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Actos Drug Study

Pioglitazone is a thiazolidinedione taken orally once daily to treat type 2 diabetes as an adjunct to diet. It works by increasing insulin sensitivity and decreasing hepatic glucose output. Common side effects include edema, headache, upper respiratory infections, and hypoglycemia when taken with other antidiabetics. Nurses should monitor patients for signs of congestive heart failure, liver problems, hypoglycemia, and weight gain while on pioglitazone.
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0% found this document useful (0 votes)
804 views2 pages

Actos Drug Study

Pioglitazone is a thiazolidinedione taken orally once daily to treat type 2 diabetes as an adjunct to diet. It works by increasing insulin sensitivity and decreasing hepatic glucose output. Common side effects include edema, headache, upper respiratory infections, and hypoglycemia when taken with other antidiabetics. Nurses should monitor patients for signs of congestive heart failure, liver problems, hypoglycemia, and weight gain while on pioglitazone.
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
  • Drug Information Table: This table provides detailed information about various drugs, covering aspects such as dosage, indication, communication points, and adverse effects.

Name of drug Dosage, Route, Indication Contraindication Mechanism of Drug-to-drug Adverse effects Nursing

and Frequency action interaction responsibilities


Generic name PO 15–30 mg Adjunct to diet in Hypersensitivity Results in insulin Pioglitazone may Body as a Whole: BEFORE
Pioglitazone once daily (max: the treatment of to pioglitazone, sensitivity by decrease serum Headache, >Monitor signs
Hydrochloride 45 mg q.d.) type 2 diabetes troglitazone, affecting insulin levels for oral myalgia, edema. and symptoms of
mellitus. rosiglitazone, receptors. contraceptives; CV: Edema, fluid hypoglycemia
Brand name: englitazone; type Decreases ketoconazole retention,
Actos 1 diabetes, or hepatic glucose may increase exacerbation of >Monitor closely
treatment of DKA; output and serum levels of heart failure. GI: for signs and
Therapeutic active liver increases insulin- pioglitazone. Tooth disorder. symptoms of CHF
classification: disease or ALT dependent Ginseng may Respiratory: or exacerbation of
Hormones and levels >2.5 times muscle glucose potentiate Upper respiratory symptoms with
synthetic normal limit; uptake in skeletal hypoglycemic tract infection, preexisting CHF.
substitutes; pregnancy muscle and effects sinusitis,
antidiabetic; (category C), adipose tissue. pharyngitis. >Monitor weight
thiazolidinedione lactation. Metabolic: and notify
Hypoglycemia, physician of
mild anemia. development of
edema.

DURING
>Discontinue
drug if ALT >3
times ULN or
patient has
jaundice

>Use or all barrier


contraceptive if
using hormonal
contraception

>May need
adjustment for
other antidiabetic
drugs to avoid
hypoglycemia

AFTER
>Emphasize the
importance of
adhering to
nutritional
guidelines and
the need for
periodic
assessment of
glycemic levels.

>Educate patient
about symptoms
of hyperglycemia

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