The West Bengal University of Health Sciences f 2nd Professional BDS December, 2020-January, 2021 Examination Subject: General and Dental Pharmacology and Therapeutics Time: 3 Hours Full Marks: 70 Group-A 1, a) Enumerate Antitypertensive drugs. Outline the management of Hypertensive emergency. Mention the adverse effects of ACE (Angiotensin Conerting Enzyme) inhibitors. — 4+4#2 or b) Enumerate dugs used in Angina pectoris. Outline the mechanism of action of nitrates. Describe the management of uncomplicated Myocardial infraction. atl 2. Write short notes on (amy five) : Sx4 a) Tinidazole. b) Fluorides, ©) Rifarnpicin. d) Disclosing Agents. ©) Albendazole, 1) Lignocaine as local anaesthetics, 3. Choose the correct answer: Sxt a) One of the following drug undergo Zero order kinetics : i) Alcohol ii) Paracetamol. {ii) Valproic Acid, iv) Alprazolam, b) Which of the following is used in the prophylaxis of angina pectoris : i) Propranolol, if) Atropine. iii) Methotrexate. iv) Lignocaine. ©) Which of the following is used in the treatment of Anaphylaxis: i) Glyceryl trinitrate. ii), Metoprofot, iii) Adrenaline. iv) Nifedipine. 4) One of the drug is used in treatment of peptic ulcer : i) Aspirin, ii) Omeprazole, fii) Phenytion sodium, iv) Regular insulin. 0) ‘Which of the following is neuro-muscular blocker? Ibuprofen. ffi) Thiopenton Sodium. iv) TSuccinyl Choline. BT. i) Tecrine.Group-8 ~) fa) Enumerate General Anaesthetic Agent. Outline the advantages and disadvantages of halothane as a general anaesthetic. 4 or b) Enumerate Aminoglycoside antibiotics. Mention the common properties and adverse effects Q of uminoglycosides. Mention the uses of Streptomyein 3434242 |. Write short notes (any five) : Sx4 a) Plasma half-life. b) Warfarin, ©} Hy- receptor blocker. d) Dentifrices. ©) Lignoeaine as local annesthetics. 1) Tachyphylaxis. 3. Choose the correct answer : Sxl a) The Opioid antagonist used to treat morphine poisoning is: i) Nalorphine, ii) Nalbuphine, iii) Naloxone. iv) Naltrexone. b) Which of the following is a Pro-drug : ji i) Dipivetrine. ii) Lisinoprt. iii) Ipratropium, iv) Glycopyrrolate. ©) Which one of the following is not a catecholamine : i) Adrenaline, ii) Histamine. tii) Dopamine, iv) Isoprenatine. 4) All of the following are used as dental restorative material, except: i) Gold Alloy. i) Titanium, ii) Mercury. iv) Silver amalgam, Which one of the following drugs is not ef¥estive in candidiasis: i) Itraconazole. fi) Nystatin. ii) Griseofulvin. iv) Amphotericin-B.be i The West Bengal University of Health Scien 2) 2nd Professional BDS February- March, 2020 Exami Subject: General and Dental Pharmacology and Therapeutics % Time: 3 Hours Full Marks: 70 Group-A a) Mention different sources of drugs with examples. Name four drugs obtained from plant sources. Mention two advantages and two disadvantages of administering drugs through intravenous route. 4244 or b) Enumerate alpha blockers, Mention theripeutic uses of alpha blockers. How will you manage a case of pheochromocytoma? 34364 . Write short notes on (any five) : Sx4 @) Dopamine (Mechanism of action, uses). b) Losartan (uses, side effects), ©) Heparin (Mechanism of action, uses). d) Sucralfate (Mechanism of action, uses). €) Streptokimase (uses side effects) 9 Plasma half life (Definition, cinical significance). |. Choose the correct answer: Sxl a) Enalapril is contraindicated in: i) Pregnancy. if) Hypertension. iii) Diabetic nephropathy. iv) Heart failure. b) Adrenaline is drug of choice in; i) Chronic heart failure. ii) Pheochromocytoma. iii) Bronchial asthma. iv) Anaphylactic shock. ©) Pantoprazole blocks: i) Na"K* diffusion. ii) H°K" ATPase pump. iii) L type ealeium channel. iv) NCX. 4) Following is a component of ORS: i) Sodium chloride. ii) Magnesium chloride. iii) Zine oxide. ix) Atropine sulphate. ) Salbutamol is a selective agonist of: i) Alpha; receptor. fi) Betayreceptor, _—ili) Hj receptor. iv) SHT receptor. P.T. 0.4. a) Classify beta lactam antibiotics. Write down the mechanism of action of penicillin. Mer b) Classify antithyroid drugs. Write down the mechanism of action of propyithiouracil, Group-B the uses of cephalosporins. or Mention the indications and side effects of radioactive iodine. 5. Write short notes (amy five): a) » ¢) d) e) b) Lignocaine ( Mechanism of action, uses). Phenytoin (Uses, side effects) Tiotropium bromide (Mechanism of action & uses). Gentamicin (Uses side effects) Regular insulin (Uses, side effects) First line antitubercular drugs (Name & side effects) 6. Choose the correct answer : a) b) °) d) 9 Following is an inhalational anaesthetic: i) Ketamine. i) Propofol. iii) Desflurane. Foliowing is an antidiabetic agent: i) Atropine. ii) Permethrin. iii) Sitagliptin, Following is not a protein synthesis inhibitor: i) Chloramohenicol. ii) Amikacin. iii) Amoxicillin, Weight gain is a side effect of i) Metformin. li) Orlistat. iii) Olanzapine. Miosis is an effect of i) Phenylephrine, ii) Morphine. _ii) Tropicamide, dears Sx4 5x1 iv) Thiopentone. iv) Rifampicin. iv) Azithromycin. iv) Omeprazole. iv) Tamsulosin.2/19 The West Bengal University of Health Sciences and Professional BDS August, 2019 Examination Subject: General and Dental "harmacology and Therapeutics Full Marks: 70 ‘The 3 Hess Use separate attswer seript for each groap . Group-A 1, a) Enumerate different opioid analgesics, Write different indications and contraindications of moephine 343 or Enumerate different NSAIDs. Mention mechanism of action of aspirin as analgesic and anti-inflaitinatory drug, Write different clinical uses of aspirin, 34443 2. Write short notes on (any five) ; 5x4 19 Inpalational route of drug administration, pf Yssential drug. ~ ‘Volume of distribution. ‘Topical application of analgesics. e) Fixed dose combination of drugs. 2 ramadot. 3. Choose the correct answer: Sx a) Allare used in prevention of bronchial asthma except: i) Theophylline. Steroids. il) Montelukast. JyGosin cromoglycate, b) Adrenaline is combined with local anaesthetics due to all except: i) Prolong duration of anaesthesia. _ il) Reduces biceding, iit) Less systemic toxicity. “ah Good tissue heating, ©) Whieh of the following is ai Lv anaesthetic: \W Ketamine. i) 0. ili) Ether. jy) Halothane, 4) Dopamine can be used in: i) Epilepsy. Ji) As pte anacsrthetic medication. Hii) Kenal ischemia, Parkligonisn, ©) Which of the following is used as pre anaesthetic medications exeept: RY Glycopyrrolate, ii) Diazepam. il) Pantoprazots. pb Adesnatine, ro,Group-B 4. A Enumerate different Muroquinolone (FQ). Mention the mechanism of action fluroquinolones as antibiotic. Write the clinical uses of FQ. 2td+4 or b) Enumerate diuretic drugs according to their site of action. Mention the mechanism of action of furosemide. What are the different clinical uses of furosemide? 44343 §. Write short notes (any five) : Sx4 Gay Azithromycin (Mechanism of action, use & adverse effects). Sucralfate (Mechanism of action & uses). Cotrimoxazole (Mechanism of action & uses). wa Clavulanic acid (Mechanism of action & uses). {67 Clotrimazole (Mechanism of action & uses). f) Nitroglycerine (Mechanism of action in angina & side effects) 6. Choose the correct answer : Sxt a) Which of the following is drug of choice in Diphtheria infection? i) Ceftriaxone. i-Levofloxacin. Penicillin. iv) Amikacin. b) Which ofthe following is a 5" generation cephalosporin? ) Cefixime. ii) Cefepime. iii) Cefotaxime. iy Ceftobiprotc. ce) Which of the following is anon elective beta receptor antagonist? 1) Bisoprotol. ii) Metoprolol. Wf Propranolol. iv) Atenolol, 4) Dabigaizan is preferred over warfarin due t0 5 1) Better patiem compliance. ii) Antidote available, ti) Less chance of bleeding. iv) Less costly. All of the following is a nucleoside zidovudine. ii) Efuyirenz. reverse transcriptase inhibitor except : ) Nevirapine. Maraviros,The West Bengal University of Health Sciences 7) BDS 2nd Professional Examination, 2018 Subject: General and Dental Pharmacology and Therapeutics ‘Time: 3 Hours Full Maries 70 Use separate answer script for each group: Growp-A 1. a) Enumerate local anaesthesia. Mention mechanism of action of Lignocaine as local anaesthetic, What are the adverse effeets of Lignocaine? a4et3 or b) Enumerate beta blockers. Mention their therapeutic uses & adverse effects. 44343 2. Write short notes on (amy five) ix a) Micro enzyme iniduetion. b) Dentsifices. ©) Styptics. 4) Propofol, ¢) Doxicyeline, f) Sumatriptan, 3. Choose the correct answer: Sxl a) Atropine is used in: i) ‘Organophosphorus poisoning, ii) Datura poisoning. iii) Morphine poisoning. iv) Strychnine poisoning. b) Selective cox-2 inhibitor is: i) Nimesulide. ii) Paracetamol, iii) Parecoxib, iv) Peroxicam. ¢) Which of the following is a prodrug? i) Enalapril. ii) Salbutarol. iii) Clonidine. iy) Acetazolamide. 4) Which of the following is not an antiepileptic: §) Valproic acid, il) Phenytoin. il) Chlorpromazine. iv) Ethosuximide ©} Which of the following is dopamine precursor : i) Levodope. ii) Benserazide. iii) Ropinitole, iv) Totcapone, P70, we IN Sface nn___\au gz Group-B & drugs. Mention the mechanism of action of Rifampicis, ut i ste, |. a) Enumerate anti-tubercular down the other user & adverse effect of Rifwmpicin. or hypertension, Mention the mechanism of action of Thiaxides ax ly used in hypertension. Be443 b) Enumerate the drug used in antihypertensive agent, Explain why loop diuretics are not routinel |. Write short notes (any five) + a) Warfarin (Mechanism, use & adverse effects). 1b) Proton pump inhibitors (Mechanism of action & uses). c) Aminoglycosides (Common features & side effects). d) Fluconazole (Mechanism of action & uses). 6) Halothane (Advantages, disadvantages & side effects), £) Dobutamine (Mechanism of action & uses). . Choose the correst answer: a) Which of the following is not an antiemetic agent. : i) Hyoseine. ii) Domperidone, iti) Bisacodyl. iv) Onidansetron. b) All of the following are 3” generation cephalosporin except: i) Cefixime. il) Cefadroxil. iii) Cefotaxime, fv) Ceftriaxone. ©) Which of the following is selective receptor antagonist: i) Yohimbine. ii) Clonidine. iii) Phenoxy benzamine. iv), Prazosin, 4) Rationale of Diuretic therapy in Heart Failure excludes: i) Reduce extra cellular volume. ii) Reduce preload. iti) Decrease heart rate. iv) Reduce Peripheral resistance. ©) Allof the following is antiretroviral agents except: i) Zidovudine. ii) Lamivudine. fii) Nevirapine. iv) Valacyclovir. f # dU Maa ea7 The West Bengal University of Health Sciences BDS 2nd Professional Examination, 2017 ‘Subject: General and Dental Pharmacology and Therapentics ‘Time: 3 Hours Pull Marks: 70 Use separate answer script for each group: Group-A 1. a) Enumerate different routes of administration of drugs. Mention the advantages and disadvantages of intravenous route of drug administration. 34443 or ») Enumerate the drugs used in peptic ulcer. Mention the mechanism of action and therapeutic uses of pantoprazole, 34443 2. Write short notes on (any five) 5x4 8) Lignocaine (uses, mechanism of ection). b) Dentrifices (Definition, Types). ©) Plasma Half life (Definition, significance). d)_Astringents (name, uses). ©) Vitamin K (uses, side effects). f) Furosemide (uses, side effects), 3. Identify the most appropriate response out of the multiple choices Sxl a) Which one is murifying agent : i) Gumacacia. i) Siivernitrate, ii) Paraform. —_—_iv) Fluoride. ) Gum hyperplasia is caused by : i) Phenytoin, if) Pantoprazole. —_— ii) Warfarin. iv) Phenobarbitone. ©) Which drug is preferred in the treatment of hypertension in pregnancy : i) Thiazide. if) Methyldopa, iii) Ramiptil. —_—_ iv) Propranolol. d) An antagonist : ji) Has no affinity to the receptor. i) Has affinity to the receptor but no intrinsic activity. iii) Fias affinity to the receptor and intrinsic activity. iv) Has affinity to the receptor and intrinsic activity less than full agonist Ciprofloxacin acts by inhibiting + i) Protein synthesis. ii) mRNA synthesis, iii) Cell wall synthesis. iv) DNA gyrase, PTO,és Group-B 4. a) Enumerate the drugs used in the treatment of Amoebinsis. State the mechanism of yo and therapeutic uses of Metronidazole. dan é or 4) Enumerate f~ lactam antibiotics, Mention the mechanism of action of penicillin. State why ‘clavulanic acid is combined with Amoxicillin? 44343 5. Write short notes (any five) : 5x4 4) ORS (composition and use). >) Touprofen (Mechanism of action, Adverse effect). ©) ACE inhibitors (Name, uses), 4) Chloroquine (Uses, adverse effects), ¢) Ketoconazole (use, Mechanism of action). ) Macrolide antibiotics (Name, tse). 6. Identify the most appropriate response out of the multiple choices. 5x1 4) Which of the following is adverse effect of atropine : i) Increased salivation. ii) Blurred vision. ili) Bradycardia, iv) Diaphoresis. b) ‘Which of the following local anaesthetics has long duration of action : i) Lignocaine. ii) Procaine. iil) Cooaine. iv) Bupivacaine. ©) Which one is Selective Cox 2 inhibitor : i) Paracetamol. ii) Etoricoxib, iii) Piroxicam, —iv) Aspirin. 4) Insulin is usually administered by : i) Oral route. fi) Subcutaneous route, if) Intramuscular route, iv) Intradermal route. Ive Gy receptor antagonist is : ii) Yohimbine, iv) j*henoxy benzamine.‘The West Bengal University of Health Sciences 7 BDS 2nd Professional (Supplementary) Examination, 201 Subject: General and Dental Pharmacology and ‘Therapeutics Full Marks: 70 Time: 3 Mowers Use separate answer script for each grow Group a) Enumerate NSAIDs, Mention the therapeutic uses und adverse effects of Diclofenac, | or b) Name the drugs used in the treatment of organo phosphorus poisoning. Name atropine substitutes and state their uses. 34443 . Write short notes on (any five) Sx a) Bioavailability (Definition, calculation). b) Metformin (Mechanism of action, use). c) Drug tolerance (Definition, Example), d) First pass metabolism (Definition, Example of drags having high first pass metabolism). ¢) Indications and contraindications of Morphine. f) Salbutamol (use, Adverse effects). . Identify the most appropriate response out of the multiple chaices = a) Protamine sulphate used as an antidote in = i) Aspirin poisoning. ii) Morphine poisoning. iii) Warfarin overdose. iv) Heparin overdose. b) Potassium sparing diuretic is : i) Ethacrynic acid. ii) Spironolactone. iti) Thiazide. iv) Furosemide. ¢) Platelet aggregation is inhibited by = i) Aspirin, ii) Nitrate. fi) Enalapril. iv) Nifedipine. d) Which of the following drug is H) receptor antagonist ; f) Sucralfate. ii) Pantoprazole. iil), Magnessium hydroxide. iv) Ranitidine. All of the following are antifungal agents except : i) Ketoconazole, ii) Secnidazote. iii) Fluconazole, iv) Grieseofulvin, PTO, )4 Th Growp-B 4.) Enimerate antiplatelet drugs. Mention their therapeutic ses. Explain why low dose aa. ‘should be stopped 7days before extraction of tooth. Beang or by Enumerate Aminoglycoside antibiotics, State therapeutic uses and adverse effects of gentamicin. eed S. Write short notes (any five) = Sx4 4) Prokinetic agents (Name, uses). b) Thiazide diuretics (uses, adverse effects), ©) Albendazole (uses, mechanism of action). d) Metronidazole (Uses, adverse effects). ¢) Fluoroquinolones (Name, uses). 1) Rifampicin (Uses, adverse effects). 6. Identify the most appropriate response out of the multiple choices. Sxl 8) Which of the following sympathomimeticsis used in the treatment of bronchial asthma = i) Formoterol. ii) Norepinephrine. iii) Methoxamine. iv) Dobutamine. b) Which of the following is Morphine antagonist: i) Tramadol. ii) Methadone, jij) Naloxone. iv) Pethidine, oO ‘Which of the following f blocker is used in the treatment of glaucoma : i) Propranolol. ii) Nadolol. iii) Timolol. iv) Metoprolol. 4%) Coniconterid may be used inthe fellowing conditions except: 1) Bronchial asthma. ii), Rheumatoid arthritis, li) Herpes Simplex keratitis, iv) Organ transplantation, O) ‘Drag used inthe weatment of microcytic hypochtonic anaem es 8) Femous sulphate i) Weefatin. . 41) Clopidogrel i) Vitamin Bi. ps 2nd sine 10H =S ey, 4: 2 > % The West Bengal University of Health Sciences BDS 2nd Professional Examination, 2016 Subject: General and Dental Pharmacology and Therapeutics ‘Time: 3 Hours Full Marks: 70 Use separate answer script for each group Group-A . a) Enumerate Anti-tubercular drugs. Mention the therapeutic uses, mechanism of action and adverse effects of Rifampicin, 3434242, or b) Enumerate the drugs used in bronchial asthma. Describe the management of a case of acute severe attack of bronchial asthma. What is the role of cortico-steroids in bronchial asthma? 47333 . Write short notes on (any five) : Sx4 a) Tetanus toxoid. b) Antiplaque drugs. ) Mummifying agents. 4) Calcitriol. ¢) Redistribution. f) Thiazide diuretics. Sxl Identify the most appropriate response out of the multiple choices ; a) Preferred calcium channel blocker in Angina Pectoris is : i) Verapamil. ii) Diltiazem, iii) Nimodipine. iv) Flunarazine. 'b) Sulphonamide used as antimalarial agent is : i) Silver sulphadiazine. ii) Sulphadoxin. iii) Sulphacetamide. iv) Sulfadiazine. ©) Potassium sparing diuretic is : i) Ethacrynie acid, ii) Thiazide. iii) Spironolactone. iv) Furosemide. d) | Which of the followings is both a and Bf antagonist : i) Yohimbine. | ii) Doxazosin. iii) Labetalol. iv) Atenolol. ¢) Second generation antihistaminic is : i) Triprolidine. ii) Azelastine, iii) Cyproheptadine. iv) Promethazine. P.T.O,Group-B 3 4. a) Enumerate anti icpileptic drugs. Mention the mechanism of action enjoin and adverse effects 0, 49343 or b etait ) Enumerate antimalarial drugs. Describe the management of a case of acute benign tertian Malaria? Why Primaquine is given daily in B. T. malaria and single dose in Faleiparum malaria? 4rae2 S. Welte short notes (any five) : a 8) Antiseptics, b) Mouth wash. : ¢) Disclosing agents. 4) Gentamicin. ©) Necstigaine, f) First order kinetics. Identify the most appropriate response out of the multiple choices. Sxl a) Ipratropium bromide is : i) Sympatholytic. ii) Anticholinergic . iii) Antiemetic, iv) Antipsychotic, b) Alcohol should not be comsumed with : i) Sulfonamide. ii) Clonidine. iii) Reserpine. iv) Metronidazole. ©) Grey Baby syndrome is caused by: i) INH. ii) Tetracycline. iii) Amoxycillin. iv) Chloramphenicol. 4) One of the followings is not an indication of Metronidazole : i) Amocbic dysentery. ii) Gingivitis. iii) HIV infection, iv) H. Pylori infection. ©) All are aminoglycosides except : i) Paromomyein. ii) Amphoterecin - B- iii) Amikacin. iv) Gentamicin.io The West Bengal University of Health Sciences BDS 2nd Professional (Supplementary) Examination, 2016 Subject: General and Dental Pharmacology and Therapeutics ‘Time: 3 Hours ‘Fall Marks: 70 Use separate answer script for each group Group-& 1. a) Classify Nonestorvidal Antivinflammatory Drugs (NSAIDS). Mention the mechanism of action and adverse effects of Aspirin. oats or b) Enumerate Local Anaesthetic agents, Describe the mechanism of action of Lignocaine. Mention the adverse eflects of Lignovaine 3ean3 2. Write short notes on (any five) : 5x4 a) Essential Medicine, b) Low molecular weight heparin, ©) Metronidazole, @) Fluorides in Dentistry. ) Competitive. antagonism. £) Stypties. appropriate response out of the multiple choices : 3x1 tion both in vitro and in vive seen with ii) Heparin . iv) Prowmine Zine Insulin following drugs are first line anti-tubercular drugs except i) Isoniazid ii) Moxifloxacin iti) Pyrazinamide iv) Rifampin c) Inverse Agonist of Benzodiazepine Receptor is ; i) Yemazepam. ii) Chiorazepate. Beta Carbolin. iv) Nitrazepam, d) ‘The drug always follow zero order Kinetics is i) Phenytoin, ii) Alcohol iii) Paracetamol —_ iv) Metronidazole ©) Which of the following is used in the manugement of Acute attack of Asthama i) Ketotifen ii) Montelukast iii) Formoterol iv) Salmeterol PTO,| = & a aq o ‘ Group-t 5 4. a) Bnumennte diferent insulin preparations, How will you manage a case OF Diab, Avaen Ketuticidasis, What is Insulin Resisiancc”? or 1b) Rnumérate antihypertetisive drugs. Describe the mechanism of action, therapeutic uses and adverse offocts of ACE tnhibitars. wee 5, Weite short notes (aay five) : Bx4 a) Obtundants. b) Dentittices, ©) Metoclopramide d) Ketoconazole #) Proton pump inhibitors f) Disinfectants. Sxl 6. Identify the most appropriate response out of the multiple choices > a) Acute Paracetamol poisoning is treated by + i) Glycine. Hi), N-Acety! Cysteine, iii) Taurine iv) Codeine. b) Drug used in inhalation route is i) Desflurane ii) Ketamine g iii) Thiopentone Sodium iv) Propofol f choice in Penicillin induced anaphylaxis is : p, ii) Adrenaline i iv) Cefixime 3 of ge Ly a Cig facin acts hy inhibiting : wd INA gyrase ii) Protein Synthesis. P iii) mRNA synthesis, iv) Cell Wall Synthesis, ©) Which of the following is an anti-material drug i) Zidovudine ii) Pyravinamide iti) Artesunate iv) Ketoconazole,re niversity of Health Sciences The West Bengal U ional Examination, 2015 f BDS 2nd Profess' ae, f Subject: General and Dental Pharmacology and Therapeutics > spime: 3 Hours Full Marks: 70 Use separate answer script for each group Group-A 1. a) Bnumerate the diuretic drugs. Mention. the mechanism of action, therapeutic uses and adverse effects: of Frusemide. 3434242 or b) Enumerate the different routes of administration of drtigs. Mention advantages and disadvantages of oral route of drug administration. 443+3: 2. Write short notes on (any five) : Sx4 a) Lidocaine. b) Plasma half life, ¢) Diclofenac. 4) Astringents ©) Dentriftices. f) Warfarin sodium. 3. Identify the most appropriate response out of the multiple choices: 3x1 a) Platelet aggregation is inhibited by: i) Aspirin. + ii) Nitrate. iii) Enalapril. iv) Nifedipine. b) Gum hyperplasia is caused by: i) Pantoprazole. ii) Phenytoin.. iii) Warfarin. iv) Pilocarpine. ¢) Which one reverses the action of heparin: i) Atropine, ii) Vitamin K. ili) Protamine. iv) Adrenaline. 4) Which drug is used in hypertension in pregnancy: i) Divretics, ii) Methyldopa. iii) Ratmipril. iv) Propranolol. e) Which of the following is morphine antagonist: i) Tramadol. ii) Methadone. iii) Naloxone. iv) Pethidine. P.T.O.re Groupe 4. a) Enumerate P-lactam antibiotics, Mention the mechanism of action of penicillin, Why clauvulanic acid is combined with Amoxicillin. Wd or b) Enumerate atropine substitutes, Mention theripeutic ses of cael of them. SHS 5. Write short notes (any five) : 4) Co-trimoxazole, b) Ding resistance. ©) Fluorides in dental practice. a) Tinidazole, e) ORS. 1) Macrolide antibiotics. 6. Identify the most appropriate response out of the nvultiple choices. a) Famotidine acts by i) Hy receptor antagonisi. ii) Hy receptor antagonism. iii) Hj receptor agonism. iv) Proton pump inhibition. b) Which of the following local anaesthetic has long duration of action’? i) Lignocaine. ii) Procaine, iii) Covaine, iv) Bupivacaine. ©} Which one is selective COX-2 inhibitor? i) Paracetamol. ii) Etorieoxib. iii) Piroxicam. iv) Aspirin, 4) Insulin is usually administered by: i) Oral route, ii) Subcutancous route. lil) Intramuscatar route, iv) Intradermal route. ¥ Selective a receptor antagonist is - 1) Prazosin, thea, i) Yohimbine. iv) Phenoxybenzamine, ousS fai te é The West Bengal University of Health Sciences BDS 2nd Professional (Supplementary) Examination, 2015 ‘Subject: General and Dental Pharmaculogy and Therapentics ‘Tie: 3 Hours Full Marke: 70 Use separate answer script for each growp Group-A. 1. a) Enumerate anticoagulant drugs, Mention the mechanism of action, therapeutic uses and adverse effects of warfarin. 3434202 or b) Enumerate the drugs used in amoebiasis. Mention the mechanism of action and therapetitic uses of Metronidazole, wae 2. Write short notes on (any five) : x4 a) Metoclopramide. b) Ibuprofen, ©) Fluroquinolones. i) Sublingual route of drug administration. ce) Purgatives. f) Salbutamol. 3, Identify the most appropriate response out of the multiple choices: a) Drug of choice for acute attack of Angina pectoris is : i) Propranolol. ii) Glyceryl trinitrate, iii) Nifedipine. iv) Mannitol. b) Drug of choice in drug induced parkinsonism is: i) Levedopa. ii) Benzhexol. iii) Carbidopa, iv) Amantadine, ©) Chelating agent used in copper poisoning is: i) d—penicillamine. ii) Dimereaprol. iii) Succimer. iv) Unithiol. 4d) Diuretic used in glaucoma is: i) Thiazides ii) Frusemide. iii) Mannitol. _—_iv) Spironolactone. ©) Giardiasis is treated by: i) Ampicillin, ii) Erythromycin, _ iff) Metronidazole, iv) Albendazole. P.T.0.ee 4 a) Enumerate anti platclet drugs. Mention the mechanism of action and adverse effect, “ f 2 Group-B Aspirin. easy by) Enumerate oral anti diabetic drugs. Mention the mechanism of action and adverse effects ‘of sulfomylureas. wan 5. Write short notes (any five) = 5x4 a) Oral contraceptive pills. '») Spironolactone. ©) Allopurinol. @) Pantoprazole. e) Rifampicin. f) Tinidazole, 6. Identify the most appropriate response out of the multiple choices: 5x1 8) Adrenaline is combined with lignocaine: ’} To increase the duration of action. ii) To decrease the duration af action, ili) To increase bioavailability. iv) To decrease the onset of action, b) Specific antidote of organophosphorus poisoning is : i) Atropine. i) Pilocarpine. ili) Pralidoxime, iv) Physostigmine. ©) Drug of choice of anaphylactic shock is : i) Dobutamine. ii) Nor adrenaline, iii) Adrenatine. iv) Theophylline. d) Which one is Mast cell stabiliser: i) Codeine, ii) Methytxanthine, lil) Sodium chromoglycate. iv) Theophythine, ©) Which one is used iin drug induced vomitting : i) Metoclopramide, ii) Domperidone. iii) Hyoseine. iy) Ondansetron,The West Bengal University of Health Sciences BDS 2nd Professional Examination, 2014 { Subject: General and Dental Pharmacology and Therapeutics Time: 3 Hours Full Marks: 70 f | Use separate answer script for each group ! Group-A. J a) Classify NSAIDs. What are the therapeutic uses and adverse effects ra 44343 or \ b) lame the opioid alkaloids. What are the indications inti~contra indications of use of ‘Morphin? Ji ea Write short notés on (any five) : me 5x4 Peat 5} Bioavailability. i \erapeutiojindex. v4)" Management of status asthmatious e) PrazosinA-ap a Zomeprazotey 4 rir Oa Identify the most Semobsans Tesponse out of the multiple choices: Sxl ae apigapene uta not be donsumed with : ide. * ii) Clonidine. 6 Metronidazole. ©) Which is an uricosuric drug? i) Allopurinol. ol. i Probenecid robenecide, {9/ Omeprazole blocks : ' ots Indomethacin. iv) Aspirin. H+ K+:ATPase pump. ii) H+ Nat AT Pase Pump. iii) Na+K+ diffusion, ~ iv) None of the above. ©) Cardioselestive B- blocker is : i) Labetalol. —Litf~ Atenolol iii) Propranolol. iv) Sotalol P10.Group-B e agents. Describe briefly the drug therapy of oral candidiasis. Mention a : dt: the adverse effects of Amphoterecin B. 34443 or { fnumerate haemostatic agents. Describe the meghanism of action and adverse effects of 7 ~~ Warfarin. 2, 44343 Write short notes (any five) : - 2 Omidazole. ¢) Fluconazole, “b)_Post exposure prophyiaxis of a [/Bioglidazone,] r ©) Vitamin-K ° — f) Lowimolecular weight hepa ‘dentify the most appropriate response out ofthe multiple choices. 8) Drug of choice;in for digitalis induced arrhythmia i) Verapamil. Phenytoin. iii) Quinidine, | bY Froptnoot ) All are true about Chloramphenicol except: ay te Causes boo marrow suppression, ii) Used topically in conjunctivitis, iii) Useful in H. influenza meningitis. ° ivf Reserved for gram positive organism infection. is a Bot} we 2 —ue ©) Apratropium Bromide is an : ' i) Sympathelytic, HI Antichotinergic. 4) Metronidazole is ineffective in infection caused by : i i) Hpyfori : ii) Bacteroides, Doc wi LL Cryptosporidium parvum. iv) Giardia Kali ‘amsulosin is preferred in benign prostatic hypertrophy because : ot locker of alpha IA. i) Ithas short plasma half lize. Vi This a selective bi iii) Ithas severe effect on Blood pressure. Antiemetic, iy) Antipsychotic, ty iv) It is free from orthostatic hypotension, WW i ehS / The West Bengal University of Health Sciences %, /BDS 2nd Professional (Supplementary) Examination, 2014 Subject: General and Dental Pharmacology and Therapeutics 23 Hours Full Marks: 70 Use Separate answer script far each group _ Group-A + @) Enumerate drugs used in congestive cardiac failure. Enumerate the mechanism of action and adverse effect of any one of them, 4343 or b) Enumerate antiepileptic drugs. Describe the mechanism of action and adverse effect of phenytoin? aed 2. Write short notes on (amy five) : 5x4 8) Benzodiazepine. b) Chloguine. ©) Aspirin, 4) Calcitonin, ©) Metronidazole. ) Heparin. 3, Identify the most appropriate response out of the multiple choices : Sxl a) Thiazide diuretics are contraindicated in : " i) Rheumatoid arthritis. ii) Gouty arthritis. iii) Rheumatic carditis. iv) Osteo-arthritis. b) ACE inhibitors produce dry caugh due to : i) Direct stimulation of cough centre. ii) Increased PG production. iii) Inhibition of bradykinin degradation. iv) Increased level of angiotensin-} in plasma, €) Morphine causes vomiting by stimulating : i) Medullary centre. ii) Spinal cord. iii) Hypothalamus: iv) Chemoreceptor trigger zone. d) The plasma Walf life of drug determines = i) Standard dose. ii) Initial dose. ii?) Maximum dose. iv) Maintenance dose. ) Drug of choice in motion sickness : i) Metoclopramide. ii) Chlorpromazine. iti) Scopolamine, iy) Domperidone. P.T.O.- w Group-B . 8 4. a) Enumerate non steroidal anti- inflammatory agents. Explain- why low dose aspirin, a. prescribe in angina? Mention the adverse effect of aspirin, 3t3+6 or b) Enumerate antifungal agents. Describe briefly the drug therapy of oral candidiasis. Mention the adverse effects of Amphotericin -B, 34443 S. Write short notes (any five) : 5x4 a) Tinidazole. b) Rifampicin. ©) Metformin, d) Albendazole. ©) Streptokinase, f) Preparations of insulin, ®. Identify the most appropriate response out of the multiple choices, Sxl %) Drug of choice in penicillin induced anaphylaxis : ') Ligmocaine. ii) Phenytoin. ii) Adrenaline. b) Antidote for Organophosphorus compound poisoning is: i) Pralidoxime. ii) EDTA, ) Heparin. iv) Benzhexol, iv) Antihistaminic. ©) Low dose aspirin is used as : 1) Sympathelytic, ii) Anti inflammatory. iii) Antiometic. Metronidazole is ineflective in infection caused by : i) Ho pylon, fi) Bacteroides. 11) Cryptosporidium parvum, iv) Giardia lamblia, iv) Anti thrombotic, 4) ®) ‘The protease inhibitor used in AI1Ds : i) Neviraping, ii) Zidovudine, iii) Indinavir, iv) Stavudin,ga gttre a f Ma The West Bengal University of Health Sciences J BDS 2nd Professional Examination, 2013 Subject: General and Dental Pharmacology and Therapeut ape pew * Time: 3 Hours Use separate answer script for each group Group-A 8) What are the different routes of Drug administration? What are disadvantages of Intra-Venous route of Dig administration? What is meant by First-pass metabolism? ‘ +2242 or b) Enumerate the drugs used in hypertension, Describe the mechanism of action of beta blockers as anti hypertensive agents. Mention their therapeutic uses and adverse effects. 3438042 Write short notes on (any five) : 5x4 a) Redistribution of Drugs, b) Laxatives. ©) Half-life. ) Sublingual route of Deug administration. ©) Antibiotic Prophylaxis. f) Metronidazole. 2) Drugs used in anaerobic infection. "3, Identify the most appropriate response out of the multiple choiees : Sxl a) Which of the following is not a pro-drug : i) Levodopa. ii) Omeprazole, ii) Dipivefrin. iv) Promethazine b) Following are the inhalational glucocorticoids, except : i) Beclomethasone. ii) Betamethasone. iii) Fluticasone, iv) Flunisolide. ©) Preferred general anaesthetic for OPD surgery is: i) Lignocaine, if) Ketamine. ili) Thiopental. iv) Propofol. 4) Drug of choice in anaphylactic shock is: , . _ i) Noradrenaline. ii) Dopamine. iii) Adrenaline. iv) Salbutamol ) Ditwretic of choice in acute LVF is : i) Mannitol. ij) Furosemide. iii) Hydrochlorothiazide. iv) Acetazolamide. Pp. 7.0,Group-b UMENL OF HELE weve, no. Mention the treat bronchial asthe, ont i Mesa a8 ns drugs which can precipitate bronchial asthma. 2 WO, asthma, Name " oe 2 effects of = mechanism of action and adverse €! b) Enumerate local anaesthetics. Heseribe the mel hae Tignocaine. Sx4 5. Write shart motes (any five) : ; a) Levocetrizine, b) Ondansetron. ©) Warfurine. @) Proton pump inhibitors. ¢) Tinidazole, ) Anti-caries agent, g) Nasal decongestant, 6. Identify the most appropriate answer : 5x1 a) Allare true about gehtamicin, execpt : i) Oraladministration, il) Ototoxicity, lif) Nephrotoxicity. iv) Effective on gm (-)ve organism. 4) Allare trac about use of metronidazole, except : i) Gingivitis. ii) Amocbiasis. iii) Anaerobic infection, iv) Rheumatic fever. °) All are drug induced conditions, except : i) Parkinsonism. if) Peptic ulcer, iii) Infection, iv) Diabetes Mellitus. d) Which one is gaseous general anaesthetic : i) Halothane, if) Nitrous oxide, fii) Ether, iv) Enflurane, ©) Beta lactam ring is present in all, except : ) Cephalexin, if) Sulbactam, iii) Imipenem, iv) Vanocomyein,1 I/ 3, % y . Write short notes on (any five) : 2 {= a oi f The West Bengal University of Health Sciences BDS 2nd Professional Examination, 2013 Subject: General and Dental Pharmacology and Therapeutics ‘Time: 3 Hours Full Marks: 70 Use separate ansiver script for each group Grouped a) Enumerate local anaesthetic drugs. Describe mechanism of action of lignocaine. Why Adrenaline is given along with lignocaine? = or b) Name two general anaesthetics and two local anaesthetic drugs, Describe the mechanism of action and adverse effect of most commonly used local anaesthetic in dentistry. 46 5x4 a) Oral anticoagulant. b) Lincomyein. ¢) Proton Pump Inhibitors. d) Beta blockers. ©) Adrenaline. f} Inhalational route of drug administration. Identify the most appropriate response out of the multiple choices = Sx a) Metronidazole is used in all cases except : i) Amoebiasis. ii) Anaerobic infection, iii) Malarial infection. iv) Gingivitis. b) Vitamin K is used as an antidote in : i) Insulin overdose. ii) Organo phosphorous poisoning. iii) Oral anticoagulant overdose. iv) Iron poisoning. ¢) Antihypertensive drug used by sublingual route : i) Captopril. ii) Nifedifine til) Atenolol, iv) Amlodipin. d) Drug choice in chemotherapy induced vomiting : i) Domperidone. ii) Promethazine. iii) Ondencetron. iv) Metoclopramide. ¢) Drug of choice in motion sickness : i) Metoclopramide. ii) Chlorpromazine, iii) Scopolamine. iv) Diphenhydramine. P.T.O.Group-B 4) Bn broad spectrum antibi Mention the mechanism of action, uses ang ding effect of any one of them, 242545 or b) Name few of the bacteriocidal antibiotics. Briefly describe the mechanism of Action. use and adverse effect of any bacteriocidal antibiotic. BK 5. Write short notes (any five) : a) Co-trimoxazole. b) Fluorides. c) Metronidazole. d) Morphin. ¢) Antiplague agents f) Azithromycin. 2) Mospfin. SWephicnase Sud 6. Identify the most appropriate response out of the multiple choices. ME. =o, Sxl a) The drugs are anti fungal except : i) Flucanazole. ii) Albendazole. iii) Ketoconazole. iv) Grisiofulvin. bd) The ester link local anaesthetic is : “3 }) Lidocaine. ii) Cocaine. iii) Bupivacine. iv) Dibucaine. ¢) Low dose aspirin is used as : i) Analgesic. ii) Anti-inflammatory. iii) Anti-pyretic. iv) Anti thrombotic. 4) Route of administration of adrenalin with local anaesthetic ‘) Intravenous. ii) Intramuscular. ii) Subcutaneous. iv) Sublingual. ©) Drug of choice in morphin overdose : 5) Pethidine, ii) Naloxone. iy Vitamin K. iv) Atropin.L 2 3. The West Bengal University of Health Sciences BDS 2nd Professional (Supplementary) Examination, 2013 Subject: General and Dental Pharmacology and Therapeutics Time: 3 Hours. Full Mares: 70 Use separate answer script for each group Group-A. 8) Define Pharinacokinetic. Discuss the factors which ean modify drug absorption. 248 or 'b) What is first poss metabolism? Name four drugs which undergo high first pass metabolism. What are the clinical significances of first pass metabolism’? How we can avoid first pass metabolism? 2o2ede2 Write short notes on (any: five) : 3x4 8) Heparin, b) Azithromycin ©) Omeprazole, 4) Dapsone. ®) Zidovudine. Insulin, 8) Penicillin. Identify the most appropriate response out of the multiple choices : ~ Sx 8) Allare oral hypoglycaemic agent except i) Glibencamide, il) Metformin. iii) Glimepride. iv) Insulin. b) Morphine is used in all cases except + i) Fracture femur. ii) Head injury: iii) Cancer pain iv) Myocardial infarction. ¢) Aspirin should not be given in: i) Myocardial infarction. ii) Toothache. iii) Dengue fever. iv) Headache. d) Drug of choice Malignant malaria: i) Artesunate. ii) Chloroquine. lil) Primaquine, iv) Tetracycline. ¢) Protamine sulphate used as an antidotge in : i) Aspirin poisoning. ii) Morphine poisoning. ili) Oral anticoagulant poisoning. iv) Heparin overdose, P70. y b ss #2 aDw Group-B 2 chanism of action, dose ,, Describe the mec . # Fine antitubercullar drugs. sm 4a) Brvimerate the 1” Tine * adverse effect of any one of them, or anaesthetics drugs. Describe the mechanism b) Name two local anaesthetics and two general tistry. faction and adverse effect of most commonly used local anaesthetics in dent 2434342 $. Write short motes (aay five): +E4 a) Atropine. b) Fluorides. c) Metronidazole. @) Albendazole. ©) Aspirin. £) Metformin. 8) Fluconazole, © Wentify the mst appropriate response out of the multiple choice ; ae Sxl 8) Ciprofloxacin act by inhibiting ; 3) Cell all synihesis ii) Protein synthesis, # ¢g. iii) DNA gyrase, iv) mRNA synthesis. \ ‘ 4, L . b) Betab) x: : lockers are contraindicated in “S “ DH , ‘ pemtension i) Angina iii Diabetes mellitus, iv) Hyperth; 3 Low dose aspirin is used as : _ i) Analgesic. ii) Anti-inflammay iil) Anti-pyretic, iv) Anistroogg ic, a) . ee route Of administration OF insulin : , ItraVehous, ii) Intramuseiitar, iii) Subcutaneous ‘Ow molecular Weight heparin iaa) b) °°) dj ° The West Bengal University of Health Sciences BDS 2nd Professional (February Batch) Examination, 2012 Subject: General and Dental Pharmacology and Therapeutics Time: 3 Hours Full Marks: 70 Use separate answer script for each group Group-A . Answer any one of the following : 8) Define pharmacokinetics. What are the different pharmacokinetics processes? What are the different biotransformation reactions? What is half life of a drug? Mention the factors that may affect the half life, 14242414 b) Enumerate anticoagulants, Mention the mechanism of action, therapeutic uses and adverse effects of oral anticoagulants, 3434242 . Write short notes on (any five) = 5x4 a) DOTS. b) Bisphosphonates. ) Obtundants, 4) Tolerance. ¢) Metronidazole, f) Antiplaque agents. g) Antistaphylococeal penicillins. . Identify the mast appropriate response out of the multiple choices : Sxl The route of administration most likely to subject a drug to first-pass effect, is : i) Intravenous. ii) Oral. iii) Sublingual. iv) Inhalational, ‘Which of the following drugs is used to treat diabetic ketoacidosis : i) Glipizide. ii) Metformin. iii) Regular insulin, —_ iv) Glucagon. ‘The local anaesthetic agent most commonly used in dentalprocedures is : i) Procaine. ii) Lignocaine. iii) Bupivacaine. iv) Marcaine. All of the following are examples of neurotransmitters except : i) Epinephrine. ii) Ephedrine, iii) Aeetycholine. iv) Dopamine, ‘The drug of choice for the treatment of anaphylactic shock is : i) Dopamine. ii) Norepinephrine. iii) Hydrocortisone. iv) Epinephrine. P.T.O.B Group" ¢ the following * the mode of action, uses and adverse offs, ‘answer any ome OF _— . ‘ antibiotics: Mention 3424342 5. = jn ae ws foe preven OF ATIC Ni ifferent class, » wo non ve es of pain if detail practice. Deseribe wae - sx4 x Write short notes Om (any five) © a a) Domperidone. b) Dentrifice. ) Cotrimoxazole, d) on — ) Clotrimazole, f ug induced gingival reactions. g) Oral morphine- sc mont pri exo oct ma NOS sxl a) ‘Trigerninal neuralgia may bo treated with i) Morphine. i) Carbamazepine. ii) Naproxen. jy) Alprazolam. by “The rationale for combined use of adrenaline and 1 loca! anaesthetic, in dental procedures, include all the following, except : i) Prolonged local anaesthetic effect. ii) Less bleeding in surgical field. iii) Risk of anaphylaxis with the Jocal anaesthetic eliminated. iv) Systemic effects are less. ‘All the following about aspirin, are true except : i) It is a prostaglandin receptor antagonist, ii) It causes analgesia. iii) Long term use can cause nephropathy. iv) ‘At low dose it has antithrombotic action. ¢) 4) Which one of the following drugs is an antibiotic? {) Offoxacin, i) Meropenem. ii) Trimethoprim. iv) Metronidazole. ©) Which ofthe following vitamins in large doses is teratogenic? i) VitminD. if) Vitamin B6, ii) Vitamin A. iv) Vitamin C. alg = v/ ¥% 4, The West Bengal University of Health Sciences 28 4A BDS 2nd Professional Examination, 2012 J /f ‘Subject: General and Dental Pharmacology and Therapeuties ‘Time: 3 Hours Pull Marks: 70 Use separate answer seript for each group Group-A _ Answer any one of the following ; a) Enumerate the drugs acting on renin angiotensin system, Mention their clinical uses. 3+5 ~. b) Enumerate diuretics. Mention the mechanism of action of high ceiling diuretics. StS 2. Write short notes on (any five) : Sx4 a) Bioavailability. b) Anticoagulants, ¢) Local anaesthetics. 4) Antianginal drug. ¢) Purgatives. f) HAART. g) Drugs used in anaerobic infection. 3. Identify the most appropriate response out of the multiple choices : $x1 a) The drug is not a proton pump inhibitor : i) Omeprazole. ii) Pantoprazole, iii) Tinidazole. iv) Rabeprazole. b) Insulin is administered by : i) Oral route. ii) Subcutancous route. iii) Intramuscular route. iv) Intradermal route, s) Omnidazole is not used i) Antiamoebic drug. fi) Combination after dental extraction. iii) Anthelmintic. iv) Drug for gingivitis. d) Piracetam is used in i) Cerebral disease, ii) Gastro intestinal disease. ili) Cardiac disease, iv) Renal disease, . ¢) Adrenaline is combined with lignocaine : i) To increase the duration of action. {i) To decrease the duration of action. iii) To increase bioavailability, iv) To decrease the onset of action, P.T.O.Group-B 3 i anaesthesia in relation to Dental operation with used in general 4. a) Mention the drugs . advantages and disadvantages. & or the drugs used in the treatment of Peptic ulcer. Mention the mechanism of action ) Enumerate the 64 of omeprazole. Sx4 5. Write short notes on (any five) : / a) Antiseptics. b) Analgesics. ©) Anticaries agents. @) Otal contraceptives. €) Anti platelet drug f) Anti amoebics, 2) Low molecular weight heparin. 6. Identify the most appropriate answer : 5x1 2) Giardiasis is treated by < i) Norfloxacillin. ii) Metronidazole, ii) Ampicillin. iv) Amoxicillin. b) Low dose aspirin is used as ; 1) Analgesic. i) Antipyretic, ii) Anti inflammatory. iv) Antiplatelet. ©) Its not an anti hypertensive drug : i) Metoproiol fi) Losartan. 4) The drug is a diuretic ; ') ‘Clswpride. i) Amiloride. iil) Mosapride. iv) Albendazole, ‘Which one is used in drug induced vomiting : §) Metoclopramide. {i} Domperidone. iii). Hyoseine. iil) Amtodipine. iv); Wartact °) iv) Ondansetron,ra wen Bengat University of Health Sciences = an Slonal (Supplementary) Examination, 201 2 Swbjectt General and Dental Prarmavology and Therapewttes f er) Wlours Full Marks: 70 Use separate aniwer verlpt foreach group Croup. nswer any wre of the following ; ree Hy) Envimerace onnitiypeitensive drugs. Mention mechanism af action of B receptor on sHanisth as antihypsttensives, 45 My) Ervuinerats the drugs used In Bronchial asthma. Mention advantages of inhatational cure of, adrninisiation in the weatment of bronchial asthma a ‘ 4 Write short nutes an (any five) > a5 ‘a)_Non Ste:vidal anti inflammatory drugs. ) ‘Help life of drugs =e ©) Topical snsesthetics. 4) Drage used In aitterear typ OF I RETEH, Pe) Adverse’eifects of local anaesthetics. ff) Congutants. 'g) Metronidazole. , Y ‘ int Identi fy the most appropriate response + ae: ~ a) Drug used in Dinhetic Ketaacidosis : 4), Glimeperide. i) Metformin.) Aeatbose. _» Which one of the following drug is used in the treatment of leprosy . | iv) Insulin, i) Rifampicin. i) Pyrazinamide, ii) Etharnbutol, ivy tsonicotinic acid hydrazide, <} Whieh one ofthe following is an antiplatelet drug : i) Warfarin Sodium. ii) Vitamin K. iil) Streptokinase, iv) Aspitin. { 4) Which one of the following is Hy receptor antagonist + + 4) Famotidine. it} Pantoprazole, V iii) Sucruline, .v) Carbenoxolone So:tium. | ©) Which on ofthe folloOwing is. 2d in chronic gout ' ) ie ‘ino, ii) Aspirin. il) Paracetame!, iy), Tramadol. PTO. : \ 2ie : ‘. ds. Mention uses ofcorticos:troids. i 5s 2) omemecae the itcent preparations of catieosee? : © ae $45 >) B:pamecrate the anchelenintie drags #th their exe: Z Sx4 Write stdoer noted ca (aay Ave) 3 Nifeet wash, B) Thromibohties: , © Diterent preparation: of lasulin, ) Drugs used in therorsic sts. SO Astpieptic drags, ) Antipyretic drugs. @ Deus uscd in misria Weatitly ‘he most approsriste response : Sah a ‘Tine deug which is not used inverting : ae 9 Ondansetron §) Domperidone. il) Metoclopeammde. iv) Pecetamal. bp Tine drug which is 2 Reroguinoloae - ) ABatromyci: 1) Levefiowacin. ili) Suifamethoxaznte iv) Cetotaxim ) The rug which is oc uned scaly: D heme. 3 Metformin, i) Giipizide, iv) Acarbose. ® Mannitol is used in Cerebral Oedema_ ii) Cirrhosis of liver HD Congestive Canine fitore iv) [Neghrotic syedrnene ©) Assariasis is not treated with - D Medendazole - i) Levemisote. ili) Athendazole iy Teese:he Wer Benga University of Menlth Selences BDS © id Professional Examination, 2044 abet. General ada Dental Pharmacaogy ait Maton #9 UNE pe cuie anawer meu fee peok greg Anwar aay for free tact prog . Greupa Atemiy meer oe Atami dhnge ant gab agouti daw are given by dil terenk (utes ef ack HRMHEFOM. ‘Gaatiing the vscs; wode of tion and adverse effects of any one. WED ed 3) Enutnerawe uplotetmtyeaion Mention the dliferant opie! receptors and thelr phyysiolog significance, Deakneshe wes and coatraladieaticns of morphine HAT inn why: (any fords: ie ) Adirenctine is com’stned with a local anaesthetic. abet The newer andibioemines are often preftered over the conventional ones. Ra 4 ete ae : sea *b) en weno anacaihelics. Meayion the mechanism of action, and adverse effects ofone: |. HA” _ 8) Cassi vevighsielerugents, Mention the ications, aiverse drug-drug nneractions and Salty «oe wfTong-term use of any one such drug, ae) | je Wl Unie = sag fmr) ; axs a) haves “ala weg heparin, b) Demrifices, —)_ Half life of drugs, fs a Doct “One. ) Amoxicillien, Hos , \t .Fon 4 q no UHS~64Ntei2Q) 4 2nd Professional BBS Examina lorty 2001! a GENERAL AND DENTAL PHARMACOLOGY AND THERAPEUTICS ¢ Time Allowedt 3 Hours Halt Maris 999 . t Use separuie answer scripts for each sroup. Attempe all questions. ‘ Group A - 1. Atepipt any one: ‘ What is bioavailability of drugs? ' Prolong the deaton cy cast — the factor’ that affecr Dioavaiisbility. Mention the sMrategies to Iedeanyo (b) Enumerate iG used in the 1 Brie Sarasa mn a re oo poisoning with thisanalpesic? 2+3+343=10 2/ Write brief notes on (eany five): . 4xSe20 (8) Oploid receptor antagonists: (b) Therapeutic index; (©) Mouthwasi; (4) Drug dependence; te) Tinidizole: «~~ () Fluorides; (a) Oastrie antacids. 3. Mentify the most appropriate response out of the multiple choices: (4) The opioid antagonist given orally totreat morphine polsoning, is BY nalorphine (ii) nalbuphine (iii) naloxone (Gv) naltrexone (®) Which one of the following is a pro-drug? ) dipiveferine (ii) lisinopril (ii) ipeetropium (ivr glycopyrrotate (o) Regarding arninoglycoside antibioti '¢s. all the following statements are Correct, except (i) they are bactericidal (ii) they are effective against gram negative bacteria Ati) they are well absorbed orally (jr) they are grotonie (4) Indicate in which of the following & pharmacokinetic mechanism is hot involved: (7) tolerance to morphine. (Hi) OCP contraception failure by rifampicin (ill) tolerance 10 sedati ve-hypnotie action of barbiturates (ly primaquine-industd haemolytic uniemia ia) Which one of the following is not a catectolamine? = oF (i) adrenaline (ii) dopamine (Ill) Isoprenaline (yy'bistomine IxSes.SN Group 0 HSUDE LH ane Chis 1 ‘ean be given orally. » lissity pemeatting Outline their mechenvem of ection, Bnumerate the penicillins thi 00 oe Baal What ts penicillin “ anaphyl the condition? ynnis and how would you treat « averse sfecn ol ahs toy Dag?” “Mrsity Local angesthetics. Mention the mechanism of action therupeutic uses and a Sede dw 10 Sav, . 4ude20 - HS me bi ies on (an\ fvek: . ‘wy, Mevodlapremide *h) Anuicanes agent we Frenziiam (@) Rifompren (a) Albendazole a Disclosing agents (p-Orug-induced haemorrhagic complications Identify the most appropriate response out of the multiple choles: ? (0) Ail the following drugs may cause xerostomia (dry mauth)except () diphenhydramine (8) dieyclomine il) wevimeline (iv) trihexyphenidy! (b) All the following gre used as dental restorative materials, except } (i) goldalloy 4A) titanium (UN) mercury (iv) silveramalgam (c) Regarding vitamin K, all the following information nite correct, except (i) afatsoluble viumin (ii) needed forthe synthesis of clotting factors . Uii) increases oral anticoagulant induced bleeding (iv) deficiency increases bleeding tendencies (4) All the following regarding rational fixed-dose combination products, are (rue, except (i) they produce synergisticeffect (ii) treatment compliance improved with their use (iil) efficacy of eitherdrogis reduced —_(iv) adverse reactions of either agent is reduced (¢) Which one of the fallawing drugs is not effective in candidiasis? (i) itraconazole — (li) nystatin (ili) griseofulvin (iv) arpphotericinBQ: 14300 B.D.S. 2nd Professional Examtwuition, August Bateh,2010 (New Regulation) Phorm [ alo Subjece: Genernl and Dental Pharmacology and ‘Therapeutles Time Allowed—3 Hours Pull Marks—70 Use seperate answer seripis for each group, Attempt wil questions. . Grou A s _1_ Senet allowing ony one): (2) -Bifumerste the drugs used in congestive heart fiilure management. How does digoxin benefit in. this condition? Mention the comunon adverse effects of digoxin. renege te tenant of eigen icy. ’ aeae242 6 Enumerate the routes of administration of drugs with suitable eximples, What are the ndvantages and lisnitations of the oral route? Give two examples special drug diver armor mentioning the conditions ‘where they are used. } Av eH24D PARR itso sy 4x5 H antidiabetic agents; ()) rug dependence; : First pass effect; CH) Antibiotic prophylaxis; ~~ (6) Fixed dose combination forsulations; (g) HAART. « AB Peaniicass we 3_Biind the correct response out of multiple choices in the following: , Ixs (0) All the following statements about insulin are ture, except _ Itean cauise hypoglycemia = fi) Human inslulin is derived from human pancreatic tissue (ili) It ix used in selected cases of type 2 diabetes mellitus: . (iv) Regular insulin is given intravenously in diabetic ketoacldosis pea of the following agents have beta adrenergic property, oxcept (i) Isoprenaline (fi) Dopamine (iii) Alphamethyldopa (iv) Phenyle; The drug of choice in anaphylectic shock is (i) Ne i (i) Dopamine (iii) Ac (iv) Dexamethasone the ‘statements regarding biotrensformation are trus, except () Nisa: acodynamic process (il) It facilitates renal excretion of drugs: (iil) It invotves non-syrithetie and synthetic chemical rexctions (iv) It sometimes may be responsible for adverse drug-drug Interaction Please Turn Ove