DEHYDRATION & FLUID REPLACEMENT
Clinical Signs of Dehydration
Degree of Dehydration Mild Moderate Severe
Infant/Young Child 5% 10% >15%
Older Child/Adolescent 3% 6% >9%
Heart Rate Normal Rapid Rapid
Blood Pressure Normal Normal Decreased
Urine Output Mildly Decreased Markedly Decreased Anuria
Mucous Membranes Moist Tacky Dry
Fontanelles Normal Sunken Markedly Sunken
Capillary Refill Normal (<3s) Normal to Increased Increased (>3s)
(>3s)
Management of Dehydration* 4-2-1 Rule
Mild and Oral Rehydration Up to 10 kg 4mL/kg
Moderate à Fluid: dilute juice or oral rehydration solutions. 40mL + 2mL/kg
10-20 kg
à Continue age-appropriate diet as tolerated. above 10 kg
à Children >6mo can receive a 0.15mg/kg dose
60mL + 1mL/kg
(max dose 8mg) of Ondansetron for >20 kg
above 20 kg
vomiting.
à If ineffective, move to IV hydration.
Example
A 18kg child is 9%
Severe Calculating IV Fluids dehydrated
à STEP 1: Bolus = NS 10-20mL/kg or 5-10mL/kg
if worried about myocardial or renal ü Bolus= 20mL/kg x 18kg =
360mL
dysfunction.
ü Deficit = 0.09 x 18 = 1.62L
à STEP 2: Calculate deficit= % dehydrated x ü Maintenance fluid =
weight in kg. 40mL + 2(8kg) = 56mL/h
à STEP 3: Calculate maintenance fluids in mL/hr ü 24h Total Fluid
with 4-2-1 rule. Replacement Required =
à STEP 4: Calculate Total Fluid Replacement 1620 + (56 x 24) - 360 =
Over 24h = deficit + maintenance – bolus. 2604mL
ü Divide over 24 hours =
à STEP 5: Divide volume over 24 hours.
2604/24 hr = 108.5 mL/hr
à STEP 6: Measure ongoing losses (i.e. vomit, ü Replace losses as
diarrhea, sweat etc.) and replace as needed. needed
à STEP 7: IV Fluid Selection – Typically D5NS ü IV Fluid = D5NS +/-
+/- 20mEq/L KCl depending on kidney function 20mEq/L KCl
and electrolytes.
* Refer to different references for fluid management in infants <28 days old
March, 2022
Grace Georgopoulos (Medical Student, University of Alberta) and Dr. Chris Novak (Pediatrician, Alberta
Children’s Hospital) for www.pedscases.com