Textbook Discussion
(Dengue Fever)
Dengue virus is transmitted by female mosquitoes mainly of the species ‘Aedes aegypti’ and, to a
lesser extent. These mosquitoes are also vectors of chikungunya, yellow fever and Zika viruses.
Dengue is widespread throughout the tropics, with local variations in risk influenced by rainfall,
temperature, relative humidity and unplanned rapid urbanization.
Dengue causes a wide spectrum of disease. This can range from subclinical disease (people may
not know they are even infected) to severe flu-like symptoms in those infected. Although less
common, some people develop severe dengue, which can be any number of complications
associated with severe bleeding, organ impairment and/or plasma leakage. Severe dengue has a
higher risk of death when not managed appropriately. Severe dengue was first recognized in the
1950s during dengue epidemics in the Philippines and Thailand. Today, severe dengue affects
most Asian and Latin American countries and has become a leading cause of hospitalization and
death among children and adults in these regions.
Symptoms of Dengue Fever
Symptoms, which usually begin four to six days after infection and last for up to 10 days, may
include
Sudden, high fever
Severe headaches
Pain behind the eyes
Severe joint and muscle pain
Fatigue
Nausea
Vomiting
Skin rash, which appears two to five days after the onset of fever
Mild bleeding (such a nose bleed, bleeding gums, or easy bruising)
Incubation Period
Dengue is a severe, flu-like illness that affects infants, young children and adults, but seldom
causes death. Symptoms usually last for 2–7 days, after an incubation period of 4–10 days after
the bite from an infected mosquito.
Risk Factors?
The risk factors for dengue fever are as follows:
Traveling to or living in endemic or outbreak areas, especially if no mosquito control is
attempted by the people or government in subtropical areas
Mosquito bites by Aedes aegypti
A repeated infection with another serovar of dengue virus with antibodies in the serum
active against the first infecting virus type
Not taking precautions to avoid Aedes mosquitoes
Treatment
Fortunately, this viral disease is usually self-limited and usually adequate hydration and pain
control will help the person through the infection. Nonsteroidal anti-inflammatory agents (for
example, aspirin (Bayer, Ecotrin), ibuprofen (Motrin), and other NSAIDs) should be avoided
because of the tendency of the dengue viruses to cause hemorrhages.