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Dobutamine: Uses and Contraindications

Dobutamine is a positive inotropic drug that works by stimulating beta1 receptors in the heart to increase myocardial contractility and cardiac output. It has relatively minor effects on heart rate and arrhythmogenesis. Dobutamine is indicated for short-term inotropic support in cardiac decompensation due to depressed contractility from organic heart disease or cardiac surgery. Contraindications include hypovolemia, acute MI, general anesthesia with certain agents, and pregnancy. Side effects include increased heart rate, blood pressure, arrhythmias, and gastrointestinal symptoms. Nurses monitor patients closely during infusion and adjust the dose based on cardiac output and side effects.

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45 views2 pages

Dobutamine: Uses and Contraindications

Dobutamine is a positive inotropic drug that works by stimulating beta1 receptors in the heart to increase myocardial contractility and cardiac output. It has relatively minor effects on heart rate and arrhythmogenesis. Dobutamine is indicated for short-term inotropic support in cardiac decompensation due to depressed contractility from organic heart disease or cardiac surgery. Contraindications include hypovolemia, acute MI, general anesthesia with certain agents, and pregnancy. Side effects include increased heart rate, blood pressure, arrhythmias, and gastrointestinal symptoms. Nurses monitor patients closely during infusion and adjust the dose based on cardiac output and side effects.

Uploaded by

A.
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
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Mechanism of Nursing

Name of Drug Indication Contraindication Side Effect


Actions responsibilities
Generic Name:
Dobutamine Positive inotropic  For inotropic  Contraindicated  Headache  Monitor
effects are mediated support in the with IHSS;  Increase in HR urine flow,
Brand Name: by beta1-adrenergic short-term hypovolemia increase in cardiac
receptors in the treatment of (dobutamine is systolic BP output,
Classification: heart; increases the cardiac not a substitute  Increase in pulmonary
Sympathomimetic force of myocardial decompensation for blood, ventricular wedge
Beta1 selective contraction with due to depressed plasma, fluids, ectopic beats pressure,
adrenergic agonist relatively minor contractility, electrolytes,  Angina pain ECG and BP
effects on heart rate, resulting from which should be  Palpitations closely
Dosage: arrhythmogenesis; either organic restored prompty during
 Shortness of
2 – 20 mcg/kg/min has minor effects on heart disease or when loss has infusion;
breath
40 mcg/kg/min blood vessels. from cardiac occurred and in adjust dose
 Nausea
surgical any case before and rate
Route: procedures. treatment with accordingly.
IV  Unlabeled uses: dobutamine);
inchildren with acute MI (may  Arrange to
congenital heart increase the size digitalize
disease of the infarct by patients who
undergoing intensifying have atrial
diagnostic ischemia); fibrillation
cardiac general with a rapid
catheterization, anesthesia with ventricular
to augment CV halogenated rate before
function hydrocarbons or giving
cyclopropane dobutamine
whih sensitize the
myocardium to  Use only in
catecholamines; acute
emergencies
pregnancy

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