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Erythromycin

Erythromycin is a macrolide antibiotic available under many brand names that is used to treat infections. It works by suppressing bacterial protein synthesis. It is well absorbed orally but absorption varies depending on the salt form, and is distributed widely throughout the body except in the central nervous system. Common side effects include nausea, vomiting, diarrhea and allergic reactions. Nurses should check labels for administration route restrictions and monitor patients during and after administration.

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Kathleen Palomaria
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4K views2 pages

Erythromycin

Erythromycin is a macrolide antibiotic available under many brand names that is used to treat infections. It works by suppressing bacterial protein synthesis. It is well absorbed orally but absorption varies depending on the salt form, and is distributed widely throughout the body except in the central nervous system. Common side effects include nausea, vomiting, diarrhea and allergic reactions. Nurses should check labels for administration route restrictions and monitor patients during and after administration.

Uploaded by

Kathleen Palomaria
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd

DRUG DATA GENERIC NAME: Erythromycin TRADE NAME: Akne-Mycin, Del-Mycin, A/T/S, E/Gel, Erycette, Erygel, Ery-Max, Erysol,

ETS, Staticin, Theramycin Z, T-Stat CONTENTS: Erythromycin MINIMUM DOSE: MAXIMUM DOSE: AVAILABILITY: ROUTES OF ADMINISTRATION: PO, IV

CLASSIFICATION THERAPEUTIC: Anti-infectives PHARMACOLOGIC: macrolides PREGANANCY RISK CATEGORY: B

MECHANISM OF ACTION Suppresses protein synthesis at the level of the 50S bacterial ribosome. Therapeutic effects: bacteriostatic action against susceptible bacteria PHARMACOKINETICS : Absorption: Variable absorption from the duodenum after oral administration (depending on salt form). Absorption of enteric-coated products is delayed. Minimal absorption may follow topical or ophthalmic use. Distribution: Widely distributed. Minimal CNS penetration. Crosses placenta; enters breast milk. Metabolism and Excretion: Partially metabolized by the liver, excreted mainly unchanged in the bile; small amounts excreted unchanged in the urine. Half-life: Neonates:2.1 hr; Adults:1.4-2 hr PHARMACODYNAMI CS: Onset: PO 1 hr IV rapid Peak: PO 1-4 hr IV end of infusion Duration: PO 6-12 hr IV 6-12 hr

INDICATION > > > > > >

CONTRAINDICATION Contraindicated in:

SIDE EFFECTS CNS: seizures CV: qtc prolongation, ventricular arrhythmias EENT: ototoxicity GI: nausea, vomiting, abdominal pain, cramping, diarrhea, druginduced hepatitis, infantile hypertrophic pyloric stenosis, druginduced pancreatitis Derm: rashes Local: phlebitis a IV site Misc: allergic reactions, superinfection

NURSING RESPONSIBILITES BEFORE: >Check brand name labels for administration route restriction > > > > DURING: > > > > > AFTER: > > > > >

SOURCE: Daviss Drug Guide for Nurses 11th Edition, p.498-499

SOURCE: Daviss Drug Guide for Nurses 11th Edition, p.498-499

SOURCE: Daviss Drug Guide for Nurses 11th Edition, p.498-499

SOURCE: Daviss Drug Guide for Nurses 11th Edition, p.498-499

SOURCE: Daviss Drug Guide for Nurses 11th Edition, p.498-499

SOURCE: Daviss Drug Guide for Nurses 11th Edition, p.498-499

SOURCE: Daviss Drug Guide for Nurses 11th Edition, p.498-499

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