APRIL 2021
1 – waves heart picture
QT interval : ventricular conductivity
ST segment: Plateau
PR interval : Atrioventricular(AV node) conductivity
2- maximum dose of paracetamol?
4g per day for adults
3- children with dry cough ?
Dextromethorphan
4 to 6 years 15 mg (every 12 hr)
6 to 12 years 30mg (every 12 hr)
4- female with hypertension and dislipidemia , age 50 , BMI normal , her sister has dm
type 1
1)what reduce risk to developing DM : physical activity 3 times per week
2)what risk factor to develop DM : family history
5- CHADS2 score? For atrial fibrillation
What is the appropriate anticoagulant if CHAD score is 5 ? dabigatran
6- structure salicylic acid
2
6- structure benzodiazepines
6- codeine to morphine structure
7 - anticoagulant in pregnant ? heparin
8- side effect amiodarone ?
3
9- type of cost
10 - Dose warfarin ?
Initial dose: 2 to 5 mg orally once a day
Maintenance dose: 2 to 10 mg orally once a day
Target INR: (range: 2 to 3) and 3.5 in valve disease
4
11 - hashimoto's disease? autoimmune disorder can cause Hypothyroidism and the
symptoms is bradycardia
graves’ disease ? hyperthyroidism
cush syndrome ? hypercortisolism
addison’s disease? hypocortisolism
conn’s syndrome? hyperaldosterone
12 -Which drug is banned in sport competitions by international Olympics? Furosemide
13 - HbA1c normal range in pregnancy ? lower than 6%
Diabetes > 6.5%
14 - child with fever?
acetaminophen or ibuprofen
but ibuprofen not for children less than 6 months old
and according to sfda decongested and cough drug not given to child less than 2
years
15- abbreviation after meal ? PC
give gtt o.u TID ? drops in both eyes three times daily
16- route of administration Highest bioavailability ?
17- abbreviation after meal ? PC
18- in pregnancy what the trimester can be use warfarin ?
warfarin category: D avoided use in pregnancy and lactation
19- calculation volume distribution? Vd= dose/c
5
20- what is the name of vit C ? Ascorbic acid
what is biotin? vit B7
22- Preventing Diabetic Foot Ulcer?
23- antidote methotrexate? Leucovorin (folic acid)
24- patient with lithium toxicity?
As antidote: Sodium bicarbonate - Polystyrene sulfonate
Gastric lavage useful if done early
Hemodialysis For severe toxicity
25- antidote of iron? deferoxamine
26- glucose synthesis ? Glucogenesis
27- larger lymphoid organ? spleen
28- surfactant ? lower surface tension between 2 liquids or liquid + gas or liquid
and solid
29- Lubricant ? substance that helps to reduce friction between surfaces in
mutual contact
30- جاب عدد سكان العالم الي انصابو بالسكر وكان عدد بالماليين وكان السؤال ايش
نسمي هذا الشيء؟ والخيارات
prevalence
6
31- drug not use in gout patient ? diuretic (increase uric in blood)
32- drug cause alterations in lipids and liver enzymes evaluated (TG ,LDL, HDL)?
Isotretinoin
33- Women want to be pregnant , she is take thyroxin 100mg and feels fatigue ?
increase dose 125mg
34- to avoid side effect red man syndrome? slow infusion of vancomycin
Ttt : stop the medication and take oral anti histamine
Prevent it : increase infusion time to decrease infusion rate
35- structure diclofenac active metabolite ?
7
36- structures more potent " SSRI "? Paroxetine is the most potent SSRI drug available.
37- antibiotic more sensitive?
8
38- arrows picture
39- which drug can reach milk? less protein binding
40 – vaccines Contraindicated in pregnancy? Any live vaccine such as MMR
41- MMR contraindicated in which allergy ? Egg allergy
9
42- vaccination case : he came for you to take MMR vaccine and history of taking
immunoglobulin for hep a last month what to do ?
a-give immediately
b-tomorrow
c-after 2 months
d- after 6 months
45- why Ibuprofen increase Aspirin bleeding effect? It's cox inhibition
46- Case about parental nutrition and all lab test was normal except magnesium and
potassium it's slightly high and hypophosphataemia ? refeeding syndrome (not sure)
47- Recall bias ?
Recall bias is a type of information bias common in case-control studies where the cases
(or their families) are more likely to recall a prior exposure than the controls
48- bias definition ?
any tendency which prevents unprejudiced consideration of a question
In research, bias occurs when “systematic error [is] introduced into sampling or testing
by selecting or encouraging one outcome or answer over others
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49- Side effects of drug must update who ? SFDA
50-وزاره الصحة بتهتم بأي فئة ؟
كل المجتمع
51- Ondansetron like plant? ginger
52- plant Using for cough ? eucalyptus oil
53- Plant For stress? pomegranate or ginseng
54- Sterile compounding? USP 797
55- Case ,Benign prostatic hyperplasia and developed orthostatic hypotension , he take
prazosin .. what to do ? chose tamsulosin
56- Arterial fibrillation score name? Cha2ds2-vas
57- Case dm with a1c 11% what must have ? chose short and long insulin
58- Case cough with green mucus what should take ? guaifenesin
59- Ceftrixon cross ? liver kidney brain
11
60- Monophase contraceptive ?
61- Contraceptive high estrogen? Transdermal batches
62- Potent accepted shelf-life?
63 A1c check? every 3 months
64- Disinfect gloves? isopropyl 70%
65- Immunosuppressive or bone marrow suppression drug ? chose doxorubicin
66- Anticoagulant with hemodialysis ? Heparin
67- Gentamicin dose ? 1-2
68- Case taking warfarin and other drug and INR high , what is the drug ? Amidarone
12
69- 1gtt uo BID ? One drop in each eye (both eyes) twice a day
70- Favorite otic drug : chose solution
قص دهم شو النوع اللي المريض بفضله وسهل االستخدام وكان في خيارات مرهم او اشياء تانية نسيتها
71- Graph AUC
72- case about patient take warfarin and he drinks tea during that noticed INR is
decreased then return to the normal when he was stopped it , what the type of this tea?
Green tea
73- question about endocarditis, if all medicines are resistant, except for linezolid, but it
is not acceptable to the FDA. What should you do? Use linzolid as a off
label
13
74- Case that taking about the husband taking sleep pils which is prescribe for his wife
and then the pharmacist wrote in his file that the pt is drug addict asking you what the
mistake done by the pharmacist?
1. Not ask for security
2. Making a diagnosis for the patient
75- ١٠ يشرب كوفي، سيقارة٢٠ يدخن، جاني سؤال يضحك شوي رجال متزوج اثنين
السؤال يقول كم عامل من.. و الظاهر عنده هايبرتنشن او شي زي كذا، كاسات باليوم
هاالشياء ان ممكن الرجال تجيه جلطه ؟
١ ، ٢ ، ٤ ، ٣ : الخيارات كانت
يجيب جلطه او ال٢ عاد مدري انه متزوج٣ اخترت
76- Gene for clopidogril? (CYP2C19)
77- سؤال عن مريضINR 10
ولثته فيها نزيف وش نسوي ؟
اخترت االختبار اللي فيه فيتامين k
الباقي مافيهم
78- warfarin dose in elderly patient? Consider using lower initial and maintenance dosage
79- Phsopholipid tail and head
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80- Safe antihypertentive drug for elderly?
81-Disease-induced atherosclerosis?
82-Anti arrhythmic drug interact with Warfarin?
83-Substrate of renin?
84- Pharmacist salary type of cost? Direct medical
85-Prevention dose of alendronate? 5 mg PO daily, or 35 mg PO weekly
86-High intensity statin dose?
15
87 -Dragendroff test? Alkaloids
88-Definition of medication reconciliation?
A process by which a practitioner obtains and documents a complete list of a patient‘s
pre-admission medications and references this list when he or she writes admission,
transfer, and discharge orders
89-Clinical phases before approval? 3 phases
90-Central dogma meaning? is the process by which the instructions in DNA are
converted into a functional product
91-Chlorpromazine mechanism? first-generation antipsychotics (FGAs). It produces its
antipsychotic effect by the post-synaptic blockade at the D2 receptors in the mesolimbic
pathway.
92-Antidote for methemoglobinemia? Methylene blue
93-Drug used for reduce the exacerbation of COPD?
16
94 -valporic acid pregnancy category? D
95- paracetamol antidote after 8 hours of ingestion? NAC
96- structure of TCA and which functional groups responsible of SSRI and SNRI ?
97- name the enzyme responsible for conversion vit D to calcitrol ?
25(OH)D-1α-hydroxylase
98-add carbonyl group to salicylic acid ? *ايش اسم العمليه
99- HIV and malaria consider as ?
1- chronic disease
2- communcable
3- non_communicable
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100- type of cell act as cell mediator immunity?
101 -activation of passive immunity by?
102 -If Drug given by wrong rout, given to wrong patient, wrong drug given to patient
Type of error Despensed error Or adminstrative error?
103- في حاله تعقيم الهوت بليت ايش نستخدم ؟
Ethanol 70 or 90%
Or isopropnalol 70 or 90%
104 – minor wounds and deep wounds?
Deep w + last dose received within 5 y -- NO ttt
If last dose received more than 5y -- Td only
If unknowns-- Td + TIG
Minor w + if last dose received within 10 y -- NO ttt
If last dose received more than 10 y Td only
If unknowns-- Td only
105 - Drug expire in August 2019 what is the last day of use for it ? 31 August
106 -Information source of vaccine? MOH or WHO or FDA?
107- shortage of medication ? SFDA
18
108 -Mechanism of action for clonidine?
stimulate Alpha2 and activate sympathetic out flow
Or stimulated alpha 2 and inhibits sympathetic outflow
109- counseling point of levothyroxine? Take this medication with water 60 minutes
before breakfast or at bedtime at least 3 hours after your last meal
110- counseling point of Bisphosphonates?
Take this medication first thing in the morning, before you eat or drink anything, with 6 -
8 oz (1 cup) of plain water.
take this medication while you are sitting up or standing, and the stay upright for at least
30 minutes
111- counseling point of nitroglycerin ?
112- HVP vaccine contraindicated in ? Egg or Neomycin?
113- form of IV Calcium?
Calcium glcuconat
114- Hep b dose ? 0 , 1 , 6 months
115- ...مريض معه وصفه والصيدلي رفضها ايش السبب
اخترت السبب انه في تعديل على كميةcontrolled drug
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116- تحويلhemecycetine الىmithionin ثم الىcysteine ... ايش الفيتامين الي
يعملcatalist... B6
117- trastuzumab gene? HER 2
118-licensing narcotic drugs? Ministry Of Interior (MOI)
20
119- Neisseria gonorrhoeae? Gram negative cocci
120- mycobactrium test ? Acid fast bacilli
121- gram positive bacteria? Thick cell wall
122-how use of methotrexate with folic acid ?
Take it the day after methotrexate. مو مع بعض
123- women take warfarin and she plans to be pregnant?
Stop warfarin and switch to Enoxaparin
124- متى تبداء تاخذ الحامل الفوليك اسيد اذا كانت تخطط للحمل
اشهرقبل الحمل3
125- Risperidone cytochrome ?
metabolized to 9-hydroxyrisperidone by the polymorphic cytochrome enzyme P450 2D6
(CYP2D6)
126- Tramadol cytochrome?
It is a prodrug that is metabolized by cytochrome P450 (CYP) enzymes CYP2D6 and
CYP3A4 to its more potent opioid analgesic metabolites,
127 - Antidote for lithium? Sodium bicarbonate - Polystyrene sulfonate
128- Antidote for paracetamol? N-Acetyl cysteine (NAC)
21
129-calcium used with vit D ? Calcium glucont or calcium phosphat?
130- Antibiotic used in entrococci endocaditis ?
131- Antihypertensive contraindicated for elderly? atenolol
132- Duration of antibiotic treatment in case of otitis media?
133- Medication has gene?
Ticlopidon
Golpdigerol
Ticgeroler
Prusegero
134- which is cytokine?
Leukotriene
Adrenaline
Gonadotropin
135- vit b3 deficiency ? Pellagra
136-MOA Liraglutide?
is a glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist) also known as
incretin mimetics. It works by increasing insulin release from the pancreas and decreases
excessive glucagon release.
22
137- MOA of sexaglipten?
a reversible, competitive dipeptidyl peptidase-4 inhibitor, acts by preventing the
degradation of glucagon-like peptide – 1 and hence increases secretion of insulin and
decreases secretion of glucagon.
138- Need renal adjustment ? sitglibtine
139- Contraindicated in ejection fraction HF? pioglitazone
140- Drug for wight loss? orilstate
141- Increase myopathy whenever used with statin? Gemifibrozil
142-Hyperthriodism symptom ? tachycardia
143- Why codeine toxicity ? due to ultra rapid metabolism
145-MOA of Phenobarbital?
increases the amount of time chloride channels are open, which in turn depresses the
central nervous system. This action occurs by acting on GABA-A receptor subunits.
146- Effected by trymine? Linzoled
147- why increase lamotrigine dose gradually ?
23
148- patient with HTN and migraine he can take pseudoephedrine?
149- patient with peptic ulcer and the lab result showed hypomagnesemia due to ? PPI
150- cold room temp or warm room temp? 15-25
151-Phenytoin side effect? gingival hyperplasia
152- women take valproate and she planning to be pregnant? Switch to levetiracetam
153- best route or use of antibiotics IV or Oral ?
154- In description study design why the researcher don't use face-to-face ? Choose this
take a time
155- مريض يستخدمwarfarien وكان عنده
,INR 3 الى2 من
وفجاءه نزلINR ... 1.5 الى
156 structure of tertiary and secondary amine in tricyclic antidepressants ?
157- Aspirin bond? covalent bond
Acetaminophen bond? Hydrogen bond
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158- Which one is double bonds structure ? The answer is C2H4
159- structure of secondary anti histamine? ()األسماء تكون مكتوبه
25
?160- alcohol dehydrogenase
واحد حفظ الدواء تبعه بالحمام وباظ ليه؟ 161-
الن الحمام رطب Hydrolysis
طب سؤال بعد اذنك 162-
ازاي جت الروابط مثال الهيدروجينيه وااليونيه
االيونية هيقولك مجموعة كاربوكسليك مع مجموعة امينو اما الهيدروجيينة هيدروكسيل مع
نيتروجين
creatininerالمسائل بقا سهلة جدا بصراحة عجبتني فكره واحدة بس تحويل بتاعة 163-
اني هقسم علي dl 88.42اني هحول ميكرو مول لكل لتر الي وحدة مليجرام لكل clearance
دي الفكره كلها
26
164- Phenytoin equation ?
165- loading dose ?
166- Which statins must be taken at bedtime(night)? Simvastatin and Fluvastatin and
pravastatin
167- لو اضفنا اسبرين لدواءamitryptiline
فيCoat
هل دا
يزود االمتصاص وال يزودduaration ?
27
168- alkaline buffer with aspirin? Decrease absorption or increase absorption or nothing
169- incidence , prevalence calculation?
170- امينو اسيد مهم لو حد عندهanorexia يعني انسداد في الشهية مش فاكر االجابات
بس انا اخترت المختلف فيهم
28
180- lipinski rule ?
181 antibiotic for otitis media in pregnant?
182- antibiotics need monitoring for kidney and creatinine?
183- which is cause thrombocytopenia ?
184- سؤال وحده تبغى تشربomeprazole
ولقتها منتهيه بتاريخ امس
ايش تسوي؟ اول اجابه كانت م تشربها والباقي كلها تشربها لالمانه م ادري ايش االجابه الصح
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185- bacteria cause Osteomyelitis ? staphylococcus bacteria
186- Side effect of lamotrigen? N/V, somnolence, rash, tremor, ataxia, impaired
coordination, dizziness, diplopia, blurred vision, alopecia (supplement selenium and zinc)
*Rash (most serious)
187- target hemoglobin in kidney disease on Darbepoetin?
188- active metabolite vitamin D ? 1,25-Dihydroxy vitamin D3
30
189- which organ secretion glucagon ? by alph cell of pancreas
190- tricyclic antidepressants structure?
31
191- Oseltamvir structure?
192- enoxaparin monitoring? anti-Xa level (factor Xa inhibition)
193- Encapsulated bacteria ? is streptococcus pneumonia, Klebsiella, Haemophilus
influenza+Pseudomonas aeruginosa
194- سؤال مين يعالج لكnausea اللي تصير بسببbromocriptin as antiparkinsion ?
195- combinations antibiotics in treatment otitis media?
196- T max calculation?
32
197- C max calculation? Cmax = N ( e^ ke * tmax - e^ ka * tmax)
198 tough level of vancomycin? 10-20 mg/L
15-20 mg/L for serious infections
199- essential amino acid?
200- dragendorf test? alkaloid
201- case about snack bite ?
Anti-venom for snack
And neostigmine for tachycardia
33
183- picture of what ? what is its natural derivative treatment?
Malaria – Quinine
34
183- malaria treatment in KSA ?
117- 2029/5/31 وصل لعندك بتاريخ65 كيس لمريض سكر عمره
استخدم فاكسين
Influnza every year
Pnumococcal v before 4year
ايش بتجيب له االن
Hepatitis A and hep B
Or MMR and Bcg
اخترت األول
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