MEDICATION: VALPORIC ACID CONCEPT: Psychiatric Nursing
CATEGORY CLASS: Anticonvulsant
PURPOSE OF MEDICATION
Expected Pharmacologic Action: Therapeutic Use:
Work by calming the hyperactivity of the brain during mania.
Facilitates the effects of the inhibitory neurotransmitter GABA in the
brain.
Medication Administration: (Route, Dose Frequency)
Side Effects and Adverse Effects:
Route: Oral/ By Mouth Dosage: 250 mg, BID
Nausea, Dizziness, Drowsiness, Hepatotoxicity, Insomnia, emotional upset, tachycardia,
palpitations, hemorrhage, thrombocytopenia, bruises, photosensitivity reaction.
Nursing Interventions:
Contraindications:
-Monitor platelet count every 3-6 months.
Mitochondrial disorder
-Monitor liver function test every 3-6 months
-Obtain ECG since the patient may experience tachycardia
-Provide safety measure for the patient (side rails up)
-Do not administer the medication during night time.
Precautions: -Assess the mental status of the patient.
Patient with allergy to drug, patient with hepatic disease
Client Education:
Interactions: -Tell the patient to take the drug with food to prevent GI irritation
DRUG TO DRUG: Aspirin: may cause valproic acid toxicity. -Instruct the patient to avoid chewing of the medication
Carbamazepine: May decrease valproic acid level Lamotrigine: May
decrease valproic acid level -Instruct the patient to use sunscreen to protect the skin from sunlight.
DRUG TO LIFESTYLE: Alcohol drinker: may cause excessive CNS -Instruct the patient to avoid having wounds or cut or to bump in hard
depression
objects.
Evaluation of Medication Effectiveness: -Encourage the patient to verbalize feelings.
Decrease the manic episode of a patient by increasing the GABA -Instruct the patient to avoid driving and other potentially hazardous
neurotransmitters in the brain
activities