R407A

A-Gas (U.S. Headquarters)

Version No: 6.1 Issue Date: 03/08/2021
Safety Data Sheet according to OSHA HazCom Standard (2012) requirements Print Date: 14/03/2022
[Link]

SECTION 1 Identification

Product Identifier
Product name R407A
Chemical Name Not Applicable

Synonyms Not Available

Proper shipping name Refrigerant gas R 407A

Chemical formula Not Applicable

Other means of identification Not Available

Recommended use of the chemical and restrictions on use

Relevant identified uses Refrigerant.

Name, address, and telephone number of the chemical manufacturer, importer, or other responsible party
Registered company name A-Gas (U.S. Headquarters)

Address 1100 Haskins Rd. Bowling Green, OH 43402 United States

Telephone 14198678990

Fax 1-419-867-3279

Website [Link]/us
Email [Link]@[Link]

Emergency phone number

Association / Organisation PERS CHEMWATCH EMERGENCY RESPONSE
Emergency telephone numbers 1-800-633-8253 +1 855-237-5573

Other emergency telephone

International 1-801-629-0667 +61 2 9186 1132
numbers

Once connected and if the message is not in your prefered language then please dial 01

Una vez conectado y si el mensaje no está en su idioma preferido, por favor marque 02

SECTION 2 Hazard(s) identification

Classification of the substance or mixture

NFPA 704 diamond

Note: The hazard category numbers found in GHS classification in section 2

of this SDSs are NOT to be used to fill in the NFPA 704 diamond. Blue =
Health Red = Fire Yellow = Reactivity White = Special (Oxidizer or water
reactive substances)

Classification Gases Under Pressure (Liquefied Gas)

Label elements

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R407A

Hazard pictogram(s)

Signal word Warning

Hazard statement(s)
H280 Contains gas under pressure; may explode if heated.

Hazard(s) not otherwise classified

Not Applicable

Precautionary statement(s) Prevention

Not Applicable

Precautionary statement(s) Response

Not Applicable

Precautionary statement(s) Storage

P410+P403 Protect from sunlight. Store in a well-ventilated place.

Precautionary statement(s) Disposal

Not Applicable

SECTION 3 Composition / information on ingredients

Substances
See section below for composition of Mixtures

Mixtures
CAS No %[weight] Name
811-97-2 36-44 R-134A
354-33-6 36-44 R125
75-10-5 16-24 R32

SECTION 4 First-aid measures

Description of first aid measures

If product comes in contact with eyes remove the patient from gas source or contaminated area.
Take the patient to the nearest eye wash, shower or other source of clean water.
Open the eyelid(s) wide to allow the material to evaporate.
Gently rinse the affected eye(s) with clean, cool water for at least 15 minutes. Have the patient lie or sit down and tilt the head back.
Hold the eyelid(s) open and pour water slowly over the eyeball(s) at the inner corners, letting the water run out of the outer corners.
The patient may be in great pain and wish to keep the eyes closed. It is important that the material is rinsed from the eyes to prevent
further damage.
Ensure that the patient looks up, and side to side as the eye is rinsed in order to better reach all parts of the eye(s)
Eye Contact
Transport to hospital or doctor.
Even when no pain persists and vision is good, a doctor should examine the eye as delayed damage may occur.
If the patient cannot tolerate light, protect the eyes with a clean, loosely tied bandage.
Ensure verbal communication and physical contact with the patient.
DO NOT allow the patient to rub the eyes
DO NOT allow the patient to tightly shut the eyes
DO NOT introduce oil or ointment into the eye(s) without medical advice
DO NOT use hot or tepid water.

If skin contact occurs:

Immediately remove all contaminated clothing, including footwear.
Flush skin and hair with running water (and soap if available).
Skin Contact Seek medical attention in event of irritation.
In case of cold burns (frost-bite):
Move casualty into warmth before thawing the affected part; if feet are affected carry if possible
Bathe the affected area immediately in luke-warm water (not more than 35 deg C) for 10 to 15 minutes, immersing if possible and

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R407A

without rubbing
DO NOT apply hot water or radiant heat.
Apply a clean, dry, light dressing of "fluffed-up" dry gauze bandage
If a limb is involved, raise and support this to reduce swelling
If an adult is involved and where intense pain occurs provide pain killers such as paracetomol
Transport to hospital, or doctor
Subsequent blackening of the exposed tissue indicates potential of necrosis, which may require amputation.
Following exposure to gas, remove the patient from the gas source or contaminated area.
NOTE: Personal Protective Equipment (PPE), including positive pressure self-contained breathing apparatus may be required to assure
the safety of the rescuer.
Prostheses such as false teeth, which may block the airway, should be removed, where possible, prior to initiating first aid procedures.
If the patient is not breathing spontaneously, administer rescue breathing.
If the patient does not have a pulse, administer CPR.
Inhalation If medical oxygen and appropriately trained personnel are available, administer 100% oxygen.
Summon an emergency ambulance. If an ambulance is not available, contact a physician, hospital, or Poison Control Centre for further
instruction.
Keep the patient warm, comfortable and at rest while awaiting medical care.
MONITOR THE BREATHING AND PULSE, CONTINUOUSLY.
Administer rescue breathing (preferably with a demand-valve resuscitator, bag-valve mask-device, or pocket mask as trained) or CPR if
necessary.
Ingestion Not considered a normal route of entry.

Most important symptoms and effects, both acute and delayed

See Section 11

Indication of any immediate medical attention and special treatment needed

for intoxication due to Freons/ Halons;
A: Emergency and Supportive Measures
Maintain an open airway and assist ventilation if necessary
Treat coma and arrhythmias if they occur. Avoid (adrenaline) epinephrine or other sympathomimetic amines that may precipitate ventricular arrhythmias. Tachyarrhythmias
caused by increased myocardial sensitisation may be treated with propranolol, 1-2 mg IV or esmolol 25-100 microgm/kg/min IV.
Monitor the ECG for 4-6 hours
B: Specific drugs and antidotes:
There is no specific antidote
C: Decontamination
Inhalation; remove victim from exposure, and give supplemental oxygen if available.
Ingestion; (a) Prehospital: Administer activated charcoal, if available. DO NOT induce vomiting because of rapid absorption and the risk of abrupt onset CNS depression. (b)
Hospital: Administer activated charcoal, although the efficacy of charcoal is unknown. Perform gastric lavage only if the ingestion was very large and recent (less than 30
minutes)
D: Enhanced elimination:
There is no documented efficacy for diuresis, haemodialysis, haemoperfusion, or repeat-dose charcoal.
POISONING and DRUG OVERDOSE, Californian Poison Control System Ed. Kent R Olson; 3rd Edition
Do not administer sympathomimetic drugs unless absolutely necessary as material may increase myocardial irritability.
No specific antidote.
Because rapid absorption may occur through lungs if aspirated and cause systematic effects, the decision of whether to induce vomiting or not should be made by an
attending physician.
If lavage is performed, suggest endotracheal and/or esophageal control.
Danger from lung aspiration must be weighed against toxicity when considering emptying the stomach.
Treatment based on judgment of the physician in response to reactions of the patient
For frost-bite caused by liquefied petroleum gas:
If part has not thawed, place in warm water bath (41-46 C) for 15-20 minutes, until the skin turns pink or red.
Analgesia may be necessary while thawing.
If there has been a massive exposure, the general body temperature must be depressed, and the patient must be immediately rewarmed by whole-body immersion, in a
bath at the above temperature.
Shock may occur during rewarming.
Administer tetanus toxoid booster after hospitalization.
Prophylactic antibiotics may be useful.
The patient may require anticoagulants and oxygen.
[Shell Australia 22/12/87]
For gas exposures:
--------------------------------------------------------------
BASIC TREATMENT
--------------------------------------------------------------
Establish a patent airway with suction where necessary.
Watch for signs of respiratory insufficiency and assist ventilation as necessary.
Administer oxygen by non-rebreather mask at 10 to 15 l/min.
Monitor and treat, where necessary, for pulmonary oedema .
Monitor and treat, where necessary, for shock.

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R407A

Anticipate seizures.
--------------------------------------------------------------
ADVANCED TREATMENT
--------------------------------------------------------------
Consider orotracheal or nasotracheal intubation for airway control in unconscious patient or where respiratory arrest has occurred.
Positive-pressure ventilation using a bag-valve mask might be of use.
Monitor and treat, where necessary, for arrhythmias.
Start an IV D5W TKO. If signs of hypovolaemia are present use lactated Ringers solution. Fluid overload might create complications.
Drug therapy should be considered for pulmonary oedema.
Hypotension with signs of hypovolaemia requires the cautious administration of fluids. Fluid overload might create complications.
Treat seizures with diazepam.
Proparacaine hydrochloride should be used to assist eye irrigation.
BRONSTEIN, A.C. and CURRANCE, P.L.
EMERGENCY CARE FOR HAZARDOUS MATERIALS EXPOSURE: 2nd Ed. 1994

SECTION 5 Fire-fighting measures

Extinguishing media
SMALL FIRE: Use extinguishing agent suitable for type of surrounding fire.
LARGE FIRE: Cool cylinder.
DO NOT direct water at source of leak or venting safety devices as icing may occur.

Special hazards arising from the substrate or mixture

Fire Incompatibility Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine bleaches, pool chlorine etc. as ignition may result

Special protective equipment and precautions for fire-fighters

--------------------------------------------------------------
GENERAL
--------------------------------------------------------------
Fire Fighting Alert Fire Brigade and tell them location and nature of hazard.
Wear breathing apparatus and protective gloves.
Fight fire from a safe distance, with adequate cover.
Use water delivered as a fine spray to control fire and cool adjacent area.
Containers may explode when heated - Ruptured cylinders may rocket
Fire exposed containers may vent contents through pressure relief devices.
High concentrations of gas may cause asphyxiation without warning.
May decompose explosively when heated or involved in fire.
Contact with gas may cause burns, severe injury and/ or frostbite.
Fire/Explosion Hazard Decomposition may produce toxic fumes of:
carbon monoxide (CO)
carbon dioxide (CO2)
hydrogen fluoride
other pyrolysis products typical of burning organic material.
Contains low boiling substance: Closed containers may rupture due to pressure buildup under fire conditions.

SECTION 6 Accidental release measures

Personal precautions, protective equipment and emergency procedures

See section 8

Environmental precautions
See section 12

Methods and material for containment and cleaning up

Avoid breathing vapour and any contact with liquid or gas. Protective equipment including respirator should be used.
Minor Spills DO NOT enter confined spaces where gas may have accumulated.
Increase ventilation.

Clear area of all unprotected personnel and move upwind.

Alert Emergency Authority and advise them of the location and nature of hazard.
Major Spills
Wear breathing apparatus and protective gloves.
Prevent by any means available, spillage from entering drains and water-courses.

Personal Protective Equipment advice is contained in Section 8 of the SDS.

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R407A

SECTION 7 Handling and storage

Precautions for safe handling

· Consider use in closed pressurised systems, fitted with temperature, pressure and safety relief valves which are vented for
safe dispersal. Use only properly specified equipment which is suitable for this product, its supply pressure and temperature
· The tubing network design connecting gas cylinders to the delivery system should include appropriate pressure indicators
and vacuum or suction lines.
Safe handling
· Fully-welded types of pressure gauges, where the bourdon tube sensing element is welded to the gauge body, are
recommended.
· Before connecting gas cylinders, ensure manifold is mechanically secure and does not containing another gas.
DO NOT transfer gas from one cylinder to another.

· Do NOT store halogenated aliphatics in areas containing alkali or alkaline earth metals such as powdered aluminum, zinc, or
beryllium
Cylinders should be stored in a purpose-built compound with good ventilation, preferably in the open.
Other information
Such compounds should be sited and built in accordance with statutory requirements.
The storage compound should be kept clear and access restricted to authorised personnel only.
Cylinders stored in the open should be protected against rust and extremes of weather.

Conditions for safe storage, including any incompatibilities

DO NOT use aluminium or galvanised containers
Cylinder:
Ensure the use of equipment rated for cylinder pressure.
Suitable container
Ensure the use of compatible materials of construction.
Valve protection cap to be in place until cylinder is secured, connected.
Cylinder must be properly secured either in use or in storage.
Storage incompatibility metals

SECTION 8 Exposure controls / personal protection

Control parameters

Occupational Exposure Limits (OEL)

INGREDIENT DATA
Not Available

Emergency Limits

Ingredient TEEL-1 TEEL-2 TEEL-3

R-134A Not Available Not Available Not Available

R32 3,000 ppm 6,500 ppm 39,000 ppm

Ingredient Original IDLH Revised IDLH

R-134A Not Available Not Available

R125 Not Available Not Available

R32 Not Available Not Available

MATERIAL DATA

Exposure controls
Engineering controls are used to remove a hazard or place a barrier between the worker and the hazard. Well-designed engineering controls
can be highly effective in protecting workers and will typically be independent of worker interactions to provide this high level of protection.
Appropriate engineering The basic types of engineering controls are:
controls Process controls which involve changing the way a job activity or process is done to reduce the risk.
Enclosure and/or isolation of emission source which keeps a selected hazard "physically" away from the worker and ventilation that
strategically "adds" and "removes" air in the work environment.

Personal protection

Chemical goggles.
Full face shield may be required for supplementary but never for primary protection of eyes.
Eye and face protection
Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. A written policy document,
describing the wearing of lenses or restrictions on use, should be created for each workplace or task.

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R407A

Skin protection See Hand protection below

Butyl rubber gloves
· Butyl rubber gloves should be used when handling halogenated aliphatics .
· Nitrile, PVC-coated nitrile, and PVC protective equipment are not recommended
Hands/feet protection When handling sealed and suitably insulated cylinders wear cloth or leather gloves.
Insulated gloves:
NOTE: Insulated gloves should be loose fitting so that may be removed quickly if liquid is spilled upon them. Insulated gloves are not made to
permit hands to be placed in the liquid; they provide only short-term protection from accidental contact with the liquid.

Body protection See Other protection below

· Halogen-selective detectors use a specialized sensor that allows the monitor to detect compounds containing fluorine,
chlorine, bromine, and iodine with-out interference from other [Link] detectors are typically easy to use, feature higher
sensitivity than the nonselective detectors (detection limits are typically <5 ppm when used as an area monitor and <1.4 gm/yr
[<0.05 oz/yr] when used as a leak pinpointer).
· Compound-Specific Detectors are typically capable of detecting the presence of a single compound without interference
Other protection
from other compounds.
Protective overalls, closely fitted at neck and wrist.
Eye-wash unit.
Ensure availability of lifeline in confined spaces.
Staff should be trained in all aspects of rescue work.

Respiratory protection
Type AX Filter of sufficient capacity. (AS/NZS 1716 & 1715, EN 143:2000 & 149:2001, ANSI Z88 or national equivalent)

Selection of the Class and Type of respirator will depend upon the level of breathing zone contaminant and the chemical nature of the contaminant. Protection Factors (defined
as the ratio of contaminant outside and inside the mask) may also be important.

Required minimum protection factor Maximum gas/vapour concentration present in air p.p.m. (by volume) Half-face Respirator Full-Face Respirator
up to 10 1000 AX-AUS / Class1 -
up to 50 1000 - AX-AUS / Class 1

up to 50 5000 Airline * -
up to 100 5000 - AX-2
up to 100 10000 - AX-3

100+ Airline**

* - Continuous Flow ** - Continuous-flow or positive pressure demand

A(All classes) = Organic vapours, B AUS or B1 = Acid gasses, B2 = Acid gas or hydrogen cyanide(HCN), B3 = Acid gas or hydrogen cyanide(HCN), E = Sulfur dioxide(SO2), G =
Agricultural chemicals, K = Ammonia(NH3), Hg = Mercury, NO = Oxides of nitrogen, MB = Methyl bromide, AX = Low boiling point organic compounds(below 65 degC)

Cartridge respirators should never be used for emergency ingress or in areas of unknown vapour concentrations or oxygen content.
The wearer must be warned to leave the contaminated area immediately on detecting any odours through the respirator. The odour may indicate that the mask is not
functioning properly, that the vapour concentration is too high, or that the mask is not properly fitted. Because of these limitations, only restricted use of cartridge
respirators is considered appropriate.
Cartridge performance is affected by humidity. Cartridges should be changed after 2 hr of continuous use unless it is determined that the humidity is less than 75%, in which
case, cartridges can be used for 4 hr. Used cartridges should be discarded daily, regardless of the length of time used
Positive pressure, full face, air-supplied breathing apparatus should be used for work in enclosed spaces if a leak is suspected or the primary containment is to be opened
(e.g. for a cylinder change)
Air-supplied breathing apparatus is required where release of gas from primary containment is either suspected or demonstrated.
Selection of the Class and Type of respirator will depend upon the level of breathing zone contaminant and the chemical nature of the contaminant. Protection Factors (defined
as the ratio of contaminant outside and inside the mask) may also be important.

Required minimum protection factor Maximum gas/vapour concentration present in air p.p.m. (by volume) Half-face Respirator Full-Face Respirator

up to 10 1000 AX-AUS / Class 1 -

up to 50 1000 - AX-AUS / Class 1

up to 50 5000 Airline * -

up to 100 5000 - AX-2

up to 100 10000 - AX-3

100+ - Airline**

** - Continuous-flow or positive pressure demand.

A(All classes) = Organic vapours, B AUS or B1 = Acid gases, B2 = Acid gas or hydrogen cyanide(HCN), B3 = Acid gas or hydrogen cyanide(HCN), E = Sulfur dioxide(SO2), G =
Agricultural chemicals, K = Ammonia(NH3), Hg = Mercury, NO = Oxides of nitrogen, MB = Methyl bromide, AX = Low boiling point organic compounds(below 65 deg C)

SECTION 9 Physical and chemical properties

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R407A

Information on basic physical and chemical properties

Appearance Colourless liquefied gas with a slight ether odour.

Physical state Liquified Gas Relative density (Water = 1) 1.15 @25C

Partition coefficient n-octanol
Odour Not Available Not Available
/ water

Odour threshold Not Available Auto-ignition temperature (°C) Not Available

pH (as supplied) Not Available Decomposition temperature Not Available

Melting point / freezing point

Not Available Viscosity (cSt) Not Available
(°C)
Initial boiling point and boiling
-45 Molecular weight (g/mol) Not Applicable
range (°C)

Flash point (°C) Not Available Taste Not Available

Evaporation rate Not Available Explosive properties Not Available

Flammability Not Available Oxidising properties Not Available

Surface Tension (dyn/cm or

Upper Explosive Limit (%) Not Available Not Available
mN/m)

Lower Explosive Limit (%) Not Available Volatile Component (%vol) Not Available
Vapour pressure (kPa) 1253 @25C Gas group Not Available
pH as a solution (Not
Solubility in water Not Available Not Available
Available%)
Vapour density (Air = 1) 3.2 VOC g/L Not Available

SECTION 10 Stability and reactivity

Reactivity See section 7

Unstable in the presence of incompatible materials.
Chemical stability Product is considered stable.
Hazardous polymerisation will not occur.

Possibility of hazardous
See section 7
reactions

Conditions to avoid See section 7

Incompatible materials See section 7
Hazardous decomposition
See section 5
products

SECTION 11 Toxicological information

Information on toxicological effects

Inhalation of vapours may cause drowsiness and dizziness. This may be accompanied by narcosis, reduced alertness, loss of reflexes, lack of
coordination and vertigo.
Inhalation of vapours or aerosols (mists, fumes), generated by the material during the course of normal handling, may be damaging to the
health of the individual.
Limited evidence or practical experience suggests that the material may produce irritation of the respiratory system, in a significant number
Inhaled
of individuals, following inhalation. In contrast to most organs, the lung is able to respond to a chemical insult by first removing or
neutralising the irritant and then repairing the damage. The repair process, which initially evolved to protect mammalian lungs from foreign
matter and antigens, may however, produce further lung damage resulting in the impairment of gas exchange, the primary function of the
lungs. Respiratory tract irritation often results in an inflammatory response involving the recruitment and activation of many cell types,
mainly derived from the vascular system.
Ingestion Considered an unlikely route of entry in commercial/industrial environments

Limited evidence exists, or practical experience predicts, that the material either produces inflammation of the skin in a substantial number
of individuals following direct contact, and/or produces significant inflammation when applied to the healthy intact skin of animals, for up to
four hours, such inflammation being present twenty-four hours or more after the end of the exposure period. Skin irritation may also be
present after prolonged or repeated exposure; this may result in a form of contact dermatitis (nonallergic). The dermatitis is often
Skin Contact characterised by skin redness (erythema) and swelling (oedema) which may progress to blistering (vesiculation), scaling and thickening of the
epidermis. At the microscopic level there may be intercellular oedema of the spongy layer of the skin (spongiosis) and intracellular oedema
of the epidermis.
Open cuts, abraded or irritated skin should not be exposed to this material
Entry into the blood-stream through, for example, cuts, abrasions, puncture wounds or lesions, may produce systemic injury with harmful
effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.

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R407A

Vapourising liquid causes rapid cooling and contact may cause cold burns, frostbite, even through normal gloves. Frozen skin tissues are
painless and appear waxy and yellow. Signs and symptoms of frost-bite may include "pins and needles", paleness followed by numbness, a
hardening an stiffening of the skin, a progression of colour changes in the affected area, (first white, then mottled and blue and eventually
black; on recovery, red, hot, painful and blistered).
Limited evidence suggests that repeated exposure may cause skin cracking, flaking or drying following normal handling and use.
Direct contact with the eye may not cause irritation because of the extreme volatility of the gas; however concentrated atmospheres may
Eye
produce irritation after brief exposures..

Limited evidence suggests that repeated or long-term occupational exposure may produce cumulative health effects involving organs or
Chronic
biochemical systems.

TOXICITY IRRITATION
R407A
Not Available Not Available

TOXICITY IRRITATION
R-134A
Inhalation(Rat) LC50; 359453.102 ppm4h[2] Not Available

TOXICITY IRRITATION
R125
Inhalation(Rat) LC50; >709000 ppm4h[2] Not Available

TOXICITY IRRITATION

R32 Inhalation(Rat) LC50; >760000 ppm4h[2] Not Available

Oral (Mouse) LD50; 1810 mg/kg[2]

Legend: 1. Value obtained from Europe ECHA Registered Substances - Acute toxicity 2.* Value obtained from manufacturer's SDS. Unless otherwise
specified data extracted from RTECS - Register of Toxic Effect of chemical Substances

* with added oxygen - ZhongHao New Chemical Materials MSDS Excessive concentration can have a narcotic effect; inhalation of high
concentrations of decomposition products can cause lung oedema.
Disinfection by products (DBPs) re formed when disinfectants such as chlorine, chloramine, and ozone react with organic and inorganic
matter in water. The observations that some DBPs such as trihalomethanes (THMs), di-/trichloroacetic acids, and 3-chloro-
R-134A
4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) are carcinogenic in animal studies have raised public concern over the possible adverse
health effects of DBPs. To date, several hundred DBPs have been identified.
Numerous haloalkanes and haloalkenes have been tested for carcinogenic and mutagenic activities. n general, the genotoxic potential is
dependent on the nature, number, and position of halogen(s) and the molecular size of the compound.
R125 Cardiac sensitisation threshold limit >245400 mg/m3 Anaesthetic effects threshold limit 490800 mg/m3 * DuPont SDS

Acute Toxicity Carcinogenicity

Skin Irritation/Corrosion Reproductivity

Serious Eye Damage/Irritation STOT - Single Exposure

Respiratory or Skin
STOT - Repeated Exposure
sensitisation
Mutagenicity Aspiration Hazard

Legend: – Data either not available or does not fill the criteria for classification
– Data available to make classification

SECTION 12 Ecological information

Toxicity

Endpoint Test Duration (hr) Species Value Source

R407A Not Not Not
Not Available Not Available
Available Available Available

Endpoint Test Duration (hr) Species Value Source

NOEC(ECx) 72h Algae or other aquatic plants ~13.2mg/l 2

LC50 96h Fish 450mg/l 2

R-134A
EC50 72h Algae or other aquatic plants >114mg/l 2

EC50 48h Crustacea 980mg/L 5

EC50 96h Algae or other aquatic plants 142mg/l 2

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R407A

Endpoint Test Duration (hr) Species Value Source

LC50 96h Fish >81.8mg/l 2
EC50 72h Algae or other aquatic plants >114mg/l 2
R125
EC50 48h Crustacea >97.9mg/l 2

NOEC(ECx) 96h Fish 10mg/l 2

EC50 96h Algae or other aquatic plants 142mg/l 2

Endpoint Test Duration (hr) Species Value Source

NOEC(ECx) 96h Fish 10mg/l 2

LC50 96h Fish >81.8mg/l 2

R32
EC50 72h Algae or other aquatic plants >114mg/l 2

EC50 48h Crustacea >97.9mg/l 2

EC50 96h Algae or other aquatic plants 142mg/l 2

Legend: Extracted from 1. IUCLID Toxicity Data 2. Europe ECHA Registered Substances - Ecotoxicological Information - Aquatic Toxicity 4. US EPA,
Ecotox database - Aquatic Toxicity Data 5. ECETOC Aquatic Hazard Assessment Data 6. NITE (Japan) - Bioconcentration Data 7. METI (Japan) -
Bioconcentration Data 8. Vendor Data

DO NOT discharge into sewer or waterways.

Persistence and degradability

Ingredient Persistence: Water/Soil Persistence: Air

R-134A HIGH HIGH

R125 HIGH HIGH
R32 LOW LOW

Bioaccumulative potential
Ingredient Bioaccumulation

R-134A LOW (LogKOW = 1.68)

R125 LOW (LogKOW = 1.5472)
R32 LOW (LogKOW = 0.2)

Mobility in soil
Ingredient Mobility

R-134A LOW (KOC = 96.63)

R125 LOW (KOC = 154.4)

R32 LOW (KOC = 23.74)

SECTION 13 Disposal considerations

Waste treatment methods

Evaporate residue at an approved site.
Return empty containers to supplier. If containers are marked non-returnable establish means of disposal with manufacturer prior to
Product / Packaging disposal
purchase.
Ensure damaged or non-returnable cylinders are gas-free before disposal.

SECTION 14 Transport information

Labels Required

Marine Pollutant NO

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R407A

Land transport (DOT)

UN number 3338
UN proper shipping name Refrigerant gas R 407A

Class 2.2
Transport hazard class(es)
Subrisk Not Applicable

Packing group Not Applicable

Environmental hazard Not Applicable

Hazard Label 2.2

Special precautions for user
Special provisions T50

Air transport (ICAO-IATA / DGR)

UN number 3338
UN proper shipping name Refrigerant gas R 407A

ICAO/IATA Class 2.2

Transport hazard class(es) ICAO / IATA Subrisk Not Applicable
ERG Code 2L

Packing group Not Applicable

Environmental hazard Not Applicable

Special provisions Not Applicable

Cargo Only Packing Instructions 200

Cargo Only Maximum Qty / Pack 150 kg

Special precautions for user Passenger and Cargo Packing Instructions 200
Passenger and Cargo Maximum Qty / Pack 75 kg

Passenger and Cargo Limited Quantity Packing Instructions Forbidden

Passenger and Cargo Limited Maximum Qty / Pack Forbidden

Sea transport (IMDG-Code / GGVSee)

UN number 3338
UN proper shipping name REFRIGERANT GAS R 407A

IMDG Class 2.2

Transport hazard class(es)
IMDG Subrisk Not Applicable

Packing group Not Applicable

Environmental hazard Not Applicable

EMS Number F-C, S-V

Special precautions for user Special provisions Not Applicable

Limited Quantities 120 mL

Transport in bulk according to Annex II of MARPOL and the IBC code

Not Applicable

Transport in bulk in accordance with MARPOL Annex V and the IMSBC Code
Product name Group

R-134A Not Available

R125 Not Available

R32 Not Available

Transport in bulk in accordance with the ICG Code

Product name Ship Type

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R407A

Product name Ship Type

R-134A Not Available

R125 Not Available

R32 Not Available

SECTION 15 Regulatory information

Safety, health and environmental regulations / legislation specific for the substance or mixture

R-134A is found on the following regulatory lists

US AIHA Workplace Environmental Exposure Levels (WEELs) US Toxic Substances Control Act (TSCA) - Chemical Substance Inventory
US DOE Temporary Emergency Exposure Limits (TEELs) US Toxicology Excellence for Risk Assessment (TERA) Workplace Environmental
US EPA Integrated Risk Information System (IRIS) Exposure Levels (WEEL)
US TSCA Chemical Substance Inventory - Interim List of Active Substances

R125 is found on the following regulatory lists

US AIHA Workplace Environmental Exposure Levels (WEELs) US Toxicology Excellence for Risk Assessment (TERA) Workplace Environmental
US EPA Integrated Risk Information System (IRIS) Exposure Levels (WEEL)
US Toxic Substances Control Act (TSCA) - Chemical Substance Inventory US TSCA Chemical Substance Inventory - Interim List of Active Substances

R32 is found on the following regulatory lists

US AIHA Workplace Environmental Exposure Levels (WEELs) US Toxic Substances Control Act (TSCA) - Chemical Substance Inventory
US CWA (Clean Water Act) - Toxic Pollutants US Toxicology Excellence for Risk Assessment (TERA) Workplace Environmental
US DOE Temporary Emergency Exposure Limits (TEELs) Exposure Levels (WEEL)
US TSCA Chemical Substance Inventory - Interim List of Active Substances

Federal Regulations

Superfund Amendments and Reauthorization Act of 1986 (SARA)

Section 311/312 hazard categories

Flammable (Gases, Aerosols, Liquids, or Solids) No

Gas under pressure Yes

Explosive No
Self-heating No

Pyrophoric (Liquid or Solid) No

Pyrophoric Gas No
Corrosive to metal No

Oxidizer (Liquid, Solid or Gas) No

Organic Peroxide No

Self-reactive No
In contact with water emits flammable gas No

Combustible Dust No

Carcinogenicity No
Acute toxicity (any route of exposure) No

Reproductive toxicity No

Skin Corrosion or Irritation No

Respiratory or Skin Sensitization No

Serious eye damage or eye irritation No

Specific target organ toxicity (single or repeated exposure) No

Aspiration Hazard No

Germ cell mutagenicity No

Simple Asphyxiant No
Hazards Not Otherwise Classified No

US. EPA CERCLA Hazardous Substances and Reportable Quantities (40 CFR 302.4)
None Reported

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R407A

State Regulations

US. California Proposition 65

None Reported

National Inventory Status

National Inventory Status

Australia - AIIC / Australia

Yes
Non-Industrial Use

Canada - DSL Yes

Canada - NDSL No (R-134A; R125; R32)

China - IECSC No (R32)

Europe - EINEC / ELINCS / NLP Yes

Japan - ENCS Yes

Korea - KECI Yes

New Zealand - NZIoC Yes

Philippines - PICCS Yes
USA - TSCA Yes

Taiwan - TCSI Yes

Mexico - INSQ Yes
Vietnam - NCI Yes

Russia - FBEPH Yes

Yes = All CAS declared ingredients are on the inventory
Legend:
No = One or more of the CAS listed ingredients are not on the inventory. These ingredients may be exempt or will require registration.

SECTION 16 Other information

Revision Date 03/08/2021

Initial Date 12/10/2015

SDS Version Summary

Version Date of Update Sections Updated
5.1 01/11/2019 One-off system update. NOTE: This may or may not change the GHS classification

6.1 03/08/2021 Appearance, Classification, Ingredients, Physical Properties, Storage (storage incompatibility), Use

Other information
Classification of the preparation and its individual components has drawn on official and authoritative sources using available literature references.

The SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. Many factors determine whether the reported Hazards are Risks in the workplace
or other settings. Risks may be determined by reference to Exposures Scenarios. Scale of use, frequency of use and current or available engineering controls must be considered.

Definitions and abbreviations

PC－TWA: Permissible Concentration-Time Weighted Average
PC－STEL: Permissible Concentration-Short Term Exposure Limit
IARC: International Agency for Research on Cancer
ACGIH: American Conference of Governmental Industrial Hygienists
STEL: Short Term Exposure Limit
TEEL: Temporary Emergency Exposure Limit。
IDLH: Immediately Dangerous to Life or Health Concentrations
ES: Exposure Standard
OSF: Odour Safety Factor
NOAEL :No Observed Adverse Effect Level
LOAEL: Lowest Observed Adverse Effect Level
TLV: Threshold Limit Value
LOD: Limit Of Detection
OTV: Odour Threshold Value
BCF: BioConcentration Factors
BEI: Biological Exposure Index

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R407A

AIIC: Australian Inventory of Industrial Chemicals

DSL: Domestic Substances List
NDSL: Non-Domestic Substances List
IECSC: Inventory of Existing Chemical Substance in China
EINECS: European INventory of Existing Commercial chemical Substances
ELINCS: European List of Notified Chemical Substances
NLP: No-Longer Polymers
ENCS: Existing and New Chemical Substances Inventory
KECI: Korea Existing Chemicals Inventory
NZIoC: New Zealand Inventory of Chemicals
PICCS: Philippine Inventory of Chemicals and Chemical Substances
TSCA: Toxic Substances Control Act
TCSI: Taiwan Chemical Substance Inventory
INSQ: Inventario Nacional de Sustancias Químicas
NCI: National Chemical Inventory
FBEPH: Russian Register of Potentially Hazardous Chemical and Biological Substances

end of SDS