Caudal Anaesthesia – Part 2 Notes
Caudal Anaesthesia: Acute Pain Management 2010
Single shot caudal anaesthesia is one of the most widely used techniques
in paediatrics
Provided anaesthesia for lower abdomen, perineum and for lower limbs
High success rate and low rate of complications (in large case series)
Bupivacaine, Ropivacaine and Levobupivacaine all produce similar times
to onset of block and comparable post operative analgesia
Concentration affects effect. 0.175% Ropivacaine provided better
analgesia than lower concentrations but less motor block than higher
doses
Addition of adrenaline to bupivacaine has minimal effect on duration of
analgesia (particularly in older children)
Additives: Morphine does increase duration of block but is associated
with dose dependent adverse effects, the most significant being
respiratory depression. Fentanyl slightly increases duration with less risk
of respiratory depression
Supplementation of GA with caudal block for cardiac surgery decreases
time to extubation and duration of mechanical ventilation but showed no
difference in hospital stay or pain relief
Clonidine @ 1 mcg/kg increased duration of block without adverse
sedation associated with higher doses
Ketamine 0.25 – 0.5 mg/kg provided analgesia without adverse effects
but higher doses causes behavoural problems
There is limited evidence that spinal anaesthesia in place of GA may
reduce the incidence of respiratory complications in premature infants
There is evidence that time to discharge from hospital is reduced with
epidural in place of systemic opioids in fundoplication and patent ductus
arteriosus surgery
Complications: Inadvertent intravascular injection remains the most significant
risk of epidural techniques. There is a risk of injecting into the vascular
medullary space of the sacrum in infancy and childhood due to the cartilaginous
nature of the bone. A UK Audit revealed 5 serious complications in 10633
paediatric epidurals. 2 cases of epidural abscess, 1 case of meningism, severe
postdural puncture headache and a cauda equina syndrome associated with
incorrect drug volume error. Peripheral or Nerve Root Damage was also
reported in 6 additional cases. 3 resolved spontaneously, 2 required gabapentin
and ongoing review but resolved within 12 months, and 1 continued to be
symptomatic beyond 1 year.
Choice of Local Anaesthetic agent1:
Ropivacaine, Levobupivacaine & Bupivacaine are equally efficacious
Bupivacaine is associated with the greatest motor block, whilst
Ropivacaine is associated with the least motor block
Adverse effects are rare and not associated with choice of LA
Caudal in Circumcision2:
There was no difference between requirement for rescue analgesia
between patients receiving parenteral, DNPB or caudal anaesthesia
There was no difference in PONV
Those receiving caudal were much more likely to have motor block and as
such it may be more appropriate for children who are not walking yet
Epidural Test dose in Paediatrics3:
The criteria used for identification of intravascular needle/catheter placement in
adults are not sensitive in paediatrics.
A solution containing 0.5 mcg/kg of adrenaline should be injected slowly and the
following changes should be considered evidence of IV injection:
a HR increase of 10 bpm
an increase of SBP of 15 mmHg or more
an increase of T Wave amplitude of >=25%
1
Canadian Journal of Anaesthesia. 57(12):1102-10, 2010 Dec.
Evidence-based clinical update: Which local anesthetic drug for pediatric caudal block provides optimal efficacy
with the fewest side effects [Review] Dobereiner, Elisabeth F A. Cox, Robin G. Ewen, Alastair. Lardner, David R.
2
Cochrane Database of Systematic Reviews 2008, Issue 4. Art. No.: CD003005. DOI: 10.1002/14651858.CD003005.pub2
Caudal epidural block versus other methods of postoperative pain relief for circumcision in boys. Cyna AM,
Middleton P.
3
1156 Anesth Analg 2001;93:1156–61
Caudal Epidural Block: A Review of Test Dosing and Recognition of Sytemic Injection in Children. Joseph D.
Tobias, MD