The MSDS format adheres to the standards and regulatory requirements
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in other countries.
DuPont Page 1
Material Safety Data Sheet
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Niapure(R) Sodium Methylate 8-35% Solution
6228CR Revised 24-JUN-2003
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CHEMICAL PRODUCT/COMPANY IDENTIFICATION
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Material Identification
Niapure(R) is a registered trademark of DuPont.
# Tradenames and Synonyms
8% Sodium Methylate
15% Sodium Methylate
25% Sodium Methylate
30% Sodium Methylate
Sodium Methylate, 8% Solution in Methanol
Sodium Methylate, 15% Solution in Methanol
Sodium Methylate, 25% Solution in Methanol
Sodium Methylate, 30% Solution in Methanol
Sodium Methylate
Sodium Methoxide
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont Chemical Solutions Enterprise
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information : 1-800-441-7515
Transport Emergency : CHEMTREC 1-800-424-9300
Medical Emergency : 1-800-441-3637
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COMPOSITION/INFORMATION ON INGREDIENTS
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# Components
Material CAS Number %
Sodium Methylate 124-41-4 8-35
*Methyl Alcohol 67-56-1 65-92
* Disclosure as a toxic chemical is required under Section 313 of
Title III of the Superfund Amendments and Reauthorization Act of 1986
and 40 CFR part 372.
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Material Safety Data Sheet
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HAZARDS IDENTIFICATION
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Potential Health Effects
Skin contact can produce severe burns and ulceration of the
skin. Methanol can permeate the skin in amounts capable of
producing the effects of systemic toxicity.
Eye contact will result in eye corrosion or corneal or
conjunctival ulceration. Contact may result in permanent
damage to the eyes and even blindness.
Inhalation of concentrated mists, spray, or vapor may cause
severe damage to the upper respiratory tract.
Inhalation, ingestion or skin contact with methanol may
cause temporary mild depression of the central nervous
system with dizziness, confusion, incoordination or
drowsiness followed by an asymptomatic period usually
ranging from 12 to 24 hours. Metabolic acidosis develops
followed by occular toxicity (visual disturbances including
blindness). Other effects include non-specific effects such
as headache, nausea and weakness.
Ingestion can cause extreme burns to mucous membranes of the
mouth, throat, esophagus, and stomach. The fatal dose of
methanol by ingestion is from 60 to 250 ml.
Gross overexposure to methanol may cause pathological
changes in the liver and kidneys; nerve damage with
numbness, weakness or muscle rigidity; tremor; convulsions;
and fatality.
Carcinogenicity Information
None of the components present in this material at concentrations
equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH
as a carcinogen.
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FIRST AID MEASURES
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First Aid
INHALATION
If inhaled, remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen.
Call a physician.
SKIN CONTACT
In case of contact, immediately flush skin with plenty of water
for at least 15 minutes, while removing contaminated clothing and
shoes. Call a physician. Wash contaminated clothing before reuse.
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Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
EYE CONTACT
In case of contact, immediately flush eyes with plenty of water
for at least 15 minutes. Call a physician.
INGESTION
If swallowed, do not induce vomiting. Immediately give 2 glasses
of water, or activated charcoal mixture. Never give anything by
mouth to an unconscious person. Call a physician.
Notes to Physicians
Provide standard methanol ingestion treatment. Esophagoscopy may
be indicated. Intravenous administration of an ethanol solution
is an antidote for significant methanol ingestion. The blood
ethanol level should be in the range of 1-1.5 mg/mL.
Activated charcoal mixture may be administered. To prepare
activated charcoal mixture, suspend 50 grams activated charcoal in
400 mL water and mix thoroughly. Administer 5 mL/kg, or 350 mL
for an average adult.
NOTES TO PHYSICIAN
After ingestion, the patient may improve after the initial
crisis but perforation of the gastrointestinal tract may
occur 2-4 days later with severe abdominal pain, rigidity
and tenderness of the abdomen and shock. Weeks to months
later stricture of the esophagus may occur.
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FIRE FIGHTING MEASURES
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# Flammable Properties
Sodium Methylate:
Flash Point: 12 C (54 F)
Method: TCC
Flammable Limits in Air, % by Volume:
LEL: 7.3
UEL: 36
Autoignition: 470 C (878 F)
Methanol:
Flash Point: 52 F
Method: Closed Cup
Flammable Limits in Air, % by Volume:
LEL: 6
UEL: 36
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Material Safety Data Sheet
(FIRE FIGHTING MEASURES - Continued)
Flammable liquid. Vapor forms explosive mixture with air. Vapors
or gases may travel considerable distances to ignition source and
flash back.
Caution! This product is a corrosive liquid which can
explode. At ordinary temperatures, this product in methanol
vapor, when mixed with air is explosive within certain
limits. At high temperatures, which occur in open flames,
this product decomposes to produce hazardous products of
combustion.
Extinguishing Media
Water Spray, Foam, Dry Chemical, CO2.
Water may be ineffective in fighting fires of liquids with
low flash points, but water should be used to keep
fire-exposed containers cool.
Fire Fighting Instructions
Keep personnel removed and upwind of fire. Wear self-contained
breathing apparatus. Wear full protective equipment. Cool
tank/container with water spray.
If leak or spill has not ignited, use water spray to
disperse vapors and protect persons attempting to stop
leak.
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ACCIDENTAL RELEASE MEASURES
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Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Evacuate personnel, thoroughly ventilate area, use self-contained
breathing apparatus.
Initial Containment
Remove source of heat, sparks, flame, impact, friction or
electricity.
Spill Clean Up
Discarded material is a RCRA Hazardous Waste.
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Material Safety Data Sheet
(ACCIDENTAL RELEASE MEASURES - Continued)
Accidental Release Measures
Leaks should be stopped. Spills should be contained and
cleaned up immediately. Large spills should be blanketed
with alcohol foam to minimize fire hazards. Spills should be
soaked up with compatible absorbent materials which should
then be placed in approved containers, labeled, and stored
in a safe place out of doors to await proper disposal. The
spill area should then be flushed with water. All rinsate
should be removed and placed in approved containers to await
proper treatment or disposal. Spills on areas other than
pavement, e.g., dirt or sand, may be handled by removing the
affected soils and placing in approved containers. Vacuum
trucks should not be used due to electrical ignition hazard.
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HANDLING AND STORAGE
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Handling (Personnel)
Do not get in eyes, on skin, or on clothing. Avoid breathing
vapors or mist. Wash thoroughly after handling. Wash clothing
after use. Discard shoes if contaminated.
Handling (Physical Aspects)
Keep away from heat, sparks and flames.
Storage
Store in a well ventilated place. Store in a cool place. Keep
container tightly closed. Do not store with organic chemicals and
oxidizing agents.
Iron and steel are suitable metals for storage tanks.
Atmosphere tanks should be located at least 100 feet from
ignition sources, and pressure tanks at least 150 feet from
ignition sources. All tanks should be grounded. Each tank
should be equipped with a vent terminating outdoors and
protected by a flame arrester. Vents should be sized
according to the suggested Flammable Liquids Standard of
the NFPA or any local governing ordinances. Ventilation
should be provided.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Engineering Controls
Keep container tightly closed. Use only with adequate ventilation.
Avoid contact with organic chemicals and oxidizing agents
to avoid possible violent reaction.
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Material Safety Data Sheet
(EXPOSURE CONTROLS/PERSONAL PROTECTION - Continued)
Personal Protective Equipment
EYE/FACE PROTECTION
Wear coverall chemical splash goggles. Additionally, wear a face
shield where the possibility exists for face contact due to
splashing or spraying of material.
RESPIRATORS
Wear NIOSH approved respiratory protection, as appropriate.
PROTECTIVE CLOTHING
Where there is potential for skin contact have available,
and wear as appropriate, impervious gloves, apron, pants,
jacket or full chemical suit.
Exposure Guidelines
Applicable Exposure Limits
Methyl Alcohol
PEL (OSHA) : 200 ppm, 260 mg/m3, 8 Hr. TWA
TLV (ACGIH) : 200 ppm, 8 Hr. TWA, Skin
STEL 250 ppm
AEL * (DuPont) : 200 ppm, 8 & 12 Hr. TWA, Skin
* AEL is DuPont’s Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
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PHYSICAL AND CHEMICAL PROPERTIES
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# Physical Data
Boiling Point : 86.7 C (188.1 F) @ 760 mm Hg
Vapor Pressure : 96 mm Hg @ 20 C (68 F)
Vapor Density : 1.1 (Air = 1)
Freezing Point : -1.1 C (30 F)
Evaporation Rate : 5.9 (Butyl Acetate = 1)
Solubility in Water : Soluble
pH : ~12 for 2% solution
Odor : Alcohol odor
Form : Liquid
Color : Clear, water white
Specific Gravity : 0.95
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Material Safety Data Sheet
(PHYSICAL AND CHEMICAL PROPERTIES - Continued)
The above information pertains to a 25% solution.
For 8% Solution:
Boiling Point : 65.5 C
Vapor Pressure : 121.72 mm Hg @ 25 C
pH : ~10
Specific Gravity : 0.85
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STABILITY AND REACTIVITY
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Chemical Stability
Stable at normal temperatures and storage conditions.
Incompatibility with Other Materials
Avoid contacting this product with moisture, heat, sources
of ignition, organic chemicals and oxidizing agents.
Considerable heat is generated when water is added to this
product. This product reacts violently or explosively with
many organic chemicals and oxidizing agents.
Decomposition
This product will react with moisture in air to produce
sodium hydroxide, sodium carbonate and sodium formate. At
high temperatures this product in methanol will decompose
producing hazardous products of combustion including carbon
monoxide and formaldehyde.
Polymerization
Polymerization will not occur.
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TOXICOLOGICAL INFORMATION
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Animal Data
METHANOL
Inhalation 1 hour LC50: >145,000 ppm in rats
Dermal LD50 : 15,840 mg/kg in rabbits
Oral LD50 : 9100 mg/kg in rats
Animal testing indicates Methyl alcohol is an eye and skin
irritant.
Eye contact with Methyl alcohol caused clouding of the eye
(corneal opacity).
Repeated skin contact with higher concentrations of Methyl
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Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
alcohol caused some mortality.
Single exposure by ingestion caused narcosis, liver effects
and hypothermia. Repeated exposure caused pathological
changes of the eyes and acidosis.
Exposure of pregnant rats resulted in reduced birth weight,
bone abnormalities and behavioral abnormalities. Exposure of
pregnant mice resulted in reduced birth weight, resorption
and bone abnormalities. Tests have shown that Methyl alcohol
does not cause genetic damage in bacterial or mammalian
cell cultures or in animals.
No adequate animal data are available to define reproductive
toxicity.
SODIUM METHYLATE
Oral LD50: 2037 mg/kg in rats
Because of the compound’s known corrosivity in humans, it is
untested for skin and eye irritancy, and for animal
sensitization. Repeated oral dosing produced nonspecific
effects such as weight loss, and irritation.
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ECOLOGICAL INFORMATION
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Ecotoxicological Information
Aquatic Toxicity
96 hour LC50, fathead minnow: 28,100 mg/L for methanol
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DISPOSAL CONSIDERATIONS
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Waste Disposal
Treatment, storage, transportation, and disposal must be in
accordance with applicable Federal, State/Provincial, and Local
regulations.
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TRANSPORTATION INFORMATION
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Shipping Information
DOT/IMO/IATA
Proper Shipping Name : Sodium Methylate Solution
Hazard Class : 3
UN No. : 1289
Packing Group : II
Subsidiary Hazard Class : 8
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Material Safety Data Sheet
(TRANSPORTATION INFORMATION - Continued)
Reportable quantity : 1000 lbs. (Sodium Methylate); 5000 lbs.
(Methyl Alcohol)
Label(s) : Flammable Liquid, Corrosive
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REGULATORY INFORMATION
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U.S. Federal Regulations
TSCA Inventory Status : Reported/Included.
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : Yes
Fire : Yes
Reactivity : Yes
Pressure : No
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OTHER INFORMATION
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NFPA, NPCA-HMIS
NPCA-HMIS Rating
Health : 3
Flammability : 4
Reactivity : 2
Personal Protection rating to be supplied by user depending on use
conditions.
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The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsible for MSDS : MSDS Coordinator
> : DuPont Chemical Solutions Enterprise
Address : Wilmington, DE 19898
Telephone : (800) 441-7515
# Indicates updated section.
This information is based upon technical information believed to be
reliable. It is subject to revision as additional knowledge and
experience is gained.
End of MSDS
Print Date: 3 - 23 - 2006
