocyte.
• It is unknown that whether the first polar
body divides further or degenerates.
• The tertiary follicle further changes into the
mature follicle (Graafian follicle).
• Secondary oocyte forms a new membrane
(zona pellucida).
• Graafian follicle now ruptures to release the
secondary oocyte (ovum) from the ovary.
This is called ovulation.
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Oogenesis
GAMETOGENESIS 2. OOGENESIS
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GAMETOGENESIS Spermatogenesis v/s Oogenesis
Spermatogenesis Oogenesis
?
A. Spermiogenesis
B. Spermatogenesis
C. Spermiation
D. Gametogenesis
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Which of the following is/ are haploid?
?
A. Secondary
spermatocytes
B. Spermatids
C. Spermatozoa
D. All the above
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Number of spermatids formed from each primary spermatocyte is
?
A. 2
B. 4
C. 6
D. 8
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Head of the sperm is formed of
?
A. Nucleus and
mitochondria
B. Mitochondria and
acrosome
C. Nucleus and acrosome
D. Acrosome and centriole
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Number of primary follicles left in each ovary at puberty is about
?
A. 6 lakh to 8 lakh
B. 60,000 to 80,000
C. 6000 to 8000
D. 600 to 800 million
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During oogenesis the primary oocyte divides into
?
A. Haploid secondary oocyte and polar
body
B. Diploid secondary oocyte and polar
body
C. 2 haploid secondary oocytes
D. 2 diploid secondary oocytes
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The layer of ovum formed of follicle cells is
?
A. Oolemma
B. Vitelline membrane
C. Corona radiata
D. Zona pellucida
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MENSTRUAL CYCLE
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MENSTRUAL CYCLE (REPRODUCTIVE CYCLE)
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MENSTRUAL CYCLE (REPRODUCTIVE CYCLE)
Phases of
Menstrual Cycle
Menstrual phase:
1-5th day
Ovulatory phase:
14th day
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MENSTRUAL CYCLE II. Follicular (proliferative) phase
5-13th
• It starts from 5th day after day
menstruation and completed
within 8-12 days.
• In this phase, action of
gonadotropins (FSH &LH) from
pituitary occurs.
• FSH stimulates
New
Development of primary Endometrium
follicles into Graafian follicles.
Secretion of oestrogens by
Graafian follicles.
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MENSTRUAL CYCLE II. Follicular (proliferative) phase
5-13th
Oestrogens stimulate
day
Proliferation of ruptured
uterine endometrium and
mucus lining of oviduct &
vagina.
Development of secondary
sexual characters. New
Endometrium
Suppression of FSH secretion.
Secretion of LH (Luteinizing
hormone).
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MENSTRUAL CYCLE III. Ovulatory phase
14th
day
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MENSTRUAL CYCLE IV. Secretory (Luteal) phase
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MENSTRUAL CYCLE IV. Secretory (Luteal) phase
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MENSTRUAL CYCLE Overall changes
?
A. Menstrual cycle occurs only in primates.
B. During pregnancy menstrual cycle stops.
C. Follicular phase starts from 5th day after
menstruation.
D. Corpus albicans releases progesterone.
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After ovulation, Graafian follicle is transformed into
?
A. Corpus callosum
B. Corpus albicans
C. Corpus luteum
D. Corpora
quadrigemina
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Ovulation occurs on
?
B. 14th day of the cycle
C. 18th day of the cycle
D. None of these
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The first menstruation during puberty is known as
?
A. Menarche
B. Menopause
C. Metastasis
D. Meningitis
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FERTILIZATION &
IMPLANTATION
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FERTILIZATION AND IMPLANTATION
During copulation, semen is released by the penis into the vagina. It is called
insemination.
Cervical
Sperms Vagina Uterus Isthmus
canal
Ampullary-
isthmic Junction
Ovum Infundibulum
Fimbriae Ampulla
(from ovary)
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FERTILIZATION AND IMPLANTATION
• Fertilization happens only if ovum &
sperms are transported simultaneously.
So all copulations do not lead to
fertilization & pregnancy.
• A sperm comes in contact with zona
pellucida. It induces changes in the
membrane that block the entry of
additional sperms.
• The secretions of the acrosome help
sperm to enter into the egg cytoplasm
via zona pellucida and plasma
membrane. This causes second meiotic
division of the secondary oocyte to form
an ovum (ootid) and second polar body.
• The haploid nuclei of the sperm and
ovum fuse together to form a diploid
zygote. bankofbiology.com
FERTILIZATION AND IMPLANTATION
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FERTILIZATION AND IMPLANTATION
• The blastomeres in the
blastocyst are arranged into an
outer layer (trophoblast) and an
inner group of cells (inner cell
mass) attached to trophoblast.
• The trophoblast layer then gets
attached to endometrium.
• The inner cell mass gets
differentiated to 3 germ layers
(outer ectoderm, middle
mesoderm & inner endoderm).
This 3-layered structure
(gastrula) forms the embryo.
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FERTILIZATION AND IMPLANTATION
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?
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Fertilization occurs in
?
A. Fundus of uterus
B. Medulla of ovary
C. Ampullary-isthmic junction of oviduct
D. Infundibulum of oviduct
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Sperm enters into the ovum by the help of secretions from
?
A. Mitochondria
B. Acrosome
C. Ribosome
D. Centriole
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The embryo with 8-16 blastomeres is called
?
A. Blastula
B. Gastrula
C. Trophoblast
D. Morula
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PREGNANCY AND EMBRYONIC
DEVELOPMENT
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PREGNANCY AND EMBRYONIC DEVELOPMENT
After
implantation,
finger-like
projections
(chorionic villi)
appear on the
trophoblast which
is surrounded by
the uterine tissue
and maternal
blood.
• The chorionic villi & uterine tissue become interdigitated with each other to
form placenta.
• Placenta is a structural and functional unit b/w embryo (foetus) and maternal
body.
• Placenta is connected to the embryo by an umbilical cord. It transports
substances to and from the embryo. bankofbiology.com
PREGNANCY AND EMBRYONIC DEVELOPMENT
Functions of placenta
1. Acts as barrier between the foetus &
mother.
2. Supply O2, nutrients etc. from mother to
foetus.
3. Remove CO2 & excretory wastes from
foetus.
4. Acts as an endocrine gland. It secretes
Human chorionic gonadotropin (hCG),
human placental lactogen (hPL),
oestrogens, progesterone & relaxin.
Relaxin is also
secreted by ovary.
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PREGNANCY AND EMBRYONIC DEVELOPMENT
• During pregnancy,
levels of estrogens,
progestogens,
• Human
The germ pregnancy
layers give
cortisol, prolactin,
rise to all tissues
(gestation period)
thyroxine etc are also
(organs).
lasts 9 months.
The stem
increased in maternal
• For
cellscats:
in inner
2 months,
cell mass
blood.
have the
dogs: 2 months,
potency to
• They support the fetal
give rise to21
elephants: all the
growth, metabolic
tissues and organs.
months).
changes in the mother
and maintain
pregnancy.
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PREGNANCY AND EMBRYONIC DEVELOPMENT
Changes in embryo during pregnancy
• After one month: Heart is formed.
• End of second month: Limbs and
digits are developed.
• End of 12 weeks (first trimester):
The major organs (limbs, external
genital organs etc) are well
developed.
• During 5th month: First movement
of foetus and appearance of hair
on the head.
• End of 24 weeks (second
trimester): Body is covered with
fine hair, eyelids separate and
eyelashes are formed.
• End of 9 months: Ready for
delivery. bankofbiology.com
PARTURITION AND
LACTATION
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PARTURITION AND LACTATION
Parturition (labour)
• Process of giving birth to young ones.
• It is induced by neuroendocrine mechanism.
• The signals from the foetus and placenta
induce mild uterine contractions (fetal
ejection reflex). This causes the release of
oxytocin from maternal pituitary.
• Oxytocin causes stronger uterine muscle
contractions which in turn stimulate further
secretion of oxytocin. This process is
continued leading to expulsion of the baby
out of the uterus through the birth canal.
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PARTURITION AND LACTATION
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?
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Placenta
?
A. Is physiological connection between
mother and foetus.
B. Acts as endocrine gland.
C. Eliminates nitrogenous wastes of foetus.
D. All the above.
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Heart of the foetus is formed
?
A. After one week of pregnancy
B. After one month of pregnancy
C. By the end of first trimester
D. By the end of second trimester
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Process of giving birth to young ones is known as
?
A. Micturition
B. Parturition
C. Implantation
D. Gastrulation
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Name the hormone that causes stronger uterine muscle
contraction during labour
?
A. Relaxin from placenta
B. Oxytocin from foetal pituitary
C. Oxytocin from maternal pituitary
D. HCG from placenta
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The yellowish milk produced during the initial few days of
lactation is called
?
A. Colostrum
B. Callosum
C. Lactogen
D. Prolactin
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THE END
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Prepared by: K.C. MUHAMMED ALI
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