Lovely Professional University,Punjab
Format For Instruction Plan [for Courses with Lectures and Labs
Course No PHR420T
Cours Title MEDICINAL CHEMISTRY-III
Course Planner 13522 :: Nipun Mahajan
Lectures Tutorial Practical Credits 3 0 0 3
Text Book:
1 Principles of Medicinal Chemistry William O. Foye, Thomas L. Lemke, David A. Williams Lippincott Williams & Wilkins, 2007
Other Specific Book:
Medicinal and Pharmaceutical chemistry, by Harikrishan singh & [Link] ; Vallab Prakshan, First edition.
3 The organic Chemistry of Drug Design and Drug Action, Richard B. Silverman, Academic Press, 2004 4 Wilson and Gisvold's textbook of organic Medicinal and Pharmaceutical chemistry, Charles Owens Wilson, John H. Block, Ole Gisvold, John Marlowe Beale, Lippincott Williams & Wilkins, 2004
Other Reading Sr No Jouranls atricles as compulsary readings (specific articles, Complete reference) 5 Bhosle, D. Bharambe S., Gairola Neha, Suneela S, Dhaneshwar. Mutual prodrug concept: fundamentals and applications Indian journal of pharmaceutical Sciences. 2006, 68 (3); 286-294 6 Selvam P., Murgesh N., Chandramohan M., Debyser Z., Design, synthesis and anti HIV activity of novel Isatine-Sulphoanmides Indian J. Pharm. Sci., 2008,70 (6) : 779-782 7 Triphati Laxmi, Kumar Parveen Singhai Role of chelates in treatment of cancer 44 (2) 62-72 Relevant Websites Sr. No. (Web adress) (only if relevant to the courses) 8 [Link] Salient Features Active antifungal substances from natural sources
Detailed Plan For Lectures
Approved for Spring Session 2011-12
Week Number Lecture Number Lecture Topic
Chapters/Sections of Pedagogical tool Textbook/other Demonstration/case reference study/images/anmatio n ctc. planned
Part 1
Week 1 Lecture 1 Drug metabolism ->Reference :4,Ch-4/142 ->Reference :1,Ch-10/253 ->Reference :4,Ch-4/142 ->Reference :1,Ch-10/253 ->Reference :4,Ch-4/144 ->Reference :5,286294 ->Reference :1,Ch-10/253 ->Reference :4,Ch-4/144 ->Reference :5,286294 ->Reference :5,286294 ->Reference :4,Ch-4/150-155 ->Reference :4,Ch-8/223 ->Reference :3,Ch-2/34 ->Reference :4,Ch-8/223 ->Reference :3,Ch-2/34 ->Reference :4,Ch-8/155 ->Reference :3,Ch-2/34 ->Reference :2,Ch35/867 Approved for Spring Session 2011-12 videos videos
Lecture 2
Drug metabolism
Lecture 3
Concepts of Prodrugs
Week 2
Lecture 4
Prodrugs of functional groups
Lecture 5
Bioprecursors Prodrugs and Chemical diversity Prodrugs
Lecture 6
Antimetabolites-oxidising agents
Week 3
Lecture 7
Antimetabolites-Cationic surfactants, Mercurials, Nucleosides analogs
model
Lecture 8
Antimetabolites-Dermatophytoses
Lecture 9
Antiprotozoal
Week 4
Lecture 10
Antiviral-anti-HIV drugs
->Reference :2,Ch-39/952 ->Reference :7,62-72
model
Part 2
Week 4 Lecture 11 Antifungal Nucleosides antifungals ->Reference :4,Ch-8/230 ->Reference :8 ->Reference :4,Ch-8/233 ->Reference :1,Ch-39/1084 ->Reference :4,Ch-38/929 ->Reference :1,Ch-42/1147 ->Reference :4,Ch-38/929 ->Reference :1,Ch-42/1147 ->Reference :1,Ch-27/323 ->Reference :4,Ch-30/718 ->Reference :1,Ch-27/323 ->Reference :4,Ch-30/718 ->Reference :1,Ch26/315 ->Reference :1,Ch26/315 ->Reference :1,Ch26/315 ->Reference :4,Ch-6/114 ->Reference :6,779782 ->Reference :4,Ch-6/116 ->Reference :6,779782 Approved for Spring Session 2011-12 Videos PPT videos
Lecture 12
Antiparasitics
model
Week 5
Lecture 13
Antineoplastics -Alkylating agents, nitrosoureas, antimetabolites
PPt
Lecture 14
Antineoplastic antitumor antibiotics, antimitotic agents
PPT
Lecture 15
Thyroid drugs
Week 6
Lecture 16
Antithyriod drugs
Lecture 17 Lecture 18 Week 7 Lecture 19 Lecture 20
Insulin oral hypoglycaemic agents Oral hypoglycaemic agents Peptidomimetics
Lecture 21
Nucleomimetics
MID-TERM Part 3
Week 8 Lecture 22 Lecture 23 Lecture 24 Week 9 Lecture 25 Lecture 26 Lecture 27 Week 10 Lecture 28 Lecture 29 Diagnostic agents Radiographic contrast media Diagnostic agents-dyes, inulin ->Reference :1,Ch-43 ->Reference :1,Ch-43 ->Reference :1,Ch-43 ->Reference :1,Ch-43 Videos PPT
Diagnostic agents-Histamine phosphate and related ->Reference :1,Ch-43 compounds Pharmaceutical aids-preservatives Pharmaceutical aids-antioxidants Pharmaceutical aids-colouring agents ->Reference :1,Ch-46 ->Reference :1,Ch-46 ->Reference :1,Ch-46
Animations
Part 4
Week 10 Week 11 Lecture 30 Lecture 31 Lecture 32 Lecture 33 Week 12 Lecture 34 Lecture 35 Lecture 36 Week 13 Lecture 37 Lecture 38 Lecture 39 flavouring agents Pharmaceutical aids- sweetening agents Emulsifying agents Ointment bases solvents Vehicles Immunostimulants Immunostimulants Immunosuppressants Immunosuppressants ->Reference :1,Ch-46 ->Reference :1,Ch-46 ->Reference :1,Ch-46 ->Reference :1,Ch-46 ->Reference :1,Ch-46 ->Reference :1,Ch-46 ->Reference :1,Ch-46 ->Reference :1,Ch-46 ->Reference :1,Ch-46 ->Reference :1,Ch-46 animations animations Pharmaceutical prepreations
Spill Over
Week 14 Lecture 40 Lecture 41 Thyroid drugs Antiparasitics ->Reference :1,Ch27/323 ->Reference :4,Ch8/233
Approved for Spring Session 2011-12
Approved for Spring Session 2011-12
