Question 1
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What volume of a 100 mcg/5 mL solution is required to administer a 0.5 mg dose?
Select one:
A. 25 mL
B. 2.5 mL
C. 200 microlitres
D. 100 Ml
0.1 mg 0.5 mg
= → 25 mL
5 mL x mL
Question 2
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How many hours can be administered at a rate of 200 mg/hr if you have 500 mL of a 2% w/v magnesium
sulfate solution?
Select one:
A. 50 hours
B. 20 hours
C. 5 hours
D. 2 hours
2g 1 hr 1000 mg
x 500 ml x x =50 hrs
100 ml 200 mg 1g
Question 3
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How many grams of magnesium sulfate are in 2 mL of a 50% w/v magnesium sulfate solution?
Select one:
A. 0.5 g
B. 1 g
C. 2 g
D. 0.5 mg
50 g
x 2 mL=1 g
100 mL
Question 4
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Calculate the molarity (moles/L or M) of a solution if it contains 28 g of sodium bicarbonate in 1 L of
solution (molecular weight of sodium bicarbonate 84):
Select one:
A. 3.0 M
B. 0.33 M
C. 33 M
D. 0.03 M
28 g
84 g
mol
=¿
1L
Question 5
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How many grams of azathioprine (molecular weight = 277.3) contain 15 mmol of drug?
Select one:
A. 277.3 g
B. 416 mg
C. 4.16 g
D. 18.5 g
g 1000 mg 15 mmolx 277.3
15 mmol= x = =4.155 ≈ 4.16 g
MW g 1000
Question 6
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3 g of lidocaine in 250 mL of 5% dextrose in water is charted at an infusion rate of 120 mg/hr. Calculate
the infusion rate in mL/hr.
Select one:
A. 5 mL/hr
B. 120 mL/hr
C. 25 mL/hr
D. 10 mL/hr
250 ml 1g 120 mg 10 ml
x x =
3g 1000 mg hr hr
Question 7
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If the standard infusion rate of Drug B is 0.25 mg/kg/hr, how many mL/min will be administered to a
patient weighing 60 kg? (Drug B 250 mL infusion bag 0.2 mg/mL).
Select one:
A. 25 mL
B. 2.5 mL
C. 1.25 mL
D. 125 mL
0.25 mg 1 ml 1 hr
60 kg x x x =1.25 mL
kg 0.2 mg 60 min
hr
Question 8
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Patient HA weighs 68 kg. The doctor has ordered a single dose of 2 mg/kg of Drug Y. This medication is
provided as 80 mg in 2 mL. Calculate the volume required.
Select one:
A. 2.8 mL
B. 1.6 mL
C. 3.0 mL
D. 3.4 mL
2 mg 2 mL
68 kg x x =3.4 mL
kg 80 mg
Question 9
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A patient has been prescribed Drug X at an infusion rate of 0.72 mg/min. The pharmacy has infusion bags
containing Drug X 2 g in 1 litre. What rate in mL/hr should the infusion be set to run at?
Select one:
A. 7.2 mL/hr
B. 86.4 mL/hr
C. 21.6 mL/hr
D. 43.2 mL/hr
0.7 2 mg 1000 mL 60 min
x x =21.6 mL
min 2000 mg hr
Question 10
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A 63-year-old male is admitted who weighs 70 kg and his serum creatinine is 280 micromol/L. What SC
dose of enoxaparin is required, to treat venous thrombosis? The dose for a patient with normal renal
function is 1.5 mg/kg once daily, for patients with CrCl <30 mL/min, the dose is 1 mg/kg SC once daily.
Select one:
A. 94.5 mg
B. 63 mg
C. 105 mg
D. 70 mg
CF = 88.42 (mg/dL umol/L)
(140− Age ) x kg ( 140−63 ) x 70
CrCl= → =23.64 CrCl
mg 280
x 72 x 72
dL 88.42
1 mg
70 kg x =70 mg
kg
Question 11
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An 80-year-old male is admitted who weighs 58 kg and his serum creatinine is 180 micromol/L. What IV
loading dose (6-hourly) of digoxin is required. The dose for a patient with normal renal function is 250
micrograms IV, 6-hourly, for patients with CrCl <60 mL/min, 50% of the usual loading dose should be
given.
Select one:
A. 125 mcg
B. 1000 mcg
C. 500 mcg
D. 250 mcg
CF = 88.42 (mg/dL umol/L)
(140− Age ) x kg ( 140−80 ) x 58
CrCl= → =23. 7 4 CrCl
mg 1 80
x 72 x 72
dL 88.42
250 mcg
x 4=500 mcg
2
Question 12
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How many 10 mg tablets do you need to dispense to provide a patient (body surface area 1.78 m2) with
drug X 22.5 mg/m2 TDS for 1 week?
Select one:
A. 28
B. 21
C. 4
D. 84
2
1.78 m 23.15 mgx 7 x 3
2
x 22.5 mg= =48.6 ≈ 49
1.73 m 10
Question 13
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Calculate the dose in g/mL if 3 mg/kg/mL has been prescribed, using the ideal body weight for a 178 cm
female of average build.
Select one:
A. 0.21
B. 220.2
C. 2.10
D. 206.7
3 mg∗ml 1g g
71 kg x x =0.213
kg 1000 mg mL
Question 14
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After a 5 mg IV dose, the blood concentration result was 22 micrograms/mL. What is the apparent volume
of distribution for the drug?
Select one:
A. 1.15 L
B. 4.40 L
C. 2.30 L
D. 0.23 L
0.022 mg
Cp mL
Vd= = x 1000
Dose 5 mg
Question 15
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Calculate the half-life for a drug that has an elimination rate constant of 0.0147 min-1, if it follows first
order kinetics.
Select one:
A. 47 min
B. 59 min
C. 23 min
D. 10 min
ln 2 ln 2
t 1/ 2= = =47.15 mins
k 0.0147
mi
Question 16
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Calculate the volume required per dose if cefaclor 10 mg/kg 8 hourly has been prescribed for a child
weighing 17 kg. Cefaclor is available in 250 mg/5 mL bottles.
Select one:
A. 10.2 mL
B. 170 mL
C. 510 mg
D. 3.4 mL
10 mg 5 mL
17 kg x x =3.4 mL
kg 250 mg
Question 17
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A 3-year-old child, weighing 18.5 kg has been prescribed erythromycin 200 mg/5 mL TDS. Calculate the
volume per dose, if the recommendation for erythromycin is 15 mg/kg.
Select one:
A. 12 mL
B. 20 mL
C. 7.2 mL
D. 6.9 mL
15 mg 5 mL
18.5 kg x x x 3=20.81mL
kg 200 mg
Question 18
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What is the final concentration if 60 mL of a 1 in 10 solution is diluted to 200 mL?
Select one:
A. 0.3%
B. 3.0%
C. 33.3%
D. 0.03%
C 1 V 1=C 2 V 2
( 101 x 100) ( 60 mL )=C 2 ( 200 mL ) → C 2=3 %
Question 19
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Calculate the amount of salicylic acid that must be added to 50 g of a 1.5% w/w ointment to produce a 4%
w/w ointment.
Select one:
A. 4.0 g
B. 1.3 g
C. 2.5 g
D. 0.5 g
100 2.5 x g
4
1.5 96 50 g
2.5 96
= → 1.3 g
x 50
Question 20
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What is the final concentration if 100 mL of a 20% w/v solution is diluted to 250 mL with water?
Select one:
A. 10% w/v
B. 0.08% w/v
C. 8% w/v
D. 50% w/v
C 1 V 1=C 2 V 2
( 20 % )( 100 mL )=C 2 ( 2 50 mL ) → C 2=8 %