Electrocardiogram
Dr. Yasser El-Wazir
Professor of Medical Physiology
Learning outcomes
By the end of this lecture, student will be able to:
• Explain the ECG wave form generation
• Recognize the different ECG waves, segments and
intervals
• Identify the conventional 12 leads ECG
• Explain examples of ECG applications
Reference
Guyton & Hall Textbook of Medical Physiology
13th edition (2016):
• Chapter 11: The Normal ECG. Pages 133-136
Cardiac dipole generated during
depolarization & repolarization
During active depolarization &
repolarizations phases, parts
of outer surface of the cardiac
muscle has different polarities.
This creates a dipole which
drives current flow.
When the cardiac muscle is
completely depolarized or
completely repolarized, there
will be no potential difference
and current flow
Surface recording of cardiac
electric activity
It is possible to record the
cardiac electrical activity
via electrodes placed on
the body surface because
the body acts as a
conductor of the electrical
currents generated by the
heart.
ECG waves reflect sequential
cardiac electrical activity
9
ECG waves, segments & intervals
Temporal Relationship between
Cardiac AP and Surface ECG
ECG Leads
ECG paper
Small 0.04 second 0.2 second Big square
square
The standard paper speed is 25 mm/second; thus, the duration of the large
square is 0.2 second & the small square is 0.04 second
Limb Leads
Bipolar
• I : LA - RA
• II : LL - RA
• III : LL - LA
Unipolar
• aVR: RA - V
• aVL: LA - V
• aVF: LF - V
Orientation of the Limb Leads in
the frontal plane
Orientation of the chest (precordial)
leads in the horizontal plane
4th
5th
EXAMPLES OF ECG APPLICATIONS
Premature ventricular beats
AV junctional rhythm
Indiscernible P wave
Ventricular rhythm
Atrio-ventricular block
Abnormal delay in the AV node
First degree AV block
Prolonged PR interval > 0.2 second
Second degree AV block
The AV node allows every other
sinus beat to pass to the
ventricles
Third degree AV block
Third degree AV block
Regions of the Myocardium
Lateral
I, AVL,
V5-V6
Anterior /
Inferior Septal
II, III, aVF V1-V4
Acute antero-lateral infarction
Elevated ST segment in V2 – V5, LI, aVL
Acute inferior infarction
Elevated ST segment in II, III, aVF