Aa - LMR Georgette - Final Version
Topics covered
Aa - LMR Georgette - Final Version
Topics covered
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o Least
Lest Weight Gain Antipsychotics:
Latuda (Lurasidone)
Abilify (Aripiprazole) – also least sedating
Geodon (Ziprasidone)
If pt presented with a 1st psychotic episode – use atypical antipsychotic (less EPS), especially IMs:
Invega (Paliperidone)
Olanzapine (Zyprexa)
Abilify (Aripiprazole)
Geodon (Ziprasidone)
HEPATOTOXIC DRUGS:
(Hypotonia)
Depakote (50 – 125) Toxic > 150
Spina Bifida / Neural Tubes Defects (TERATOGENIC)
Hepatotoxicity
RUQ Pain
Reddish brown urine
Complete LFT
When toxic (Confusion, Lethargy, Resp Depression, Disorientation)
If Toxicity:
o D/C;
o Check Valproic Acid Levels.
o Check Ammonia Levels.
o LFT
TCA
Hepatotoxic.
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Lamotrigine (Lamictal)
Can cause Steven Johnson Syndrome (SJS)
Cause the less weight gain among the Mood stabilizers.
Clozapine (Clozaril)
Can cause Agranulocytosis
If ANC < 1000 = D/C even if the pt is no showing S/S of infections.
Monitor for S/S of Infections (sore throat, fever, fatigue, chills)
Decrease Suicide Ideations in pts with schizophrenia
Always check HCG in females (12 – 51 years) before starting Mood Stabilizers.
Check TSH
Creatinine (0.6 – 1.2)
BUN (10-20)
Urinalysis (check for proteins, 4+)
Neuroprotective treatment for Bipolar Disorder (protect nerve cells from damage)
Gold Standard for treatment in Bipolar
Decrease Suicide Ideations in BD
Can cause Epstein Anomaly – especially during the 1st trimester.
Meds that can increase Lithium Levels (by reducing renal clearance):
NSAIDs (ibuprofen; naproxen; diclofenac; celecoxib; indomethacin; high-dose aspirin)
Thiazides (Chlorothiazide; Chlorthalidone; Hydrochlorothiazide).
ACE-Is (Captopril; Enalapril; Lisinopril)
Dehydration
Side Effects:
Leukocytosis (High white blood cell count)
Hypothyroidism
Maculopapular rash
T-Wave Inversion. - Do EKG if > 50 y/o.
Fine hand tremors
If Coarse hand tremors = Toxicity.
GI upset (Nausea, Vomiting, Diarrhea, Anorexia) – monitor pt closely for toxicity.
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Drowsiness
o 1st D/C
o 2nd Check Lithium levels
If Pt goes to the Gym a lot – presents reddish/cherry urine – check for Myoglobinuria.
SSRI is 1st Line Treatment for depression bc is safer in OD.
If pt is depressed + cancer = SSRI (Citalopram, Escitalopram bc of the less potential of drug-to-drug interactions)
SSRI = Sexual problems
If depressed, and wants to avoid sexual problems = NDRI (Wellbutrin)
If depressed + Low energy/fatigue = NDRI (Wellbutrin)
If depressed + Neuropathic Pain = SNRI (Duloxetine)
1st Line of Treatment for Neuropathic Pain:
o SNRI
o TCA
o Gabapentin / Pregabalin *[alpha-2 delta ligand]
Antidepressant Black Box Warning in children, teens and young adults – SI (assess for SI, frequency and severity).
If depressed pt – assess for alcohol intake bc they might be “self-medicating” with alcohol.
Little evidence of antidepressants in children Vs. Adults – Children had a less placebo rate.
SCHIZOPHRENIA
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Can cause aggression DSM-5 not longer uses the speci ers:
1- Paranoid
Impulsivity 2- Disorganized
3- Undifferentiated
Abstract thinking problems
Only remains:
1- Catatonia
2- Currently in partial remision.
Thought Process: Assess how organized are the thoughts / if they are logical / normal or abnormal
o Tangential (never getting to the point / moving from topic to topic)
o Circumstantial (the pt goes in Circles, providing unnecessary details before getting to the point)
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DEPRESSION / MANIA / PSYCHOSIS
Inducing meds
after
- Start only 12 hrs stopping alcohol intake / No alcohol-containing products for 2 weeks after D/C
treatment / Increases the LFT.
- Disul ram Increases Warfarin (Coumadin) levels - increasing the risk of bleeding.
2D6
Other Inhibitors:
*Grapefruit Juice
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Paradoxical Effect = the medication is causing the oppositive effect of the expected result – avoid this medication
in the future.
Apoptosis – neuronal loss / cell death.
BIPOLAR DISORDER
self-esteem
Pressure speech / difficult to interrupt
Irritability
Uncooperative
Sudden onset of Neurological Symptoms after a stressful experience (death, loss, etc.):
o Paralysis
o Mutism
o Blindness
o Paresthesia (numbness, tingling)
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ADJUSTMENT DISORDER (AD)
Onset of Emotional / Behavioral Symptoms (within 3 months) after a stressful experience (death, loss, etc.):
o Depression
Modi ers o Anxiety
o Mixed
o Disturbed of Emotions and Conduct:
• Common in children (e.g., after moving out from home; divorce of parents; recent loss of the pet; etc.)
• Presentation: Crying all the time; Insomnia; Peer Conflicts; Verbal Altercations; Truancy.
AD Vs. MDD
Adjustment Disorder – Has an identified Stressor - Only 2 symptoms of depression / Acute
Major Depressive Disorder – Does not have an identified Stressor.≥ 5 symptoms of depression / Chronic
FACTITIOUS DISORDER
CONDUCT DISORDER
*Persistent behavior that violates the rights of others, social norms, rules.
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ADHD
We can see Tics in OCD and Tourette’s, but in Tourette’s there are no intrusive thoughts.
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6. The pt cannot resist aggressive impulse.
7. This could result in serious attacks / destruction of property
8. Typically followed by guilt / remorse
✤ Use SSRIs, or Lithium / CBZ for refractory // or B-Blockers
✤ DO NOT Use Venlafaxine
skills
RETT SYNDROME
Development of specific deficits following a period of normal functioning after birth.
**Common in Girls
Onset of symptoms after 5-7 months of normal development.
Small head growth
Loss of acquired hand skills - stereotyped hand movements.
Poor social engagement
Seizures
Irregular respirations
Scoliosis
Flatt affect.
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POST-TRAUMATIC STRESS DISORDER
PTSD
Intrusive re-experiencing of the traumatic event Acute 1-3 Months
Chronic ≥ 3 Months
Increased arousal (hyper arousal) Delayed > 6 months.
Avoidance
Nightmares – use Prazosin for this.
CBT, Exposure Therapy & Response Prevention; Supportive Group Therapy —Goal of Therapy: Adaptive resolution.
FDA-SSRI: Paroxetine, Sertraline - If ashbacks - antipsychotics (Shapiro)
Avoid exacerbation of symptoms:
o Assessment (Collect Data) by completing Exposure; Discuss Fears.
No BNZs
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DELIRIUM
DEMENTIA
Chronic (months to years)
Progressive declining of cognitive status
Irritability
Personality Changes
If suspected Dementia check:
o Folic Acid Levels
o Vitamin B12 Levels
TYPES OF DEMENTIA
You are getting a new pt that uses IV drugs and is presenting HIV-Related Dementia signs and symptoms – order
HIV test.
If HIV-Related Dementia – Treatment is with Antiretrovirals.
PSEUDODEMENTIA
Present visual hallucinations. - Also presents Parkinson Features (Bradykenisia, Rigidity, Tremors) - No treat with A.Psy. Meds
SOCIAL JUSTICE
Provide Services to the ones who need them the most, but don’t have access
access to it: to it.
1. Sometimes is at micro level (e.g., care for a # of pt pro-bono each year; volunteer at Mission Clinics in the Community)
2. Sometimes is at macro level (e.g., working with a group to effect health law change, trying to make it an Universal Right)
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Pts that lives in rural areas, especially in houses from the ‘70s could be at high risk of lead poisoning
If taking care of infant that is about to die – give infant to parent so they can grief the loss.
THERAPIES
Cognitive Therapy:
o Replace irrational thoughts / automatic negative thoughts for more acceptable/positive ones.
Behavioral Therapy:
o Teach Behavioral Techniques:
o Problem-Solving
o Skill Training
o Muscle Relaxation
o Exposure
o Modeling
If doing Group Therapy and the pt is uncomfortable sharing his problems in the group setting, but NP wants to
promote Interpersonal Learning (he needs to be part of the group):
o Encourage pt to continue with Group Therapy
o Provide Adjunctive Individual Therapy – to facilitate group involvement.
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Interpersonal Therapy
For Interpersonal Issues (problems when socializing with other – problems at work, school, home)
For marital conflicts / relationship problems
Last 12-16 weeks. Time-Limited
Strategic Therapy
Problem-focused
Symptom-focused
Paradoxical Directive / Paradoxical Intervention / Paradoxical Strategy (Inversed Psychology).
Straight Forward Directive
Reframe Belief System.
When education pts about Medication – also teach about muscle relaxation
Exercise Program / Physical Activity in children improves body image:
o Self-esteem
o Self-Awareness
o Self-worth
o Promote resilience
o Improve Relationships
o Improve Social Anxiety.
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If appointment for Couple Therapy, but only one spouse shows up = reschedule the app until both can be
present.
If pt is moving out of state, and if there is no imminent danger/risk, provide patient with enough medication until
he finds a new provider (2-3 months).
Mother call NP informing that her 5 years old was sodomized/molested/abused by her 15 years old:
o Request mother not to leave the 5 y/o alone with the brother again
o Call CPS
o Organize / schedule Family Crisis Therapy / Counseling.
If pt presents Rheumatoid Arthritis (RA) – check of Erythrocytes Sedimentation Rates Levels (ESR Levels).
Is normal to 3-6 years old to play with the gentiles – Phallic Stage
Normal to masturbate
Grief response varies depending on the person – there are no standard guidelines on how someone is supposed
to grief.
While pt grieving, NP doesn’t provide Prescriptive Advice (you don’t tell him how to grief, e.g.: “Stop going to
school so you can process you pain.” “Get extra busy so you don’t think about your loss.”).
To normalize Grief and Loss in Children:
o The most important is to guarantee an Intact Family System.
o Group Therapy so the child can learn from other children with similar losses
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Increase Mental Health Access to needed people (e.g., OB clinic)
Grasp/Palmar reflex (normal up to 6 months) – if reflex persist > 6 months, this is an abnormal finding.
Moro Reflex / Startle (normal up to 6 months)
Babinski / Plantar Reflex (normal up to 2 years) – fanning out the toes.
PDE5 Class of medication – For Sexual Dysfunction (e.g., Viagra) – They are rapidly absorbed after PO
administration
Normocytic Macrocytic Anemia – check for Folic Acid, Vitamin B12, and Iron Levels
Only refer if there is nothing you can do (within the scope of practice). Always select something you can DO as
PMHNP (e.g., drug screening).
HABEAS CORPUS
o Legal concept that protects pts against unlawful hospitalization.
o Protects pt’s rights.
o The pt can use this concept to leave against medical advice (LAMA)
When Dx a pt, and trying to review a specific timeframe / timeline, but the pt doesn’t remember:
o Ask specific questions to anchor the memory
o Ask specific questions about memorable events
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NP trying to create a new Policy, but need information from other PMHNPs:
o Host online form / survey where
when PMHNP can go an enter their responses.
NP trying to create a new Policy in a specific facility, but the coworkers/colleagues are against the new policy.
How to convince them about the importance of this new policy?
o Educate in how this new policy is going to improve the outcome of quality in pt care.
o Explain the benefits of this new policy.
When there is conflict of interest btw pharmaceutical companies and the PMHNPs; these companies are
promising to sponsor for the NPs studies if they use their product (medication). The PMHNP want to create a
new policy that address this conflict of interest:
o 1st assess the relationship btw the Industry Provided Samples and the Industry Sponsored Education.
This pt was started on medication “X”, but he went online and found there is a Black Box Warning for this
medication. The PMHNP next action is to research the Benefits and Risks of Continuing administration of this
medication.
When using a medication for Off-Label Use, Documentation is very important. Document a Full Disclosure,
documenting risks and benefits of the medication (e.g., Trazodone is an antidepressant, but it could also be used
for insomnia. This medication can cause priapism)
SEVERE 0-
MODERATE 10-2
MILD 21-2
NORMAL 25-30
ANXIETY
FDA-approved for Alcohol Disorder: Acamprosate (Campral) / Disul ram (Antabuse) / Naltrexone (Vivitrol)
General health maintenance medication to treat vitamin deficiencies in persons with alcohol dependence include thiamine, folic
acid, and B-complex vitamins.
With the COWS, if Mild, the PMHNP can:
o Prescribe Clonidine
With the COWS, if Moderate, the PMHNP can start with scheduled medication:
o Prescribe Buprenorphine or Suboxone (sublingual medication)
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o Ativan
If the pt has a liver disease, and he is withdrawing from alcohol, give only “Out The Liver”:
o Oxazepam
o Temazepam
o Lorazepam (Ativan)
If PMHNP receives a pregnant pt withdrawing from alcohol / substance = Priority action is to send this pt to a
Residential Treatment Center for detoxication with Addiction Specialist and OB.
No BNZs for anxiety + alcohol/drug withdrawal symptoms = Rx Buspirone or Vistaril and refer pt to Residential
Treatment Center.
IRVIN YALOM
Focus on the strength of the organization, on what the employees are doing right.
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Reflective Practice:
o The goal is to improve practice.
o Reflect about incidents
o Gain Insight about incidents
o Enhances critical thinking to problem-solve, and decision-making.
o When there is an incident on the unit, and you’re a team leader, it’s important to provide feedback to
improve practice.
o Use Debriefing strategies techniques.
Verify - Correc
States Board of Nursing Report - Incorrect
dictates what you can do or can’t do (scope of practice)
When there are answer options that require the NP to Verify information with the State Board of Nursing, most
of the time are Correct.
If the PMHNP wants to do TMS, and he is not sure, he would have to verify with the State Board of Nursing.
When there are answer options that require the NP to Report someone with the State Board of Nursing, most of
the time are Incorrect.
Standard of Practice
Quality of care provided to the patient.
Protocols and guidelines to follow are determined by ANA
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When disclosing Psychiatric information and Substance Abuse / Chemical Information, the PMHNP needs two
separate Signed Informed Consents.
If the pt is unable to provide Informed Consent, but he is not a danger to himself or others, Assess for possible
Involuntary Treatment.
Nonmaleficence – Prevents Imminent Danger (e.g., pt wis long hx of substance abuse and is requesting BNZs =
do not Rx BNZs bc of risk of relapse – Doing no Harm)
Beneficence – Do what is right to the pt (e.g., depressed pt needing treatment = Initiating treatment with SSRIs –
Doing what it right for the pt)
Patient’s Rights:
o Lest Restrictive environment.
o Confidentiality
o Give / withdraw informed consent
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A, B, C are Interventions, D is the only Assessment. (Assessment 1st)
Just Culture – Is about Patient’s Safety (e.g., after a nurse error, the 1st action of the PMHNP is to make sure that
the pt is safe after this error; Then further steps: report incident, the nurse, etc.)
(E.g., nd the error, and identify what went wrong.)
C – There is strength in numbers! – If PMHNP wants to develop and advocate for policy is needed support from
other NPs, and joining a professional association.
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D – Stigma can be shown as Shame
One of the Best ways to reduce Stigma regarding Mental Illness is through Education.
To reduce stigma always target the largest/broadest populations through TV, Radio, Newspapers.
A – Autonomy (the pt has the right of Self-Determination / refuse treatment – as long he is not in Imminent
Danger)
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RECOVERY MODEL
Focus is on skills, abilities, interests
Self-direction
o The pt has Autonomy.
o the pt reports in what areas he needs help.
o pt has control over the resources.
Individualized care.
Non-Linear:
o Learning for experience
o Use relapse as learning opportunities.
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If you get a woman informing that she just got a message from her husband informing that he wants to commit
suicide. The PMHNP steps are:
o Ask for the husband’s current location
o Notify the Police / Crisis Unit
Erickson’s Stages
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The Highest Risk Factor for Suicide is a Previous Suicide Attempt.
CONFIDENCE INTERVALS
Small Sample Size Fewer # of outcomes events Less Precision in estimate of Effect Wider Con dence Interval
If a Sample Size is too small, the the Study will have insuf cient Power to detect differences between the groups. This could
lead
Type Ito a Type
Error is the II error (when
mistaken rejectioninvestigator
of an actually falsely
true null reject the(also
hypothesis null known
hypothesis [p-value
as a "false positive"> nding
0.05]orand conclude there is no
conclusion.
relationship
Type II Error is btw the variables,
the mistaken acceptance when
of aninactually
fact, there is one).
false null Type
hypothesis I Error
(also known- When
When there
there
as a "false is no
is no
negative" a relation,
relationship, but
nding orbut investigator
the saysYes
Investigator says
conclusion. no.
Law: “What has to be done” “What you can/ can’t do”- De ned by the The State Statues on Nursing
Policy: “How it will be done”
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APPRECIATIVE INQUIRY (AI) [5 Ds Process]
The Scope and Standards of Practice for Nursing Administration describes Appreciative Inquiry (AI)
as a framework for nursing leadership.
AI is the study of human systems when they function at their best by asking questions in a positive
way to identify what is at the core of success.
AI build organizations in what works, rather on trying to x what it does not work.
AI is an organizational change strategy that directs attention from failures and focus on potential
and positive elements.
1 DEFINITION
2 DISCOVERY - Identify the problem
3 DREAM - analyze the problem
4 DESIGN - generate solutions
5 DESTINY - implement best outcomes.
Resuming: People will receive the same money for treatment of mental health conditions, that
they would receive for physical health conditions / surgical procedures.
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DOPAMINE PATHWAYS
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Typical Antipsychotics D2 Receptor Inhibitors
Haloperidol
Chlorpromazine
Flufenazine
Thioridazine
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EXTRAPYRAMIDAL SIDE EFFECTS (EPS)
Looks like anxiety Use the Barres Akathisia Rating Scale or EPD Rating
Scale
Propranolol
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Reglan: Antiemetic and Gut motility stimulator
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ATYPICAL ANTIPSYCHOTIC MEDICATION Block D2 + Serotonin (5HT2a)
1. Risperidone (Risperdal)
2. Quetiapine (Seroquel)
3. Olanzapine (Zyprexa)
4. Clozapine (Clozaril)
5. Ziprasinone (Geodon)
6. Aripripazole (Abilify) - Can cause visual hallucinations.
7. Lurasidone (Latuda) - Have with food that contains at least 350 calories to increase the absorption.
8. Paliperidone (Invega)
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Highest
Highest HI.HI.
Highest
Highest HI.SI
Classic Symptoms
of Social Anxiety
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Contraindicated if Suicidal Ideations
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AREAS / FUNCTIONS OF THE BRAIN
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(REGULATES BODY FUNCTIONS) (SENSORY STATION)
Homeostatic
Functions
(MEMORY) (EMOTIONS/FEAR)
(MOVEMENT)
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(RN is the most involved circuit in anxiety disorders)
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ID “I Want
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/ Constancy
Magical thinking
2
Beginning of Logical Thinking
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Types of Crisis
1- Situational: deaths, changes in employment / nances, relationship status,
illness, suicide.
(These crises are seen as part of life)
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