DRUG NAME

(Generic/Brand Name/ MECHANISM OF INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING

Classification/Dosage/ ACTION RESPONSIBILITIES/PRECAUTION
Frequency)
Binds to an enzyme on GERD/maintenance of Contraindicated in CNS: dizziness, Advise patient to avoid alcohol and
OMEPRAZOLE gastric parietal cells in healing in erosive patients with known drowsiness, fatigue, foods that may cause an increase in GI
40mg the presence of acidic esophagitis. Duodenal hypersensitivity to any headache, weakness. irritation.
OD gastric pH, preventing ulcers (with or without component of the
the final transport of anti-infectives for formulation. CV: chest pain. Instruct patient to report bothersome
hydrogen ions into the Helicobacter pylori). Treatment with GI: abdominal pain, or prolonged side effects, including
gastric lumen. Short-term treatment omeprazole may mask acid regurgitation, skin problems (itching, rash) or GI
of active benign gastric the symptoms of other constipation, diarrhea, effects (nausea, diarrhea, vomiting,
Therapeutic Effects: ulcer. Pathologic gastric disease. Caution flatulence, nausea, constipation, heartburn, flatulence,
Diminished hypersecretory should be exercised in vomiting. abdominal pain).
accumulation of acid in conditions, including patients with hepatic Derm: itching, rash.
the gastric lumen with Zollinger-Ellison impairment. Misc: allergic reactions. Monitor improvements in GI
lessened syndrome. Reduction symptoms (gastritis, heartburn, and so
gastroesophageal of risk of GI bleeding in forth) to help determine if drug
reflux. Healing of critically ill patients. therapy is successful.
duodenal ulcers. OTC: Heartburn
occurring ≥ twice/wk. Assess dizziness that might affect gait,
balance, and other functional
activities. Report balance problems
and functional limitations to the
physician, and caution the patient and
family/caregivers to guard against falls
and trauma.

Monitor other CNS side effects

(drowsiness, fatigue, weakness,
headache), and report severe or
prolonged effects.

Monitor any chest pain and attempt

to determine if pain is drug induced or
caused by cardiovascular dysfunction
(e.g., angina that occurs during
exercise).