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Formulation and evaluation of hair fall control herbal hair oil

Article in International Journal of Pharmacognosy and Life Science · July 2023

DOI: 10.33545/27072827.2023.v4.i2a.93

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 International Journal of Pharmacognosy and Life Science 2023; 4(2): 69-76

E-ISSN: 2707-2835
P-ISSN: 2707-2827
www.pharmacognosyjournal.com Formulation and evaluation of hair fall control herbal
IJPLS 2023; 4(2): 69-76
Received: 13-09-2023 hair oil
Accepted: 19-10-2023

Pooja Khanpara Pooja Khanpara, Anish Sorathiya, Chirag Sarapdadiya, Tulsi Tilva and
Associate Professor,
Department of Dr. Shital Faldu
Pharmacognosy, ORCID No:
0000-0003-1203-2969, Smt. R. DOI: https://doi.org/10.33545/27072827.2023.v4.i2a.93
D. Gardi B. Pharmacy College,
Gujarat Technological
University, Rajkot, Gujarat, Abstract
India Clinical studies have demonstrated the benefits of herbs and herbal oil for hair growth. The primary
issues linked to hair loss include dandruff, hair fading, and hair falling out, which are issues that both
Anish Sorathiya men and women find quite concerning. There are some synthetic medications for hair loss which
B. Pharm Scholar, Smt. R. D. exhibit serious adverse effects in addition to not providing an effective cure. The primary goal of this
Gardi B. Pharmacy College, work is to create a herbal hair oil formulation that can address hair loss and other hair -related issues.
Gujarat Technological Herbs like Murraya koenigii, Lawsonia inermis, Azadirachta indica, Vitex negundo, Phyllanthus
University, Rajkot, Gujarat, emblica, Centella asiatica, Hibiscus rosa sinensis, Cederwood oil and Rosmerry oil were selected for
India the formulations of hair fall control herbal hair oil.
Chirag Sarapdadiya Keywords: Herbs, hair growth, oil, formulation, evaluation, hair fall control
B. Pharm Scholar, Smt. R. D.
Gardi B. Pharmacy College,
1. Introduction
Gujarat Technological
University, Rajkot, Gujarat, Hair loss is a distressing situation for an increasing number of men and women both. It is
India great importance in develop new remedies for the treatment of loss of hair and other
ailments, aggression of hair. They also promote hair growth [1, 2]. Hair is one of the important
Tulsi Tilva parts of the body and is seen as a protective addition of the body and an auxiliary structure of
Associate Professor, the skin, along with sebaceous glands, sweat glands and nails. The basic parts of the hair are
Smt. R. D. Gardi B. Pharmacy
College, Gujarat Technological the earth (swelling of the base starting from the dermis), roots (this is the hair below the
University, Rajkot, Gujarat, surface of the skin), shafts (this is the hair above the surface of the skin) [3, 4]. We used
India vegetable hair oil for the hair treatment. Herbal hair oil not only moisturizes the scalp, but
also restores dry scalp and dry hair. It provides many essential nutrients needed to maintain
Dr. Shital Faldu normal sebum function and promote natural hair growth [5, 6].
Principal, Smt. R. D. Gardi B.
Pharmacy College, Gujarat
Technological University, 2. Introduction about Herbs Used
Rajkot, Gujarat, India 2.1 Henna [7-10]
 Biological source: Leaves of Lawsonia inermis L.
 Family: Lythraceae
 Synonym: Sepia, Auburn, Russet
 Vernacular Name: Henna
 English Name: Mehendi, Mendhi
 Hindi Name: Mehndi
 Ayurvedic Name: Mendhika, Madayanti
 Sidhha/Tamil: Alvanam, Aivani
 Chemical Constituents: 2-Hydroxy-1,4-napthoquinone, 1,4dihydroxy-naphthalene,
1,4-naphthoquinone, luteolins, apigenin, and their glycosides, fraxetin, scopletin, β-
Corresponding Author: sitosterol, tannin, gallic acid, glucose, mannitol, fat, resin and mucilage.
Pooja Khanpara
Associate Professor,
Department of
Pharmacognosy, ORCID No:
0000-0003-1203-2969, Smt. R.
D. Gardi B. Pharmacy College,
Gujarat Technological
University, Rajkot, Gujarat,
India

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medicine. Has innumerable medicinal properties Due to

Vitex, the plant also has widely used in the treatment
of. Already used Lots of complaints.

Fig 1: Henna leaves

2.2.1 Uses Fig 2: Nirgundi leaves

 It is used for the Growth of hair and hair fall control
 For coloring grey hair 2.3 Amla [12-16]
 Treatment of epilepsy and Jaundice  Biological source: Dried fruits of Phyllanthus emblica
 It is used as a remedy for malignant ulcers.  Family: Phyllanthaceae
 In headache  Synonyms: Emblica, Indian goose berry, Amla.
 Antibacterial, Antifungal  Vernacular Name: Amla
 Habitat: North Africa, India, Sri Lanka, and the  English Name: Emblica myroblan
Middle East 10  Hindi Name: Amla
 Propagation: By seeds  Ayurvedic Name: Dhatriphala, Amla, Amalaki,
 Useful Part: Leave Amalakan, Sriphalam, Vayastha
 Description: It is a heavily branched, deciduous, bare,  Unani: Aaonwala, Amlaj
sometimes thorny shrub, or a small tree with a grayish-  Sidhha/Tamil: Nellikai
brown bark that reaches 2.45 m in height. It is  Chemical Constituents: Fruits contain about 28% of
cultivated throughout India as a hedge and is cultivated the tannins in the whole plant. This tannin has two
throughout India. Leaves- size:1.3-3.2 by 0.6-1.6 cm hydrolyzable forms. (I) Embricanin A and (ii)
Embricanin B are naturally antioxidants. Embricanin A
2.2 Nirgundi [11] provides ellagic acid, glucose and gallic acid when
 Biological source: It is obtained from leaves of Vitex hydrolyzed, whereas embricanin B is hydrolyzed to
negundo form ellagic acid and glucose. This fruit is also a source
 Family: Verbenaceae of fillembrin. Further fractionation revealed the
 Synonyms: Sinduvara, Sephali presence of many other phytochemicals. H. Geraniin,
 Vernacular Name: Five-Leaved Chaste Tree, corilagin, gallic acid, frosin.
 English Name: Chinese chaste tree, five-leaved, chaste
tree, Indian privet
 Hindi Name: Bheudi, Mewri, Nengar, Ningori,
Nigandi, Nirgandi
 Ayurvedic Name: Sinduka, Nisinda,
 Unani: Nisinda
 Sidhha/Tamil: Venmochi, Notchi, Nirnochi.
 Chemical constituents: Casticin, Isoorientin,
Chrysophenol D, Luteolin, P–hydroxyl benzoic acid
and D-fructose.
 Uses: It helps prevent grey hair. It lowers high body
temperature, fights infections, and strengthens
immunity due to its high vitamin C content and natural
antibiotic properties. Chaste tree leaves are boiled in
water, filtered and removed, and immediately Fig 3: Amla fruit
consumed to relieve heat.
 Habitat: Central India  Uses: Promote healthy hair growth, Boost volume,
 Propagation: Stem Cutting reduce dandruff, Treat head lice.
 Useful Part: Leave  Habitat: Uttar Pradesh Tamil Nadu, Rajasthan and
 Description: In India, Nirgundi is Ayurveda, folk, Madhya Pradesh in India
Siddha, Tibetan, Unani system Medicine (Udayan and  Propagation: Propagated by Shield budding
Indirabara Chandran, 2009; Vishwanathan and  Useful Part: Fruit, seeds, leaves, root, bark
Basavaraju, 2010). It's interesting that this isn't done  Description: Amla tree height grows up to 8 meter,
either with homeopathy and allopathic system

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Branchlets 10-20 cm long. Amla Leaves have pinnate Polysaccharides etc.

resemblance, very tiny, simple and attached by the base  Uses: Stop hair loss, make your hair look healthy and
to branchlets. Colors of flowers are yellowish. lustrous, prevent premature graying, thicken hair and
add volume, treat dandruff, Condition against frizz,
2.4 Brahmi [17, 18] Dryness, and breakage, Prevent split ends.
 Biological source: Leaves of Centella asiatica  Habitat: U.S, Europe, India
 Family: Apiaceae  Propagation: Stem Cutting
 Synonyms: Hydrocotyle asiatica  Useful Part: Flower
 Vernacular Name: Brahmi
 English Name: Asiatic Pennywort
 Hindi Name: Bemgsag, Brahma-Manduki, Gotukola,
Khulakhudi, Mandookaparni
 Ayurvedic Name: Mandukaparni
 Unani: Khulakudi
 Sidhha/Tamil: Babassa, Vallarai
 Chemical Constituents: Triterpenoids, Volatile and
Fatty acids, Alkaloids, Glycosides, Flavanoids, Others-
Vitamin B, C, G and some amino acids et
 Use: This herb helps in forming a protective layer
around the hair fibres.
 Habitat: India, China and Indonesia
 Propagation: Rooted sucker and seed
 Useful Part: Leave

Fig 5: Hibiscus flower

 Description: The leaves are alternate, ovate to

lanceolate, often with a toothed or lobed margin
(dentate). The flowers are large, conspicuous, trumpet-
shaped, with five or more petals, color from white to
pink, red, blue, orange, peach, yellow or purple, and
from 4–18 cm broad. Flower colour in certain species,
such as H. mutabilis and H. tiliaceus, changes with
age. The fruit is a dry five-lobed capsule, containing
several seeds in each lobe, which are released when the
capsule dehisces (splits open) at maturity. It is of red
and white colours. It is an example of complete flowers.

Fig 4: Brahmi leave 2.6 Neem [22, 23]

 Biological Source: Leaves of Azadirachta indica
 Description: Centella asiatica is known primarily as  Family: Meliaceae
"brain food" in India because it is one of the leading  Synonyms: Neem tree, Nim tree, Margosa, Arishth
herbs used to treat hair losses, skin problems, heal  Vernacular Name: Nim tree or Indian lilac
wounds, and activate nerves and brain cells. The leaves,  English Name: Neem tree, Bastard tree, Indian lilac
1-3 from each node of stems, long petioled, 2-6cm long  Hindi Name: Balnimb, Neem, Nim, Nimb, Veppam
and 1.5-5cm wide.  Ayurvedic Name: Arista, Nimbah, Picumarda
 Sidhha/Tamil: Vepa, Veppu,Vembu
2.5 Hibiscus [19-21]  Chemical Constituents: The most important active
 Biological source: Dried flowers of Hibiscus constituent is azadirachtin and the others are
Rosasinesis nimbolinin, nimbin, nimbidin, nimbidol, sodium
 Family: Malvaceae nimbinate, gedunin, salannin, and quercetin.
 Synonyms: Rosids, Malvales  Uses: Condition your scalp, promote healthy hair
 Vernacular Name: Chinese Rose growth, temporarily seal hair follicles, soothe frizz,
 English Name: Rosemallow minimize grays, reduce dandruff, Treat head lice.
 Hindi Name: Gudhal  Habitat: India, Pakistan, Bangladesh
 Ayurvedic Name: Japapushpa  Propagation: By neem seed germination, but you can
 Unani: Gurhal, Gudhal. also root shoot and root cuttings.
 Sidhha/Tamil: Semparuthi  Useful Part: Leave
 Chemical Constituents: Alkaloids, L-ascorbic acid,
Anthocyanin, Beta-carotene, Beta-sitosterol, Citric acid,

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2.7 Curry Leaves [24]

 Biological Source: It is the dried leaves of
Murraya koenigii
 Family: Rutaceae
 Synonyms: Mitholimdo
 Vernacular Name: Curry Leaf Tree, Daun Kari, Indian
Curry Tree
 English Name: Curry leaves
 Hindi Name: Curry patta, Meetha Neem, Kathnim
 Ayurvedic Name: Girinimba, Suravi
 Sidhha/Tamil: Karivempu, Karuveppilei, Karivepila
 Chemical Constituents: Volatile oil, the major
constituents identified were alpha-
Fig 6: Neem leaves pinene (51.7%), sabinene (10.5%), beta-pinene (9.8%),
beta-caryophyllene (5.5%), limonene
2.6.1 Description: It is evergreen tree with a height of (5.4%), bornyl acetate (1.8%), terpinen-4-ol (1.3%),
15 m (30 m maximum), having a large rounded crown gamma-terpinene (1.2%) and alpha-humulene (1.2%).
(10–20 m) with spreading branches and a branchless (5)
bole (7.5 m, diameter 90 cm). The bark of the tree is  Uses: Prevents hair fall and premature greying of hair,
thick, fissured, dark gray to red (inside) in color, and it Leprosy, eye problem, epistaxis, intestinal worms,
possesses a gummy colorless sap. The leaves are long anorexia, biliousness, skin ulcers.
(20–40 cm), alternate, pinnate, exstipulate, and glabrous  Habitat: Pakistan, Sri Lanka and India east to China
with a light green hue. The leaves have two pairs of and Hainan
basal glands with a subglabrous petiole (2–7 cm) and  Propagation: Cuttings or seed
above, channeled rachis. Each leaf comprises 8–19  Useful Part: Leave
serrated, proximally alternate, ovate to lanceolate
leaflets.

Fig 7: Curry leaves

 Description: Murraya koenigii is an unarmed, semi alternate, gland dotted and strongly aromatic. The stem
deciduous aromatic shrub or small tree with slender but of Murraya koenigii is an aromatic and more or less
strong woody stem and branches covered with dark deciduous shrub or small tree up to 7 meters in height
grey bark, leaves are imparipinnate, glabrous, and very and 14 to 42 cm in diameter.
strongly aromatic. Leaflets 9-25 or more, short stalked,

Almond oil Coconut oil Castor oil

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Cederwood oil Rosemary oil Lemon oil

2.7 Formulation literature Review maintaining good hair growth [36].

Herbal hair oil was prepared with the help of Amla,
Hibiscus, Brahmi and Methi. They have evaluated 3. Materials and Methods
parameters like specific gravity, pH, Refractive Index & 3.1 Collection of plant materials
Acid Value. The Result was found to be excellent hair The herbal hair oil was prepared by collecting various plant
growth activity [25-28]. materials like the fresh leaves of Curry, Henna, Neem,
Herbal hair oil Prepared to evaluating hair growth activity Nirgundi, Brahmi and Hibiscus flower from the garden,
with help of Embilica, Bacopa & more. They Evaluate Rajkot and purchase Cederwood oil and Rosemerry oil from
parameters like pH, Saponification Value, Physical taste and Dhanvantri Ayurvedic shop, Rajkot, Gujrat. It was
the results were found to be Various 3 Formulation Showed identified by Local Botanist working as an assistant. A
good and satisfied result for hair initiation and hair growth voucher specimen of all has been kept in our laboratory for
activity and also improvement in length of hair & its future reference. The leaves were shade dried, powdered
diameter [29, 30]. and sieved through 40 meshes, and then stored in a tightly
Herbal hair oil prepared by using herbal ingredients like, closed container for further use. Coconut oil in the mixture
Amla, Nirgundi, Jatamansi, Neem. They evaluated by was used as ideal base oil and Castor oil, Almond oil were
also used in mixture. The lemon oil was used to reduces
various parameters likes, pH, acid value. The Result were
dandruff. The oil works well as a hair tonic and can make
found to be herbal hair oil not only moisture scalp but also
your hair shinier and much stronger. The citric acid present
reverse dry scalp & dry hair condition [31].
in lemon oil prevents the hair follicles from getting loose,
Sometime hair oil prepared poly herbal hair oil by using thus reducing hair fall.
leech, hibiscus, onion, bee live, coconut oil like herbs and
the result were found to be the presence of natural 3.2 Preparation of herbal hair oil
ingredients, this formulation proves to be a boon to fight the Accurately weighed all the dried and fresh herbs and leaves
trending problems of hair fall due to various response [32]. powder was taken. Coconut oil, castor oil, Cederwood oil,
Few parameters were developed & evaluated of poly herbal Rosmery oil and almond oil were mixed. After that add
antidandruff hair oil by using various herbs like eucalypts henna powder, Amla powder were added and kept aside for
oil, ocimum oil, Hibiscus, Amla and tridax result found to overnight. Then curry leaves, neem powder were added and
be excellent hair growth stimulation [33-35]. Polyherbal Hair boiled until colour changes to dark brown colour. Small
oil was prepared by using different herbs like, curry leaves, amount of flavoring agent (lemon oil) was added to the
Banyan, Eclipta, Amla, Henna, Hibiscus, Vetives, oil and after whole preparation was filtered through muslin
Fenugreek and coconut oil and result was found to be cloth and filter paper. It was stored in tightly closed bottle.

Table 1: Formulation of herbal hair oil

Sr. No. Ingredients Quantity (for 180 ml oil)
1. Azadirachta indica J. Juss (Neem) 4.5 g
2. Murraya koenigii (Curry leaves) 4.5 g
3. Phyllanthus emblica Linn. (Amla) 9g
4. Lawsonia inermis (Henna) 3.6 g
5. vitex negundo (Nirgundi) 3.6 g
6. Centella asiatica L. (Brahmi) 12.9 g
7. Hibiscus rosasinensis (Hibiscus) 18 g
8. Cederwood oil 9 ml
9. Rosemerry oil 9 ml
10. Almond oil 3.6 ml
11. Coconut oil 64.8 ml
12. Castor oil 18 ml
13. Lemon oil 19.8 ml

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Fig 8: Chart of Herbal Hair Oil preparation

3.3 Evaluation of Herbal Hair Oil  The result was taken in triplicate.
 The formulated herbal oil was evaluated for parameters
like pH, acid value, saponification value, refractive 3.3.4 Specific gravity [43-45]
index, viscosity and organoleptic parameters. (38-41)  Specific gravity of the prepared oil was determined
using specific gravity bottle. The result was taken in
3.3.1 Saponification value triplicate.
 2g of oil was accurately weighed and transferred into a  The specific gravity of the solid is the ratio of its weight
250ml of iodine flask. 25ml of 0.5M alcoholic in air to the difference between its weight in air and its
potassium hydroxide was added and boiled under reflux weight immersed in water. Two methods are commonly
on a water bath for 30mins. Phenolphthalein was added used for determining the specific gravities of liquids.
as indicator and titrated against 0.5M HCl (‘a’ ml).
Similarly blank was performed (‘b’ ml) without the 3.3.5 Refractive index [45-50]
sample. The result was taken in triplicate.  It was determined using refractometer.
 Saponification Value: 28.05(b-a)/w Where, 1. Place the instrument in front of sodium light source or
 w= weight in grams of the solution. ordinary light source for measuring refractive index or
brix reading of sample.
3.3.2 pH 2. Look into eye piece (1) Focus into the eye piece upward
 pH of the herbal oil was detected using pH strip. and down ward, similarity focuses the scale eye piece
(2).
3.3.3 Viscosity 3. Adjust reflector to get desired light, now rotate the scale
 Viscosity was determined using Ostwald’s viscometer. knob (5) and look into the eye piece (2) and consider

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zero with the line. Now instrument is ready for testing distributors. 2001;639:641.
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2014;24(2):150-9.
Sr. No. Parameters Observation
1. Color Greenish Brown 13. Dinesh M, Roopan SM, Selvaraj CI. Photocatalytic
2. Odour Lemon Characteristic degradation of nitrophenol using biologically active
3. Specific gravity ±1.066 Phyllanthus emblica seed extract. J Photochem
4. pH ±6 Photobiol B. 2016;161:273-8.
5. Saponification value ±52.45 DOI: 10.1016/j.jphotobiol.2016.05.033, PMID
6. Irritancy test No Irritation 27288657.
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