NARCOTIC DRUGS
• Dangerous Drugs
• Laws Governing Dangerous Drugs
• Classification of different dangerous drugs
INTRODUCTION
A drug can be defined as a natural or synthetic
substance that is used to produce physiological or
psychological effects in humans or other higher order
animals.
Narcotic drugs are analgesics, meaning they relieve
pain by a depressing action on the central nervous
system. It is a drug capable of causing narcosis or
depressing effect on the body. It induces sleep or
insensibility by action on the nerve center.
INTRODUCTION
The regular use of a narcotic drug will invariably lead
to physical dependence.
The most common source for these narcotic drugs is
opium, extracted from poppies.
DANGEROUS DRUGS
PROHIBITED DRUGS REGULARTED DRUGS
Opium Self inducing sedatives
Heroine Secobabital
Morphine Phenobarbital
Coca leaf and its derivatives Hypnotic drugs
LSD Etc.
Indian hemp
Etc.
LAWS GOVERNING
DANGEROUS DRUGS
1972 the Dangerous Drug Act, RA 6425 was
enacted and approved.
The laws on Dangerous Drugs are found in Article II
and Article III of the R.A. 6425 known as the
Dangerous Drug Act of 1972 as amended.
Article II
PROHIBITED DRUGS
SEC.3 importation of Prohibited Drugs
SEC.4. Sale, Administration, Delivery, Distribution and transportation of
Prohibited Drugs
SEC.5. Maintenance of a den, Dive or Resort for Prohibited Drugs
SEC.6. Employers and Visitors of Prohibited Drug Den
SEC.7. Manufacture of Prohibited Drug
SEC.8. Possession or Use of Prohibited Drug
SEC.9. Cultivation of Plants which are source of Prohibited Drugs
SEC.10. Records, Prescription, sales and Purchase of Prohibited Drugs
SEC.11 Unlawful Prescription of Prohibited Drugs
SEC.12. Unnecessary prescription of Prohibited Drugs
SEC.13 Possession of Opium pipe and other Praraphernalis of Prohibited
Drugs
Article III
REGULATED DRUGS
SEC.14. Importation of Regulated Drugs
SEC.15. Sales, Administration, Dispensation, delivery
transportation and distribution of Regulated Drugs
SEC.16. Possession or Use of Regulated Drugs
SEC.17. Record of Prescription, Sales , Purchases
Acqusition of Regulated Drugs
SEC.18. Unlawful prescription of Regulated Drugs
SEC.19. Unnecessary Prescription of Regulated Drugs
OPIUM
The dried latex obtain from seedpod of Opium poppy
Papaver somniferum Linne
The Poppy plant is an annual herb and must be
cultivated.
Street names : Buddha, Chinese molasses, Chinese
Tobacco
Earliest record was as early as 3 B.C
Indeginous to Asia Minor, and widely grown in
China, India, Turkey, Macedonia, Yugoslavia, Bulgaria
and Iran.
MORPHINE
Crystalline substance known as “salt of opium”
Morphine is readily extracted from opium and is used
to synthesize heroin.
– Therapeutic use of morphine are:
1. To relieve pain.
2. Useful in checking diarrhea
3. Valuable in treatment of dry, non-productive coughs
4. Excellent for pre- operative medication.
5. Reduce blood pressure and bleeding.
6. Useful hypnotic when pain interferes with ability to sleep
Morphine and Opium Addicts
Opium Addicts – are usually quieter , more apt to be
lethargic, slow and dreamy and are rarely as
impulsive and quick in their behaviour.
Morphine addicts – the individual is lethargic, the
skin is sallow and pallorous. They complain often of
being cold, and there is frequently a subnormal
temperature. Addicts show bodily neglect and are
careless in their dress
HEROIN
Prepared by heating morphine with acetic anhydride
or acetyl chloride.
Five times as potent as morphine but produces a
most vicious addiction.
Heroin produces a “high” that is accompanied by
drowsiness and a sense of well-being that generally
last for three to four hours.
Addicts frequently dissolve heroin in water by
heating it in a spoon, and then inject in the skin.
What does it look like?
COCAINE AND CRACK COCAINE
COCAINE CRACK COCAINE
What do they look like: What do they look like:
– Crystalline powder – White, off-white crystalline rocks
How taken: How taken:
– Orally, snorted, inhaled or injected – Inhaled from pipe, but sometimes
injected
EFFECTS: increase heart rate, breathing, blood pressure, thoughts and activity levels. It also
lifts mood and gives a sense of energy and well being.
OPIATES
Codeine is also present in opium, but it is usually
prepared synthetically from morphine.
OPIATES
OxyContin is prescribed to a million patients for
treatment of chronic pain.
Methadone is another well-known synthetic opiate.
Methadone, which is pharmacologically related to
heroin, appears to eliminate the addict’s desire for
heroin while producing minimal side effects.
What does it look like?
HALLUCINOGENS
Another class of drugs is hallucinogens; marijuana is
the most well-known member of this class.
Hallucinogens cause marked changes in normal
thought processes, perceptions, and moods.
Marijuana is the most controversial drug in this class
because its long-term effects on health are still
largely unknown.
MARIJUANA
Marijuana refers to a preparation derived from the
plant Cannabis.
The chemical substance largely responsible for the
hallucinogenic properties of marijuana is known as
tetrahydrocannabinol, or THC.
The THC content of Cannabis varies in different
parts of the plant, generally decreasing in the
following sequence: resin, flowers, leaves, with little
THC in the stem, roots or seeds.
Marijuana is either smoked or taken orally but the
most prevalent method used is smoking.
MARIJUANA
The THC-rich resin is known as hashish.
Marijuana does not cause physical dependency, but
the risk of harm is in heavy, long-term use.
MARIJUANA
HALLUCINOGENS
Other hallucinogens include LSD, mescaline, PCP,
psilocybin, and MDMA (Ecstasy).
LSD is synthesized from lysergic acid, and can
cause hallucinations that can last for 12 hours.
Phencyclidine, or PCP, is often synthesized in
clandestine laboratories and is often smoked,
ingested, sniffed.
What does it look like?
CLUB DRUGS
The term club drugs refers to synthetic drugs that are used
at nightclubs, bars, and raves (all-night dance parties).
Substances that are often used as club drugs include, but
are not limited to, MDMA (Ecstasy), GHB (gamma
hydroxybutyrate), Rohypnol (“Roofies”), ketamine, and
methamphetamine.
GHB and Rohypnol are central nervous system depressants
that are often connected with drug-facilitated sexual assault,
rape, and robbery.
CLUB DRUGS
Methylenedioxymethamphetamine, also known as
MDMA or Ecstasy, is a synthetic mind-altering drug
that exhibits many hallucinogenic and amphetamine-
like effects.
Ecstasy enhances self-awareness and decreases
inhibitions, however, seizures, muscle breakdown,
stroke, kidney failure, and cardiovascular system
failure often accompany chronic abuse.
CLUB DRUGS
Ketamine is primarily used as a veterinary animal
anesthetic that in humans causes euphoria and
hallucinations.
Ketamine can also cause impaired motor functions,
high blood pressure, amnesia, and mild respiratory
depression.
ANABOLIC STEROIDS
Yet another category of drugs is the anabolic
steroids.
These are synthetic compounds that are chemically
related to the male sex hormone testosterone.
Anabolic steroids are often abused by individuals
who are interested in accelerating muscle growth.
ANABOLIC STEROIDS
Side effects include unpredictable effects on mood
and personality, depression, diminished sex drive,
halting bone growth, and liver cancer.
DEPRESSANTS
These include alcohol (ethanol), barbiturates,
tranquilizers, and various substances that can be
sniffed, such as airplane glue, model cement, or
aerosol gas propellants such as freon.
Alcohol (ethyl alcohol) enters the body’s bloodstream
and quickly travels to the brain, where it acts to
suppress the brain’s control of thought processes
and muscle coordination.
DEPRESSANTS
Barbiturates, or “downers,” are normally taken orally
and create a feeling of well-being, relax the body,
and produce sleep.
Tranquilizers, unlike barbiturates, produce a relaxing
tranquility without impairment of high-thinking
faculties or inducing sleep.
Sniffing has immediate effects such as exhilaration,
but impairs judgment and may cause liver, heart,
and brain damage, or even death.
What does it look like?
STIMULANTS
The drug classification of stimulants includes
amphetamines, sometimes known as “uppers” or
“speed,” and cocaine, which in its free-base form is
known as crack.
Stimulants are substances taken to increase alertness
or activity, followed by a decrease in fatigue and a loss
of appetite.
Amphetamine and methamphetamine, often injected
intravenously, cause an initial “rush,” followed by an
intense feeling of pleasure.
This is followed by a period of exhaustion and a
prolonged period of depression.
METHAMPHETAMINE
Crystal meth, sometimes simply known as ‘meth,’ is a drug
that can addict a person from the first time they try it.
Methamphetamine is completely artificial, created of very
toxic chemicals.
These chemicals can initially offer a high, but they can also
cause serious harm or even death not only for those who
take the drugs, but for those who make them as well.
Methamphetamine ingredients can be combined in a wide
variety of formulas, but the basics are the same – and most
of them are highly flammable and extremely lethal if
ingested in any way. The resulting product is just as bad, if
not worse..
What you need?
METHAMPHETAMINE
A number of the ingredients commonly used in creating meth are
extremely toxic:
Materials
How to Cook?
The equipment for making meth typically uses
common items found in everyone’s home. This might
include glass bottles, cheesecloth, aluminum foil,
oven-safe or heat-safe dishes, rubber tubing, and
other common items.
Everything can be picked up at a hardware store or
discount store. In addition, most of the chemicals
used in meth are perfectly legal and can even be
acquired in large quantities. That explains the
growing popularity of making meth in the everyday
kitchen.
How to cook?
It starts with grinding down the cold medication pills
and adding a binder to them to separate the
pseudoephedrine from the medication.
Then the medication is mixed with acid and red
phosphorus, bubbled for a while, and then the red
phosphorous is filtered out.
Next, caustic soda is added to give the meth a
“base,” a process that has to be carefully cooled to
avoid explosion.
After that, Freon or other chemicals are added to
separate the liquid from the solids.
How to cook?
Hydrogen chloride then turns the meth into a salt,
which lowers the acidity. It is then dried on a cloth.
The final product is filled with yet more additives to
make it even more addictive, then it is packaged for
sale and use.
METHAMPHETAMINE
Side effects of Meth
Long term use Observable physical
– Weight loss effects
– Severe dental problems: Meth Mouth
– Permanent damage to blood vessels – sunken eyes
of heart and brain – dark baggy eye lids
– High blood pressure leading to heart
attacks, strokes and death – facial drooping,
– Liver and kidney damage particularly the mouth and
– Destruction of tissues in nose if lower lips
snorted
– Respiratory problems and lung – pale skin
damage if smoked – dark blue-black lips
– Infectious diseases and abscesses if
injected – wrinkles from skin losing
– Damage to the brain similar to elasticity
Alzheimer’s disease
– Convulsions
– acne and sores \
Collection and Preservation
The field investigator has the responsibility of ensuring that
the evidence is properly packaged and labeled for the
laboratory.
Generally common sense is the best guide, keeping in mind
that the package must prevent the loss of the contents
and/or cross-contamination.
Often the original container in which the drug was
seized will suffice.
All packages must be marked with information that is
sufficient to ensure identification by the officer in the
future and establish the chain of custody.
Drug Detection Times
amphetamines: up to 4 days
cocaine: up to 72 hrs.
opiates: up to 5 days
PCP: up to 6 days
barbiturates: up to a week
benzodiazepines: up to a week
… then there’s alcohol & cannabinoids
Cannabinoids
30+ day detection window often exaggerates
duration of detection window
reasonable & pragmatic court guidance
detection time: at 50 ng/mL cutoff
– up to 3 days for single event/occasional use
– up to 10 days for heavy chronic use
detection time: at 20 ng/mL cutoff
– up to 7 days for single event/occasional use
– up to 21 days for heavy chronic use
Preliminary Analysis
Faced with the prospect that the unknown substance may be
any one of a thousand or more commonly encountered drugs,
the analyst must employ screening tests to reduce these
possibilities to a small and manageable number.
This objective is often accomplished by subjecting the material
to a series of color tests that will produce characteristic colors
for the more commonly encountered illicit drugs.
Preliminary Analysis
screening test for marijuana
– Duquenois-Levine Color test
THC screening….. Marijuana and Hashish
Drops added to vegetation, turns purple color
Color screening test
Marquis Test – ex: Nark II
Primary presumptive test used for ecstasy testing. Also used to test
for cocaine, opiates (e.g. methadone, heroin), and methamphetamine.
– Purple Opiates
– Orange to brown Amphetamine & Meth
– Blue Ecstasy
– Red Aspirin
– Pink cocaine
COLOR TEST
Preliminary Analysis
Microcrystalline tests can also be used to identify specific
drug substances by studying the size and shape of crystals
formed when the drug is mixed with specific reagents.
•
• left cocaine,
• right marijuana
Confirmational Determination
Once this preliminary analysis is completed, a
confirmational determination is pursued.
Forensic chemists will employ a specific test to identify a
drug substance to the exclusion of all other known chemical
substances.
Typically infrared spectrophotometry or gas
chromatography-mass spectrometry is used to specifically
identify a drug substance.
Special Test
Morphine
Iodic acid test- 5% potassium iodate and dilute
sulphuric acid turns violet
Prussian blue test- few drops of 3% ferricyanide +
10% ferric chloride = Prussian blue color
Nitrous acid test – a yellow green color develops
turns red upon addition of NaOH.
Special Test
Codine
Pellagri’s Test – 3-4ml HCl + 3-4 drops of conc.
Sulphuric acid + evaporate = emerald green color
Furfural Test- sulphuric acid then heat + cane-sugar
solution (slowly) = purple-red color
Prussian Blue Test – green color
Ferric Chloride Test – conc. Sulphuric acid + 1 drop
of 10% ferreic chloride solution = blue
Oxidation Test- blue color
Special Test
Cocaine
Potassium permanganate test – saturated potassium
permanganate solution = violet crystalline precipitate
Chromic acid test – 5%chromic acid + HCl =
crystalline orange precipitate
Iodic acid test – sulphuric acid + small particle of
potassium iodate + evaporate sample = brown to
olive green to blue to violet then disappear
Common Drugs of Abuse
A comprehensive guide to the most commonly abused drugs
Table of Contents
Amphetamines
Cocaine
Marijuana
Opiates
Phencyclidine
MDMA
Barbiturates
Benzodiazepines
Methadone
Methqualone
Propoxyphene
GHB
Rohypnol
Ketamine
LSD
Anabolic Steroids
Amphetamines
Street Names
Uppers
Speed
Black Beauties
Meth
Whites
Jelly Beans
Dexies
Crank
White Cross
Benny
Crystal
More than 70% of substance abusers hold jobs.
-American Council for Drug Education
What to Look For
Tablets of varying colors, possible chain smoking.
Physical Symptoms
Long periods without rest or sleep, loss of appetite, anxiety, irritability, rapid
speech, tremors, mood elevation.
Substances / Time Detectable
Methamphetamine
Urine: 1 to 3 days
Hair: up to 90 days (depending on hair length)
Oral Fluid: 24 to 36 hours
Amphetamine
Urine: 1 to 3 days
Hair: up to 90 days (depending on hair length)
Oral Fluid: 24 to 36 hours
Dangers
Disorientation, severe depression, paranoia, possible hallucinations, increase
in blood pressure, fatigue.
Cocaine
Street Names
Coke
Nose Candy
Crack
Snow
White Candy
C
Flake
Freebase
Toot
Blow
Rock
What to Look For
Glassine envelopes, razors, small spoons, bitter white crystaline
powder, granular rocks.
Physical Symptoms
Short-lived euphoria changing to depression, irritability,
nervousness, tightness of muscles.
Substances / Time Detectable
Benzoylegonine
Urine: 1 to 3 days
Hair: up to 90 days (depending on hair length)
Oral Fluid: 24 to 36 hours
Dangers
Shallow breathing, fever, anxiety, tremors, possible death from
convulsions or respiratory arrest.
Marijuana
Street Names
Dope
Pot
Reefer
Joint
Smoke
Americans consume 60% of the world’s production of illegal
Weed
drugs. In fact, 23 million individuals use marijuana at least 4 times
a week and 6 million regularly use cocaine..
-American Council for Drug Education
What to Look For
Plastic baggies, rolling paper, “roach” clips, odor of burnt rope.
Physical Symptoms
Alterated perception, dialated pupils, lack of concentration and
coordination, craving for sweets, increased appetite, laughter.
Substances / Time Detectable
11-Nor-delta-9-tetrahydrocannabinol-9-carboxylic acid
Urine: occasional use, 1 to 3 days
Urine: habitual / chronic use, up to 90 days
Hair: up to 90 days (depending on hair length)
Delta-9-tetrahydrocannabinol
Oral Fluid: less than 24 hours
Dangers
Psychological dependence, increased heart rate, impaired short-term
memory, anxiety, lung damage, possible pyschosis with chronic use.
Opiates
Street Names
Heroin (Smack,
Horse, Junk, China
White)
Morphine (M, Miss
Emma)
Codeine (School boy)
Hydrocodone
(Vicodin ®)
Hydromorphone
(Dilaudid®)
Oxycodone
(Percocet®,
Percodan®,
Oxycontin®)
Oxymorphone
(Mumorphan®)
What to Look For
Glassine envelopes, needles and syringes, caps or spoons, tourniquets,
needle marks on arms
Physical Symptoms
Insensitivity to pain, euphoria, sedation, nausea, vomiting, itchiness, watery
eyes, running nose
Substances / Time Detectable
Codeine, Morphine
Urine: 1 to 3 days
Hair: up to 90 days (depending on hair length)
Oral Fluid: 24 to 36 hours
Hydrocodone, Hydromorphone, Oxycodone, Oxymorphone, , 6-Monoacetylmorphine
Urine: 1 to 3 days (< 1 day for 6-monoacetylmorphine)
Oral Fluid: 24 to 36 hours (not applicable for oxycodone or oxymorphone)
Dangers
Lethargy, weight loss, hepatits, slow and shallow breathing, possible death.
Phencyclidine
Street Names
Angel Dust
Devil Stick
PCP
Dummy Dust
Wack
What to Look For
Liquid capsules, white or brown powder on paper stamps, sugar
cubes, cigarettes, joints, injection paraphernalia.
Physical Symptoms
Increased pulse and heart rate, blood pressure and temperature,
possible mood and perception alteration, paranoia, panic, anxiety,
nausea, tremors, suicidal urge.
Substances / Time Detectable
Phencyclidine
Urine: occasional use, 1 to 5 days
Urine: habitul/chronic use, up to 30 days
Hair: up to 90 days (depending on hair length)
Oral Fluid: 24 to 36 hours
Dangers
Unpredictable behavior, flashbacks, possible emotional instability and
psychosis, hallucinations.
MDMA
Street Names
Ecstasy
Adam
XTC
X
Hug Drug
Beans
Love Drug
Lover’s Speed
What to Look For
White odorless crystalline powder, tablets in various colors and
stamped with various patterns
Physical Symptoms
Euphoria, empathetic and unusually warm toward people, touch and
sight sense often heightened
Substances / Time Detectable
3-4 Methylene dioxymethamphetamine (MDMA), 3-4 Methylene
dioxyamphetamine (MDA)
Urine: 1 to 3 days
Hair: up to 90 days (depending on hair length)
Oral Fluid: 24 to 36 hours
Dangers
Tachycardia, hypertension, hyperthermia, mydriasis, diaphoresis,
stimulant, entactogenic effects, visual hallucinations.
Benzodiazepines
Street Names
Downers
Tranqs
What to Look For
Pills and injection paraphernalia
Physical Symptoms
Slurred speech, disorientation, drunken behavior without odor of alcohol
Substances / Time Detectable
Some commonly used brand names are:
Ativan (lorazepam), Dalmane (flurazepam), Diastat orValium (diazepam), Doral
(quazepam), Halcion (triazolam), Klonopin (clonazepam), Librium
(chlordiazepoxide), Paxipam (halazepam), ProSom (estazolam), Restoril
(temazepam), Serax (oxazepam), Tranxene-SD (clorazepate), Xanax
(alprazolam)
Urine: varies from 1 to 14 days (depending on specific benzodiazepine)
Dangers
Shallow respiration, cold and clammy skin, dialated pupils, weak and rapid
pulse, coma, possible death
Methadone
Street Names
Done
Dolophine
Methadose
Dolls
What to Look For
White crystalline powder, tablets, liquid (injectable)
Physical Symptoms
Euphoria, drowsiness, respiratory depression, constricted
pupils, nausea.
Substances / Time Detectable
Methadone and Metabolite
Urine: 1 to 3 days
Dangers
Slow and/or shallow breathing, clammy skin, convulsions,
coma, possible death.
Methaqualone
Street Names
Ludes
Sopor
Lemon
Quaalude
Mequin
The percentage of the U.S. population using illegal drugs increased
from 6.3% in 1999 and 2000 to 7.1% in 2001; this translates to
15.9 million Americans.
-Substance Abuse and Mental Health Services Administration (SAMHSA)
What to Look For
Tablets
Physical Symptoms
Slow heart rate and breathing, lowered blood pressure,
sleepiness, feelings of well-being, loss of coordination, laziness,
impaired perception, confusion, later hangover
Substances / Time Detectable
Methaqualone
Urine: 1 to 7 days
Dangers
Anxiety, insomnia
Propoxyphene
Street Names
None known
In the workplace, substance abusers increase the risk of accidents,
lower productivity, compromise product quality, increase the
workload of others, raise costs and reduce profits.
-American Council for Drug Education
What to Look For
Tablets, capsules
Physical Symptoms
Dizziness, drowsiness, headache, euphoria, sysphoria, asthenia
Substances / Time Detectable
Norpropoxyphene
Urine: 1 to 3 days
Dangers
Skin rash and other allergic reactions occur occasionally and
may be accompanied by drug fever and mucosal lesions, stupor
or coma, convulsions, and respiratory depression.
GHB
Street Names
Liquid Ecstasy
Liquid – X
Everclear
Soap
Easy Lay
Goops
Georgia Home Boy
What to Look For
White, odorless powder, tablet or capsule
Physical Symptoms
Relaxes or sedates the body and slows breathing and heart rate.
Substances / Time Detectable
Gamma hydroxybutyrate
Urine: up to 72 hours
Dangers
Bradycardia, respiratory depression, hallucinations, amnesia.
Rohypnol
Street Names
Roophies
Roofies
Roach
Rope
Circles
MexicanValium
What to Look For
Odorless, tasteless white tablet
Physical Symptoms
Sedative effects, including amnesia, muscle relaxation and the
slowing of psychomotor performance
Substances / Time Detectable
Flunitrazepam metabolite (7-Aminoflunitrazepam)
Urine: 1 to 3 days
Dangers
Respiratory depression, hypotension, disorientation, dizziness,
visual disturbances, anterrograde amnesia.
Ketamine
Street Names
Special K
Lady Kay
Vitamin K
Jet
K
Keets
Super C
CatValium
K - hole
What to Look For
Liquid or white powder
Physical Symptoms
It is a dissocaitive drug that produces effects similar to PCP;
large doses put users into a dreamlike, hallucinogenic state.
Substances / Time Detectable
Ketamine metabolite (Dehydronorketamine)
Urine: 1 to 2 days
Dangers
Tachycardia, hypertension, nystagmus, respiratory depression,
visual hallucinations, cataleptic state.
LSD
Street Names
Acid
L
Blotter
Trips
Cid
Tabs
Microdots
What to Look For
Colorless, odorless tablets or capsules (microdots), liquid
solution on gelatine (window panes), liquid solution diluted and
impregnated on blotting paper (blotter)
Physical Symptoms
Mood – altering effects, flashbacks, severe depression
Substances / Time Detectable
Lysergic acid diethylamide
Urine: 8 hours
Dangers
Tachycardia, hypertension, hyperthermia, mydriasis,
lacrimation, visual hallucinations, synthesias ataxia, tremors.
Anabolic Steroids
Street Names
Testosterone and its
synthetic analogs are listed
as controlled substances
Androstenediols
Androstenediones and
their 19-nor versions
Dehydroepian-
drosterone
Designer anabolic
steroids
What to Look For
Oil-based injectable intramuscular (IM) solutions (ampules, vials, syringes,
bottles), tablets or lozenges for oral administration, sprays, skin lotions.
Physical Symptoms
Yellow tint skin color, acne, gynecomastia (in males), weight gain, fluid
accumulation, psychological disorders such as agressiveness.
In females: marked masculinazation, deeper voice, male pattern hair growth.
Substances / Time Detectable
Multiple metabolites, some parent [Link] to epitesterone rario (T/E) for
detection of endogenous steroid abuse.
Urine: if drug taken orally, up to 3 weeks.
Urine: if drug injected, 3 months to 1 year
Dangers
Liver dysfunction, cardiovascular disease, hypertension, infertility,
virilization (in females)
For further information…
U.S. Department of Health and Human Services and
SAMHSA’s National Clearinghouse for Alcohol &Drug
Information – List of drugs:
[Link]
NIDA (National Institute on Drug Abuse) – Main page:
[Link]
Medical Review Officer Handbook, 8th edition, Theodore F.
Schults, MS, JD, Quadrangle Research LLC, 2002