Science 10 3rd Quarter Summative Test # 4 (S10LTIIId-37/ S10LTIIIe-38)
Explain how protein is made using information from DNA.
Explain how mutations may cause changes in the structure and function of a protein.
Name: ____________________________________________ Score: _______________________
Section: ____________________ Date: _______________________
I. Directions: Multiple Choices: Read the statements or questions carefully and then write the letter
(capital letters only) of the correct answer from the choices in your quiz notebook.
_____1. Where is the site of protein synthesis in the cell?
A. Centrioles B. Chromosome C. Nucleus D. Ribosome
_____2. Which of the following is the first step in protein synthesis where information from the DNA is
coded into messenger RNA?
A. transcription B. Translations C. Replication D. Transportation
_____3. Which is NOT necessary for protein synthesis to occur once transcription is completed?
A. tRNA B. Ribosomes C. mRNA D. DNA
_____4. The anticodon of tRNA binds to __________.
A. an mRNA codon B. an amino acid C. the DNA D. rRNA
_____5. Which site (?) of the tRNA molecule binds to the mRNA molecule?
A. Amino acid B. Anticodon C. Codon D.5 prime end
_____6. The first step in translation is the binding of __________.
A. two ribosomal subunits to each other
B. mRNA to the two ribosomal subunits
C. tRNA to the small ribosomal subunit
D. mRNA to the small ribosomal subunit
_____7. Which amino acid starts all protein synthesis?
A. Glycine B. Methionine C. Proline D. Thymine
_____8. Which RNA binds to an amino acid?
A. mRNA B. tRNA C. rRNA D. hnRNA
_____9. How many base/s of nucleic acid determine a single amino acid?
A. Four B. One C. Two D. Three
_____10. Which is required for protein synthesis?
A. tRNA B. mRNA C. rRNA D. All of these
_____11. Supposedly the DNA base sequence is TAG GCA CTG, what will be the base sequence in
messenger RNA?
A. AUC CGU GAC B. AUG GCU GAG C. AUC CGU GUC D. CUA UGU UGC
_____12. What will be the chain of amino acids that will be produced in protein synthesis if the mRNA
codon is AUG CGU UGC?
A. asp-his-tyr B. leu-phe-lys C. met-arg-cys D. pro-ser-val
_____13. The ultimate source of genetic variation is __________.
A. nucleic acid B. mutation C. genes D. chromosomes
_____14. What disease is caused by bleeding due to reduced activity of protein need for blood clotting?
A. Hemophilia A C. Sickle-cell anemia
B. Marfan syndrome D. Vitamin D resistant rickets
_____15. In mutational event, what happens when adenine is replaced by guanine?
A. Insertion C. Point Mutation
B. Inversion D. Substitution
_____16. Which will be most likely to happen because of mutation in a person’s skin cells due to too much
radiation from the sun?
A. albinism C. dark colored skin
B. light colored skin D. skin cancer
_____17. What is a mutagen? A mutagen is a/an __________.
A. inhibitor gene modification
B. enzyme that repairs mutation
C. chemical or physical agent that induces mutation
D. molecule which stabilizes DNA thus prevents mutations from occurring
_____18. The DNA was mutated to CCTGAC but the original DNA is CAGTCC, what type of mutation took
place?
A. Deletion B. Insertion C. Inversion D. Point mutation
_____19. If the amino acid threonine (ACG) was replaced by aspartic acid (GAC), this is an example of
which type of mutation?
A. Deletion B. Insertion C. Inversion D. Point mutation
_____20. This genetic disorder is caused by an extra copy of chromosome 21(trisomy 21) characterized by
decreased muscle tone, stockier build, asymmetrical skull, slanting eyes and mild to moderate
mental retardation.
A. Down’s syndrome C. Klinefelter’s syndrome
B. Jacobsen syndrome D. Turner’s syndrome
Prepared by: Checked by:
KRISTOPHER C. MIRANDA,PhD REVELYN C. CAMACHO,PhD
MT-I HT-VI, Science Dept.
