Seat No.: _____ Enrolment No.

_____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph. - SEMESTER– III • EXAMINATION – WINTER -2023

Subject Code:BP304TT Date: 18/01/2024

Subject Name: Pathophysiology
Time: 10:30 AM TO 1:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Explain the various mechanisms of pathogenesis of cell injury. 06

(b) Discuss etiology and pathophysiology of congestive heart failure. 05
(c) Discuss the pathogenesis of asthma. 05
Q.2 (a) Describe the risk factors, symptoms and pathogenesis of peptic ulcer. 06
(b) Describe the symptoms and pathophysiology of acute renal failure. 05
(c) Discuss the symptoms, etiology and diagnosis of diabetes mellitus. 05
Q.3 (a) Discuss the symptoms, pathogenesis and treatment of depression. 06
(b) Discuss the etiological factors and diagnosis of ulcerative colitis. 05
(c) Write the pathophysiology of rheumatoid arthritis. 05
Q.4 (a) Discuss the risk factors, diagnosis and pathogenesis of cancer. 06
(b) Explain the symptoms, etiology and diagnosis of Tuberculosis. 05
(c) Discuss the sign, symptoms and complications of urinary tract infections. 05
Q.5 (a) Write mechanisms of different types of inflammation. 06
(b) Discuss the pathophysiology of AIDS. 05
(c) Write etiological factors and pathophysiology of hypertension. 05
Q. 6 (a) Define Homeostasis. Explain the regulatory mechanisms of homeostasis. 06
(b) Enlist various types of anemia and write a note on sickle cell anemia. 05
(c) Write sign, symptoms and pathophysiology of Alzheimer’s disease. 05
Q.7 (a) Describe the etiology, pathogenesis and diagnosis of atherosclerosis. 06
(b) Describe the etiology and pathophysiology of hyperthyroidism. 05
(c) Discuss the sign, symptoms and diagnosis of osteoporosis. 05

***************
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B. Pharm. – SEMESTER–3 EXAMINATION – WINTER -2022

Subject Code: BP304TT Date: 20/02/2023

Subject Name: Pathophysiology
Time: 10:30AM TO 01:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define inflammation. Explain vascular and cellular events of acute 06
inflammation.
(b) Discuss the pathogenesis and clinical manifestation of Tuberculosis. 05
(c) Explain the pathophysiology of inflammatory bowel disease 05
Q.2 (a) Enlist the chemical mediators of inflammation. Explain the role of arachidonic 06
acid metabolites in inflammation.
(b) Discuss symptoms and pathogenesis of peptic ulcer 05
(c) Write etiology and pathogenesis of Parkinson’s disease 05
Q.3 (a) What is atherosclerosis? Explain the pathogenesis of atherosclerosis. 06
(b) Write signs, symptoms and etiopathogenesis of Alzheimer’s disease 05
(c) Define apoptosis. Write in detail about the mechanism of apoptosis 05
Q.4 (a) Define cancer. Discuss carcinogenesis in detail. 06
(b) Explain clinical features and stages of chronic renal failure 05
(c) Discuss stages and pathogenesis of AIDS 05
Q.5 (a) What is anemia? Enlist different types of anemia. Explain in detail sickle cell 06
anemia.
(b) Define homeostasis, emphysema, hemophilia, atrophy and gout. 05
(c) Define Ischemic heart disease? Discuss different types of angina pectoris. 05
Q. 6 (a) Define diabetes mellitus. Enlist complications of diabetes and describe any two 06
in detail.
(b) Describe the etiology and pathogenesis of congestive cardiac failure. 05
(c) Describe the immunopathogenesis of rheumatoid arthritis. Write the differences 05
between rheumatoid arthritis and osteoarthritis.
Q.7 (a) Define epilepsy. Explain the clinical features of different types of epilepsy 06
(b) Explain different types of leprosy. 05
(c) Discuss clinical features and pathogenesis of asthma. 05

***************
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Pharm. - SEMESTER–III • EXAMINATION – WINTER -2021

Subject Code:BP304TT Date: 21/02/2022

Subject Name: Pathophysiology
Time: 10:30AM to 01:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Write pathophysiology of Peptic Ulcer Disease and its complications. 06
(b) Define apoptosis. Write in detail about mechanism of apoptosis. 05
(c) Write a note on urinary tract infection. 05
Q.2 (a) Describe different type of inflammation with its mechanism. 06
(b) What is blood pressure? Write parthophysiology of hypertension. 05
(c) Write pathophysiology of asthma and its complication. 05
Q.3 (a) Write features of acute and chronic renal failure. 06

(b) Classify Diabetes, Explain etiology,pathophysiology and diagnosis. 05

(c) Write sign, symptoms and pathophysiology of alzeimer’s disease. 05
Q.4 (a) Write a note on disorder of sex hormone. 06
(b) Enumerate various type of Anemia and Explain megaloblastic anemia. 05
(c) Write pathophysiology of inflammatory bowel disease and its diagnosis. 05
Q.5 (a) Classify Gout and explain pathophysiology and treatment. 06
(b) Write a note on cancer. 05
(c) Write stages, Diagnosis, Pathogenesis and treatment of HIV. 05
Q. 6 (a) Write sign,symptoms,etiology,diagnosis and treatment of tuberculosis. 06
(b) Describe mediators of inflammation. 05
(c) Explain the following terms: 05
1) hypertrophy 2) hyperplasia 3) systemis lupus erythromatous
4) hyperplasia 5) necrosis
Q.7 (a) Write in detail about causes of cell injury. 06
(b) Give pathogenesis and diagnosis of atherosclerosis. 05
(c) Explain sequence of events in wound healing by secondary union process. 05

***************
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph- SEMESTER–III • EXAMINATION – WINTER -2020

Subject Code: BP304TT Date: 24/02/2021

Subject Name: Pathophysiology
Time: 02:30PM TO 04:30PM Total Marks: 54
Instructions:
1. Attempt any THREE questions from Q-1 to Q-6.
2. Q.7 is compulsory to attempt.
3. Make suitable assumptions wherever necessary.
4. Figures to the right indicate full marks.

Q.1 (a) Enumerate cellular adaptations. Discuss physiological and pathological atrophy. 06
(b) Enumerate inflammatory cells. Discuss their role in inflammation. 05
(c) Explain life cycle of malarial parasite. 05
Q.2 (a) Define atherosclerosis. Discuss etiological factors and pathogenesis of 06
atherosclerosis.
(b) What is inflammatory bowel disease? Write etiological factors, symptoms and 05
diagnosis of ulcerative colitis.
(c) Write a note on acute renal failure. 05
Q.3 (a) Discuss risk factors, pathogenesis, diagnosis and complications of type-2 06
diabetes mellitus.
(b) Write symptoms and pathophysiology of Parkinson disease. 05
(c) Describe various causes of cell injury. 05
Q.4 (a) Discuss risk factors, symptoms, diagnosis and pathogenesis of asthma. 06
(b) Write etiological factors and pathophysiology of hypertension. 05
(c) Define homeostasis. Explain regulatory mechanism of homeostasis. 05
Q.5 (a) Describe risk factors, symptoms and pathogenesis of peptic ulcer. 06
(b) Write in brief pathogenesis of Gout and Arthritis. 05
(c) Write a note on hepatitis B. 05
Q. 6 (a) What is depression? Explain symptoms and pathogenesis of depression. 06
(b) Write in brief pathogenesis of syphilis and AIDS. 05
(c) Write a note on hyperthyroidism. 05
Q.7 (a) Define and classify anemia. Write a note on thalassemia. 06
OR
(a) Explain etiology and general pathogenesis of tumor formation. 06
OR
(a) Write a note on meningitis. 06

***************
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER– 3 EXAMINATION – WINTER -2019

Subject Code: BP304TT Date: 21-11-2019

Subject Name: Pathophysiology
Time: 10:30AM TO 01:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Classify types of hypertension. Write a note on risk factors and management of 06
hypertension
(b) Write signs and symptoms and complications of Diabetes mellitus. 05
(c) Define Atrophy, Hypertrophy, Hyperplasia, Metaplasia and Dysplasia 05
Q.2 (a) Explain pathophysiology of Peptic ulcer diseases. 06
(b) Explain the pathogenesis of asthma. Write differences between Bronchial 05
asthma and COPD.
(c) Explain diagnosis and management of Tuberculosis. 05
Q.3 (a) Write pathophysiology of Rheumatoid arthritis. 06
(b) Explain causes of acute renal failure. 05
(c) Describe the signs and symptoms of various forms of epilepsy. 05
Q.4 (a) Write clinical manifestation and pathophysiology of Parkinsonism. 06
(b) Write etiology and pathogenesis of cancer 05
(c) Write mechanism of different type of inflammation 05
Q.5 (a) Explain the pathogenesis and clinical manifestations of AIDS. 06
(b) Describe basic principles of wound healing in the skin. 05
(c) Write about various types of arrhythmia 05
Q. 6 (a) Classify anemia. Write detailed note on Iron deficiency anemia. 06
(b) Define hepatitis. What are signs and symptoms of hepatitis? Write causes of 05
hepatitis.
(c) Describe in details the signs and symptoms of schizophrenia. 05
Q.7 (a) Discuss signs and symptoms and complications of urinary tract infections. 06
(b) Write etiology, clinical manifestation and treatment of Depression. 05
(c) Explain pathophysiology of Atherosclerosis 05

***************
Seat No.: ________ Enrolment No.______________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM – SEMESTER – 3- EXAMINATION –WINTER - 2018

Subject Code: BP304TT Date: 10/12/2018

Subject Name: Pathophysiology
Time: 10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 Choose correct option for following questions 16

1 Find out the correct statement with regards to tuberculosis:
(a) Mycobacterium tuberculosis is a facultative aerobic organism
(b) Primary infection of tuberculosis is in GI tract
(c) It represents granulomatous inflammation
(d) Type of cell death in tuberculosis is apoptosis
2 Find out pair of major phagocytes of blood:
(a) Monocyte, Neutrophils (c) Lymphocyte, Neutrophils
(b) Basophil, Eiosinophil (d) Lymphocyte, Monocyte
3 Which of the following gland undergoes physiological atrophy with increase in
age?
(a) Thymus (c) Adrenal gland
(b) Spleen (d) Pituitary gland
4 Expression of pro-apoptotic molecules is a novel target for treatment of:
(a) Diabetes (c) Alzheimer’s disease
(b) AIDS (d) Cancer
5 Find out arachidonic acid metabolite which induces platelet aggregation
(a) Thromboxane A2 (c) Histamine
(b) Prostaglandin I2 (d) Serotonin
6 Formation of uric acid crystals in synovial joints resulting in inflammation of
synovial joints is known as:
(a) Osteoarthritis (c) Rheumatism
(b) Gouty arthritis (d) Spondylitis
7 Peptic ulcer is due to infection of:
(a) Helicobacter pylori infection in ileum
(b) Helicobacter pylori infection in pylorus
(c) Entamoebica histolytica infection in ileum
(d) Entamoebica histolytica infection in pylorus
8 Carcinoma refers to cancer of:
(a) Epithelial tissue (c) Nervous tissue
(b) Connective tissue (d) Muscular tissue
9 Widal test is used for diagnosis for:
(a) Syphilis (c) Gonorrhoea
(b) Typhoid (d) AIDS
10 Commonly observed bone disorder in menopause is:
(a) Rickets (c) Osteomalacia
Page 1 of 3
 (b) Osteomyelitis (d) Osteoporosis
11 Hemophilia-A occurs due to deficiency of:
(a) Clotting factor XII (c) Clotting factor VII
(b) Clotting factor VIII (d) Clotting factor V
12 Pulmonary edema is commonly observed complication in:
(a) Essential hypertension (c) Congestive cardiac failure
(b) Secondary hypertension (d) Megaloblastic anaemia
13 Hyperkalaemia can be observed due to:
(a) Hyperaldosteronism (c) Cushing’s syndrome
(b) Excess insulin therapy (d) Addison’s disease
14 Epilepsy may result in convulsions when neuronal firing increases in
(a) Medulla oblongata (c) Midbrain
(b) Motor cortex (d) Cerebellum
15 Diabetes insipidus refers to:
(a) Sodium and water retention
(b) Increased urine formation due to deficiency of aldosterone
(c) Increased urine formation due to increase in urine sugar
(d) Increased urine formation due to deficiency of anti-diuretic hormone
16 Find out the correct statement with regards to urinary tract infection:
(a) Upper urinary tract infections are more common as compare to lower
urinary tract infections.
(b) Urinary tract infections are more common in female as compared to male.
(c) Major causative organisms of urinary tract infection are gram positive in
nature.
(d) Diuresis is a commonly observed symptom of urinary tract infection.
Q.2 (a) Enlist hereditary anaemia. Add a note on sickle cell anaemia. 06
(b) Compare and contrast: Type 1 and Type 2 diabetes mellitus. Write 05
complications of diabetes in brief.
(c) Describe pathogenesis of congestive cardiac failure. 05
Q.3 (a) Explain following terms: (i) Homeostasis (ii) Negative feedback system 06
(iii) Metaplasia
(b) Describe pathogenesis of cancer in brief. 05
(c) What is angina pectoris? Classify it. Discuss pathogenesis of angina pectoris in 05
brief.
Q.4 (a) Give comment on: 06
(i) Hypertension is a silent killer.
(ii) Vitamin B12 deficiency is referred as megaloblastic anaemia.
(iii) Schizophrenia is a neurodevelopmental disorder.
(b) Define inflammation. Describe cellular events of acute inflammation in detail. 05
(c) Describe pathogenesis, symptoms and complications for acute renal failure. 05
Q.5 (a) Draw life cycle of HIV virus. Discuss diagnosis, symptoms and pathogenesis of 06
AIDS.
(b) Enlist various types of hepatitis. Discuss etiology, symptoms and complications 05
of hepatitis A.
(c) Describe etiology and pathogenesis of rheumatoid arthritis. 05
Q. 6 (a) Write symptoms for following disease: 06
(i) Cretinism (ii) Depression (iii) Inflammatory bowel disease

Page 2 of 3
 (b) Explain the processes involved in healing of skin wounds in brief. 05
(c) Discuss symptoms and pathogenesis of COPD. 05
Q.7 (a) Enlist various factors leading to cell injury. Discuss reversible cell injury due to 06
ischaemia.
(b) Define apoptosis. Write in detail about mechanism of apoptosis. 05
(c) Enlist neurodegenerative diseases. Write neurochemistry and symptoms of 05
Parkinson’s disease.
***************

Page 3 of 3
Seat No.: ________ Enrolment No.______________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM – SEMESTER – 3- EXAMINATION –WINTER - 2018

Subject Code: BP304TT Date: 10/12/2018

Subject Name: Pathophysiology
Time: 10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 Choose correct option for following questions 16

1 Find out the correct statement with regards to tuberculosis:
(a) Mycobacterium tuberculosis is a facultative aerobic organism
(b) Primary infection of tuberculosis is in GI tract
(c) It represents granulomatous inflammation
(d) Type of cell death in tuberculosis is apoptosis
2 Find out pair of major phagocytes of blood:
(a) Monocyte, Neutrophils (c) Lymphocyte, Neutrophils
(b) Basophil, Eiosinophil (d) Lymphocyte, Monocyte
3 Which of the following gland undergoes physiological atrophy with increase in
age?
(a) Thymus (c) Adrenal gland
(b) Spleen (d) Pituitary gland
4 Expression of pro-apoptotic molecules is a novel target for treatment of:
(a) Diabetes (c) Alzheimer’s disease
(b) AIDS (d) Cancer
5 Find out arachidonic acid metabolite which induces platelet aggregation
(a) Thromboxane A2 (c) Histamine
(b) Prostaglandin I2 (d) Serotonin
6 Formation of uric acid crystals in synovial joints resulting in inflammation of
synovial joints is known as:
(a) Osteoarthritis (c) Rheumatism
(b) Gouty arthritis (d) Spondylitis
7 Peptic ulcer is due to infection of:
(a) Helicobacter pylori infection in ileum
(b) Helicobacter pylori infection in pylorus
(c) Entamoebica histolytica infection in ileum
(d) Entamoebica histolytica infection in pylorus
8 Carcinoma refers to cancer of:
(a) Epithelial tissue (c) Nervous tissue
(b) Connective tissue (d) Muscular tissue
9 Widal test is used for diagnosis for:
(a) Syphilis (c) Gonorrhoea
(b) Typhoid (d) AIDS
10 Commonly observed bone disorder in menopause is:
(a) Rickets (c) Osteomalacia
Page 1 of 3
 (b) Osteomyelitis (d) Osteoporosis
11 Hemophilia-A occurs due to deficiency of:
(a) Clotting factor XII (c) Clotting factor VII
(b) Clotting factor VIII (d) Clotting factor V
12 Pulmonary edema is commonly observed complication in:
(a) Essential hypertension (c) Congestive cardiac failure
(b) Secondary hypertension (d) Megaloblastic anaemia
13 Hyperkalaemia can be observed due to:
(a) Hyperaldosteronism (c) Cushing’s syndrome
(b) Excess insulin therapy (d) Addison’s disease
14 Epilepsy may result in convulsions when neuronal firing increases in
(a) Medulla oblongata (c) Midbrain
(b) Motor cortex (d) Cerebellum
15 Diabetes insipidus refers to:
(a) Sodium and water retention
(b) Increased urine formation due to deficiency of aldosterone
(c) Increased urine formation due to increase in urine sugar
(d) Increased urine formation due to deficiency of anti-diuretic hormone
16 Find out the correct statement with regards to urinary tract infection:
(a) Upper urinary tract infections are more common as compare to lower
urinary tract infections.
(b) Urinary tract infections are more common in female as compared to male.
(c) Major causative organisms of urinary tract infection are gram positive in
nature.
(d) Diuresis is a commonly observed symptom of urinary tract infection.
Q.2 (a) Enlist hereditary anaemia. Add a note on sickle cell anaemia. 06
(b) Compare and contrast: Type 1 and Type 2 diabetes mellitus. Write 05
complications of diabetes in brief.
(c) Describe pathogenesis of congestive cardiac failure. 05
Q.3 (a) Explain following terms: (i) Homeostasis (ii) Negative feedback system 06
(iii) Metaplasia
(b) Describe pathogenesis of cancer in brief. 05
(c) What is angina pectoris? Classify it. Discuss pathogenesis of angina pectoris in 05
brief.
Q.4 (a) Give comment on: 06
(i) Hypertension is a silent killer.
(ii) Vitamin B12 deficiency is referred as megaloblastic anaemia.
(iii) Schizophrenia is a neurodevelopmental disorder.
(b) Define inflammation. Describe cellular events of acute inflammation in detail. 05
(c) Describe pathogenesis, symptoms and complications for acute renal failure. 05
Q.5 (a) Draw life cycle of HIV virus. Discuss diagnosis, symptoms and pathogenesis of 06
AIDS.
(b) Enlist various types of hepatitis. Discuss etiology, symptoms and complications 05
of hepatitis A.
(c) Describe etiology and pathogenesis of rheumatoid arthritis. 05
Q. 6 (a) Write symptoms for following disease: 06
(i) Cretinism (ii) Depression (iii) Inflammatory bowel disease

Page 2 of 3
 (b) Explain the processes involved in healing of skin wounds in brief. 05
(c) Discuss symptoms and pathogenesis of COPD. 05
Q.7 (a) Enlist various factors leading to cell injury. Discuss reversible cell injury due to 06
ischaemia.
(b) Define apoptosis. Write in detail about mechanism of apoptosis. 05
(c) Enlist neurodegenerative diseases. Write neurochemistry and symptoms of 05
Parkinson’s disease.
***************

Page 3 of 3
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM – SEMESTER –3 EXAMINATION – SUMMER-2024

Subject Code: BP304TT Date: 15/06/2024

Subject Name: Pathophysiology
Time: 02.30 p.m. to 5.30 p.m. Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define inflammation. Explain vascular and cellular events of acute 06
inflammation.
(b) Enlist the chemical mediators of inflammation. Explain the role of arachidonic 05
acid metabolites in inflammation.
(c) Define: Atrophy, Homeostasis, Hyperplasia, Metaplasia and Dysplasia. 05
Q.2 (a) Discuss the pathophysiology of Atherosclerosis. 06
(b) Define Ischemic heart disease? Discuss different types of angina pectoris. 05
(c) Write etiological factors and pathophysiology of hypertension. 05
Q.3 (a) Explain the pathogenesis of asthma. Write differences between Bronchial 06
asthma and COPD.
(b) Explain pathogenesis of Acute renal failure. 05
(c) Discuss clinical features and pathogenesis of asthma. 05
Q.4 (a) What is anemia? Enlist various types of Anemia and write a note on iron 06
deficiency anemia.
(b) Discuss in detail about wound healing process. 05
(c) Explain etiology and pathogenesis of Parkinson’s disease. 05
Q.5 (a) Describe signs, symptoms and complications of urinary tract infections. 06
(b) Write a brief note on disorder of sex hormone. 05
(c) Describe the signs and symptoms of various forms of epilepsy. 05
Q. 6 (a) Write etiology and pathogenesis of cancer. 06
(b) Explain pathophysiology of Peptic ulcer disease. 05
(c) Discuss diagnosis and pharmacotherapeutic approach for Rheumatoid arthritis. 05
Q.7 (a) Write the pathogenesis of AIDS. 06
(b) Explain various etiological factors and clinical management of Tuberculosis. 05
(c) Explain the drugs used for the treatment of Gonorrhoea. 05

***************
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM- SEMESTER–3 - EXAMINATION – SUMMER -2023

Subject Code:BP304TT Date: 11/08/2023

Subject Name: Phathophysiology
Time: 10:30AM TO 01:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph. - SEMESTER– III • EXAMINATION – SUMMER -2022

Subject Code:BP304TT Date:08/09/2022

Subject Name: PATHOPHYSIOLOGY
Time: 02:30pm to 05:30pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Explain the cellular and molecular mechanism of reversible and irreversible 06
cell injury due to hypoxia/ischaemia.
(b) Discuss in detail about wound healing process. 05
(c) Define and classify cellular adaptations. Write the causes of atrophy and 05
Hyperplasia.
Q.2 (a) Explain the following terms: 06
1) Angina
2) Atherosclerosis
3) Parkinson’s disease
(b) Enlist cellular events in acute inflammation. Explain chemotaxis. 05
(c) Write the pathological difference between Asthma and COPD. 05
Q.3 (a) Explain the complications of Diabetes. 06
(b) Explain etiology and sign and symptoms of CCF. 05
(c) Explain pathogenesis of Acute renal failure. 05
Q.4 (a) Classify Anemia. Explain Causes, Pathogenesis,and symptoms of any one 06
anemia.
(b) Write a note on Gout. 05
(c) Explain in brief about Hepatitis. 05
Q.5 (a) Write the pathogenesis of AIDS. 06
(b) Explain pathogenesis and symptoms of tuberculosis. 05
(c) Define Rheumatoid arthritis. Explain causes and symptoms of it. 05
Q. 6 (a) What is Stroke? Explain causes of stroke. 06
(b) Write complication of Chronic renal failure. 05
(c) Write pathological changes in thyroid disorders. 05
Q.7 (a) Classify Cancer. Write etiology of cancer. 06
(b) Explain causes, pathogenesis, sign and symptoms of Typhoid. 05
(c) Explain pathological changes in Peptic ulcer. 05

***************
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Pharm. - SEMESTER – III • EXAMINATION – SUMMER - 2021

Subject Code: BP304TT Date: 01/09/2021

Subject Name: Pathophysiology
Time: 02:30PM to 05:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Discuss the pathophysiology and pharmacological management of 06

Parkinsonism.
(b) Explain the mechanism of increased vascular permeability in acute 05
inflammation.
(c) Enlist chemical mediators involved in inflammation. Explain the role of 05
histamine in inflammation.
Q.2 (a) Describe clinical presentation, diagnosis and pharmacotherapy of Angina 06
pectoris.
(b) Write in detail about mechanism of cell injury. 05
(c) Define: Hypertrophy, Atrophy, Hyperplasia, Necrosis, and Homeostasis. 05
Q.3 (a) Explain in details about the pathophysiology of Atherosclerosis. 06
(b) Explain the pathogenesis behind peptic ulcer disease. How gastric ulcer can be 05
differentiated from duodenal ulcer?
(c) Discuss the therapeutic options in management of Alzheimer’s disease. 05
Q.4 (a) Write a note on pathophysiology and management of congestive heart failure. 06
(b) Describe the signs and symptoms and management of acute renal failure 05
(c) Write the diagnosis and pharmacotherapeutic approach for Rheumatoid 05
arthritis.
Q.5 (a) Describe the pathology of AIDS and its clinical manifestations in detail. 06
(b) Explain the pathogenesis of asthma. Write differences between Bronchial 05
asthma and COPD
(c) Describe the treatment of grand mal epilepsy in detail. 05
Q. 6 (a) Write pathophysiology, risk factors, diagnosis, complications, and treatment 06
management options of Hepatitis B.
(b) Explain various etiological factors and clinical management of Tuberculosis. 05
(c) Explain the drugs used for the treatment of Gonorrhoea. 05
Q.7 (a) Classify types of hypertension. Write a note on risk factors and management of 06
Hypertension.
(b) Write a note on risk factors and long term complications of diabetes mellitus. 05
(c) Enlist various types of Anemia and write a note on iron deficiency anemia. 05

***************
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Pharm - SEMESTER– III • EXAMINATION – SUMMER -2020

Subject Code: BP304TT Date: 04-11-2020

Subject Name: Pathophysiology
Time: 2:30 PM TO 5:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Differentiate Asthma and COPD. Enlist various risk factors for asthma. 06
(b) Discuss etiology and pathophysiology of congestive heart failure. 05
(c) Explain pathogenesis and clinical manifestations of peptic ulcer disease. 05
Q.2 (a) Explain various mechanisms of pathogenesis of cell injury. 06
(b) Describe cellular adaptive changes against injury. 05
(c) Write a note on Apoptosis. 05
Q.3 (a) Describe pathophysiology and sign-symptoms of UTI. 06
(b) Explain causes and pathogenesis of atherosclerosis. 05
(c) Discuss pathophysiology of Alzheimer’s disease. 05
Q.4 (a) Discuss different types of vascular events of acute inflammation. 06
(b) Write a note on Phagocytosis. 05
(c) Enlist various chemical mediators of inflammation. Describe plasma derived 05
mediators in detail.
Q.5 (a) 1. Describe various types of hepatitis. 06
2. Differentiate Ulcerative colitis and Crohn’s disease.
(b) Explain pathophysiology and clinical manifestations of Parkinson’s disease. 05
(c) Discuss pathophysiology of AIDS. 05
Q. 6 (a) Describe in detail various types of anemia. 06
(b) Compare and contrast Rheumatoid arthritis and Gout. 05
(c) Describe pathophysiology and sign-symptoms of acute renal failure. 05
Q.7 (a) Explain cause and pathogenesis of Tuberculosis. Discuss DOT therapy in brief. 06
(b) Describe etiology and pathophysiology of hypothyroidism. 05
(c) Classify cancer. Discuss pathogenesis of cancer. 05

***************
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER– 3 EXAMINATION – SUMMER -2019

Subject Code: BP304TT Date: 04-06-2019

Subject Name: Pathophysiology
Time: 02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define alzheimer disease. Write about pathophysiology and symptoms of 06
alzheimer and its treatment.
(b) Write a short note on 05
i. Asthma
ii. Ulcerative colitis
(c) Write in detail about electrolyte imbalance. Explain the role of electrolytes in 05
the electrophysiology of heart.
Q.2 (a) Define atherosclerosis. Write in detail about pathophysiology of atherosclerosis 06
causes and medications used.
(b) What is schizophrenia. Explain the process of occurrence of schizophrenia 05
symptoms.
(c) Write about clinical signs of Inflammation. Explain mechanism of 05
inflammation and mediator’s of inflammation.

Q.3 (a) Enumerate types of sickle cell anemia. Write about pathophysiology of sickle 06
cell anemia and its treatment.
(b) Define Homeostasis. Explain about Feedback systems. 05
(c) Write a short note on 05
i. Chronic renal failure
ii. Gout
Q.4 (a) Explain in brief about thyroid disorders. Write about etiology and 06
pathophysiology of goiter.
(b) Explain types of peptic ulcer. Write about pathogenesis and treatment of peptic 05
ulcer.
(c) Write a short note on malignant tumor. 05
Q.5 (a) Define gonorrhea. Write about pathophysiology of gonorrhea, diagnosis and its 06
treatment.
(b) Write about pathogenesis of B.P. Explain in detail about role of kidney in 05
hypertension.
(c) Write a short note on meningitis. 05
Q. 6 (a) Define UTI. Write in detail about etiology, pathophysiology and its treatment. 06
(b) Write a short note on PCOS. 05
(c) Write about cell injury. Explain in detail about cellular adaptive changes. 05
Q.7 (a) Classify diabetic mellitus. Discuss the causes, symptoms and treatment of 06
diabetic mellitus.
(b) Write in detail about types of Hepatitis and its causes. 05
(c) Define AIDS. Write about pathogenesis, diagnosis and its prevention. 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER– 3 EXAMINATION – SUMMER -2019

Subject Code: BP304TT Date: 04-06-2019

Subject Name: Pathophysiology
Time: 02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define alzheimer disease. Write about pathophysiology and symptoms of 06
alzheimer and its treatment.
(b) Write a short note on 05
i. Asthma
ii. Ulcerative colitis
(c) Write in detail about electrolyte imbalance. Explain the role of electrolytes in 05
the electrophysiology of heart.
Q.2 (a) Define atherosclerosis. Write in detail about pathophysiology of atherosclerosis 06
causes and medications used.
(b) What is schizophrenia. Explain the process of occurrence of schizophrenia 05
symptoms.
(c) Write about clinical signs of Inflammation. Explain mechanism of 05
inflammation and mediator’s of inflammation.

Q.3 (a) Enumerate types of sickle cell anemia. Write about pathophysiology of sickle 06
cell anemia and its treatment.
(b) Define Homeostasis. Explain about Feedback systems. 05
(c) Write a short note on 05
i. Chronic renal failure
ii. Gout
Q.4 (a) Explain in brief about thyroid disorders. Write about etiology and 06
pathophysiology of goiter.
(b) Explain types of peptic ulcer. Write about pathogenesis and treatment of peptic 05
ulcer.
(c) Write a short note on malignant tumor. 05
Q.5 (a) Define gonorrhea. Write about pathophysiology of gonorrhea, diagnosis and its 06
treatment.
(b) Write about pathogenesis of B.P. Explain in detail about role of kidney in 05
hypertension.
(c) Write a short note on meningitis. 05
Q. 6 (a) Define UTI. Write in detail about etiology, pathophysiology and its treatment. 06
(b) Write a short note on PCOS. 05
(c) Write about cell injury. Explain in detail about cellular adaptive changes. 05
Q.7 (a) Classify diabetic mellitus. Discuss the causes, symptoms and treatment of 06
diabetic mellitus.
(b) Write in detail about types of Hepatitis and its causes. 05
(c) Define AIDS. Write about pathogenesis, diagnosis and its prevention. 05

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