SAFETY DATA SHEET
Refrigerant Gas R407C
1. Product and Company Identification
Product Name: Refrigerant Gas R407C
Distributor: National Refrigerants Ltd
4 Watling Close
Sketchley Meadows Business Park
Hinckley
Leicestershire
LE10 3EZ
Tel: +44(0)1455 630790
Fax: +44(0)1455 630791
Email: hexton@[Link]
Emergency Telephone Number: IN AN EMERGENCY DIAL +44(0)1865 407333
2. Hazard Identification
Colourless, volatile liquid with ethereal and faint sweet odour. Non-flammable material.
Overexposure may cause dizziness and loss of concentration. At higher levels CNS depression and
cardiac arrhythmia may result from exposure. Vapour displaces air and can cause asphyxiation
in confined spaces. At higher temperatures (>250oC) decomposition products may include
Hydrofluoric Acid (HF) and carbonyl halides.
Potential Health Hazard
Skin: Irritation would result from a defatting action on tissue. Liquid contact could cause frostbite.
Eyes: Liquid contact can cause sever irritation and frostbite. Mist may irritate.
Inhalation: When oxygen levels in air are reduced to 12 -14% by displacement, symptoms of
asphyxiation, loss of coordination, increased pulse rate and deeper respiration will occur. At high levels
cardiac arrhythmia may occur.
Ingestion: Ingestion is unlikely because of the boiling point of the material. Should it occur then
discomfort in the gastrointestinal tract from the rapid evaporation of the material, and the consequent
evolution of gas, would result.
3. Composition/Information on Ingredients
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Chemical Nature: Blend of halogenated alkanes
Component CAS No. Weight %
Difluoromethane (HFC32) 75-10-5 23
Pentafluoroethane (HFC125) 354-33-6 25
1,1,1,2-Tetrafluoroethane (HFC134a) 811-97-2 52
4. First Aid Measures
Skin: Promptly flush with water for at least 15 minutes. If there is evidence of frostbite, bathe (do not
rub) with lukewarm (not hot) water. If water is not available, cover with a clean, soft cloth or similar
covering. Get medical attention if symptoms persist.
Eyes: Immediately flush eyes with large amounts of water for at least 15 minutes (in case of frostbite
water should be lukewarm, not hot) lifting eyelids occasionally to facilitate irrigation. Get medical
attention.
Inhalation: Immediately remove to fresh air. If breathing has stopped, give artificial respiration. Use
oxygen as required, provided a qualified operator is available. Get medical attention. Do not give
epinephrine (adrenaline).
Ingestion: Ingestion is unlikely because of the physical properties of the material, and is not expected to
be hazardous. Do not induce vomiting unless instructed to do so by a physician.
Advice to Physician: Because of the possible disturbance of cardiac rhythm, catecholamine drugs, such
as epinephrine, should be used with special caution and only in situations of emergency life support.
Treatment of overexposure should be directed at the control of symptoms and the clinical conditions.
5. Fire Fighting Measures
Extinguishing Media: All extinguishing agents are suitable. Use any standard agent – chose the most
appropriate for type of surrounding fire (the material itself is not flammable).
Specific Hazard: Pressurised container. On heating there is a risk of bursting due to internal pressure
build-up. At high temperatures thermal decomposition gives toxic vapours – Hydrofluoric Acid (HF)
and carbon oxides.
Specific fire fighting methods: Stay upwind. Evacuate the personnel away from the fumes. Cool down
the containers/equipment exposed to heat with water spray.
Protection of the fire fighters: Wear a self-contained breathing apparatus and a protective suit.
6. Accidental Release Measures
Personal Precautions: Avoid contact with skin and eyes. Do not breathe the gas. No naked flames. DO
NOT smoke. Wear personal protective equipment (see Section 8, “Exposure controls/ personal
protection).
Vapour is heavier than air. Shut off low-level openings in the vicinity (ventilation shafts, drains etc.).
Prevent the product from entering cellars, basements since the vapour may create a suffocating
atmosphere. Stop the leak. Ventilate the spillage area. Ventilate enclosed areas, basements, pits etc.
7. Handling and Storage
Handling: Avoid breathing the vapour. Avoid liquid contact with the eyes, skin or clothing. Do not
puncture or drop the cylinders. Do not expose them to open flame or excessive heat. Follow standard
precautions for handling and use of compressed gas cylinders.
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Storage: Store in a cool, well-ventilated area of low fire risk and out of sunlight. Protect cylinders and
fittings from physical damage. Storage in subsurface locations should be avoided. Close valve tightly
after use and when empty.
Technical Measures: The vapour is heavier that air. Storage area should be equipped with low-level
ventilation. High concentrations may be produced at low levels where general ventilation is poor. In
such cases provide adequate ventilation or wear suitable respiratory equipment with positive air supply.
For correct refrigerant composition system should be charged using the liquid phase not vapour phase.
Liquid refrigerant transfers between containers and to and from system can result in static charge
generation. Ensure adequate earthing.
Packaging Material: Recommended: Steel
To be Avoided: Alloys containing more that 2% magnesium.
Plastic materials.
8. Exposure Controls & Personal Protection
Engineering Control: Provide local ventilation at filling zones and areas where leakage is probable.
Mechanical (general) ventilation may be adequate for other operating and storage areas.
Personal Protective Equipment
Skin Protection: Skin contact with refrigerant may cause frostbite. General work clothing and gloves
(leather) should provide adequate protection. If prolonged contact with the liquid or gas is anticipated,
insulated gloves constructed of PVA, neoprene or butyl rubber should be used. Any contaminated
clothing should be promptly removed and washed before reuse.
Eye Protection: For normal conditions wear safety glasses. Where there is a reasonable probability of
liquid contact wear chemical safety goggles.
Respiratory Protection: None generally required for adequately ventilated work situations. For
accidental release or non-ventilated situations, or release in confined space, where the concentration is
above 1000 ppm use self contained approved breathing apparatus or suitable respirator.
Additional Recommendations: Where contact with liquid is likely, such as in a spill or leak,
impervious boots and clothing should be worn. High dose-level warning signs are recommended for
areas of principal exposure. Provide eyewash stations and quick drench shower facilities at convenient
locations. For tank cleaning operations ventilate the tank and do gas entry tests before entering. Follow
working in confined spaces regulations.
Occupational Exposure Limits:
Component LTEL
Difluoromethane Not Available
1,1,1-Trifluoroethane Not Available
1,1,1,2-Tetrafluoroethane 1000 ppm (4240 mg/m3)
9. Physical and Chemical Properties
Appearance: Clear, colourless liquid and vapour.
Physical State: Gas at ambient pressure and temperature.
Chemical Formula: Difluoromethane CH2F2
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1,1,1-Trifluoroethane CF3-CH3
1,1,1,2-Tetrafluoroethane CF3-CHF2
Odour: Faint ethereal odour.
Density: 1.16 at 21oC (70oF)
pH Neutral
Boiling Point: -43oC
Freezing Point: Not Determined
Vapour Pressure: 10.63 Bar at 21oC (70oF)
24.27 Bar at 54oF (130oF)
Vapour Density (Air =1.0) 3.0
10. Stability and Reactivity
Stability: Stable at ambient temperature and under normal conditions of use.
Hazardous Reactions: May decompose on contact with hot surfaces and flames. Incompatible with
alkali metals, finely divided metals, magnesium and alloys containing more than 2% magnesium. Can
react violently if in contact with alkali metals, alkaline earth metals, sodium, potassium and barium.
Hazardous decomposition products: On contact with very hot surfaces, or flames, thermal
decomposition (Pyrolysis) releases toxic gasses (hydrofluoric acid and possibly carbonyl halides).
11. Toxicological Information
Immediate (Acute) Effects:
HFC32: LC50: 4 hr (rat) >520 000 ppm/ Cardiac Sensitisation threshold (dog) >350 000 ppm
HFC125: LC50: 4 hr (rat) >800 000 ppm/ Cardiac Sensitisation threshold (dog) 75 000 ppm
HFC134a: LC50: 4 hr (rat) >500 000 ppm/Cardiac Sensitisation threshold (dog) >80 000ppm
Delayed (Sub-chronic & Chronic) Effects
HFC125: Teratogenic NOEL (rat & rabbit) 50 000 ppm
Sub-chronic Inhalation NOEL (rat) ≥ 50 000 ppm
Chronic NOEL 10 000 ppm
HFC32: Teratogenic NOEL (rat & rabbit) 50 000 ppm
Sub-chronic Inhalation NOEL (rat) 50 000 ppm
HFC134a: Teratogenic NOEL (rat & rabbit) 40 000 ppm
Sub-chronic inhalation NOEL (rat) 50 000 ppm
Chronic NOEL 10 000 ppm
12. Ecological Information
Global Warming Potential: 1653 (CO2 = 1)
Ozone Depletion Potential: 0.0 (R11 = 1)
13. Disposal Considerations
Prohibition: Do not allow the product to be released to the environment.
Destruction/Disposal: Consult the manufacturer or supplier for information regarding recovery and
recycling of the product. If recovery is not possible incinerate at a licensed installation.
Contaminated Packaging:
Decontamination/Cleaning: Degas.
Destruction/Cleaning: Reusable containers to be returned to the supplier. Non-reusable (Disposable)
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containers to be disposed of as hazardous waste at an approved hazardous or special waste collection
point or returned to the supplier for disposal.
14. Transport Information
Air Transport (ICAO/IATA)
UN No.: 3340
Class: 2.2
Proper Shipping Name: Refrigerant Gas R407C
Sea Transport (IMDG)
UN No. 3340
Class: 2.2
Marine Pollutant: Not classified as Marine Pollutant
Proper Shipping Name: Refrigerant Gas R407C
EmS F-C, S-V
Road Transport (ADR)
UN No. 3340
Class: 2
Classification Code: 2A
Hazard Identification No. 20
Proper Shipping Name: Refrigerant Gas R407C
15. Regulatory Information
Risk Phrases: No risk phrases.
Safety Phrases:
S47: Keep at temperature not exceeding 45oC.
S41: In case of fire and/or explosion do not breathe fumes.
S24/25: Avoid contact with skin and eyes.
United Kingdom: Handle in accordance with relevant British Legislation e.g. Health and Safety at
Work Act 1974, Environment Protection Act 1990, EU Directive 2006/4/E, UE Regulation 842/2006 (F
Gas Regulations).
Note: The regulatory information given above only indicates the principal regulations specifically
applicable to the product described in the Safety Data Sheet. The user’s attention is drawn to the
possible existence of additional provisions, which complete these regulations. Refer to all applicable
National, International and Local regulations or provisions.
16. Other Information
Uses: Refrigerant.
National Refrigerants Ltd. believes that the information and recommendations contained herein
(including data and statements) are accurate as of the date hereof. NO WARRANTY OF FITNESS FOR
ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY, OR ANY OTHER WARRANTY,
EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED HEREIN. The
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information provided herein relates only to the specific product designated and may not be valid where
such product is used in combination with any other methods of use of the product and of the information
referred to herein are beyond the control of National Refrigerants Ltd. National Refrigerants of America
expressly disclaims any and all liability as to any results obtained or arising from any use of the product
or reliance on such information.
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