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Recall Questions

This document contains notes from two papers summarizing key points about various pharmacological and pharmaceutical concepts. Some topics covered include: the mechanism of action and side effects of different drug classes like ACE inhibitors, NSAIDs, and opioids; drug interactions; pharmacokinetic concepts like volume of distribution and drug metabolism; and characteristics of specific drugs like atropine, rifampin, and phenytoin. The notes indicate certain topics appeared frequently on past exams like drug binding to plasma proteins and properties of the drug pethidine.

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Aymen Bekir
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Download as DOC, PDF, TXT or read online on Scribd
76 views

Recall Questions

This document contains notes from two papers summarizing key points about various pharmacological and pharmaceutical concepts. Some topics covered include: the mechanism of action and side effects of different drug classes like ACE inhibitors, NSAIDs, and opioids; drug interactions; pharmacokinetic concepts like volume of distribution and drug metabolism; and characteristics of specific drugs like atropine, rifampin, and phenytoin. The notes indicate certain topics appeared frequently on past exams like drug binding to plasma proteins and properties of the drug pethidine.

Uploaded by

Aymen Bekir
Copyright
© © All Rights Reserved
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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Paper one

1. chlorpheniramine is alkylamine derivative


2. ampicillin side chain
3. deficiency in iodine in food leads to cretinism in children
4. a man on tea and toast diet likely to develop iron deficiency anemia
5. zwitter ion structure
6. hyperuricemia occurs more likely in men
7. rheumatoid arthritis leads to cartilage destruction
8. in cystic fibrosis both parents have recessive gene
9. formation of ester occurs by acid alcohol reaction
10. detection of breast cancer attained by mammography
11. determination of chemotherapy dose includes all the following except age factor
12. all are alkylating agents except cytarabine
13. simethicone is silicone derivative
14. somatic nerve is not included in the ANS
15. ACE inhibitors SE is hyperkalemia and increased creatinine
16. ibresartan mech of action
17. Ace inhibitors mode of action
18. action of insulin glagrine is glucose utilization by tisues
19. increased PO4 leads to hypocalcemia
20. psoriasis cha by silvery scales
21. urine output per day is 1500 L
22. glucose reabrosped by tubules
23. oxidation of 2ry alcohol gives ketone
24. phenobarbitone contains keton group
25. c-o-c is ether
26. alkaline phosphate is indicator of liver diseases
27. isoenzyme assay is indicative of tissue necrosis
28. NO anesthesia characterized by rapid induction
29. lignocaine doesn't make CNS stimulation
30. equatorial arrangement
31. phenthiazine general structure
32. paroxetine never used in bipolar disorders
33. quetiapine block 5HT receptors
34. dobutamine acts via B receptor agonism
35. betaxolol decrease aqueous humor production
36. fat soluble vitamins have pronounced toxicity
37. NSAIDs improve mobility in rheumatoid arthritis
38. EDTA is comlexing agent
39. morphine is synthetic opioid
40. metabolism leads to more polar compounds
41. metastatic bone pain is treated by fentanyl patches
42. increase tone of vagal nerve doesn't cause vomiting
43. decrease COX activity increases thromoxane production
44. boric acid has pka 9.24 is very weak acid
45. increase conc NH4cL increases excretion of amphetamine (basic)
46. addition of (CH3)4 to NH4 leads to N+
47. spironolactone is K sparing diuretic
48. metronidazole used in ttt of anaerobic peritonitis
49. vancomycin causes ototoxicity
50. methotrixate antidote is folinic acid
51. erythrocyte is non nucleated cell
52. allopurinol mechanism of action
53. which is not alike:noregestrel, mestronol, progestin, cyproteron
54. in cystic fibrosis there is change in sweat
55. definition of osmotic pressure
56. ciprofloxacin not to be taken with urine alkanizers
57. raloxifene acts on estrogen in bones and lipids
58. blood fastest speed is in artrioles
59. structure of cisplatin
60. tamoxifen side effect is hot flushes
61. acetyl choline is choline ester
62. carbonic anhydrase inhibitors cause metabolic acidosis
63. quinine is an isomer of quinidine
64. organic structure conformation detected by NMR
65. rifampin and phenobarbital are CYP enzyme inducers
66. pethidine(mepridine) take care it comes a lot in exam ,pethidine is the British name-and
Australians adopt the British nomenclature -and you will find it in comprehensive under the name
mepridine because it is the American name exactly like paracetamol-British- and acetaminophen-
American- which refers to the same compound try to know everything about it at least 5 Q's in the
2 papers
67. Ketoprofen is propionic acid derivative

this is what I recall in paper one

Paper 2
1. starch used as disintegrant
2. cellulose acetate phthalate used in enteric coated tablets
3. methadone is morphine agonist
4. pethidine metabolite is toxic
5. autoclaving(3 Q's)
6. phenytoin loading dose
7. combined estrogens CI in breast feeding
8. aspirin is sparingly soluble in water
9. nystatin is not absorbed from GIT
10. atropine dose
11. TPN solution should be refrigerated
12. volume of distribution definition
13. methyl dopa side effect is severe hypotension
14. intraarterial drugs not metabolized by lungs
15. cool tar has photosenstizing action
16. Drug binding to plasma proteins study it well(many Q's)
17. 7 problems 3 : kinetics and 4 pharmaceutical calculations
18. case about cephalothin(v.easy) about 5 Q's
19. another case about anticancer drug-i don't remember it- (tough one) about also 5Q's

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