National Institute of Pharmaceutical Education and

Research Joint Entrance – 2018

PLEASE NOTE: The questions contained in the given question paper are
completely memory-based. These Questions may or may not match the
actual question paper.

1. Dr. B.C. Ray Award is for

a) Medicine
b) Journalism
c) Pharmacy
d) Physics

2. What is protein content of spirulina

a) 20-30%
b) 70-90%
c) 50-70%
d) 90-100%

3. For what “Golden Rice” were promoted

a) Vit - D
b) Vit - A
c) Vit - E
d) Vit - C

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4. Selegiline is

a) Contraindicated in Parkinson's disease

b) Given in Parkinson's disease and have peripheral alkyne
group
c) Given in Parkinson's disease and have internal alkyne
group
d) None

5. Fluconazole is having ring

a) Imidazole(l,3)
b) Triazole (1,2,3)
c) Triazole (1,2,5)
d) Triazole (1,3,5)

6. Coumarin ring is

a) 2-Benzyl benzopyran - 4 one

b) Chromen-2-one
c) 2-benzopyran-2-one
d) None

7. Which one is used as bitter

a) Kalmegh
b) Glycyrrhiza
c) Senna
d) Digitalis

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8. What is the family of liquorice

a) Apocynaceae
b) Rubiaceae
c) Fabaceae
d) Liliaceae

9. When the world Diabetes Day is celebrated

a) 14 November
b) 1 July
c) 19 October
d) 14 April

10. Indicates used in Fajan's titration

a) Dichlorofluorescein
b) Eriochrome Black - T
c) Crystal Voilet
d) All are correct

11. Which one of the following is BCS class IV drugs

a) Taxol
b) Nafidipine
c) Verapamil
d) Insulin

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12. The dissolution apparatus (USP) used for BCS class IV
drugs

a) USP - I
b) USP - II
c) USP - III
d) USP - IV

13. Who discovered antibiotic Aureomycin

a) Robert Koch
b) Alexander Fleming
c) Yellapragada Subbarow
d) Robert hook

14. What is the product of the given compound in Pinacol-

pinacolone rearrangement

a)

b)
c)
d) None of the above

15. The elemination rate depends upon

a) Plama t1/2
b) Absorption rate

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c) Peak plasma concentration
d) Vd

16. The brand name of Adalimumab which is produced by

Abbott laboratories
a) Humira
b) Ilumya
c) Aimovig
d) Crysvita

17. The eye piece used in electron microscope is made up of

a) Magnetic coil
b) Steel sheet
c) Quartz
d) Glass

18. Residual solvent in pharmaceutical products is detected

by

a) GC
b) HPLC
c) TLC
d) IR

19. The most common binder used with silica gel is

a) Calcium sulphate
b) Calcium Carbonate
c) Acacia
d) Starch

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20. Which one of the following does not contains imidazole
ring

a) Fluconazole
b) Clotrimazole
c) Econazole
d) Fluconazole

21. Which of the following is caused due to deficiency of

factor VIII

a) Haemophilia - A
b) Haemophilia - B
c) Diabetes
d) Cancer

22. Which of the following is Neurodegenerative disease

a) Paget's disease
b) Goiter
c) Addison disease
d) Creutzfeldt- Jakob disease

23. Which of the following is not used as pharmaceutical

preservative

a) Acetic acid
b) Citric acid
c) Salicylic acid
d) Benzoic acid

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24. Resolution of microscope

a) Decrease with increase in RI

b) Increase with increase in RI
c) Remains constant
d) Not fix

25. Which of the following is important for synthesis of

thrombin

a) Vitamin - C
b) Vitamin - K
c) Vitamin A
d) Vitamin E

26. Isoniazid activated by..... enzyme in microbe

a) Kat- G
b) Kat -A
c) Kat- C
d) Kat- D

27. Which of the following is not a vector in genetic

engineering

a) PAC
b) SAC
c) YAC
d) BAC

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28. First genetically engineered plant was

a) Tobacco
b) Oryza sativa
c) Triticum aestivum
d) Potato

29. Which heterocyclic ring present in porphyrin

a) Pyridine
b) Pyrrole
c) Pyridine
d) Imidozole

30. Regulatory body of Japan

a) ANVISA
b) 1FDA
c) PMDA
d) FDA

31. Gallic acid and Catechin present in which tanins

a) Pseudo tannins
b) Hydrolysable tannins
c) Condensed tannins
d) Non-hydrolysable tannins

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32. Which is the system for ADR monitoring used by
USFDA

a) Medwatch
b) Medline
c) Rx
d) None

33. Rickets occurs due to

a) Bacteria
b) Virus
c) Unpaired metabolism of vit-D
d) Unpaired metabolism of vit-C

34. In titration of Ferrous gluconate tablet following is used

as indicator

a) KMnO4
b) Ascorbic acid
c) Cerric ammonium nitrate
d) HC

35. Number of carbon atom in stearic acid

a) 16
b) 13
c) 14
d) 18

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36. Gerenyl gerenyl pyrophosphate is used for biosynthesis
of

a) Alcohol
b) Glycoides
c) Terpenoids
d) Tannins

37. Number of isoprene units present in monoterpenes

a) 2
b) l
c) 3
d) 4

38. Number of isoprene units present in triterpenes

a) 6
b) 3
c) 5
d) 30

39. Who founded Oxygen

a) Ranstay
b) Priestley
c) Raman
d) Bentley

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40. Which of the following does not contain any hetrocyclic
ring

a) Nalidixic acid
b) Famoxifin
c) Celexocib
d) All

41. Water in pharmaceutical preparation cam be estimated

by which reagent

a) Karl fischer reagent

b) Potentiometry
c) Conductometry
d) Polarography

42. Which of the following is known as universal detector in

HPLC
a) Flame irrigation detector
b) Rl detector
c) UV spectroscopy
d) All of the above

43. Enzyme lipase is active at which pH in stomach

a) 2-4
b) 4-5
c) 4-7
d) 8-9

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44. Which of the following is soft ionization technique used
in MS

a) Fast Atom Bombardment (FAB)

b) Electrospray ionization (ESI)
c) Atmospheric Pressure Chemical Ionization (APCI)
d) Electron Impact ionization (El)

45. All are phase-1 Rxn except

a) Oxidation
b) Reducation
c) Acetylation
d) Hydrolysis

46. Organ must important for phase-II reaction

a) Liver
b) Skin
c) Small intestine
d) Kidney

47. Synonyms of Ashwagandha

a) Indian balmony
b) Madhunashini
c) Devil dang
d) Winter Cherry

48. The C content of DNA is 35% what is content of T

a) 35%
b) 15%
c) 75%

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d) 30 %

49. Bradikineia is characterized by

a) Slowness in Movement
b) Prepaired muscular
c) Fast movement
d) Involunatary

50. Which is major compound of cotton

a) Cellulose
b) Catechin
c) Waxes
d) Pectic acid

51. In the HLB value is very high, the compound is likely to

used as
a) Solubility enhances
b) o/w emulsifies
c) w/o emulsifies
d) Wetting agent

52. Paralysis agitans is synonyms of

a) Parkinsonism
b) Alzheimer's disease
c) Henson's disease
d) Paget's disease

53. Nipah Virus is spread from… of particular genus)

a) Henipavirus
b) Myxovirus

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c) Abedovirus
d) Retrovirus

54. Pack year is related to

a) COPD
b) Prostate
c) Diabetes
d) Alzheimer

55. 4th generation cephalosporin name

a) Cephazoline
b) Cephaclor
c) Cefepime
d) Cefoxitin

56. Phase-11 reaction occur in

a) Cytoplasm
b) ER
c) Mitochondria
d) None of the above

57. Acid azide converted to isocynide

a) Claisen Rearrangement
b) Curtius rearrangement
c) Backmann rearrangement
d) All of them above

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58. Higuchi plot is draw between

a) Q and t1/2
b) t/Q
c) Q and M
d) None of the above

59. Heckle plot is used to measure

a) Compression preparation
b) Compaction preparation
c) Granulation preparation
d) All of the above

60. DPCO Act was passed in the year

a) 1995
b) 1975
c) 1895
d) 1998

61. Position of N in Purine ring

a) 1,2,3
b) 1,3,7
c) 1,3,8
d) 1,5,7

62. Reagent used in Liebermann burchard test is

a) Acetic Anhydride
b) Boric acid
c) Hydrochloric acid
d) H2SO4

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63. NDA is done after
a) Phase - III
b) Phase - II
c) Phase -1
d) Phase – IV

64. Characteristic of prokaryotic cell is

a) No nucleas envelope
b) Multicellular
c) Ribosome 80S
d) Cell division by mitosis

65. A is two years older than B who is twice as old as C. If

the total ages of A,B and C be 27. what is the age of B
a) 12 years
b) 10 years
c) 8 years
d) 14 years

66. The condition when person is in dream state

(hallucination) and it is difficult to differ between dream
and reality is caused due to
a) Psychedelics
b) Nootropics
c) Neuroleptics
d) All are correct

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67. Ibuprofen comes under schedule
a) G
b) H
c) X
d) C1

68. St. John's wort is the synonyms of

a) Hypericium
b) Belladona
c) Rauwolfia
d) Nux vomica

69. Following adrenergic receptor possess anabolic effect

a) α1
b) α2
c) β1
d) β2

70. Which is microbial insecticide

a) Bacillus thuringiensis
b) Baccilus subtilis
c) Bacillus coagulans
d) All are correct

71. Bacteriophage contain which enzyme

a) Lysozyme
b) Urease
c) Ligase
d) Lipase

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72. Supreme commander of armed force is
a) President of India
b) Prime minister of India
c) Lieutenant General
d) Major General

73. .com is start form of

a) Communication
b) Commercial
c) Common
d) None of them above

74. How many grams of NaOH are needed to make 100 mL

of a 0.5 M solution of NaOH

a) 2 gm
b) 4 gm
c) 6 gm
d) 8 gm

75. In case of proteinurea which of the following is excreted

in urine

a) Acetone and hydroxy butyrate

b) Albumin, Haemoglobin
c) Urea
d) Glucose

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76. The 1st isotherm is explained by with equation

a) BET
b) Kelvin
c) Langmuir
d) None of the above

77. Principle involved in pH mater

a) Potentiometry
b) Conductometry
c) Amperometry
d) None

78. Drug having seven membered ring

a) Pioglitazone
b) Trimipramine
c) Caffine
d) Timolol

79. Inversion of sucrose can be estimated by

a) Polarimeter
b) Potentiometry
c) Conductometry
d) Amperometry

80. Which of the following is not for calculating child dose

a) Young's formula
b) Clerks
c) Dale's
d) Fries formula

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81. Aniline produced in
a) Hoffmann bromamide Rxn
b) Ulmann Reaction
c) Aldol condensation
d) None

82. Which one is used to make new genes by using unrelated

genes
a) Genetic engineering
b) Recombinate DNA technology
c) Gene therapy
d) All of these

83. Which of the following is not the organells of Glycolate

pathway
a) Cytosol
b) Mitochondria
c) ER
d) Peroxysome

84. Which one is most acidic

a)

b)
c)

d)

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85. What is common between Ribozyme and enzyme

a) Both are proteins

b) Both acts as catalyst of Rxn
c) Both reduces rate of rxn
d) None

86. Catachin come under

a) Flavanols
b) Flavone
c) Flavanones
d) Anthocyanine

87. Volatile oil in compounds is estimated by

a) GC
b) HPLC
c) UV Spectroscopy
d) TLC

88. What is angle between hour and minute clock when

watch shows time 4:20
a) 0°
b) 10°
c) 5°
d) 15°

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89. Antonym of mountain would be

a) Valley
b) Plateaus
c) Plains
d) Dome

90. What is the difference between the sterile water and

purified water used in parenterals

a) Sterile water is free from pyrogens

b) Sterile water is free from CO2
c) Sterile water is prepared by distillation
d) None of these

91. Which one of the following is distructive

a) GC
b) HPLC
c) Mass Spectroscopy
d) UV-Spectroscopy

92. In indicator was prepared by mixing phenolprotein,

Methyl Orange, Methyl Red given along with molar
Concentrations the indicator will be used in

a) To estimate approx pH in colorimetery

b) Quantitative estimation
c) Acid-base titrations
d) Potentiometer titrations

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93. Which parameter in polarogaphy does not depends upon
the substrate concentration.
a) Limiting current
b) Decomposition potential
c) Half-wave potential
d) Residual current

94. Which of the antibody is involved in the first line

defence

a) IgG
b) IgA
c) IgE
d) IgM

95. Nitro group is an electron withdrawing group, It directs

the incoming group to the following position for
electrophilic substitution reactions

a) Ipsa position
b) Ortho position
c) Para position
d) Meta position

96. Which intermediate is formed in Wittig's reaction

a) Aldehyde
b) Ketone
c) Betaine
d) Alcohol

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97. Cerebral malaria is treated by

a) Quinine
b) Primaquine
c) Artemisin
d) Chioroquine

98. GFR value for both kidneys is about

a) 120 ml per min

b) 250 ml per min
c) 185 ml per min
d) 150 ml per min

99. Hybridization state present in carbanion is

a) sp3
b) sp2
c) sp
d) sp3d2

100. Muscarinic receptor agonist is

a) Tiotropium bromide
b) Tropicamide
c) Bethanechol
d) Atropine

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