Aviv Regev
Aviv Regev (born 11 July 1971)[3] is a computational
biologist and systems biologist and Executive Vice Aviv Regev
President and Head of Genentech Research and Early
Development in Genentech/Roche.[4] She is a core
member (on leave) at the Broad Institute of MIT and
Harvard and professor (on leave) at the Department of
Biology of the Massachusetts Institute of
Technology.[5] Regev is a pioneer of single cell
genomics and of computational and systems biology of
gene regulatory circuits. She founded and leads the
Human Cell Atlas project,[6] together with Sarah
Teichmann.
Regev at the Intelligent Systems for Molecular
Biology conference in 2017
Education Born July 11, 1971[3]
Alma mater Tel Aviv University ([Link]., Ph.D.)
Regev studied at the Adi Lautman Interdisciplinary
Program for Outstanding Students of Tel Aviv Awards Overton Prize (2008)[1]
University, where she completed her PhD under the ISCB Innovator Award (2017)[2]
supervision of Eva Jablonka,[7] and Ehud Shapiro.[8] Paul Marks Prize for Cancer
Research (2017)
Member of the National
Career and research Academy of Sciences (2019)
Keio Medical Science Prize
In 2020, Regev became the Head and Executive Vice
(2020)
President of Genentech Research and Early
Development, based in South San Francisco, and a Scientific career
member of the extended Corporate Executive Fields Bioinformatics
Committee of Roche.[9][10] Previously, she was a Core Computational Biology
Institute Member (now on leave), Chair of the Faculty, Institutions Massachusetts Institute of
Founding Director of the Klarman Cell Observatory
Technology
and co-Director Cell Circuits Program at the Broad
Howard Hughes Medical
Institute of MIT and Harvard. She was also a professor
Institute
in the Department of Biology at the Massachusetts
Institute of Technology (now on leave), as well as an Broad Institute
Investigator at the Howard Hughes Medical Institute. Genentech
Regev's research[11] includes work on gene Doctoral Eva Jablonka
expression[12][13] (with Eran Segal and David advisor Ehud Shapiro
Botstein), and the use of π-calculus to represent
Website [Link]/scientists/our-
biochemical processes.[14][15][16] Regev's team has scientists/aviv-regev ([Link]
been a leading pioneer of single-cell genomics
experimental and computational methods.[17] In 2014, [Link]/scientists/our-scienti
she pitched the idea of the creation of Human Cell sts/aviv-regev)
Atlas, [18] a project to describe all cell types in the
human body. Regev founded the Human Cell Atlas together with Sarah Teichmann along with
collaborators all over the world.
Single Cell Genomics
Regev's lab pioneered the development and application of many of the key experimental and
computational advances for single cell and spatial genomics, especially single cell RNA-Seq (scRNA-
seq).
Awards and honors
Regev is a fellow of the International Society of Computational Biology (ISCB) (2017),[19] a Helmholtz
Fellow (2020),[20] and a fellow of the American Association for Cancer Research (AACR) (2021).[21] She
is a member of the US National Academy of Sciences (NAS, elected 2019)[22] and of the US National
Academy of Medicine (NAM, elected 2020).[23] She was elected as a foreign member of the Royal
Society [24] and as an associate member of the European Molecular Biology Organization in 2024.[25]
TED AI 2023 Talk: Can AI Help Develop New Medicines[26]
25th L'Oréal-UNESCO For Women in Science Awards (Laureate for North America),
2023[27]
Elected to the American Academy of Arts and Sciences, 2022[28]
Anderson Lecture, University of Virginia, 2022[29]
Nakasone Award from the Human Frontiers Science Program (2022)[30]
Honorary doctorate, ETH Zurich (2021)[31]
Ernst Schering Prize (2021)[32]
James Prize in Science and Technology Integration, National Academy of Sciences
(2021)[33]
Vanderbilt Prize (2021)[34]
She was awarded the 25th Keio Medical Science Prize in 2020.[35][36]
AACR-Irving Weinstein Foundation Distinguished Lecture (2021)[37]
Lurie Prize from the Foundation for the NIH (FNIH) (2020)[38]
Mendel Lecture, European Society of Human Genetics (2020)[39]
Jonathan Kraft Prize from Massachusetts General Hospital (2020)[40]
FASEB Excellence in Science Mid-Career Investigator Award (2019)[41]
She was elected a member of the National Academy of Sciences (NAS) in 2019.[42]
She also served on the Life Sciences jury for the Infosys Prize in 2018.
Weatherall Lecture, University Oxford, UK (2018)[43]
Harvey Lecture, Harvey Society, New York (2018)[44]
McCormick Lecture, Stanford University (2018)[45]
Paul Marks Prize for Cancer Research (2017).[46]
ISCB Innovator Award in 2017.[2][47]
Earl and Thressa Stadtman Scholar Award from the American Society of Biochemistry and
Molecular Biology (ASBMB) (2014)[48]
Burroughs Wellcome Fund Career Award.[49]
In 2008, she was also awarded the NIH Director's Pioneer Award.[50][51]
Regev was awarded the Overton Prize in 2008 for "outstanding accomplishment to a
scientist in the early to mid stage of his or her career".[1]
References
1. Sansom, C.; Morrison Mckay, B. J. (2008). Bourne, Philip E. (ed.). "ISCB Honors David
Haussler and Aviv Regev" ([Link] PLOS
Computational Biology. 4 (7): e1000101. Bibcode:2008PLSCB...4E0101S ([Link]
[Link]/abs/2008PLSCB...4E0101S). doi:10.1371/[Link].1000101 ([Link]
10.1371%[Link].1000101). PMC 2536508 ([Link]
s/PMC2536508). PMID 18795145 ([Link]
2. Fogg, Christiana N.; Kovats, Diane E.; Berger, Bonnie (2017). "2017 ISCB Innovator Award:
Aviv Regev" ([Link] PLOS
Computational Biology. 13 (6): e1005558. Bibcode:2017PLSCB..13E5558F ([Link]
[Link]/abs/2017PLSCB..13E5558F). doi:10.1371/[Link].1005558 ([Link]
g/10.1371%[Link].1005558). ISSN 1553-7358 ([Link]
3-7358). PMC 5493285 ([Link]
PMID 28665936 ([Link]
3. "Aviv Regev" ([Link]
rg/mgarber/[Link]) (PDF). [Link]. Archived from the original ([Link]
[Link]/mgarber/[Link]) (PDF) on 16 November 2017. Retrieved
2 December 2021.
4. GENENTECH EXECUTIVE COMMITTEE ([Link]
utive-committee), accessed 6 August 2020.
5. "Aviv Regev at MIT" ([Link]
eople/aviv_regev). [Link]. Archived from the original ([Link]
aviv_regev) on 6 April 2017. Retrieved 5 November 2017.
6. Nowogrodzki, Anna (5 July 2017). "How to build a human cell atlas" ([Link]
8%2F547024a). Nature. 547 (7661): 24–26. Bibcode:2017Natur.547...24N ([Link]
[Link]/abs/2017Natur.547...24N). doi:10.1038/547024a ([Link]
547024a). PMID 28682347 ([Link] S2CID 211067156
([Link]
7. Regev, A.; Lamb, M. J.; Jablonka, E. (1998). "The Role of DNA Methylation in Invertebrates:
Developmental Regulation or Genome Defense?" ([Link]
[Link].a025992). Molecular Biology and Evolution. 15 (7): 880.
doi:10.1093/[Link].a025992 ([Link]
ev.a025992). ISSN 0737-4038 ([Link]
8. Regev, A.; Shapiro, E. (2002). "Cellular abstractions: Cells as computation" ([Link]
[Link]/pmc/articles/PMC3842595). Nature. 419 (6905): 343.
Bibcode:2002Natur.419..343R ([Link]
doi:10.1038/419343a ([Link] PMC 3842595 ([Link]
[Link]/pmc/articles/PMC3842595). PMID 12353013 ([Link]
12353013).
9. Taylor, Nick Paul (11 May 2020). "Genentech lures Regev from Broad Institute to lead
research and early development" ([Link]
gev-from-broad-institute-to-lead-research-and-early-development). [Link].
Retrieved 25 May 2020.
10. "Changes to the Roche Enlarged Corporate Executive Committee" ([Link]
[Link]/news-release/2020/05/11/2030716/0/en/Changes-to-the-Roche-Enlarged-Corpora
[Link]) (Press release). Basel, Switzerland: F. Hoffmann-La Roche
Ltd. globenewswire. 11 May 2020. Retrieved 25 May 2020.
11. Search Results for author Regev A ([Link]
v%20A%22%5BAuthor%5D) on PubMed.
12. Segal, E.; Shapira, M.; Regev, A.; Pe'er, D.; Botstein, D.; Koller, D.; Friedman, N. (2003).
"Module networks: Identifying regulatory modules and their condition-specific regulators
from gene expression data". Nature Genetics. 34 (2): 166–176. doi:10.1038/ng1165 (https://
[Link]/10.1038%2Fng1165). PMID 12740579 ([Link]
S2CID 6146032 ([Link]
13. Segal, E.; Friedman, N.; Koller, D.; Regev, A. (2004). "A module map showing conditional
activity of expression modules in cancer" ([Link]
71138). Nature Genetics. 36 (10): 1090–1098. doi:10.1038/ng1434 ([Link]
8%2Fng1434). PMC 2271138 ([Link]
PMID 15448693 ([Link]
14. Regev, A.; Silverman, W.; Shapiro, E. (2001). "Representation and simulation of biochemical
processes using the pi-calculus process algebra". Pacific Symposium on Biocomputing:
459–470. doi:10.1142/9789814447362_0045 ([Link]
0045). ISBN 978-981-02-4515-3. PMID 11262964 ([Link]
64).
15. Priami, C.; et al. (2001). "Application of a stochastic name-passing calculus to
representation and simulation of molecular processes" ([Link]
df) (PDF). Information Processing Letters. 80: 25–31. doi:10.1016/S0020-0190(01)00214-9
([Link]
16. Study provides insight into regenerative potential of prostate gland ([Link]
[Link]/news/20200430/Study-provides-insight-into-regenerative-potential-of-prostate-gland.a
spx), News Medical, accessed 4 May 2020.
17. "Aviv Regev" ([Link] [Link]. Retrieved 11 May
2020.
18. The Human Cell Atlas – Aviv Regev ([Link]
August 2014, retrieved 30 May 2022
19. "2017 ISCB Innovator Award: Aviv Regev" ([Link]
2520About%2520Us/awards6/3070-2017-innovator-award-aviv-regev). [Link].
Retrieved 14 March 2022.
20. "Event – Helmholtz Zentrum München" ([Link]
s/event/article/49006/[Link]). [Link]. Retrieved 14 March 2022.
21. "Aviv Regev, PhD, FAACR | Scientific Awards | AACR" ([Link]
v-regev-phd-faacr/). American Association for Cancer Research (AACR). Retrieved
14 March 2022.
22. "Aviv Regev" ([Link]
[Link]. Retrieved 14 March 2022.
23. "National Academy of Medicine Elects 100 New Members" ([Link]
my-of-medicine-elects-100-new-members-2020/). National Academy of Medicine. 19
October 2020. Retrieved 14 March 2022.
24. "Outstanding scientists elected as Fellows of the Royal Society" ([Link]
s/2024/05/new-fellows-2024/).
25. "EMBO elects 2024 members" ([Link]
elects-2024-members).
26. "Aviv Regev: Can AI Help Develop New Medicines" ([Link]
an_ai_help_develop_new_medicines?subtitle=en). 9 August 2024.
27. "Discover the laureates of the 25th L'Oréal-UNESCO For Women in Science International
Awards | UNESCO" ([Link]
co-women-science-international-awards). [Link]. Retrieved 2 June 2023.
28. "New Members" ([Link] American Academy of Arts
& Sciences. Retrieved 30 May 2022.
29. "The Events Calendar" ([Link]
=9735AAC5-17A4-7750-30B180BC96DDC33E&eventdate=04/18/2022).
30. "Press Release – 2022 HFSP Nakasone Award" ([Link]
ss-release-2022-hfsp-nakasone-award).
31. Foppa, Carolin Arndt (22 November 2021). "Pioneer in bioinformatics receives ETH
Honorary doctorate" ([Link]
-[Link]). [Link]. Retrieved 18 March
2022.
32. "Ernst Schering Prize 2021 – Schering Stiftung" ([Link]
benswissenschaften/ernst-schering-preis/ernst-schering-preis-2021/). Retrieved 18 March
2022.
33. "James Prize in Science and Technology Integration" ([Link]
wards/[Link]). [Link]. Retrieved 18 March 2022.
34. Snyder, Bill (28 April 2021). "Regev receives Vanderbilt Prize in Biomedical Science" (http
s://[Link]/2021/04/28/regev-receives-vanderbilt-prize-in-biomedical-science/).
Vanderbilt University. Retrieved 18 March 2022.
35. "Award Ceremony for the 25th Keio Medical Science Prize" ([Link]
2020/Dec/7/48-76824/?fbclid=IwAR0BXC_52zYLLeWqS5Ph-ByFEFgfPY1CKgqmQO92SvI
bUpY0-IiIYZYX9jA). [Link]. Retrieved 22 December 2020.
36. "Announcement of the 25th Keio Medical Science Prize – News – Keio University Medical
Science Fund" ([Link]
The%2025th%20Keio%20Medical%20Science%20Prize%20is%20awarded%20to%20Dr,Ja
pan%27s%20largest%20comprehensive%20research%20institution.). [Link]-
[Link]. Retrieved 18 March 2022.
37. "Aviv Regev, PhD, FAACR | Scientific Awards | AACR" ([Link]
v-regev-phd-faacr/). American Association for Cancer Research (AACR). Retrieved
18 March 2022.
38. "2020 FNIH Lurie Prize in Biomedical Sciences Winner Pioneered Innovative Techniques to
Shed New Light on Human Health | The Foundation for the National Institutes of Health" (htt
ps://[Link]/news/press-releases/2020-fnih-lurie-prize-biomedical-sciences-winner-pioneere
d-innovative). [Link]. 18 June 2020. Retrieved 18 March 2022.
39. Wimmer, Doris. "Aviv Regev" ([Link]
mendel-lecture/). ESHG Conference 2020. Retrieved 14 March 2022.
40. "Kraft Prize Symposium" ([Link]
arch/center-for-cancer-research/news-and-events/kraft-prize-symposium). Massachusetts
General Hospital. Retrieved 14 March 2022.
41. "Past Recipients" ([Link]
[Link]. Retrieved 14 March 2022.
42. "2019 NAS Election" ([Link]
[Link]). [Link]. Retrieved 30 April 2019.
43. "Weatherall Lectures — MRC Weatherall Institute of Molecular Medicine" ([Link]
[Link]/about/seminars/weatherall-lectures). [Link]. Retrieved 14 March 2022.
44. "The Harvey Society: Series 113, Lecture 5" ([Link]
p?series=113&lecture=5). [Link]. Retrieved 14 March 2022.
45. "MIT's Aviv Regev to present annual McCormick Lecture Feb. 1" ([Link]
ws/all-news/2018/01/[Link]).
News Center (in Samoan). Retrieved 14 March 2022.
46. "2017 Prize Winners" ([Link]
esearch/2017-prize-winners). Memorial Sloan Kettering Cancer Center. Retrieved
12 December 2017.
47. "February 09, 2017: ISCB Announces 2017 Award Recipients" ([Link]
ws-items/3066-2017-feb09-iscb-awards-2017). [Link]. Retrieved 10 February 2017.
48. "Regev recognized for rigorous integration of experimental and computational approaches"
([Link]
nal-award). [Link]. Retrieved 14 March 2022.
49. Dynamic single-cell imaging of direct reprogramming reveals an early specifying event –
Nature Biotechnology: Aviv Regev, Ph.D. – Career Awards at the Scientific Interface; Ab
initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved
multi-exonic structure of lincRNAs – Nature Biotechnology: Aviv Regev, Ph.D. – Career
Awards at the Scientific Interface ([Link]
50. "Three faculty win '08 NIH Pioneer Awards" ([Link]
nih-pioneer-awards). MIT News | Massachusetts Institute of Technology. 22 September
2008. Retrieved 6 March 2022.
51. "2008 NIH Director's Pioneer Award" ([Link]
[Link]/awards-and-accolades-summer-2008). Archived from the original ([Link]
[Link]/awards-and-accolades-summer-2008) on 30 July 2019. Retrieved 30 July
2019.
Retrieved from "[Link]