Gowdaman Vasdevan Ph.D.

Address for communication:

B2 Annanagar, Opp. To MS Residency, Peelamedu, Coimbatore - 641004
E-mail: [email protected]; Mobile: +91 9894712373
Educational Qualification
S.No. Degree Specialization University Year of Percentage
passing
1. Ph.D. Biotechnology Bharathiar University 2013 NA
2. M.Sc. Applied Microbiology Bharathiar University 2007 73.71
3. B.Sc. Microbiology Bharathiar University 2005 76.40

Research Experience – Total: 5 years, 2 months

1. Genomics (Apr 2021 to till date)
Place: Ganga Research Centre, Ganga Orthopaedic Research & Education Foundation,
Coimbatore.
Supervisor: Dr. S. Rajasekaran, Chairman, Dept of Orthopaedics, Trauma & Spine Surgery.
Ganga Hospitals and Medical Centre.
Focus on: Low back pain pathophysiology with respect to IVD disc Microbiome and Gut
Microbiome dysbiosis using OMICS approach.
Achievements:
 Identification of Bacterial metabolites in IVD samples using metabolomics and the
research paper published in the Spine Journal.
 Establishment of Gut dysbiosis and Lumbar disc degeneration work in progress.

2. Research Associate (June 2015 to Feb 2017)

Place: Agharkar Research Institute, Pune.
Supervisor: Dr. P. k. Dhakephalkar, Director
Title: “Development of Bioremediation process for petroleum hydrocarbon contaminated sites
using powdered microbial consortia” - IRS-ONGC project.
Achievements:
 Developed bacterial consortia capable of bioremediation of crude oil (10% concentration)
upto 88% within 5 months.
 Identified a novel bacterium Xylanimonas sp. Nov. that can efficiently degrade aromatic
hydrocarbons.
 Isolation of bacteria that can efficiently degrade different fractions of crude oil.

3. Research Associate (Mar 2013 to Dec 2014)

Place: BITS Pilani KK Birla Goa campus, Goa, India;
Supervisor - Dr. Srikanth Mutnuri, Professor, Biological Sciences.
Title: “Analysis of metabolically active bacterial speciesin anaerobic digesters”-CSIR Project-
Analysis of methanogenic diversity in anaerobic digester using DNA-SIP.
Output: Identified an effective methanogen that can tolerate psychrophilic conditions.
Isolation of methanogens from different anaerobic digesters using roll tube method.

Industry Experience – Total: 3 years, 3 months

1. Scientist - Genomics Technologies (Jan 2018 to Mar 2021)
Place: Raygenome Labs Pvt. Ltd. (Formerly Megavision Life Sciences Pvt. Ltd) Pune.
R&D Focus:
R&D for RT-PCR based and Sanger based mutation assay development for Oncology,
Nutrigenomics, and Infectious diseases. Next-Generation Gene panel designing for Oncology.
Production:
Carrying out Oncology and Nutrigenomics samples for Gene panels using NGS and RT-PCR,
data analysis, reporting and troubleshooting if any.
Achievements:
 Established NABL accredicted Testing lab for testing RNA viruses using Real-Time RT-
PCR – COVID19 testing.
 Established Advanced Molecular Genomics Lab to Clients and trained staffs for Oncology
gene panels assays.
 Improved the efficiency of using the software tool used for Database development for
Pharmacokinetics.
Research projects:
Sancheti Hospital and Personome Inc., Pune, India; Supervisor - Late Dr. Ketan Khurjekar.
Duration - Sept 2018 to Sept 2019.
Title: “Genomic profiling of vertebral metastases in Indian population and their clinical
association with the candidate genes” - AOSPINE research project
Equipment handled: Next Generation sequencing using Ion Torrent PGM machine (Thermo).

Invited Talks
1. Lead lecturer - on "From Lab to Land - A Microbial Journey" during the International
Alumni Conference organized by the Department of Microbiology on 28th Oct, 2022
supported by PSGCARE.
2. Guest speaker – NGS platform in clinical research – Ion Torrent Sequencer, during
GOREF-DBT workshop on NGS-16S metagenome, from sample to data (NMSD), 17-18 th
December, 2021.

Publications: Total Impact factor – 25.416

1. Lanjekar, V.B., Hivarkar, S.S., Vasudevan, G. et al. Actinomyces ruminis sp. nov., an
obligately anaerobic bacterium isolated from the rumen of cattle. Arch Microbiol 205, 9
(2023). (IF – 2.667)
2. Rajasekaran, S., Tangavel, C., Vasudevan, G., Easwaran, M., Muthurajan, R., KS, S. V.
A., ... & Shetty P. (2022). Bacteria in human lumbar discs–subclinical infection or
contamination? Metabolomic evidence for colonization, multiplication, and cell-cell cross-
talk of bacteria. The Spine Journal. (IF – 4.297)
3. Singh, Purnima; Kapse, Neelam; Gowdaman, Vasudevan; Tsuji, Masaharu; Singh, Shiv
Mohan; Dhakephalkar, Prashant K (2021) Comparative Genomic Analysis of Arctic
Permafrost Bacterium Nesterenkonia sp. PF2B19 to Gain Insights into Its Cold Adaptation
Tactic and Diverse Biotechnological Potential. Sustainability 13(8), 4590. (IF – 3.889)
4. Kapse NG*., Engineer AS*., Gowdaman V*., Wagh S., Dhakephalkar PK (2019).
Functional annotation of the genome unravels probiotic potential of Bacillus coagulans
HS243. Genomics 111 (4), 921-929 (* Equal contribution) (IF – 4.31)
5. Manikandan, M., Gowdaman, V., Duraimurugan, K. and Prabagaran, S.R (2019).
Taxonomic characterization and antimicrobial compound production from Streptomyces
chumphonensis BDK01 isolated from marine sediment. 3 Biotech, 9(5), 167. (IF – 2.893)
6. Kapse NG., Engineer AS., Gowdaman V., Wagh S., Dhakephalkar PK (2018). Genome
profiling for health promoting and disease preventing traits unraveled probiotic potential of
Bacillus clausii B106. Microbiology and Biotechnology Letters, 46(4), 334-345.
7. Joshi, A*., Vasudevan, G*., Engineer, A., Pore, S., Hivarkar, S.S., Lanjekar, V.B.,
Dhakephalkar, P.K. and Dagar, S.S., 2018. Genomic Analysis of Actinomyces sp. Strain
CtC72, a Novel Fibrolytic Anaerobic Bacterium Isolated from Cattle Rumen. Microbiology
and Biotechnology Letters, 46(1), 59-67. (* Equal contribution)
8. Gowdaman, V., & Srikanth, M. (2015). Identification of metabolically active methanogens
in anaerobic digester using DNA stable isotope probing using 13C acetate. Carbon
Science and Technology 2(7):8-16.
9. Vasudevan, G., Siddarthan, V., & Solai Ramatchandirane, P. (2014). Predominance of
Bacillus sp. in soil samples of the southern regions of Western Ghats, India. Annals of
Microbiology 65(1):431-441. doi:10.1007/s13213-014-0876-1. (IF – 3.168)
10. Gowdaman, V., Mathan Kumar, R., Venkatachalam, S., & Prabagaran, S. R. (2014).
Comparison of DNA Fingerprinting analysis for identification of Bacillus species.
International Journal of Research in Advent Technology 2(1):278-288
11. Venkatachalam, S., Gowdaman, V., & Prabagaran, S. R. (2014). Culturable and
Culture-Independent Bacterial Diversity and the Prevalence of Cold-Adapted Enzymes
from the Himalayan Mountain Ranges of India and Nepal. Microbial Ecology 69(3):472-
491. (IF – 4.192)
12. Venkatachalam, S., Sivaprakash, M., Gowdaman, V. & Prabagaran, S. R. (2014).
Bioprospecting of Cellulase Producing Extremophilic Bacterial Isolates from India. British
Microbiology Research Journal 4(2): 138-150.
13. Gowdaman. V., S. Rajeswari & K. Mani (2007). Antimicrobial Metabolites from wood rot
fungus Phellinus hohnelli, Plant Archives 7;763-765.
Book Chapter
1. Nagkirti, P., Shaikh, A., Vasudevan, G., Paliwal, V., & Dhakephalkar, P. (2018).
Bioremediation of Terrestrial Oil Spills: Feasibility Assessment. Optimization and Applicability
of Bioprocesses, 141, Springer Publications

Dissertation:
Ph.D. - Thesis entitled “Bacterial diversity in Western Ghats, South India towards exploring
predominant Bacilli for esterases” was carried out at Department of Biotechnology, Bharathiar
University, Coimbatore (Oct 2007- Sept 2012). Supervisor: Dr. S.R. Prabagaran, Professor,
Bharathiar Univresity, Coimbatore.
M.Sc., Title: “Antibacterial Metabolites from Wood Rot Fungi Phellinus adamantinus and
Phellinus hohnelli” at PSG College of Arts and Science, Coimbatore - UGC Sponsored (Nov
2006 - Apr 2007). Supervisor: Dr. A Michael, Professor, PSG College of Arts and Science,
Coimbatore.

Student projects supervised

Reduction of sulfate wastes using sulfate-reducing bacteria at BITS Pilani KK Birla Goa
campus, Goa - DBT Sponsored - Jan - Apr 2014.
Archaeal diversity in Human Waste Digesters using culture independent approach at
Bharathiar University, Coimbatore - DRDO-DRDE Gwalior sponsored - Jan - Apr 2011.

Technical expertise – Hands-on

 Thermo NGS - Ion Torrent PGM – Bacterial whole genome, 16S metagenome,
 Metatranscriptomics.
 NGS Data analysis: Whole Genome and Metagenome analysis: RAST, MG-RAST,
Spades Assembly and Annotation, Mapping-Pathway tools, QIIME2- mothur.
 QuantStudio 5, BioRad CFX Opus 96 – Taqman and SYBR green assays, Gene
expression, copy number variation, Genotyping.
 BioRad droplet digital PCR – Gene expression assay
 PCR – Multiplex PCR, Nested PCR, Touchdown PCR.
 Kingfisher (Automated DNA/RNA extraction) – Cell free DNA extraction, Nucleic acids
from blood samples.
 Anaerobic chamber – Isolation of methanogens from food waste digesters.
 Ultracentrifuge – DNA-Stable Isotope Probing
 Data analysis - Phylogenetic analysis – PHYLIP, MEGA, BioEdit, EzTaxon, RDP.
 Softwares: DNA STAR, Graphpad Prism, Endnote, MEGA, Phylip, Primer3, Torrent Suite,
Photoshop, MS Office, ISIS/Base, Megan, Peak analyser, MSI, Genotyper, MacOS,
Working experience in Linux (Cent OS and Ubuntu), Online tools for Microbial diversity
and Genomics studies.

I declare that whatever information provided is true to my best knowledge.

(V.GOWDAMAN)