1016MSC - Module 1 - Lecture Notes
1016MSC - Module 1 - Lecture Notes
Skeletal System
MODULE 1
Skeletal System
Topic 1.1a:
Bones, tissues, development
Learning Objectives
Skeletal System
Overview
How is the Body Organised?
1. Chemical level 3. Cellular level
Atoms → molecules Atoms → molecules § Atoms Micro
§ Molecules
3. Tissue § Organelles
Similar cell types
§ Cellular level
§ Tissue level
§ Organ level Macro
§ Organ system level
4. Organ level § Organism level
Different tissues (i.e. blood vessel)
Skeletal System
Body Planes &
Sections
§ Using an anatomical reference is
important when describing body parts
Midsagittal Frontal/coronal Transverse
§ This reference point is termed the
“Anatomical Position”
Most frequently used are:
§ Sagittal - divides body into left/right
§ Frontal/Coronal - divides body into
anterior & posterior
§ Transverse - divides body into superior
and inferior
Skeletal System
Orientation
&
terminology
Superior
§ Superior/Inferior Dorsal
§ Ventral/Dorsal Medial
§ Medial/ Lateral
Lateral
Orientation
&
terminology Proximal
§ Proximal/Distal Distal
§ Superficial/ Deep
Superficial
Deep
Skeletal System
Body cavities
1. Ventral body cavity (more anterior &
larger)
Skeletal System
Skeleton
bones & cartilage
§ Human skeleton = contains cartilages and fibrous
membrane (replaced by bone)
§ Cartilage - maintains flexibility (hyaline, elastic,
fibrocartilage)
§ Bone is classified as = Connective tissue
§ Function of the skeleton is to provide:
§ Protection
§ Support
§ Anchorage
§ Mineral storage
§ Blood cell formation (or haemopoesis in bone
marrow)
§ Fat storage (energy) - yellow marrow
Skeletal System
Classification of bones
§ Human body has 206 Bones
§ Divided into 2 GROUPS
1. Axial (‘long axis’ – skull,
vertebral column, rib cage)
2. Appendicular (upper/lower &
girdles (shoulder/hip bones)
Bones are classified by their LOCATION
and SHAPE (this is important!)
§ Long (longer than they are wide)
§ Flat (thin, flattened)
§ Irregular (complicated shapes)
§ Short (roughly cubed) Name an example of each?
Skeletal System
Bone Markings 1
Where do you
belong?
2
§ Bone markings – a wealth of
information about the bone and its
3
attached muscles/ligaments
§ 3 categories
1. Projections
2. Surfaces (that form joints)
3. Depressions & Openings
Sectioned proximal
femur (thigh bone)
General Structure:
long bones
General structure:
shaft, bone ends & membranes
= strong bond
§ Endosteum (“within the bone”)
§ connective tissue covering internal
bone surfaces
§ lines canals and trabeculae
Microscopic Anatomy of Bone
Bone formation & remodelling
Skeletal development
§ Ossification and osteogenesis = bone
tissue formation (genesis = beginning)
§ In utero (in embryos)
§ formation of the bony skeleton
Learning Objectives
endochondral ossification
Osteoporosis
Skeletal System
Ossification
Formation of Bony Skeleton
Skeletal System
Endochondral ossification BIRTH
Lets examine the steps of long bone
formation.
Skeletal System
Intramembranous Ossification
1. Development of ossification centre (Stem cells migrate and
transform into osteoblasts )
2. Osteoid is secreted & calcifies (by osteoblasts) trapped
osteoblasts become osteocytes
3. Formation of woven bone (immature spongy bone) and
periosteum rich in blood supply
4. Compact bone (Lamellar bone) replaces immature spongy bone
→ Red marrow fills trabeculae of spongy bone
Skeletal System
Clinical implications
Foetal skull
Fontanelles (little fountains)
§ Soft fibrous membranes of the skull that
ossify after birth
§ Anterior fontanelle – diamond shaped
closes over at 1½ - 2 years
Bone Tissue
Deposition & Removal of Bone
Skeletal System
Altered bone growth Achondroplastic Dwarfism –
affects endochondral ossification (long bone growth)
Marfan’s Syndrome Pituitary Dwarfism
genetic disorder affecting connective ↓ GH during childhood growth
tissue (impacts intramembranous & endochondral ossification)
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Skeletal System
1. Hormonal
§ parathyroid hormone (PTH)
§ calcitonin
2. Mechanical stress
Skeletal System
Learning Objectives
Human Skeleton
1. Axial skeleton (green)
3 regions that forms the longitudinal axis
i. skull
ii. vertebral column
iii. thoracic cage
§ sternum
§ ribs
2. Appendicular skeleton (gold)
“Appended” to the axial skeleton
§ pectoral girdle
§ pelvic girdle
§ upper limbs
§ lower limbs
i. Skull
§ Cranial Cavities
§ Cranial
§ Orbital (8 x bones)
§ Nasal
§ Oral
(14 x bones)
i. Skull (2 x)
(1 x)
Activity:
‘Label and Learn’
§ Identify & label these
Frontal
cranial bones Parietal
§ frontal
§ parietal Sphenoid
Temporal
§ temporal
§ sphenoid
Ethmoid
§ ethmoid
Activity:
‘Label & Learn’
§ In this posterior view of Sagittal suture
the skull, identify & label
the following: Parietal
§ sagittal suture bone
§ parietal bones Lambdoid
§ occipital bone suture
§ lambdoid suture
§ mastoid processes Occipital
bone Mastoid
§ external occipital process
protuberance
external occipital
protuberance
i. Skull
View = Anterior view
§ Facial bones (14)
§ nasal (2)
§ lacrimal (2)
§ zygomatic (2)
§ maxilla (2)
§ mandible (1) ‘Keystone’
§ vomer (1)
§ inferior nasal concha (2)
§ palatine (2)
Activity:
‘Label & Learn’
§ Identify & label these facial
bones:
§ nasal
§ lacrimal
§ zygomatic
§ inferior nasal concha
§ maxilla
§ mandible
§ vomer
Answers
i. Skull
View = Lateral
§ Cranial
§ temporal
§ parietal
§ frontal
§ occipital
§ sphenoid
§ ethmoid
§ Facial
§ Nasal (x 2)
§ Lacrimal (x 2)
§ Zygomatic (x 2)
§ Maxilla (x 2)
§ Mandible ( x1)
Activity:
‘Label & Learn’
How many facial
and cranial bones
bones can you
name in this view?
i. Skull
View = Medial
(midsagittal section)
§ Anterior cranial floor
frontal bone
§ Middle cranial floor
sphenoid bone
§ Posterior cranial
floor occipital bone
Activity:
‘Label & Learn’
How many facial &
cranial bones
bones can you
name in this
midsagittal view?
i. Skull
View = Inferior
Special features
§ foramen magnum “large
hole” - spinal cord
§ occipital condyles –
articulates with 1 st vertebrae
§ palatine bones – forms
posterior hard palate
§ jugular foramen – “hole” for
jugular vein
§ carotid canal – opening for
carotid artery
i. Skull
§ How many cranial and
facial bones and/or Which 2 bones form
the hard palate?
features can recognise
from this inferior view of the
skull?
i. Skull
View = Superior
§ Base of the cranial
cavity.
§ Special features:
§ crista galli
(ethmoid)
§ sella turcica
(sphenoid)
Sphenoid bone
Cranial Bone
Sphenoid bone
Cranial Bone
Activity:
Identify the
features
Ethmoid bone
§ Deepest bone in skull
§ Cribriform plate - forms roof of nasal cavity and floor of anterior cranial
fossa
Cranial Bone § Cribriform plates – contain tiny holes (“foramina”) for olfactory nerves
to pass through
§ Cristi galli - ‘rooster’s comb’ attached to dura mater (outer most
meningeal layer of brain)
Mandible & Maxilla
Facial Bones
§ Mandible (Lower)
largest and strongest in face
Ment = chin
§ Maxilla (Upper)
§ 2 x bones fused medially
(pleural = maxillae)
§ articulates with all facial
bones (except mandible)
Mandible
Paranasal Sinuses
Air-filled spaces in the bones of the
skull (mucosa-lined)
§ Why ?
Learning Objectives
Human Skeleton
1. Axial skeleton (green)
3 regions that forms the longitudinal axis
i. skull
ii. vertebral column
iii. thoracic cage
§ sternum
§ ribs
2. Appendicular skeleton (gold)
“Appended” to the axial skeleton
§ pectoral girdle
§ pelvic girdle
§ upper limbs
§ lower limbs
ii. Vertebral column
A B C
4
5 visiblebody.com
What is
Abnormal about
these spinal
curvatures?
§ Scoliosis (A) - “twisted
disease” abnormal lateral
curvature
§ Kyphosis (B) -
“hunchback” dorsally
exaggerated thoracic
curvature
§ Lordosis (C) -
“swayback” accentuated
lumbar curvature
*Tilt your head
forw ard. Feel the
bony process on the
Vertebra
Typical vertebra structures:
1. body
2. vertebral arch
§ lamina
§ pedicle
3. vertebral foramen
4. spinous process
5. transverse process
Activity:
‘Label and Learn’
Answers:
‘Label and Learn’
§ C1-C7
§ Smallest; lightest
§ The body is oval
§ Vertebral foramen - large,
triangular
§ Transverse process contains
transverse foramen
§ T1-T12
§ Articulate with ribs
§ Body – heart shaped
§ Contains costal facets
(inferior/superior)
§ Vertebral foramen - circular
§ Spinous process – longer &
points inferiorly (downward)
Herniated disc ?
Rupture of anulus fibrosus (can
be very painful)
Coccyx “tailbone”
§ Small triangular bone
fuses with sacrum
§ 4 bones (sometimes 3-
5 bones)
§ Greek for “cuckoo”
Learning Objectives
ü Describe the composition of the pectoral girdle and its attachment to the axial skeleton
ü Identify structural features of the scapula
ü Identify structural features of the clavicle
ü Identify structural features of the humerus
ü Identify structural features of the forearm
ü Identify the carpal bones of the wrist
Human Skeleton
1. Axial skeleton (green)
3 regions that forms the longitudinal axis
i. skull
ii. vertebral column
iii. thoracic cage
§ sternum
§ ribs
2. Appendicular skeleton (gold)
“Appended” to the axial skeleton
§ pectoral girdle
§ pelvic girdle
§ upper limbs
§ lower limbs
3
Appendicular Skeleton Sternoclavicular
joint
Pectoral girdle
View = Anterior
§ Each pectoral girdle consists of 2 bones (pectus = breast)
§ clavicle - anteriorly
§ scapula – posteriorly
§ pectoral girdle is incomplete…..Why?
§ girdle refers to a belt like structure encircling the
body
§ sternoclavicular joint
§ only attachment to axial skeleton
§ Enables humans to carry out movement (throw a ball,
climbing, use our phone)
§ mobility > stability
Pectoral Girdle
clavicle
Pectoral Girdle
Scapulae
§ 3 Borders
§ superior
§ lateral
§ medial
§ Anterior – special features
§ coracoid process (corac = “beaklike”)
§ glenoid cavity
§ subscapular fossa (sub = below)
§ Posterior
§ spine of the scapula
§ acromion process
§ supraspinous fossa
§ infraspinous fossa
*TIP: Learn the prefix’s to help you with identifying bone features*
6
Pectoral Girdle
Scapulae
§ 3 Borders
§ superior
§ lateral
§ medial
§ Anterior
§ coracoid process
§ glenoid cavity
§ subscapular fossa
§ Posterior – special features
§ spine of the scapula
§ acromion process
§ supraspinous fossa (supra = above)
§ infraspinous fossa (infra = below)
*Learning the prefix’s will help you with identifying bone features*
Upper limb
Humerus
§ Typical long bone, articulates with scapulae
(proximal) at shoulder and radius/ulna (distal)
§ Special features - Anterior view
§ head (HOH)
§ anatomical neck
§ greater tubercle
§ lesser tubercle
§ intertubercular sulcus (inter = between)
§ deltoid tuberosity
§ capitulum (lateral condyle)
§ trochlea (medial condyle)
§ medial epicondyle (epi = on top)
§ lateral epicondyle
9
Upper limb
Humerus
§ Special features - Posterior view
§ head (HOH)
§ anatomical neck
§ surgical neck
§ deltoid tuberosity
§ olecranon fossa
§ medial epicondyle
§ lateral epicondyle
§ trochlea
10
Activity
‘Label & Learn’
11
Upper limb
Radius & Ulna
§ Forearm (2 parallel long bones)
§ Radius
§ head (biceps brachii
attaches here)
§ radial tuberosity
§ radial styloid process
§ Ulna (elbow)
§ olecranon
§ ulnar styloid process What bone does the olecranon
§ interosseous membrane - articulate with?
connecting ligament
12
Activity
‘Label & Learn’
1. radius
2. radial head
3. radial tuberosity
4. radial styloid
process
5. ulna
6. olecranon
7. ulna styloid
process
8. interosseous
membrane
13
Upper limb
Hand
§ Carpus (wrist)
§ 8 carpal bones (wrist)
- short bones
§ Metacarpals (palm)
§ 5 metacarpals
§ Phalanges
§ 14 phalanges
(fingers)
§ 3 in digits 2-5
§ 2 in thumb
14
15
MODULE 1
Skeletal System
Topic 1.3b:
Appendicular skeleton:
Pelvic girdle and Lower limb
Learning Objectives
ü Describe the composition of the pelvic girdle and its attachment to the axial skeleton
Human Skeleton
1. Axial skeleton (green)
3 regions that forms the longitudinal axis
i. skull
ii. vertebral column
iii. thoracic cage
§ sternum
§ ribs
2. Appendicular skeleton (gold)
“Appended” to the axial skeleton
§ pectoral girdle
§ pelvic girdle
§ upper limbs
§ lower limbs
Appendicular Skeleton
Pelvic girdle
§ Complete girdle = 2 x hip bones +
sacrum
Appendicular Skeleton
Pelvic girdle
Hip bones - important features
1. Ilium (hands on hips):
§ iliac crest;
§ greater sciatic notch
§ anterior and posterior
superior iliac spine
2. Ischium (sitting bone)
§ lesser sciatic notch;
§ ischial spine
§ obturator foramen
3. Pubis (pubic bone)
§ obturator foramen
Appendicular Skeleton A
Activity: ‘Label and Learn’
Appendicular Skeleton
Pelvic Structure (Male vs. Female)
[A] Female [B] Male
Appendicular Skeleton
Pelvic Structure (Male vs. Female)
[A] Female [B] Male
Coccyx
Male: less movable, projects anteriorly
Female: more movable, projects
inferiorly (why?)
3
Male vs.
Female
Pelves
Pelvic inlet
Male: Narrow; Heart shaped
Female: wide; oval shaped
Appendicular Skeleton
Lower limb - Thigh
Femur (thigh)
- Largest, longest, strongest bone.
- Surrounded by bulky muscles
§ head
§ neck
§ greater & lesser trochanter
§ gluteal tuberosity
§ linea aspera
§ epicondyles - lateral and medial (Epi – upon)
§ condyles - lateral and medial
Patella (kneecap) – sesamoid bone
§ protects the knee joint
§ apex (anterior)
Activity
‘Label & Learn’
A B
i. Tibia
§ tibial plateau
§ tibial tuberosity
§ condyles - medial &
lateral
§ medial & lateral
malleolus
ii. Fibula
§ head
§ lateral malleolus
Activity
‘Label & Learn’
A B
Appendicular Skeleton
Lower Limb - Foot
i. Tarsals (7 x bones)
§ 2 largest
§ talus
§ calcaneus
ii. Metatarsals (5 x)
§ long bones
ii. Phalanges (14 x)
§ toes
Learning Objectives
What is a Joint?
§ Movements (football, ballet,
running) all made possible by joints
§ Joint = an articulation where 2
bones meet
§ What do they help with?
§ mobility
§ stability
§ Vulnerable? yes, they are the
weakest part of the skeleton
§ Classification is via
(i) structure AND (ii) function
Joint classification
Structure
Synchondroses
2. Cartilaginous Joints
§ Bones joined by cartilage
§ No joint cavity
§ Not highly movable
§ 2 types of of cartilaginous joint Symphyses
§ Synchondroses (plate of
hyaline cartilage)
§ Symphyses (fibrocartilage
unites bones. Acts as
shock absorber)
Structure
3. Synovial Joints
§ Bones separated by fluid-filled joint cavity
§ Freely movable diarthroses
§ 6 key features:
§ Articular cartilage : glassy smooth hyaline
cartilage ends of bone)
§ Joint (articular) cavity: a space containing
synovial fluid
§ Articular capsule: joint cavity enclosed by a 2
layered articular capsule
§ Synovial fluid: slippery fluid found in free spaces
(reduces friction)
§ Ligaments: reinforce and strengthen the joint
§ Nerves and blood vessels: richly supplied
Gliding at the
Movements wrist
Movements Flexion
Abduction/
Rotation
adduction
Movements
Synovial Joints
Special Body Movements
§ Don't fit into the other categories
(gliding, rotation or angular)
§ Pronation/supination
§ Opposition
§ Dorsiflexion/ plantarflexion
§ Inversion/eversion
§ Protraction/retraction
Synovial Joint
Shapes Plane joints Condylar joints
6 types
Q. Name the category of each of the synovial joints illustrated and their
movement (i.e. according to shape and movement)
Synovial Joint
Knee
§ Largest and most complex joint in body
§ Single joint cavity,
§ But consists of 3 joints in 1!
§ Tibiofemoral (lateral and medial)
§ hinge joint (bicondylar: flex/ext,
some rotation when partially flex)
§ Patellofemoral (patella & femur)
§ plane joint (gliding)
§ Bursa – fluid filled sacs (reduce friction)
§ Menisci – outer margins, prevent side to
side rocking and are shock absorbers
Synovial Joint
Knee
§ Ligaments – strengthen and reinforce
the joint
§ Anterior view = Capsule absent
§ 3 broad ligaments
§ Patellar ligament (tapped in
knee-jerk reflex
§ Medial patellar retinaculum
§ Lateral patellar retinaculum
Synovial Joint
Knee
§ Anterior (absent capsule)
§ Patellar ligament
§ Extracapsular ligaments (import for prevent lat/med
rotation when knee extended)
§ Tibial (medial) collateral ligament (MCL)
§ Fibula (lateral) collateral ligament (LCL)
§ Intracapsular ligaments
§ cruci = cross (X marks the spot)
§ Anterior cruciate ligament (ACL) – prevents forward
sliding of tibia on femur
§ Posterior cruciate ligament (PCL) – prevents forward
sliding of femur (or tibia going backwards)
Activity:
Tibial
‘Label & Learn’ collateral
ligament
§ Name the ligaments of the knee:
Anterior Posterior
§ Anterior (absent capsule) cruciate cruciate
ligament ligament
§ Intracapsular
§ Extracapsular Fibula
collateral
ligament
Patellar
ligament
Synovial Joint
Summary: Knee
§ Tendons
§ Semimembranosus
§ Gastrocnemius
§ Muscle
§ Popliteus
§ Ligaments
§ Oblique popliteal ligament
§ Arcuate popliteal ligament
§ Tibial collateral ligament (MCL)
§ Fibula collateral ligament (LCL)
Knee “Unhappy Triad”
1. Tibial Collateral Ligament (MCL)
2. Medial Meniscus
3. Anterior Cruciate Ligament (ACL)