Seat No.: _____ Enrolment No.

_____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER– 6 EXAMINATION – SUMMER-2024

Subject Code:BP602TP Date: 02/05/2024

Subject Name: Pharmacology III
Time: 10.30 a.m. to 1.30 p.m. Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Classify antifungal agents. Write a note on azole group of antifungals. 06
(b) Write in detail about pharmacology of Aminoglycosides. 05
(c) Describe Expectorants in detail. 05

Q.2 (a) Classify antiemetics. Explain mechanisms of Prokinetic drugs. 06

(b) Describe clinical symptoms and management of Organophosphorus poisoing. 05
(c) Classify Purgatives. Write a note on Bulk purgatives. 05

Q.3 (a) Classify Anti-asthmatics and discuss about bronchodilators. 06

(b) Write a note on Proton Pump Inhibitors. 05
(c) Describe Immunosuppressants. 05

Q.4 (a) Explain mechanism of action of (i) Penicillin (ii) Fluoroquinolones 06

(b) Explain various Biochemical mechanisms of resistance to antibiotics. 05
(c) Classify antituberculosis agents and write a note on DOTS therapy. 05

Q.5 (a) Explain life cycle of HIV virus and write a note on Zidovudine. 06
(b) Describe role of biological clock in chronotherapy. 05
(c) Explain adverse effects of (i) Chloramphenicol (ii) Sulfonamides 05

Q.6 (a) Write down pathophysiology & management of COPD. 06

(b) Describe Anthelmintics. 05
(c) Write in detail about drugs used in Syphilis & Gonorrhea. 05

Q.7 (a) Explain the following terms 06

(i) Carcinogenicity (ii) Teratogenicity (iii) Genotoxicity
(b) Discuss the role of antimetabolites in Cancer. 05
(c) Explain mechanism, therapeutical uses and side effects of Tetracyclines. 05
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER– 6 EXAMINATION – SUMMER -2023

Subject Code: BP602TP Date: 20/06/2023

Subject Name: Pharmacology III
Time:10.30 a.m. to 1.30 p.m. Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Write down Mechanism of Action of Following drugs. 06

A) Clavunic Acid
B) Ziduvudine
C) Methotrexate
(b) Classify Anti-asthmatics Drugs 05
(c) Write down Pharmacology of Metronidazole. 05

Q.2 (a) Write note on bacterial Cell Wall Synthesis inhibitors. 06

(b) Write note on Drugs which is used in Urinary Tract Infections. 05
(c) Comment on Following Statement: 05
a) Probenecid is given with Penicillin
b) Pyridoxine is given with Isoniazid

Q.3 (a) Define Immunopharmacology. Classify Immunosuppressant Drugs. Write 06

Mechanism of action of Cyclosporine
(b) Write Classification of Anticancer Drugs. 05
(c) Write note on Non-Nucleoside Reverse Transcriptase Inhibitor. 05

Q.4 (a) Classify Antiviral Drugs according its Mecahnism of Action. 06

(b) Write down Mechanism of Action & therapeutic uses of Chloramphenicol. 05
(c) Write down Mechanism of action & Therapeutic Use of Co-trimoxazole 05

Q.5 (a) Enlist Various Anti-Malarial Drugs. Discuss Pharmacology Primaquine 06

(b) Describe Adverse Effect of Aminoglycoside Antibiotics 05
(c) Classify Antiemetics.Decribe any one in Detail. 05

Q. 6 (a) Explain Following Term: 06

a) Fancony Like Syndrome
b) Gray Baby Syndrome
c) Ototoxicity
(b) Discuss the Pharmacology of Antiulcer Agents. 05
(c) Enlist First line Drugs used in Tuberculosis 05

Q.7 (a) Write Mechanism of Action of Following Drugs 06

a) Clarithromycin
b)Acyclovir
c)Metronidazole
(b) Write Pharmacology of Azithromycin 05
(c) Write note on General Principle of Treatment of Poisoning 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph. - SEMESTER–VI • EXAMINATION –SUMMER -2022

Subject Code:BP602TP Date: 03/06/2022

Subject Name: Pharmacology-III
Time: 10:30AM TO 01:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define Resistance. Write note on Mechanism of Resistance. 06

(b) Write Classification of Anticancer Drugs. 05
(c) Write down Pharmacology of Sulphonamide 05

Q.2 (a) Write note on bacterial Cell Wall Synthesis inhibitors. 06

(b) Classify Anti-asthmatics Drugs 05
(c) Write note on Drugs which is used in Urinary Tract Infections. 05

Q.3 (a) Define Immunopharmacology. Classify Immunosuppressant Drugs. Write 06

Mechanism of action of Cyclosporine
(b) Classify Antiemetics.Decribe any one in detail. 05
(c) Write note on Non-Nucleoside Reverse Transcriptase Inhibitor. 05

Q.4 (a) Classify Antiviral Drugs according its Mecahnism of Action. 06

(b) Write note on General Principle of Treatment of Poisoning 05
(c) Explain Following Term: Teratogenicity & Carcinogenicity 05

Q.5 (a) Enlist Various Anti-Malarial Drugs. Discuss Pharmacology Primaquine 06

(b) Describe Adverse Effect of Aminoglycoside Antibiotics 05
(c) Comment on Following Statement: 05
a) Probenecid is given with Penicillin
b) All Chemotherapeutics Agents are Antibiotics.
Q. 6 (a) Explain Following Term: 06
a)Fancony Like Syndrome
b)Gray Baby Syndrome
c)Kernicterus
(b) Classify Cephalosporins. 05
(c) Enlist First line Drugs used in Tuberculosis 05
Q.7 (a) Write Mechanism of Action of Following Drugs 06
a)Clavunic Acid
b)Acyclovir
c)Metronidazole
(b) Write Pharmacology of Azithromycin 05
(c) Discuss the Pharmacology of Antiulcer Agents. 05

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Seat No.: _____ Enrolment No._____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Pharm.– SEMESTER–VI - EXAMINATION – SUMMER-2021

Subject Code: BP602TP Date: 04/08/2021

Subject Name: Pharmacology-III
Time: 02:30 PM To 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Explain the role of biological clocks in cancer processes and chronotherapy in 06
detail.
(b) Define Immunomodulator. Discuss in detail about cyclosporine. 05
(c) Write a note on antifungals. 05
Q.2 (a) What is DOTS? Explain the clinical signs, symptoms and diagnostic tests of 06
Tuberculosis.
(b) Explain in detail the pharmacology of Ciprofloxacin. 05
(c) Write a note on macrolides. 05
Q.3 (a) Describe the terms (with examples): Biosimilars, Monoclonal antibodies and 06
Chronopharmacology.
(b) Outline the complete life cycle of Malarial parasite. Discuss the use of 05
“Co-artemether”.
(c) Classify antiemetic drugs. Discuss mechanism of prokinetic drugs. 05
Q.4 (a) Write about etiology, pathophysiology and treatment of COPD. 06
(b) Write in detail about the drugs used in treatment of Syphilis and Gonorrhea. 05
(c) Write a note on anthelmentics. 05
Q.5 (a) Explain the clinical symptoms and management of barbiturates and morphine 06
poisoning.
(b) What is HAART? Write a note on drugs used in treatment of HIV infection. 05
(c) Classify laxatives and purgatives. Add a note on irritant laxatives with example. 05
Q. 6 (a) Classify anticancer drugs highlighting their mechanism of action. 06
(b) Describe pathophysiology and treatment of bronchial asthma. 05
(c) Write a note on antitussive agents. 05
Q.7 (a) Classify types of Leprosy. Write detail pharmacology of Dapsone. 06
(b) Discuss the management of UTI. 05
(c) Write a brief note on Digestants and carminatives. 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER– 6 EXAMINATION – SUMMER -2020

Subject Code:BP602TP Date: 27-10-2020

Subject Name: PHARMACOLOGY III
Time: 10:30 AM TO 1:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Write mechanism of action, side effects of 1) Nelfinavir 2) Isoniazid 06

3) Tamoxifen.
(b) What is HAART? Write a note on drugs used in treatment of HIV infection. 05
(c) Classify antifungal agents & write a note on azoles as antifungal agent. 05
Q.2 (a) Classify third generation Cephalosporin’s & write its MOA and therapeutic 06
actions.
(b) What is drug resistance? Write different mechanisms of transfer of resistance 05
genes within and among bacteria.
(c) Explain the following terms : i)Acute toxicity ii) Superinfection iii) Jarish 05
Herxheimer reaction iv) Cross resistance v) Kernicterus
Q.3 (a) Classify types of Leprosy. Write detail pharmacology of Dapsone. 06
(b) Explain in brief tissue schizontocidal agents. 05
(c) Explain in detail MDR-TB and write a note on DOTS. 05
Q.4 (a) Classify Laxatives. Explain Osmotic purgatives. 06
(b) Write MOA of following drugs: i) Metoclopramide ii) Mesalazine iii) 05
Etofamide iv) Foscarnet v) Doxorubicin
(c) Write a note on anthelmintics. 05
Q.5 (a) Write a note immunostimulants. 06
(b) Discuss the role of antimetabolites in treatment of cancer. 05
(c) Discuss treatment and management of diarrhea with emphasis on ORT. 05
Q. 6 (a) Write in detail the drugs used in treatment of Syphilis and Gonorrhea. 06
(b) Classify the drugs used in treatment of UTI. Write a note on Quinolones. 05
(c) Explain in brief the mechanism of biological agents as immunosuppressants. 05
Q.7 (a) Explain the use of Leukotriene antagonists in treatment of asthma. 06
(b) Define cough. Differentiate between Expectorants and Antitussive agents 05
(c) Explain the role of chronology in occurrence of various diseases. 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER– 6 EXAMINATION – WINTER -2024

Subject Code:BP602TP Date: 21-11-2024

Subject Name: Pharmacology III
Time:02.30 PM TO 05.30 PM ` Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Classify Anti-asthmatics drugs. Discuss the mechanism of action, adverse 06
effects and uses of methyl xanthines.
(b) Write a short note on antitussives. 05
(c) Write mechanism of action and therapeutic uses of fluoroquinolones. 05
Q.2 (a) Discuss the mechanism of action, adverse effects and uses of aminoglycosides. 06
(b) Write a short note on DOTS. 05
(c) Write a short note on immunosuppressants. 05
Q.3 (a) Enlist Various anti-malarial drugs. Discuss pharmacology of Primaquine. 06
(b) Differentiate the terms: Acute, Subacute and Chronic toxicity. 05
(c) Write a short note on anthelmintics. 05
Q.4 (a) Discuss the pharmacology of Proton Pump Inhibitors. 06
(b) Define Expectorants? Write a short note on Expectorants. 05
(c) Write note on general principles of chemotherapy. 05
Q.5 (a) Discuss the symptoms and management of barbiturates and morphine 06
poisoning.
(b) Write classification of anticancer drugs. 05
(c) Explain the terms: Teratogenicity & Carcinogenicity 05
Q. 6 (a) Classify sulphonamides and explain its mechanism of action and adverse 06
effects.
(b) Write a short note on antifungal agents. 05
(c) Write note on general principles of treatment of poisoning. 05
Q.7 (a) Write a note on drugs used in Urinary Tract Infections. 06
(b) Explain the role of chronology in occurrence of various diseases. 05
(c) Write a note on Nucleoside Reverse Transcriptase inhibitor (NRTI). 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER–6 EXAMINATION – WINTER -2023

Subject Code: BP602TP Date: 05/12/2023

Subject Name: Pharmacology III
Time: 02.30 p.m. to 5.30 p.m. Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Write mechanism of actions of following drugs: (i) Azithromycin (ii) 06
Ciprofloxacin (iii) Doxycycline
(b) Write a note on drugs used in the management of COPD 05
(c) Classify Antifungal agents. Describe mechanism of action and adverse effects 05
of Amphotericin B.
Q.2 (a) Describe the following terms with examples: (i) Biosimilars (ii) Monoclonal 06
antibodies (iii) Chronopharmacology.
(b) Discuss the management of UTI. 05
(c) Define Immunomodulator. Discuss in detail about cyclosporine. 05
Q.3 (a) Write mechanism of action and advese effects of following drugs: 06
(i) Oseltamivir (ii) Isoniazid (iii) Tamoxifen.
(b) Classify Antimalarial drugs.Write pharmacology of Chloroquine 05
(c) Write in detail about the drugs used in treatment of Syphilis and Gonorrhea. 05
Q.4 (a) Classify anti asthmatic drugs. Describe role of sympathomimetics in the 06
treatment of asthma.
(b) Discuss the role of antimetabolites in treatment of cancer. 05
(c) What is drug resistance? Write different mechanisms of transfer of resistance 05
genes within and among bacteria.
Q.5 (a) Classify Cephalosporin. Write MOA and therapeutic actions of third generation 06
Cephalosporin’s.
(b) Classify Laxatives. Explain Osmotic purgatives. 05
(c) Define cough. Differentiate between Expectorants and Antitussive agents 05
Q. 6 (a) Describe Pharmacology of Proton Pump Inhibitor 06
(b) Classify Antiemetics. Write pharmacology of ondansetron. 05
(c) Discuss signs, symptoms & management of morphine and organophosphorus 05
poisoning
Q.7 (a) Define following term: (1) Teratogenicity (2) Genotoxicity (3) Sub acute 06
toxicity (4) Biological clock (5) Anthelmintics (6) Carminatives
(b) Classify sulphonamides and explain its mechanism of action and adverse 05
effects.
(c) Comment on following statement: 05
(i) Cotrimoxazole is preferred over sulfonamide alone.
(ii) Probenecid is administerd with Penicillin.

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Seat No.: ___________ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Pharm. – SEMESTER 6 • EXAMINATION – WINTER -2022

Subject Code: BP602TP Date:27/12/2022

Subject Name: Pharmacology III
Time: 02:30pm to 05:30pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Classify Anti-asthmatic drugs.Discuss pharmacology of Sodium cromoglycate 06

(b) Write a detailed note on Immunosuppressant. 05
(c) Give mechanism of action of following drugs 05
1. Isoniazid 2. Amphotericin B
Q.2 (a) Explain Drug resistance in detail. Discuss approaches to prevent drug resistance 06
(b) Describe pharmacology of Dapsone. 05
(c) Classify Antiemetics. Write pharmacology of ondansetron. 05
Q.3 (a) Classify Antimalarial drugs.Write pharmacology of Chloroquine 06
(b) Write a note on Expectorant 05
(c) Give Reason: Cotrimoxazole is preferred over sulfonamide alone. 05
Q.4 (a) Describe Pharmacology of Proton Pump Inhibitor 06
(b) Discuss Common properties of Aminoglycosides 05
(c) Discuss mechanism of action and adverse effects of Alkylating agents. 05
Q.5 (a) Discuss mechanism of action, adverse effects and therapeutic uses of 06
Fluoroquinolones
(b) Classify Purgative. Write a note on Bulk Purgative 05
(c) Discuss acute toxicity. 05
Q. 6 (a) Classify Cephalosporin. Discuss mechanism of action & therapeutic uses of 06
Cefixime
(b) Explain following terms 05
1. Teratogenicity 2. Mutagenicity
(c) Discuss signs and symptoms & management of Organophosphorus poisoning 05
Q.7 (a) Classify Antiretroviral Drugs. Write a note on Nucleoside Reverse 06
Transcriptase inhibitor (NRTI).
(b) Explain biological clock with its significance. 05
(c) Discuss adverse effects of following drugs 05
1. Ketoconazole 2.Rifampicin

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph. – SEMESTER VI • EXAMINATION – WINTER -2021

Subject Code: BP602TP Date: 25/11/2021

Subject Name: PHARMACOLOGY III
Time: 02:30pm to 05:30pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Discuss Mechanism of action, Therapeutic uses and Adverse effects of Proton 06
Pump Inhibitors
(b) Discuss the role of Oral Rehydration Therapy (ORT) in the treatment of 05
Diarrhoea
(c) What is Cotrimoxazole? Why Cotrimoxazole is preferred over Sulfonamide 05
alone in bacterial infections?
Q.2 (a) What is Expectorant? Write a note on Expectorant 06
(b) Discuss Common properties of Aminoglycoside antibiotic. 05
(c) Classify Antiviral agents, Write mechanism of action and Adverse effects of 05
Acyclovir
Q.3 (a) Classify Antiasthmatic Drugs. Discuss Pharmacology of Leukotriene 06
Antagonists
(b) Write a note on Pharmacology of Artimisinin derivatives used in the treatment 05
of Malaria.
(c) Discuss general principles of Chemotherapy of Cancer 05
Q.4 (a) Classify Antifungal agents. Describe mechanism of action and adverse effects of 06
Ketoconazole
(b) Write mechanism of action and Therapeutic Uses of following Drugs 05
(i) Sodium Cromoglycate (ii) Theophylline
(c) Classify the drugs used in the treatment of UTI and Discuss adverse effects of 05
Ciprofloxacin
Q.5 (a) Write mechanism of actions of following drugs 06
(i) Ofloxacin (ii) Azithromycin (iii) Doxycycline
(b) What is Drug Resistance? Suggest measures for prevention of Drug Resistance 05
(c) Write a note on Immunosuppressant 05
Q. 6 (a) Explain following terms 06
(i) Teratogenicity (ii) Carcinogenicity (iii) Gray baby Syndrome
(b) Describe Clinical symptoms and management of Organophosphorus poisoning 05
(c) Write mechanism of action, therapeutic uses and adverse effects of 05
Metronidazole
Q.7 (a) Explain role of biological clock in chronotherapy 06
(b) How barbiturate poisoning can be managed? 05
(c) Write a note on Antiemetic agents. 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Pharm. - SEMESTER–VI • EXAMINATION – WINTER -2020

Subject Code: BP602TP Date: 05/01/2021

Subject Name: PHARMACOLOGY III
Time: 02:00PM TO 04:00PM Total Marks: 54
Instructions:
1. Attempt any THREE questions from Q-1 to Q-6.
2. Q.7 is compulsory to attempt.
3. Make suitable assumptions wherever necessary.
4. Figures to the right indicate full marks.

Q.1 (a) Classify anti asthmatic drugs. Describe role of sympathomimetics in the 06
treatment of asthma.
(b) Explain drug therapy for diarrhea. 05
(c) Write a note on antitussives. 05
Q.2 (a) Classify semi synthetic penicillins. Write antibacterial spectrum and therapeutic 06
uses of amoxycillin.
(b) Write a note on proton pump inhibitors. 05
(c) Write in detail about systemic antifungal agents. 05
Q.3 (a) Classify anticancer agents. Discuss anti metabolites in detail. 06
(b) Describe the characteristics and mechanism of action of aminoglycosides. 05
(c) Describe mechanism of action and adverse effects of chloramphenicol. 05
Q.4 (a) Classify immunosupressants. Describe pharmacology of ciclosporin. 06
(b) Write a note on anthelmintics. 05
(c) Define following term: 1) Teratogenicity 2) Chronobiology 3) Sub acute toxicity 05
4) Antibiotics 5) Drug resistance
Q.5 (a) What is DOTS? Discuss the management of tuberculosis with special emphasis 06
on Isoniazid.
(b) Classify anti-malarial drugs. Write adverse effects of chloroquine. 05
(c) Write a note on sexually transmitted diseases. 05
Q. 6 (a) Classify antiviral drugs. Describe pharmacology of acyclovir. 06
(b) Discuss signs-symptoms and complications of various urinary tract infections. 05
(c) Write mechanism of action and therapeutic uses of fluoroquinolones. 05
Q.7 (a) Classify sulphonamides and explain its mechanism of action and adverse effects. 06
OR
(a) Classify antiemetic drugs. Explain prokinetic drugs. 06
OR
(a) Discuss symptoms and management of organophosphorus poisoning. 06

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