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Norpramin: A Guide for Healthcare Professionals

Desipramine (Norpramin) is a tricyclic antidepressant medication categorized as pregnancy category C, meaning it should only be used during pregnancy if the potential benefits outweigh the risks. It is distributed in breast milk, so breastfeeding is not recommended while taking desipramine due to unknown effects on nursing infants. Pregnancy categories A through D are defined based on available evidence from animal and human studies regarding fetal risk, with category A generally being acceptable and category D only used in life-threatening emergencies when safer alternatives are unavailable.

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39 views1 page

Norpramin: A Guide for Healthcare Professionals

Desipramine (Norpramin) is a tricyclic antidepressant medication categorized as pregnancy category C, meaning it should only be used during pregnancy if the potential benefits outweigh the risks. It is distributed in breast milk, so breastfeeding is not recommended while taking desipramine due to unknown effects on nursing infants. Pregnancy categories A through D are defined based on available evidence from animal and human studies regarding fetal risk, with category A generally being acceptable and category D only used in life-threatening emergencies when safer alternatives are unavailable.

Uploaded by

William Omar
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

1/10/2019 Norpramin (desipramine) dosing, indications, interactions, adverse effects, and more

This site is intended for healthcare professionals

desipramine (Rx)
Brand and Other Names: Norpramin
Classes: Antidepressants, TCAs

Pregnancy & Lactation


Pregnancy Category: C

Lactation: distributed in breast milk, do not nurse (AAP states effect on nursing infants is unknown
but may be of concern)

Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or
animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not
available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of


human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

[Link] 1/1

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