I MATERIAL SAFETY

DATA SHEET

1,2-DICHLOROETHANE, EXTRA DRY, WATER < 50 PPM

ACC# 00220
Reproduced with permission of Fischer Acros Inc.

SECTION 1—CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

MSDS Name: 1,2-Dichloroethane, extra dry, water <50 ppm

Catalog Numbers: AC326840000, AC326840010, AC326841000,
AC326842500
Synonyms: Ethylene dichloride; 1,2-Ethylene dichloride; Glycol dichloride; EDC;
sym-Dichloroethane; 1,2-Dichloroethane; Ethylene chloride.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the U.S., call CHEMTREC: 800-424-9300

SECTION 2—COMPOSITION, INFORMATION ON INGREDIENTS

CAS# Chemical Name Percent EINECS/ELINCS

107-06-2 1,2-Dichloroethane >99.9 203-458-1

Hazard Symbols: T F
Risk Phrases: 11 22 36/37/38 45

I-1
I-2 APPENDIX I MATERIAL SAFETY DATA SHEET

SECTION 3—HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
Appearance: colorless liquid. Flash Point: 56 deg F. Warning! Flammable liquid
and vapor. May cause central nervous system depression. May cause liver and
kidney damage. May cause cancer based on animal studies. Causes eye and skin
irritation. Causes respiratory tract irritation. Irritant. May be harmful if swallowed.
Target Organs: Central nervous system, liver, eyes, skin.

Potential Health Effects

Eye: Causes eye irritation. Vapors may cause eye irritation. May cause chemical
conjunctivitis and corneal damage.
Skin: Causes skin irritation. May be absorbed through the skin. May cause irritation
and dermatitis. May cause cyanosis of the extremities.
Ingestion: May cause central nervous system depression, kidney damage, and liver
damage. May cause gastrointestinal irritation with nausea, vomiting, and diarrhea.
May cause effects similar to those for inhalation exposure. May be harmful if
swallowed.
Inhalation: Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness, and coma.
Causes respiratory tract irritation. May cause liver and kidney damage. Aspiration
may lead to pulmonary edema. Vapors may cause dizziness or suffocation. Can
produce delayed pulmonary edema. Exposure to high concentrations may produce
narcosis, nausea, and loss of consciousness. May cause burning sensation in the
chest.
Chronic: Possible cancer hazard based on tests with laboratory animals. Prolonged or
repeated skin contact may cause dermatitis. Prolonged or repeated eye contact may
cause conjunctivitis. May cause liver and kidney damage. Effects may be delayed.

SECTION 4—FIRST AID MEASURES

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid.
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2–4
cupfuls of milk or water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breath-
ing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Do NOT use mouth-to-mouth resuscitation.
Notes to Physician: Treat symptomatically and supportively.
APPENDIX I MATERIAL SAFETY DATA SHEET I-3

SECTION 5—FIRE FIGHTING MEASURES

General Information: As in any fire, wear a self-contained breathing apparatus in

pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective
gear. Vapors may form an explosive mixture with air. During a fire, irritating and
highly toxic gases may be generated by thermal decomposition or combustion. Use
water spray to keep fire-exposed containers cool. Flammable liquid and vapor.
Approach fire from upwind to avoid hazardous vapors and toxic decomposition
products. Vapors are heavier than air and may travel to a source of ignition and flash
back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray,
or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant
foam. Water may be ineffective. Do NOT use straight streams of water.
Flash Point: 56 deg F ( 13.33 deg C)
Autoignition Temperature: 775 deg F ( 412.78 deg C)
Explosion Limits, Lower: 6.2%
Upper: 15.9%
NFPA Rating: (estimated) Health: 2; Flammability: 3; Instability: 0

SECTION 6—ACCIDENTAL RELEASE MEASURES

General Information: Use proper personal protective equipment as indicated in

Section 8.
Spills/Leaks: Absorb spill with inert material (e.g., vermiculite, sand, or earth), then
place in suitable container. Avoid runoff into storm sewers and ditches which lead
to waterways. Clean up spills immediately, observing precautions in the Protective
Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide
ventilation. A vapor-suppressing foam may be used to reduce vapors.

SECTION 7—HANDLING AND STORAGE

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse. Ground and bond containers when transferring material. Use spark-
proof tools and explosion-proof equipment. Avoid contact with eyes, skin, and
clothing. Empty containers retain product residue (liquid and/or vapor) and can be
dangerous. Keep container tightly closed. Do not pressurize, cut, weld, braze,
solder, drill, grind, or expose empty containers to heat, sparks, or open flames.
Use only with adequate ventilation. Keep away from heat, sparks, and flame. Avoid
breathing vapor or mist.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Store in a tightly closed container. Keep from contact with oxidizing
materials. Store in a cool, dry, well-ventilated area away from incompatible
I-4 APPENDIX I MATERIAL SAFETY DATA SHEET

substances. Flammables-area. Storage under a nitrogen blanket has been recom-

mended.

SECTION 8—EXPOSURE CONTROLS, PERSONAL PROTECTION

Engineering Controls: Facilities storing or utilizing this material should be equipped

with an eyewash facility and a safety shower. Use adequate general or local
explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits

Chemical Name ACGIH NIOSH OSHA—Final PELs

1,2-Dichloroethane 10 ppm 1 ppm 50 ppm TWA;
TWA TWA; 4 mg/m3 100 ppm Ceiling
TWA 50 ppm IDLH

OSHA Vacated PELs: 1,2-Dichloroethane: 1 ppm TWA; 4 mg/m3 TWA

Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA’s 29 CFR 1910.134
and ANSI Z88.2 requirements or European Standard EN 149 must be followed
whenever workplace conditions warrant a respirator’s use.

SECTION 9—PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid

Appearance: colorless
Odor: chloroform-like
pH: Not available.
Vapor Pressure: 100 mm Hg @29 deg C
Vapor Density: 3.4 (Air¼1)
Evaporation Rate:6.5 (Butyl acetate¼1)
Viscosity: Not available.
Boiling Point: 81–85 deg C
Freezing/Melting Point:
35 deg C
Decomposition Temperature: Not available.
Solubility: Insoluble.
Specific Gravity/Density:1.25 (Water¼1)
Molecular Formula: C2H4Cl2
Molecular Weight: 98.96
APPENDIX I MATERIAL SAFETY DATA SHEET I-5

SECTION 10—STABILITY AND REACTIVITY

Chemical Stability: Stable at room temperature in closed containers under normal

storage and handling conditions.
Conditions to Avoid: Light, ignition sources, excess heat, electrical sparks.
Incompatibilities with Other Materials: Aluminum, bases, alkali metals, ketones,
organic peroxides, nitric acid, strong oxidizing agents, strong reducing agents,
liquid ammonia, amines.
Hazardous Decomposition Products: Hydrogen chloride, phosgene, carbon monox-
ide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

SECTION 11—TOXICOLOGICAL INFORMATION

RTECS#:
CAS# 107-06-2: KI0525000
LD50/LC50:
CAS# 107-06-2:
Draize test, rabbit, eye: 63 mg Severe;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 500 mg/24H Mild;
Inhalation, rat: LC50 ¼ 1000 ppm/7H;
Oral, mouse: LD50 ¼ 413 mg/kg;
Oral, rabbit: LD50 ¼ 860 mg/kg;
Oral, rat: LD50 ¼ 670 mg/kg;
Skin, rabbit: LD50 ¼ 2800 mg/kg; <BR.
Carcinogenicity:
CAS# 107-06-2:
ACGIH: A4—Not Classifiable as a Human Carcinogen
California: Carcinogen; initial date 10/1/87
NIOSH: Potential occupational carcinogen
NTP: Suspect carcinogen
OSHA: Possible Select carcinogen
IARC: Group 2B carcinogen
Epidemiology: IARC Group 2B: Proven animal carcinogenic substance of potential
relevance to humans. IARC Group 2B: No data available on human carcinogen-
icity; however, sufficient evidence of carcinogenicity in animals.
Teratogenicity: See actual entry in RTECS for complete information.
Reproductive Effects: No information found.
Neurotoxicity: No information found.
Mutagenicity: No information found.
Other Studies: See actual entry in RTECS for complete information.
I-6 APPENDIX I MATERIAL SAFETY DATA SHEET

SECTION 12—ECOLOGICAL INFORMATION

Ecotoxicity: Water flea Daphnia: 218 mg/L; 48H; Bluegill/Sunfish: 430 mg/L; 96H;
Static Fathead Minnow: 136 mg/L; 96H; Static—No data available.
Environmental: Terrestrial: Smaller releases on land will evaporate fairly rapidly.
Larger releases may leach rapidly through sandy soil into groundwater. Aquatic:
If released to surface water, its primary loss will be by evaporation. The half-life for
evaporation will depend on wind and mixing conditions and was of the order of
hours in the laboratory. However, a modeling study using the EXAMS model for a
eutrophic lake gave a half-life of 10 days. Atmospheric: Will degrade by reaction
with hydroxyl radicals formed photochemically in the atmosphere. Half-life over
one month.
Physical: Not expected to biodegrade or bioconcentrate.
Other: For more information, see HANDBOOK OF ENVIRONMENTAL FATE AND
EXPOSURE DATA.

SECTION 13—DISPOSAL CONSIDERATIONS

Chemical waste generators must determine whether a discarded chemical is classified

as a hazardous waste. U.S. EPA guidelines for the classification determination are
listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and
local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS #107-06-2: waste number U077.

SECTION 14—TRANSPORT INFORMATION

US DOT IATA RID/ADR IMO Canada TDG

Shipping Name: ETHYLENE No information
DICHLORIDE available.
Hazard Class: 3
UN Number: UN1184
Packing Group: II

SECTION 15—REGULATORY INFORMATION

U.S. FEDERAL
TSCA
CAS #107-06-2 is listed on the TSCA inventory.
APPENDIX I MATERIAL SAFETY DATA SHEET I-7

Health & Safety Reporting List

CAS #107-06-2: Effective Date: 6/1/87; Sunset Date: 6/1/97
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS #107-06-2: 100 lb final RQ; 45.4 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS #107-06-2: acute, chronic, flammable.
Section 313
This material contains 1,2-Dichloroethane (CAS #107-06-2, 99 9%),which is subject
to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS #107-06-2 is listed as a hazardous air pollutant (HAP). This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2
Ozone depletors.
Clean Water Act:
CAS #107-06-2 is listed as a Hazardous Substance under the CWA. CAS #107-06-2
is listed as a Priority Pollutant under the Clean Water Act. CAS #107-06-2 is listed as a
Toxic Pollutant under the Clean Water Act.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS #107-06-2 can be found on the following state right to know lists: California,
New Jersey, Pennsylvania, Minnesota, Massachusetts.
The following statement(s) is (are) made in order to comply with the California
Safe Drinking Water Act: WARNING: This product contains 1,2-Dichloroethane, a
chemical known to the state of California to cause cancer. California No Significant
Risk Level: CAS #107-06-2: 10 mg/day NSRL
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
TF
Risk Phrases:
R 11 Highly flammable.
R 22 Harmful if swallowed.
R 36/37/38 Irritating to eyes, respiratory system and skin.
I-8 APPENDIX I MATERIAL SAFETY DATA SHEET

R 45 May cause cancer.

Safety Phrases:
S 45 In case of accident or if you feel unwell, seek medical advice immediately (show
the label where possible).
S 53 Avoid exposure—obtain special instructions before use.
WGK (Water Danger/Protection)
CAS #107-06-2: 3
Canada—DSL/NDSL
CAS #107-06-2 is listed on Canada’s DSL List.
Canada—WHMIS
This product has a WHMIS classification of B2, D2A, D2B.
Canadian Ingredient Disclosure List
CAS #107-06-2 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS #107-06-2: OEL-ARAB Republic of Egypt: TWA 5 ppm (2 mg/m3) OEL-
AUSTRALIA:TWA 10 ppm (40 mg/m3) OEL-AUSTRIA:TWA 20 ppm (80 mg/m3)
OEL-BELGIUM:TWA 10 ppm (40 mg/m3) OEL-DENMARK:TWA 1 ppm (4 mg/m3);
Skin OEL-FINLAND:TWA 10 ppm (40 mg/m3); STEL 20 ppm (80 mg/m3); CAR OEL-
FRANCE:TWA 10 ppm (40 mg/m3) OEL-GERMANY; Carcinogen OEL-HUNGARY:
STEL 4 mg/m3; Carcinogen OEL-JAPAN:TWA 10 ppm (40 mg/m3) OEL-THE
NETHERLANDS:TWA 50 ppm (200 mg/m3) OEL-THE PHILIPPINES:TWA 50 ppm
(200 mg/m3) OEL-RUSSIA:TWA 10 ppm OEL-SWEDEN:TWA 1 ppm (4 mg/m3);
STEL 5 ppm (20 mg/m3); Skin; CAR OEL-SWITZERLAND:TWA 10 ppm (40 mg/m3);
STEL 20 ppm (80 mg/m3) OEL-TURKEY:TWA 50 ppm (200 mg/m3) OEL-UNITED
KINGDOM:TWA 10 ppm (40 mg/m3); STEL 15 ppm (60 mg/m3) OEL IN BULGARIA,
COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND,
SINGAPORE, VIETNAM check A CGI TLV

SECTION 16—ADDITIONAL INFORMATION

MSDS Creation Date: 10/19/1998

Revision #6 Date: 4/17/2002
The information above is believed to be accurate and represents the best information
currently available to us. However, we make no warranty of merchantability or any
other warranty, express or implied, with respect to such information, and we assume
no liability resulting from its use. Users should make their own investigations to
determine the suitability of the information for their particular purposes. In no event
shall Fisher be liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential, or exemplary damages,
howsoever arising, even if Fisher has been advised of the possibility of such damages.