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April RN 2021

This document contains information on various medical topics including: 1. An electrocardiogram summary describing intervals. 2. Maximum daily dose of paracetamol and dosing for dextromethorphan in children. 3. Risk factors for developing diabetes including family history and physical activity levels can reduce risk. 4. Appropriate anticoagulant is dabigatran for a patient with a CHADS2 score of 5 for atrial fibrillation. 5. Structures of various compounds like salicylic acid, benzodiazepines, and codeine.

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Irshad Ahamad
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0% found this document useful (0 votes)
401 views35 pages

April RN 2021

This document contains information on various medical topics including: 1. An electrocardiogram summary describing intervals. 2. Maximum daily dose of paracetamol and dosing for dextromethorphan in children. 3. Risk factors for developing diabetes including family history and physical activity levels can reduce risk. 4. Appropriate anticoagulant is dabigatran for a patient with a CHADS2 score of 5 for atrial fibrillation. 5. Structures of various compounds like salicylic acid, benzodiazepines, and codeine.

Uploaded by

Irshad Ahamad
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

APRIL 2021

1 – waves heart picture

QT interval : ventricular conductivity


ST segment: Plateau
PR interval : Atrioventricular(AV node) conductivity

2- maximum dose of paracetamol?


4g per day for adults

3- children with dry cough ?


Dextromethorphan
4 to 6 years 15 mg (every 12 hr)
6 to 12 years 30mg (every 12 hr)

4- female with hypertension and dislipidemia , age 50 , BMI normal , her sister has dm
type 1
1)what reduce risk to developing DM : physical activity 3 times per week
2)what risk factor to develop DM : family history
5- CHADS2 score? For atrial fibrillation

What is the appropriate anticoagulant if CHAD score is 5 ? dabigatran

6- structure salicylic acid

2
6- structure benzodiazepines

6- codeine to morphine structure

7 - anticoagulant in pregnant ? heparin

8- side effect amiodarone ?

3
9- type of cost

10 - Dose warfarin ?
Initial dose: 2 to 5 mg orally once a day
Maintenance dose: 2 to 10 mg orally once a day
Target INR: (range: 2 to 3) and 3.5 in valve disease

4
11 - hashimoto's disease? autoimmune disorder can cause Hypothyroidism and the
symptoms is bradycardia
graves’ disease ? hyperthyroidism
cush syndrome ? hypercortisolism
addison’s disease? hypocortisolism
conn’s syndrome? hyperaldosterone

12 -Which drug is banned in sport competitions by international Olympics? Furosemide

13 - HbA1c normal range in pregnancy ? lower than 6%


Diabetes > 6.5%

14 - child with fever?


acetaminophen or ibuprofen
but ibuprofen not for children less than 6 months old
and according to sfda decongested and cough drug not given to child less than 2
years

15- abbreviation after meal ? PC


give gtt o.u TID ? drops in both eyes three times daily

16- route of administration Highest bioavailability ?

17- abbreviation after meal ? PC

18- in pregnancy what the trimester can be use warfarin ?


warfarin category: D avoided use in pregnancy and lactation

19- calculation volume distribution? Vd= dose/c

5
20- what is the name of vit C ? Ascorbic acid
what is biotin? vit B7

22- Preventing Diabetic Foot Ulcer?

23- antidote methotrexate? Leucovorin (folic acid)

24- patient with lithium toxicity?


As antidote: Sodium bicarbonate - Polystyrene sulfonate
Gastric lavage useful if done early
Hemodialysis For severe toxicity

25- antidote of iron? deferoxamine

26- glucose synthesis ? Glucogenesis

27- larger lymphoid organ? spleen

28- surfactant ? lower surface tension between 2 liquids or liquid + gas or liquid
and solid

29- Lubricant ? substance that helps to reduce friction between surfaces in


mutual contact

30- ‫جاب عدد سكان العالم الي انصابو بالسكر وكان عدد بالماليين وكان السؤال ايش‬
‫نسمي هذا الشيء؟ والخيارات‬
prevalence

6
31- drug not use in gout patient ? diuretic (increase uric in blood)

32- drug cause alterations in lipids and liver enzymes evaluated (TG ,LDL, HDL)?
Isotretinoin

33- Women want to be pregnant , she is take thyroxin 100mg and feels fatigue ?
increase dose 125mg

34- to avoid side effect red man syndrome? slow infusion of vancomycin
Ttt : stop the medication and take oral anti histamine
Prevent it : increase infusion time to decrease infusion rate

35- structure diclofenac active metabolite ?

7
36- structures more potent " SSRI "? Paroxetine is the most potent SSRI drug available.

37- antibiotic more sensitive?

8
38- arrows picture

39- which drug can reach milk? less protein binding

40 – vaccines Contraindicated in pregnancy? Any live vaccine such as MMR

41- MMR contraindicated in which allergy ? Egg allergy

9
42- vaccination case : he came for you to take MMR vaccine and history of taking
immunoglobulin for hep a last month what to do ?

a-give immediately
b-tomorrow
c-after 2 months
d- after 6 months

45- why Ibuprofen increase Aspirin bleeding effect? It's cox inhibition

46- Case about parental nutrition and all lab test was normal except magnesium and
potassium it's slightly high and hypophosphataemia ? refeeding syndrome (not sure)

47- Recall bias ?


Recall bias is a type of information bias common in case-control studies where the cases
(or their families) are more likely to recall a prior exposure than the controls

48- bias definition ?


any tendency which prevents unprejudiced consideration of a question
In research, bias occurs when “systematic error [is] introduced into sampling or testing
by selecting or encouraging one outcome or answer over others

10
49- Side effects of drug must update who ? SFDA

50-‫وزاره الصحة بتهتم بأي فئة ؟‬


‫كل المجتمع‬

51- Ondansetron like plant? ginger

52- plant Using for cough ? eucalyptus oil

53- Plant For stress? pomegranate or ginseng

54- Sterile compounding? USP 797

55- Case ,Benign prostatic hyperplasia and developed orthostatic hypotension , he take
prazosin .. what to do ? chose tamsulosin

56- Arterial fibrillation score name? Cha2ds2-vas

57- Case dm with a1c 11% what must have ? chose short and long insulin

58- Case cough with green mucus what should take ? guaifenesin

59- Ceftrixon cross ? liver kidney brain

11
60- Monophase contraceptive ?

61- Contraceptive high estrogen? Transdermal batches

62- Potent accepted shelf-life?

63 A1c check? every 3 months

64- Disinfect gloves? isopropyl 70%

65- Immunosuppressive or bone marrow suppression drug ? chose doxorubicin

66- Anticoagulant with hemodialysis ? Heparin

67- Gentamicin dose ? 1-2

68- Case taking warfarin and other drug and INR high , what is the drug ? Amidarone

12
69- 1gtt uo BID ? One drop in each eye (both eyes) twice a day

70- Favorite otic drug : chose solution


‫قص دهم شو النوع اللي المريض بفضله وسهل االستخدام وكان في خيارات مرهم او اشياء تانية نسيتها‬

71- Graph AUC

72- case about patient take warfarin and he drinks tea during that noticed INR is
decreased then return to the normal when he was stopped it , what the type of this tea?
Green tea

73- question about endocarditis, if all medicines are resistant, except for linezolid, but it
is not acceptable to the FDA. What should you do? Use linzolid as a off
label

13
74- Case that taking about the husband taking sleep pils which is prescribe for his wife
and then the pharmacist wrote in his file that the pt is drug addict asking you what the
mistake done by the pharmacist?
1. Not ask for security
2. Making a diagnosis for the patient

75- ١٠ ‫ يشرب كوفي‬، ‫ سيقارة‬٢٠ ‫ يدخن‬، ‫جاني سؤال يضحك شوي رجال متزوج اثنين‬
‫ السؤال يقول كم عامل من‬.. ‫ و الظاهر عنده هايبرتنشن او شي زي كذا‬، ‫كاسات باليوم‬
‫هاالشياء ان ممكن الرجال تجيه جلطه ؟‬
١ ، ٢ ، ٤ ، ٣ : ‫الخيارات كانت‬
‫ يجيب جلطه او ال‬٢ ‫ عاد مدري انه متزوج‬٣ ‫اخترت‬

76- Gene for clopidogril? (CYP2C19)

77-‫ سؤال عن مريض‬INR 10


‫ولثته فيها نزيف وش نسوي ؟‬
‫اخترت االختبار اللي فيه فيتامين‬ k
‫الباقي مافيهم‬

78- warfarin dose in elderly patient? Consider using lower initial and maintenance dosage

79- Phsopholipid tail and head

14
80- Safe antihypertentive drug for elderly?

81-Disease-induced atherosclerosis?

82-Anti arrhythmic drug interact with Warfarin?

83-Substrate of renin?

84- Pharmacist salary type of cost? Direct medical

85-Prevention dose of alendronate? 5 mg PO daily, or 35 mg PO weekly

86-High intensity statin dose?

15
87 -Dragendroff test? Alkaloids

88-Definition of medication reconciliation?


A process by which a practitioner obtains and documents a complete list of a patient‘s
pre-admission medications and references this list when he or she writes admission,
transfer, and discharge orders

89-Clinical phases before approval? 3 phases

90-Central dogma meaning? is the process by which the instructions in DNA are
converted into a functional product

91-Chlorpromazine mechanism? first-generation antipsychotics (FGAs). It produces its


antipsychotic effect by the post-synaptic blockade at the D2 receptors in the mesolimbic
pathway.

92-Antidote for methemoglobinemia? Methylene blue

93-Drug used for reduce the exacerbation of COPD?

16
94 -valporic acid pregnancy category? D

95- paracetamol antidote after 8 hours of ingestion? NAC

96- structure of TCA and which functional groups responsible of SSRI and SNRI ?

97- name the enzyme responsible for conversion vit D to calcitrol ?


25(OH)D-1α-hydroxylase

98-add carbonyl group to salicylic acid ? *‫ايش اسم العمليه‬

99- HIV and malaria consider as ?


1- chronic disease
2- communcable
3- non_communicable

17
100- type of cell act as cell mediator immunity?

101 -activation of passive immunity by?

102 -If Drug given by wrong rout, given to wrong patient, wrong drug given to patient
Type of error Despensed error Or adminstrative error?

103- ‫في حاله تعقيم الهوت بليت ايش نستخدم ؟‬


Ethanol 70 or 90%
Or isopropnalol 70 or 90%

104 – minor wounds and deep wounds?


Deep w + last dose received within 5 y -- NO ttt
If last dose received more than 5y -- Td only
If unknowns-- Td + TIG

Minor w + if last dose received within 10 y -- NO ttt


If last dose received more than 10 y Td only
If unknowns-- Td only

105 - Drug expire in August 2019 what is the last day of use for it ? 31 August

106 -Information source of vaccine? MOH or WHO or FDA?

107- shortage of medication ? SFDA

18
108 -Mechanism of action for clonidine?
stimulate Alpha2 and activate sympathetic out flow
Or stimulated alpha 2 and inhibits sympathetic outflow

109- counseling point of levothyroxine? Take this medication with water 60 minutes
before breakfast or at bedtime at least 3 hours after your last meal 


110- counseling point of Bisphosphonates?


Take this medication first thing in the morning, before you eat or drink anything, with 6 -
8 oz (1 cup) of plain water.
take this medication while you are sitting up or standing, and the stay upright for at least
30 minutes

111- counseling point of nitroglycerin ?

112- HVP vaccine contraindicated in ? Egg or Neomycin?

113- form of IV Calcium?


Calcium glcuconat

114- Hep b dose ? 0 , 1 , 6 months

115- ...‫مريض معه وصفه والصيدلي رفضها ايش السبب‬


‫اخترت السبب انه في تعديل على كمية‬controlled drug

19
116- ‫ تحويل‬hemecycetine ‫الى‬mithionin ‫ثم الى‬cysteine ... ‫ايش الفيتامين الي‬
‫يعمل‬catalist... B6

117- trastuzumab gene? HER 2

118-licensing narcotic drugs? Ministry Of Interior (MOI)

20
119- Neisseria gonorrhoeae? Gram negative cocci

120- mycobactrium test ? Acid fast bacilli

121- gram positive bacteria? Thick cell wall

122-how use of methotrexate with folic acid ?


Take it the day after methotrexate. ‫مو مع بعض‬

123- women take warfarin and she plans to be pregnant?


Stop warfarin and switch to Enoxaparin

124- ‫متى تبداء تاخذ الحامل الفوليك اسيد اذا كانت تخطط للحمل‬
‫ اشهرقبل الحمل‬3

125- Risperidone cytochrome ?


metabolized to 9-hydroxyrisperidone by the polymorphic cytochrome enzyme P450 2D6
(CYP2D6)

126- Tramadol cytochrome?


It is a prodrug that is metabolized by cytochrome P450 (CYP) enzymes CYP2D6 and
CYP3A4 to its more potent opioid analgesic metabolites,

127 - Antidote for lithium? Sodium bicarbonate - Polystyrene sulfonate

128- Antidote for paracetamol? N-Acetyl cysteine (NAC)

21
129-calcium used with vit D ? Calcium glucont or calcium phosphat?

130- Antibiotic used in entrococci endocaditis ?

131- Antihypertensive contraindicated for elderly? atenolol

132- Duration of antibiotic treatment in case of otitis media?

133- Medication has gene?


Ticlopidon
Golpdigerol
Ticgeroler
Prusegero

134- which is cytokine?


Leukotriene
Adrenaline
Gonadotropin

135- vit b3 deficiency ? Pellagra

136-MOA Liraglutide?
is a glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist) also known as
incretin mimetics. It works by increasing insulin release from the pancreas and decreases
excessive glucagon release.

22
137- MOA of sexaglipten?
a reversible, competitive dipeptidyl peptidase-4 inhibitor, acts by preventing the
degradation of glucagon-like peptide – 1 and hence increases secretion of insulin and
decreases secretion of glucagon.

138- Need renal adjustment ? sitglibtine

139- Contraindicated in ejection fraction HF? pioglitazone

140- Drug for wight loss? orilstate

141- Increase myopathy whenever used with statin? Gemifibrozil

142-Hyperthriodism symptom ? tachycardia

143- Why codeine toxicity ? due to ultra rapid metabolism

145-MOA of Phenobarbital?
increases the amount of time chloride channels are open, which in turn depresses the
central nervous system. This action occurs by acting on GABA-A receptor subunits.

146- Effected by trymine? Linzoled

147- why increase lamotrigine dose gradually ?

23
148- patient with HTN and migraine he can take pseudoephedrine?

149- patient with peptic ulcer and the lab result showed hypomagnesemia due to ? PPI

150- cold room temp or warm room temp? 15-25

151-Phenytoin side effect? gingival hyperplasia

152- women take valproate and she planning to be pregnant? Switch to levetiracetam

153- best route or use of antibiotics IV or Oral ?

154- In description study design why the researcher don't use face-to-face ? Choose this
take a time

155- ‫مريض يستخدم‬warfarien ‫وكان عنده‬


,INR 3 ‫ الى‬2 ‫من‬
‫وفجاءه نزل‬INR ... 1.5 ‫الى‬

156 structure of tertiary and secondary amine in tricyclic antidepressants ?

157- Aspirin bond? covalent bond


Acetaminophen bond? Hydrogen bond

24
158- Which one is double bonds structure ? The answer is C2H4

159- structure of secondary anti histamine? (‫)األسماء تكون مكتوبه‬

25
‫?‪160- alcohol dehydrogenase‬‬

‫واحد حفظ الدواء تبعه بالحمام وباظ ليه؟ ‪161-‬‬


‫الن الحمام رطب ‪Hydrolysis‬‬

‫طب سؤال بعد اذنك ‪162-‬‬


‫ازاي جت الروابط مثال الهيدروجينيه وااليونيه‬
‫االيونية هيقولك مجموعة كاربوكسليك مع مجموعة امينو اما الهيدروجيينة هيدروكسيل مع‬
‫نيتروجين‬

‫‪creatininer‬المسائل بقا سهلة جدا بصراحة عجبتني فكره واحدة بس تحويل بتاعة ‪163-‬‬
‫اني هقسم علي ‪dl 88.42‬اني هحول ميكرو مول لكل لتر الي وحدة مليجرام لكل ‪clearance‬‬
‫دي الفكره كلها‬

‫‪26‬‬
164- Phenytoin equation ?

165- loading dose ?

166- Which statins must be taken at bedtime(night)? Simvastatin and Fluvastatin and
pravastatin

167- ‫لو اضفنا اسبرين لدواء‬amitryptiline


‫ في‬Coat
‫هل دا‬
‫ يزود االمتصاص وال يزود‬duaration ?

27
168- alkaline buffer with aspirin? Decrease absorption or increase absorption or nothing

169- incidence , prevalence calculation?

170- ‫امينو اسيد مهم لو حد عنده‬anorexia ‫يعني انسداد في الشهية مش فاكر االجابات‬
‫بس انا اخترت المختلف فيهم‬

28
180- lipinski rule ?

181 antibiotic for otitis media in pregnant?

182- antibiotics need monitoring for kidney and creatinine?

183- which is cause thrombocytopenia ?

184- ‫سؤال وحده تبغى تشرب‬omeprazole


‫ولقتها منتهيه بتاريخ امس‬
‫ايش تسوي؟ اول اجابه كانت م تشربها والباقي كلها تشربها لالمانه م ادري ايش االجابه الصح‬

29
185- bacteria cause Osteomyelitis ? staphylococcus bacteria

186- Side effect of lamotrigen? N/V, somnolence, rash, tremor, ataxia, impaired
coordination, dizziness, diplopia, blurred vision, alopecia (supplement selenium and zinc)
*Rash (most serious)

187- target hemoglobin in kidney disease on Darbepoetin?

188- active metabolite vitamin D ? 1,25-Dihydroxy vitamin D3

30
189- which organ secretion glucagon ? by alph cell of pancreas

190- tricyclic antidepressants structure?

31
191- Oseltamvir structure?

192- enoxaparin monitoring? anti-Xa level (factor Xa inhibition)

193- Encapsulated bacteria ? is streptococcus pneumonia, Klebsiella, Haemophilus


influenza+Pseudomonas aeruginosa

194- ‫سؤال مين يعالج لك‬nausea ‫اللي تصير بسبب‬bromocriptin as antiparkinsion ?

195- combinations antibiotics in treatment otitis media?

196- T max calculation?

32
197- C max calculation? Cmax = N ( e^ ke * tmax - e^ ka * tmax)

198 tough level of vancomycin? 10-20 mg/L


15-20 mg/L for serious infections

199- essential amino acid?

200- dragendorf test? alkaloid

201- case about snack bite ?


Anti-venom for snack
And neostigmine for tachycardia

33
183- picture of what ? what is its natural derivative treatment?
Malaria – Quinine

34
183- malaria treatment in KSA ?

117- 2029/5/31 ‫ وصل لعندك بتاريخ‬65 ‫كيس لمريض سكر عمره‬


‫استخدم فاكسين‬
Influnza every year
Pnumococcal v before 4year
‫ايش بتجيب له االن‬
Hepatitis A and hep B
Or MMR and Bcg
‫اخترت األول‬

35

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