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Strength Duration Curve
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Strength Duration Curve
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Voltage 35 28 21 1.4 07 7 Strength Duration Curve + 2 x Rheobase ee Rheabace ve Volts) 0.0 02 04 06 08 70 1.2 Chronaxie (in ms) Duration * Strength duration curve is a graph between electrical stimuli of different intensities and recording the time needed by each stimulus to start the response * Purpose : To see the excitability of the tissue . To Check if a muscle Is innervated or denervated3 2 3 E a S 6 S 5 a Strength duration curve Utilization time (nerve) Utilization time (muscle) .Chronaxie of nerve ae of muscle 01 0.2 03 Duration of stimulus (Seconds) Rheobase ‘Rheobase is defined as the minimal current which when allowed to flow indefinitely will exeite a tissue. Chronaxie ‘shortest duration of stimulus requited to excite a tissue by a current strength equal to twice of Rheobase voltage. Chronaxie defines the excitability of the tissue longer chronaxie ~ Less Excitable —_ Utilization time |Itis the time taken by a stimulus of rheobasic strength to excite the nerve and produce a muscle contraction. Below this value, there will be no muscle contractionDenervated muscle Party denerated pletely denervated —// ei re, )@ ©Comparison of Excitability Slower less excitable fibres Chronaxie AMalignant Hyperthermia triggered by inhalation© Lactic acidosis Malignant Hyperthermia Late Clinical Signs of Malignant eae Generalized skeletal muscle rigidity © Ability to generate ATPis nearly exhausted [ Werectnenrweee [PSerrercene) Cyanosis © Low oxygen saturation © Skin appear to be purple or blue Dark urine © increased creatine kinase Temperature rise above 40°C Death
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