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Cream Base

cream

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jaimurugesh
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0% found this document useful (0 votes)
713 views2 pages

Cream Base

cream

Uploaded by

jaimurugesh
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

Cream base

[Link] Items Qty %


1 Cetostearyl alcohol 8%
2 Cetomacrogol 2%
3 Paraffin wax 2.5 %
4 Microwax 1.5 %
5 Light liquid paraffin 10 %
6 Water 70 %
7 Propylene glycol 6%

INGREDIENTS SPECIFICATION QUANTITY in % Function


w/w
Betamethasone BP 0.105 Active drug
valerate

Chlorocresol BP 0.100 Preservative

Cetomacrogal BP 2.0 Emulsifier

Cetostearyl alcohol BP 8.0 Emulsifier

White soft paraffin BP 15.33 Oil phase

BP Emollient
Propylene glycol 5.86
BP

Purified water BP 68.60 Aqueous phase


Polyethylene glycol ointment

PEG 4000 40 G

PEG 400 60 G

Melt both items at 600c allow to cool,and stir until congealed.

For firmer preparation

PEG 4000 50 G

PEG 400 50 G

If 6 to 25% aqueous items to be incorporated

PEG 4000 35 G

PEG 400 60 G

Stearyl alcocol 5G

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