Pathophysiology
Thromboembolism occurs when a thrombus, or blood
clot, forms and remains stagnant inside a blood vessel.
Commonly seen in the lower leg, thigh, and pelvis, but
can occur anywhere in the body.
TE is a preventable condition.
CDC, 2020
Risk Factors & Prevention
Three primary factors include venous stasis, activation
of blood coagulation, and vein damage. Clinical Manifestation
o Known as the Virchow triad Edema
Hospitalization and surgery Erythema/discoloration
o 50% of blood clots Warmth
Immobility, old age, increased BMI, family history of TE, Pain
recent or recurrent cancer, pregnancy, estrogen-based Tenderness
medications (hormonal birth control or hormone Calf pain on dorsiflexion (Homan’s sign)
replacement therapy) Palpable venous segment in the extremity
Injury and trauma Thromboembolism Can be asymptomatic
CDC, 2020 Patel & Chun, 2019
CDC, 2019
Evaluation & Treatment
Laboratory tests that are relevant to TE are high-
sensitivity D-timer testing and coagulation studies.
o Prothrombin time and activated partial Integrative Therapy
thromboplastin time INP #3: Nature has healing and restorative properties
Duplex and doppler ultrasounds are the primary that contribute to health and wellbeing (2019).
diagnostic imaging tests for TE. Frequent ambulation outdoors
Treatments for TE include anticoagulation therapies Improved blood flow prevents production of thrombus.
(ex. Heparin and warfarin), pharmacologic Spending time in nature can provide calming and
thrombolysis, compression and anti-embolism relaxing effects.
stockings, mechanical thrombectomy, thrombus
Kreitzer & Koithan, 2019
removal (recommended for iliofemoral vein
Patel & Chun, 2019
thrombosis), angioplasty, stenting of venous
obstructions, and inferior vena cava filters.
Patel & Chun, 2019