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Pharmaceutical Calculations Quiz

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0% found this document useful (0 votes)
232 views7 pages

Pharmaceutical Calculations Quiz

Uploaded by

Raph jairi
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

Question 1

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What volume of a 100 mcg/5 mL solution is required to administer a 0.5 mg dose?
Select one:
A. 25 mL
B. 2.5 mL
C. 200 microlitres
D. 100 Ml
0.1 mg 0.5 mg
= → 25 mL
5 mL x mL
Question 2
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How many hours can be administered at a rate of 200 mg/hr if you have 500 mL of a 2% w/v magnesium
sulfate solution?
Select one:
A. 50 hours
B. 20 hours
C. 5 hours
D. 2 hours
2g 1 hr 1000 mg
x 500 ml x x =50 hrs
100 ml 200 mg 1g
Question 3
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How many grams of magnesium sulfate are in 2 mL of a 50% w/v magnesium sulfate solution?
Select one:
A. 0.5 g
B. 1 g
C. 2 g
D. 0.5 mg
50 g
x 2 mL=1 g
100 mL
Question 4
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Calculate the molarity (moles/L or M) of a solution if it contains 28 g of sodium bicarbonate in 1 L of
solution (molecular weight of sodium bicarbonate 84):
Select one:
A. 3.0 M
B. 0.33 M
C. 33 M
D. 0.03 M
28 g
84 g
mol
=¿
1L
Question 5
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How many grams of azathioprine (molecular weight = 277.3) contain 15 mmol of drug?
Select one:
A. 277.3 g
B. 416 mg
C. 4.16 g
D. 18.5 g
g 1000 mg 15 mmolx 277.3
15 mmol= x = =4.155 ≈ 4.16 g
MW g 1000
Question 6
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3 g of lidocaine in 250 mL of 5% dextrose in water is charted at an infusion rate of 120 mg/hr. Calculate
the infusion rate in mL/hr.
Select one:
A. 5 mL/hr
B. 120 mL/hr
C. 25 mL/hr
D. 10 mL/hr
250 ml 1g 120 mg 10 ml
x x =
3g 1000 mg hr hr
Question 7
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If the standard infusion rate of Drug B is 0.25 mg/kg/hr, how many mL/min will be administered to a
patient weighing 60 kg? (Drug B 250 mL infusion bag 0.2 mg/mL).
Select one:
A. 25 mL
B. 2.5 mL
C. 1.25 mL
D. 125 mL
0.25 mg 1 ml 1 hr
60 kg x x x =1.25 mL
kg 0.2 mg 60 min
hr
Question 8
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Patient HA weighs 68 kg. The doctor has ordered a single dose of 2 mg/kg of Drug Y. This medication is
provided as 80 mg in 2 mL. Calculate the volume required.
Select one:
A. 2.8 mL
B. 1.6 mL
C. 3.0 mL
D. 3.4 mL
2 mg 2 mL
68 kg x x =3.4 mL
kg 80 mg
Question 9
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A patient has been prescribed Drug X at an infusion rate of 0.72 mg/min. The pharmacy has infusion bags
containing Drug X 2 g in 1 litre. What rate in mL/hr should the infusion be set to run at?
Select one:
A. 7.2 mL/hr
B. 86.4 mL/hr
C. 21.6 mL/hr
D. 43.2 mL/hr
0.7 2 mg 1000 mL 60 min
x x =21.6 mL
min 2000 mg hr
Question 10
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A 63-year-old male is admitted who weighs 70 kg and his serum creatinine is 280 micromol/L. What SC
dose of enoxaparin is required, to treat venous thrombosis? The dose for a patient with normal renal
function is 1.5 mg/kg once daily, for patients with CrCl <30 mL/min, the dose is 1 mg/kg SC once daily.
Select one:
A. 94.5 mg
B. 63 mg
C. 105 mg
D. 70 mg
CF = 88.42 (mg/dL  umol/L)
(140− Age ) x kg ( 140−63 ) x 70
CrCl= → =23.64 CrCl
mg 280
x 72 x 72
dL 88.42
1 mg
70 kg x =70 mg
kg
Question 11
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An 80-year-old male is admitted who weighs 58 kg and his serum creatinine is 180 micromol/L. What IV
loading dose (6-hourly) of digoxin is required. The dose for a patient with normal renal function is 250
micrograms IV, 6-hourly, for patients with CrCl <60 mL/min, 50% of the usual loading dose should be
given.
Select one:
A. 125 mcg
B. 1000 mcg
C. 500 mcg
D. 250 mcg
CF = 88.42 (mg/dL  umol/L)
(140− Age ) x kg ( 140−80 ) x 58
CrCl= → =23. 7 4 CrCl
mg 1 80
x 72 x 72
dL 88.42
250 mcg
x 4=500 mcg
2

Question 12
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How many 10 mg tablets do you need to dispense to provide a patient (body surface area 1.78 m2) with
drug X 22.5 mg/m2 TDS for 1 week?
Select one:
A. 28
B. 21
C. 4
D. 84
2
1.78 m 23.15 mgx 7 x 3
2
x 22.5 mg= =48.6 ≈ 49
1.73 m 10

Question 13
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Calculate the dose in g/mL if 3 mg/kg/mL has been prescribed, using the ideal body weight for a 178 cm
female of average build.
Select one:
A. 0.21
B. 220.2
C. 2.10
D. 206.7

3 mg∗ml 1g g
71 kg x x =0.213
kg 1000 mg mL
Question 14
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After a 5 mg IV dose, the blood concentration result was 22 micrograms/mL. What is the apparent volume
of distribution for the drug?
Select one:
A. 1.15 L
B. 4.40 L
C. 2.30 L
D. 0.23 L
0.022 mg
Cp mL
Vd= = x 1000
Dose 5 mg
Question 15
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Calculate the half-life for a drug that has an elimination rate constant of 0.0147 min-1, if it follows first
order kinetics.
Select one:
A. 47 min
B. 59 min
C. 23 min
D. 10 min
ln 2 ln 2
t 1/ 2= = =47.15 mins
k 0.0147
mi
Question 16
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Calculate the volume required per dose if cefaclor 10 mg/kg 8 hourly has been prescribed for a child
weighing 17 kg. Cefaclor is available in 250 mg/5 mL bottles.
Select one:
A. 10.2 mL
B. 170 mL
C. 510 mg
D. 3.4 mL
10 mg 5 mL
17 kg x x =3.4 mL
kg 250 mg
Question 17
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A 3-year-old child, weighing 18.5 kg has been prescribed erythromycin 200 mg/5 mL TDS. Calculate the
volume per dose, if the recommendation for erythromycin is 15 mg/kg.
Select one:
A. 12 mL
B. 20 mL
C. 7.2 mL
D. 6.9 mL
15 mg 5 mL
18.5 kg x x x 3=20.81mL
kg 200 mg
Question 18
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What is the final concentration if 60 mL of a 1 in 10 solution is diluted to 200 mL?
Select one:
A. 0.3%
B. 3.0%
C. 33.3%
D. 0.03%
C 1 V 1=C 2 V 2

( 101 x 100) ( 60 mL )=C 2 ( 200 mL ) → C 2=3 %


Question 19
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Calculate the amount of salicylic acid that must be added to 50 g of a 1.5% w/w ointment to produce a 4%
w/w ointment.
Select one:
A. 4.0 g
B. 1.3 g
C. 2.5 g
D. 0.5 g

100 2.5  x g
4
1.5 96  50 g
2.5 96
= → 1.3 g
x 50

Question 20
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What is the final concentration if 100 mL of a 20% w/v solution is diluted to 250 mL with water?
Select one:
A. 10% w/v
B. 0.08% w/v
C. 8% w/v
D. 50% w/v
C 1 V 1=C 2 V 2
( 20 % )( 100 mL )=C 2 ( 2 50 mL ) → C 2=8 %

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