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Pharmacology Quick Reference Guide

This document provides information on the mechanisms of action, common uses, and characteristics of various medications and diseases. It discusses the modes of action of medications such as montelukast, ranitidine, tetracycline, doxycycline, antihistamines, ibuprofen, aspirin, clopidogrel, antidepressants, warfarin, heparin, and others. It also lists the most common medications used for conditions like allergies, asthma, pregnancy, infections, seizures, and more. Finally, it outlines characteristics of common diseases including periodontitis, seizures, heart conditions, cleft palate, thyroid issues, cancers, and genetic syndromes.
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100% found this document useful (1 vote)
286 views15 pages

Pharmacology Quick Reference Guide

This document provides information on the mechanisms of action, common uses, and characteristics of various medications and diseases. It discusses the modes of action of medications such as montelukast, ranitidine, tetracycline, doxycycline, antihistamines, ibuprofen, aspirin, clopidogrel, antidepressants, warfarin, heparin, and others. It also lists the most common medications used for conditions like allergies, asthma, pregnancy, infections, seizures, and more. Finally, it outlines characteristics of common diseases including periodontitis, seizures, heart conditions, cleft palate, thyroid issues, cancers, and genetic syndromes.
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Dr.

PC 1

Speedo Snail: Quick Review

Drugs: Mode/Mechanism of Action


➢ MOA of Montelukast: Inhibition of leukotrienes (Used for Asthma and seasonal allergies)
➢ MOA of Ranitidine: Reduce gastric secretion
➢ MOA of Tetracycline: Bacteriostatic
➢ MOA of Doxycycline: inhibit 30s ribosome/inhibit collagenous
➢ MOA of H-antagonist (Antihistamine): Blocking histamine at the receptor
➢ MOA of Ibuprofen: Reversible
➢ MOA of Aspirin: Irreversibly inhibit platelet aggregation, inhibit platelet cyclooxygenase by
blocking the formation of Thromboxane A2.
➢ MOA of Clopidogrel (Plavix): Alter platelet function, inhibit platelet aggregation irreversibly (Give
pt allergic to Aspirin, no ulcer side effect, given to pt with past ulcer history)
➢ MOA of Anti-depressant drug:
➢ MOA of Warfarin: Inhibit vitamin K reductase resulting in depletion of reduced form of vit K,
Decrease K+ needed to synthesize factors II, VII, IX, X
➢ MOA of Heparin: Anti-coagulant reversibly to anti-thrombin II & prevent conversion of
fibrinogen to fibrin
➢ MOA of Dicoumarol: Anti-coagulant that inhibits vitamin K reductase & affects K-dependent
coagulation factors (Tx: Coronary Infarct/MI)

➢ MOA Benzodiazepines: modulate activity of inhibitory NT (GABA) at the GABA receptor
➢ MOA of Xanax:
➢ Morphine relieves pain by: Acting on opioid mu receptor on neural cell membrane
➢ MOA of Anticholinergic: inhibit binding of acetylcholine to muscarinic and nicotinic receptors
(found in eyes, secretory glands, nerve endings to smooth muscle cells)
➢ MOA of Acetaminophen: Antipyretic effect by acting on centers in hypothalamus
➢ MOA of Levodopa: Replenish deficiency of dopamine in patients with Parkinson’s
➢ MOA of Reserpine: stabilize the axon terminal membrane preventing release norepinephrine
(Used for HTN)
➢ MOA of Naloxone: Non-selective and competitive opioid receptor antagonist in case of opioid
overdose
➢ MOA of Clonidine: Centrally acting sympatholytic (alpha adrenoceptor agonist)
➢ MOA of Zoloft: Sertraline – Selective serotonin reuptake inhibitors
➢ MOA of Sulfonylurea: Increased insulin production and sensitivity by Beta cells stimulation by
binding to ATP dependent K channel/ Stimulation of pancreatic beta cells to secrete insulin.
➢ MOA of Sulfonamides: Inhibit folic acid suynthesis
➢ MOA of Periostat: Inhibit collagenase/protein synthesis
➢ MOA of Doxycycline: Inhibits MMP (Matrix Metalloproteases)
➢ MOA of Bisphosphonate: Inhibit the Osteoclast via apoptosis

Best of luck to All


Dr. PC 2

Most Common Medication Used


➢ Allergic to Aspirin: Take Acetaminophen, not Ibuprofen
➢ Asthmatic pt: Used Acetaminophen (Tylenol), Avoid using Aspirin, can cause Hyperventilation
➢ Pregnant Women: Use Acetaminophen, No NSAIDs
➢ Antibiotic used in gingival cervical fluid for periodontal bacteria: Doxycycline
➢ HIV related oropharyngeal candidiasis: Systemic Fluconazole
➢ Antifungal for TROCHES: Clotrimazole
➢ Most common medicine for Grand mal: Dilantin
➢ Ethosuximide is most commonly used: Absence epilepsy (Petit mal)
➢ Contraindication with ginseng: Aspirin
➢ Meds used for Benzodiazepine reversal: Flumazenil
➢ Opioid antagonist: Naloxone (sign of opioid toxicity: give Naloxone)
• Morphine overdose tx: Naloxone
➢ Detoxification of Morphine addiction: Methadone
➢ Mixed agonist-antagonist analgesics: Pentazocine, Nalbuphine
➢ Use for sedation on child: Secobarbital/Pentobarbital (Don’t use Meperidine)
➢ Antibiotic for non-odontogenic maxillary sinusitis: Augmentin (Amoxicillin + clavulanic acid)
➢ Acute ulcerative periodontitis with lymphadenopathy: Metronidazole
➢ Antibiotic for mycoplasma: Erythromycin
➢ Med for Trigeminal Neuralgia: Anticonvulsive drug
➢ Child Used Amphetamine med: ADHD (if kid takes, tell him not to take prior dental
appointment)
➢ Tx for xerostomia with Sjogren’s syndrome: Cevimeline HCL
➢ Medication for:
• Grand mal seizure: Phenytoin
• Petit mal seizure: Ethosuximide & Valproic acid
• Status epilepticus: Diazepam, lorazepam, midazolam (mostly prefer)
(benzodiazepine)
➢ Coronary infarct: Dicumarol (Vit K antagonist)
➢ Antidote of Warfarin: Vit K
➢ Antidote of Heparin: Protamine sulfate
➢ The most potent & most toxic LA: Dibucaine
➢ Long acting LA with less toxic: Bupivacaine
➢ Pain medication for liver toxicity & renal toxicity: Oxycodone
➢ Tx of Myasthenia gravis: Physostigmine & Pyridostigmine
➢ Tricyclic Antidepressant: Imipramine & amitriptyline
➢ Best initial tx for TMJ muscle spasm: NSAIDS + Muscle relaxant
➢ Tx for Rheumatic arthritis: Adalimumab & infliximab (bind to TNF – alpha receptors)
➢ Percocet is class II schedule drug (Oxycodone + Acetaminophen)
➢ Motion sickness: Scopolamine, Diphenhydramine (Benadryl)
➢ Drug choice for pt with bradycardia: Atropine
➢ Asthma: Albuterol (short acting) and theophylline (long acting)
➢ Amantadine antiviral drug used for: Influenza A & Parkinson Disease

Best of luck to All


Dr. PC 3

➢ Epi to reverse give: Prazosin or chlorpromazine


➢ Best drug to reverse effect of Benzodiazepine: Flumazenil (benzodiazepine antagonist)
➢ Best drug to reverse effect of Midazolam (Versed): Flumazenil
➢ Serotonin syndrome: Tramadol (narcotic pain killer like morphine) + SSRI
➢ Tx of Parkinson disease: Carbidopa + Levodopa
➢ Pt with sleep apnea, which pain med should give: Ibuprofen/acetaminophen
➢ Tx of Trigeminal neuralgia: Carbamazepine
➢ Tx of Grand mal seizure (febrile) (most common in child): Phenytoin (Dilantin)
➢ Tx of Status Epilepticus: Valium (Diazepam)
➢ Tx of Petit mal (absence) seizure: Ethosuximide
➢ Tx of lidocaine induced seizure: Diazepam
➢ Tx of Depression & Anxiety for Obsessive Compulsive Disorder: Xanax (Alprazolam)
➢ Best benzodiazepine for pt with liver cirrhosis: LOT (Lorazepam, Oxazepam, Temazepam) due to
not metabolized by liver, so safe for to induce liver failure.
➢ Best benzo for IV sedation: Midazolam
➢ Pt allergic to ester & amides: Use Diphenhydramine (Benadryl)
➢ Laryngospasm: Tx with Pure oxygen, if persistent use Succinylcholine, if severe then
cricothyroidism
➢ Malignant Hyperthermia: tx with Dantrolene
➢ ADHD Kid: Ritalin (methylphenidate hydrochloride)
➢ For Hirsutism: Eflornithine
➢ Adrenal Crisis: Cardiac shock, hypotension, CV collapse, 100mg 0.9% hydrocortisone with saline
➢ Adrenal insufficiency: caused by prolonged regimen of Corticosteroids, more than 2 years
➢ Thyroid Crisis: Hypertension and Increased HR
➢ Anti-anxiety in pregnant women: Promethazine

Most Common Diseases Features/Characteristics


➢ Chronic Periodontitis, Most common in Black males
➢ Most common medical emergency in dental setting: Syncope
➢ Most common seizure in kids: Febrile
➢ Most common heart condition in child: Ventricular septal defects
➢ Commonly affected with Primary Herpetic Gingivostomatitis: Age 4
➢ FAS syndrome: mid face discrepancy
➢ Most common abnormality among the following: Cleft lip & palate (Dentinogenesis imperfecta,
Amelogenesis imperfecta, Dentinal dysplasia)
➢ Combination Syndrome: increased Vertical Dimension
➢ Thyroid crisis symptoms: tachycardia
➢ Acantholysis seen: Pemphigus
➢ Most commonly associated with dysplastic cells/dysplasia: Erythroplakia
➢ Histologically, Most closely resembles normal parotid gland: Pleomorphic adenoma
➢ Most commonly associated with osteogenesis imperfecta: Dentino-genesis imperfecta
➢ Most common between Crohn’s, Peutz-Jeghers & Gardner’s syndrome: Intestinal polyps

Best of luck to All


Dr. PC 4

➢ Gardner’s syndrome (Familial adenomas polyposis): multiple osteomas, odontoma, intestinal


polyps
➢ Peutz-Jeghers syndrome: multiple melanotic macules or pigmentation, GI polyps
➢ OKC is most commonly associated with: Nevoid basal cell Carcinoma
➢ Most common site for sialolithiasis: Submandibular gland, common duct: Wharton’s duct
➢ Warthin tumor (Papillary Cystadenoma-lymphomatosum) most common: parotid gland
➢ Most common deep fungal disease in USA: Candidiasis
➢ Perineural invasion seen: Adenoid cystic carcinoma
➢ Common features of Cleidocranial dysplasia: Delayed eruption, supernumerary teeth
➢ Peutz Jeghers syndrome: Pigmentation of face, lips, and oral cavity and intestinal polyps
➢ Treacher Choline syndrome (Mandibulofacial dysostosis): relation to Zygoma
➢ Cleidocranial dysplasia: relation to clavicle
➢ Brown tumor (Central giant cell granuloma) is associated with: Hyperparathyroidism
➢ Most common location of oral cancer in USA: Tongue
➢ Pemphigus: Suprabasilar vesicles and acantholysis
➢ Pemphigoid: Subepidermal and NO acantholysis
➢ Papillon Lefevre Syndrome: Hyperkeratosis of palms & soles of feet, premature tooth loss,
periodontitis
➢ Crouzon syndrome: Beaten metal appearance of the skull. Hypertelorism (Increased interpupil
distance), midface deficiency, cranial bones fuse too soon
➢ Steven Johnson syndrome: Disease of skin & mucous membrane, begins with flue like
symptoms, top skin layer dies & sheds off, burning eyes
➢ McCune Albright syndrome (Polycystic fibrous dysplasia): Café Au lait spots, Coast of Marine like
border is seen in pigmented lesion
➢ Neurofibromatosis: Café au lait, Liche nodule of Iris
➢ Pulmer Vinson syndrome: atrophy of gastric and pharyngeal mucosa, spoon nails (Koilonycias)
(predisposal to oral carcinoma in postmenopausal females)
➢ Frey’s syndrome: Gustatory sweating while eating and crocodile tears
➢ Melkersson Rosenthal syndrome: Facial paralysis, cheilitis granulomatosis, scrotal tongue
➢ Lupus erythematosus affects in: heart, renal
➢ Bechet’s disease ulcer resembles to: Aphthous ulcer
➢ Scleroderma: Mona-Lisa face, Widening PDL, deposition of collagen in organs lead organ failure,
loss of mandibular ramus.
➢ CREST syndrome: Limited Scleroderma, only in lower arms & Legs, sometimes face & throat.
➢ Ectodermal dysplasia: sparse hair, anodontia (partial/complete), oligodontia, hypodontia,
Hypohydrotic
➢ Max Nitrous oxide in kid: 30%
➢ Most common location of SCC (most common oral cancer): Posterior lateral border of tongue
➢ Uncontrolled diabetes inhibits osteoblastic activity
➢ Most common site of Basal cell carcinoma: Middle third of the face
➢ Most common: Cleft lip in male, cleft palate in female
➢ Multiple myeloma: Bence jones protein, punched out lesion, plasma cell infiltrate, skeletal
radiolucency (Bone pain is the 1st sign)
➢ Most common cyst in oral cavity: Peri-apical (radicular) cyst

Best of luck to All


Dr. PC 5

➢ Cyst has highest rate of recurrences: OKC


➢ Most common tumor of minor salivary gland: Adenoid cystic carcinoma
➢ Fibrous dysplasia: Ground glass appearance
➢ Most common non-odontogenic cyst: Nasopalatine duct cyst (X-ray: Heart shaped near central
incisor, tx: Enucleation)
➢ Nevoid basal cell carcinoma (Gorlin Syndrome): seen multiple OKCs and palmar pitting, planter
kerato-cyst, causes cyst in the Jaws
➢ Verrucous carcinoma: Cauliflower, warts caused by HPV (16 & 18)
➢ Most recurrence: OKC (associated with Gorlin syndrome) , Least recurrence: Adenoid
odontogenic tumor

Most Common in Teeth/Bone


➢ Most common impacted tooth: Max 3rd molar, Mandibular 3rd molar, , Maxillary Canine (NEED
PUT MOST to Least)
➢ Most common congenital missing teeth: 3rd molar, 2nd PMs, Maxillary lateral (NEED PUT MOST
to Least)
➢ Most common occlusion in primary teeth: Edge to Edge
➢ Most common facial fracture nasal bone fracture, 2nd most mandibular fracture
➢ Most likely crowded/blocked out of mandibular arch: 2nd PM
➢ Most likely crowded/blocked out of maxillary arch: Canine
➢ Most common reason of maxillary tori removal: Prosthetic treatment
➢ Found Presence of Supernumerary teeth in: Cleidocranial dysplasia
➢ Oligodontia mostly related to: Ectodermal dysplasia (mostly seen in Alveolar bone)
➢ Odontomas mostly associated with: Gardeners syndrome
➢ Most common teeth lost by perio problem: Max molars
➢ Most common tooth have caries: mand 1st molar, Least common: Mand incisors
➢ Most common complication of extraction: Root fracture
➢ Most perforation on max lateral root during RCT: Mesial
➢ Dens invaginates is commonly seen: Max lateral
➢ Caries in radiotherapy patient mostly in: Cervical
➢ Most common pattern of osseous defect in chronic periodontitis: Horizontal (Crater, if
horizontal is not an option)
➢ Most likely cause pulp necrosis after trauma to the tooth: Pulp hyperemia
➢ Most common mid face fracture: Zygomatico-maxillary
➢ Best allograft: FDBA cadaver
➢ Most common benign tumor in oral cavity: Fibroma
➢ Lesion of alveolar ridge in infant: Bohn’s nodule
➢ Dry socket is a form of Periostitis, Pathophysiology of dry socket: Fibrinolysis
➢ Intraoral dental sinus: Parulis (made up of granulation tissues, AKA gumboil)
➢ Dens-in-dente most common in: Max lateral
➢ Most common site of osteo-fibrosis (Cementoma): Mandibular Anterior
➢ Diagnosis of OKC: Histology
➢ Hypercementosis, most common in PMs in Paget’s disease

Best of luck to All


Dr. PC 6

➢ Discolored of teeth seen:


• Porphyria: purplish brown
• Cystic fibrosis: yellowish brown
• Erythroblastic fetalis: blue greenish
➢ Erythroblastosis fetalis: Ring like enamel hypoplasia
➢ Blue sclera is seen in: osteogenesis imperfecta, hypophosphatasia
➢ Actinomyces oral manifestation: Lumpy jaw, sulfur granules
➢ 1st sign of multiple myeloma: Bone pain (punched out lesion in X-ray)
➢ Osteosarcoma: Sun burst and uniform/symmetrical widening PDL, paresthesia
(numbness/tingling)

Disease with involved Bacteria/virus


➢ Primary bacteria for initiation of caries: Strep. Mutans
➢ Red Complex Bacteria: P. gingivalis, T. forsythia, T. denticola
➢ Oral hairy leukoplakia: EBV
➢ Condyloma Accuminata: HPV
➢ Koplik’s Spot: Rubella
➢ Ramsay Hunt Syndrome: caused by Herpes Zoster. Associated with shingles, facial nerve
damage, & loss of hearing in affected site

Contraindications
➢ Acetaminophen is contraindicated with Liver disease (cause hepatotoxicity) and alcohol
➢ Nitrous Oxide: 1st trimester only, nasal congestion
➢ Asthma, can participate with attack: Aspirin
➢ Epinephrine (Adrenalin) should NOT be used with tricyclic anti-depressant
➢ Epi is not used in: Hyperthyroidism
➢ Erythromycin and Tetracycline are prescribed carefully in patients with peptic ulcer because:
interact with Antacids
➢ Macrolides avoided in Asthma: interact with Theophylline
➢ Penicillin is cross allergenic with Cephalosporin because of Beta Lactamase
➢ Pilocarpine is not used in pt with G6PD deficiency
➢ Never give penicillin with tetracycline: due to Antagonists property
➢ Strongest glucocorticoids: Dexamethasone
➢ Benzodiazepine antagonist: Flumazenil
➢ Opioid antagonist: Naloxone
➢ Antihistamine is contraindicated with Erythromycin: Terfenadine
➢ Heparin is contraindicated to pt with taking gingko biloba
➢ In multiple sclerosis: LA with epi is contraindicated
➢ Lidocaine may show cross-allergy with: Mepivacaine
➢ Bisphosphonates are NOT used for: Multiple myeloma, Osteomyelitis
➢ Drugs caused gingival hyperplasia: Phenytoin, nifedipine, cyclosporine

Best of luck to All


Dr. PC 7

➢ Side effect of chloramphenicol: Aplastic anemia


➢ Aspirin is contraindicated with Coumadin
➢ Ginseng is contraindicated with Aspirin, Warfarin, NSAIDs
➢ Gingko biloba is contraindicated with Heparin
➢ Glucocorticoids are contraindicated in Diabetes
➢ Benzodiazepines (Diazepam) is contraindicated for pregnant women, myasthenia gravis, acute
narrow glaucoma, COPD, emphysema
➢ Meds cause Xerostomia:
• Diuretics
• CCBs
• Antihistamine
➢ Meds cause Gingival Hyperplasia:
• Phenytoin/Dilantin
• Nifedipine/Procardia (CCBs)
• Cyclosporine
➢ Meds cause Bad taste:
• Metronidazole
• Chantix
• Carbamazepine

Other Most Common


➢ Ketone Bodies: DM1/Hyperglycemia, most common complication of DM1: Blindness
(retinopathy)
➢ Most Common:
• Caries: white
• Treated caries: White
• Untreated caries: African American
• Periodontal disease: African American
• Caries in Kid: Hispanic
➢ Most dental financing: Self-pay
➢ Most radio resistant: Skeletal muscle
➢ Secondary hypertension: Renal failure
➢ Most harmful in implant: Horizontal force
➢ Vasovagal syncope, 1st sign: Hypotension
➢ Pseudomembranous colitis caused by clindamycin (effective against most anaerobes):
Overgrowth of C. diff
➢ Interleukin related with bone destruction: IL 1
➢ Lumpy jaw appearance: Actinomycosis
➢ Osteoradionecrosis mostly seen in mandible
➢ PDL mostly affected by: Intrusion

Best of luck to All


Dr. PC 8

➢ Lingual varicosities: Hypertension


➢ After 3rd Molar extraction, may happen: Paresthesia, trismus, infection
➢ Angioedema is mostly occurred with LA: Articaine
➢ Most common cause of rest breaking: inadequate rest seat prep
➢ Combination syndrome: Increased VDO
➢ Scleroderma: microstomia
➢ Cardiovascular Accident Stroke risk factor: Hypertension
➢ Ecchymosis of floor of the mouth after trauma indicate fracture of body of the mandible
➢ Battle’s sign: Fracture/injury to cranial base
➢ Most common caries after MO composite restoration: Gingival
➢ Most dangerous for dentist: Hepatitis B
➢ Hardest to anesthetize: Irreversible pulpitis and mandibular teeth
➢ Hallmark of peri-radicular abscess: Sinus tract drainage
➢ Automated external defibrillator best describes as: not to use under 12 years of age
➢ Healing:
• Flap: primary
• Gingivectomy: Secondary
• Graft: Tertiary
➢ Adrenalin crisis: hypotension & CV collapse
➢ Thyroid crisis: hypertension & increased HR
➢ Cholinergic crisis: Lacrimation, extreme salivation, bradycardia, weakness voluntary muscles
(SLUD)
➢ Hallmark of anticholinergic drugs: Mydriasis (pupil dilation: caused by Cocaine overdose)
➢ Opioid overdose: Miosis (constricted puplils)
➢ A drug with high LD50 and low ED50 has a high therapeutic index, and thus is relatively SAFE
➢ Articaine is the only amide metabolized in Blood stream (NOT in liver)
➢ Diphenhydramine has the MOST sedative effect (antagonism to motion sickness)
➢ Chlorpheniramine has the LEAST sedative effect
➢ Acetaminophen does not have anti-inflammatory effect
➢ Trismus is most commonly in: Sub-masseteric space (caused by Tetanus)
➢ Normal bleeding time: 1-9 minutes
➢ Normal prothrombin time: 11-16 seconds
➢ Normal partial thromboplastin time: 32-46 seconds
➢ Most common respiratory emergency: Hyperventilation
➢ Max doses of Epi for cardiac pt: 0.04 mg
➢ Ganglionic blocking agents caused: orthostatic hypotension
➢ Atropine poisoning: Burning dry mouth and orthostatic hypotension (as it is anticholinergic)
➢ Causes of death by irreversible cholinesterase: Respiratory paralysis
➢ Levodopa can cross brain barrier to treat Parkinson disease
➢ Alpha 1 stimulates vasoconstriction, mydriasis. Alpha block: vasodilation
➢ Beta stimulates: Increased HR, bronchodilation, vasodilation. Beta blocker: decrease HR,
Broncho constriction.
➢ Most common complication with LA: Vasovagal syncope
➢ In Angina pt: DO NOT put in Trendelenburg position

Best of luck to All


Dr. PC 9

➢ Ghon’s complex (LUNGS): primary of childhood tuberculosis


➢ Histoplasmosis resembles to SCC
➢ Sign of malignancy in radiograph: Cortical bone rupture
➢ Paresthesia of lip, sign of: Malignancy, angle fracture, nerve injury
➢ Nikolsky sign: Pemphigus vulgaris, Erythema multiforme
➢ Referred pain:
• Forehead: Max Incisors
• Nasolabial: Max Canine & PMs
• Temporal: 2nd PM
• Ear: Mand Molars
• Mentalis: Mand anteriors and PMs
➢ Potassium sparing diuretics: Spironolactone
➢ Fetal Alcohol Syndrome features: Cleft palate, microcephaly, micrognathia, palpebral fissures

Abnormality:
➢ Turner incisor: trauma during pregnancy
➢ Ectodermal dysplasia: oligodontia & hypodontia
➢ Systemic condition associated with endocarditis & glomerular nephritis: SLE
➢ Gardener’s syndrome features: unerupted teeth, retained deciduous teeth, impacted
permanent teeth, see osteoma (child)
➢ Mechanism of Fetal Alcohol Syndrome: Neural crest apoptosis

Research studies
➢ Evaluation of 2 groups A & B with 2 drugs for same period, what type of study: Clinical trials
➢ One month ago, a dentist studied the prevalence of dental caries among school students, what
type of study: Cross-sectional
➢ Dentist studied 4 unrelated patients with myofascial pain & myalgia, What type of study: Case
series.
➢ Sample size is irrelevant in: Case report or Case series study
➢ Study to know the effect of gastric bypass surgery on nutritional status: Cohort
➢ Prevalence is measured by: Cross-sectional study
➢ Incidence can be directly calculated from: A cohort study
➢ 3 categories of epidemiological studies:
• Descriptive: incidence & prevalence
• Analytical: cohort, cross-sectional, & case control
• Experimental: clinical trials & community trials

Best of luck to All


Dr. PC 10

Oral Surgery
➢ Most to Least Frequent Impacted teeth: Mandibular 3rd Molars, Maxillary 3rd Molars, Maxillary
Canines
➢ Non-rigid splint is recommended for Subluxation, Luxation, Avulsion to avoid Ankylosis
➢ Most Common to Least common Congenitally missing teeth: 3rd molars, 2nd PMs, and Maxillary
Lateral Incisors.
➢ Causes of Alveolar Osteitis (Dry Socket): Active dislodgement of blood clot (Fibrinolysis of the
clot)
➢ During extraction, which direction tooth should luxate: Child: Palatally, Adult: Buccally
➢ Serial extraction required: For space deficiency in mandibular anterior region
➢ Biggest risk with extracting a lone single (ankylosed) remaining maxillary molar: Fracturing
tuberosity
➢ Minimum platelet count for oral surgery: 50,000
➢ Most difficult to extract 3rd molar: Disto-angular, 2nd most horizontal, 3rd most vertical (Mesio-
angular is the easiest one)
➢ Caudwell Luc Technique: removal of root tip from Max sinus, incision over canine fossa
➢ Osteoradionecrosis pt: Use Hyperbaric O2 for angiogenesis
➢ Most common complication or negative outcome after extraction: Alveolar Osteitis (Dry Socket),
Caused by fibrinolysis (Blood clot is not forming), main symptoms is PAIN, smokers are most
common, Tx: Irrigation with Sterile solution & Medicinal/Sedative dressing, To control pain:
Analgesics. NO ANTIBIOTICS NEEDED.
➢ Primary consequences of trauma to child Jaw: Retard growth, can cause mid facial asymmetry
➢ Most common fracture in child: Condyle
➢ Standard length of maxilla-mandibular fracture fixation is 4-6 weeks.
➢ Mandibular symphysis fuse/closed: 6-9 months
➢ Paresthesia in lower lip: Angle of mandibular fracture
➢ Guerin Sign: Ecchymosis in the greater palatine vessels region, a feature of Le Fort 1 fracture
(Lower midface, floating palate)
➢ Bilateral Sagittal Split Osteotomy (BSSO): correct malocclusion of mandible, mandibular
advancement or retraction, mandibular augmentation. Worse complication: Inferior alveolar
nerve damage, causing Paresthesia. OP complication: Neurosensory disturbance.
➢ Correct Class III: Le Fort I + BSSO (If Palatal expansion plate can’t possible due to age)
➢ Distraction Osteogenesis (DO): to reconstruct Skeletal Deformities where bigger stable
movement needed. Require Long Term Follow Up.
➢ Worst place to do graft: Canine eminence, interdental
➢ Submandibular drain into what space: Deep cervical lymph nodes

Best of luck to All


Dr. PC 11

Extraction forceps:
➢ Maxillary PMs: 150
➢ Mandibular PMs: 151
➢ Max root: 286
➢ Mand root: Cryer Elevator
➢ #65 forceps, usually used for removing root tip
➢ Elevator in OS acts as: Lever
➢ One side tissue suture: Interrupted (immobilize the flap)

Radio:
➢ Collimation:
• Control size & shape of X-ray beam
• Reduce area of exposure
• Reduce amount of scatter radiation by 60%
• Reduce x-ray beam size/diameter
• Reduce volume of irradiated tissues
➢ Filtration:
• Reduced intensity of electron beam
• Selectively absorbs low energy, high wavelength x-ray/energy photons
➢ Penumbra: the fuzzy, unclear area that surrounds a radiographic image
• Larger Penumbra: Decreased CONTRAST, Decreased SHARPNESS
• Less Penumbra: Increased CONTRAST, Increased SHARPNESS
• Influenced by: Focal spot size, Film composition, Movement
• Reduce Penumbra: decrease object – film distance
➢ Reduce/Prevent Penumbra:
• Decrease size of Focal spot
• Reduce Object-Film distance (X-ray should be parallel)
• Increased Focal Spot-Object distance
• No MOVEMENT
➢ Best revealing issue for prediction about Ossification: Hand wrist radiograph
➢ View sinus/orbital rim areas: Waters (If waters is not option, then CT scan)
➢ Mid facial fracture: Waters
➢ Mandibular fracture: Panoramic
➢ Condylar fracture: Reverse Towne
➢ Zygomatic arch/Zygomatic fracture: SMV (Submentovertex)
➢ Horizontal fracture: Multiple vertical angulated radiographs
➢ Mandibular symphysis fracture, sialolithiasis in Wharton’s ducts: Occlusal
➢ Mandibular Symphysis Fracture: Antero-posterior or CT
➢ Fracture of Angle, body, and ramus: Lateral oblique
➢ On average, nuclear workers, radiation permitted yearly: 5 rem/ 5000 mrem
➢ Angulation: Central x-ray needs to be perpendicular to film & object

Best of luck to All


Dr. PC 12

➢ Horizontal angulation causes distortion of image: Overlap


➢ Excessive Vertical angulation causes distortion of image:
• Elongation (perpendicular to object) or foreshortening (perpendicular to film)
• If head/chin is too low/down (steeper smile): max anterior teeth appear elongated &
narrow, mand anterior teeth appear foreshortened & widen
• If max/chin is to high (frown line): Max anteriors appear foreshortened and widen,
Mand anteriors elongated & narrow (Reverse smile line/ positive occlusal plane AKA
frown line). Pt head position is too far back
➢ PID length change

➢ d from 16 to 8 inch: beam 4 times intense
➢ PID length changed from 8 to 16 inch: beam 1/4 times intense
➢ Kvp: ability for the beam to penetrate tissues, energy (quality & quantity), Only Kvp and
Filtration affect Contrast.
➢ mA: A beam radiation quantity, density & patient dose (quantity)
➢ Need HIGH Kvp & LOW mA for better penetration
➢ Increased density in X-ray: increased Kvp, mA, time
➢ Max permissible dose of radiation in a year:
• Occupational: 0.05 sv/year, 50 msv/year
• Non-occupational, pregnant assistant: 0.001 sv/year, 0.1 rem/year, 5msv/year
• Dental Professional: 50 msv/year, 5 rem/year, 4 msv/month, 1msv/week
➢ Radio-sensitive: Immature blood cells, Reproductive cells (#1), Lymphoid cells, Bone Marrow,
Intestine, Mucous Membrane
➢ Radio-resistant: Muscles, Nerves, heart, mature bone

Diseases in X-ray
➢ Soap bubble appearance: Odontogenic myxoma
➢ Honey combed appearance:
➢ Cotton wool appearance: Paget’s disease
➢ Ground glass appearance: Fibrous dysplasia
➢ Sunburst appearance: Osteosarcoma
➢ Swish cheese appearance: Adenoid cystic carcinoma
➢ Ghost teeth: regional odonto-dysplasia/odontogenic imperfecta
➢ Ghost cells: Keratinized odontogenic cyst
➢ Radiolucency with SPECKs: Adenoid odontogenic tumor
➢ Radiolucency around crown: Dentigerous cyst

➢ Asymptomatic radiolucencies and transform radiopacities: Cemento-osseous
dysplasia/Cementoma
➢ Multiple osteomas, odontomas: Gardner’s syndrome
➢ Sequestered bone seen in Xray: Osteomyelitis
➢ Ghost cells: Keratinized Calcifying Odontogenic cysts)
➢ Ghost teeth: Regional Odontoplasia

Best of luck to All


Dr. PC 13

Impression & Restoration materials


➢ Margin discoloration of Veneer:
• Day: Amine
• Week: Microleakage
• Month: Microcrack
➢ Green discoloration of porcelain: Silver
➢ Most stable elastic impression in moisture environment: Polyether

Law and Regulation


➢ Tx without consent: Battery
➢ Tort Law: If you treat without consent then technical assault and battery
➢ FDA regulates the temperature of the autoclave
➢ Dentist is not behaving with staff, which ethical violation occurred: Beneficence
➢ In your dental practice, want to keep good harmony and relationship with all your stuff, what is
it: Justice

Patient management
➢ Patient given oral habit reducing appliance to prevent an oral habit: Positive punishment
➢ Capitation is with: HMO (Health Maintenance Organization)
➢ Domestic abuse is an act of: Power of control
➢ Patient Position:
• Syncope: Trendelburge
• Asthma, COPD: Upright
• Crown in mouth: Supine
➢ How to treat manipulative Kids: Operant Extinction
➢ Dentist keeps up with recent developments and new skills, knows one’s limitations and when to
refer patient to a specialist: Non-maleficence
➢ Purpose of plaque index: patient motivation
➢ `insurance pay for your crown and core together even though were billed separately: Bundling
➢ What type of model is for IPA: Network model
➢ You let the child walk around and touch the instruments, how is that called: Systematic
Desensitizing
➢ What not to do with an uncooperative patient: Reschedule

Best of luck to All


Dr. PC 14

Medical Emergencies
➢ Most common respiratory emergency in dental chair: Hyperventilation (rapid breathing:
Tachycardia & Tachypnea)
➢ Most common dental complication/emergency: Syncope
➢ Most effective during acute asthmatic attack: Salbutamol (Albuterol) (beta-2 agonist)
➢ Medication for severe asthmatic attack: Aminophylline (bronchodilator), Albuterol
(bronchodilator), corticosteroids (for Long term asthma)
➢ No NSAIDs (Aspirin) for asthmatic patient
➢ Patient Position:
• Syncope: Trendelburge
• Asthma, COPD: Upright
• Crown in mouth: Supine

Occlusion & Prostho


➢ Curve of Spee: Anterior – Posterior curvature of the mandibular occlusal plane
➢ Curve of Wilson: Mesio – lateral U-shaped curve of Upper & Lower posterior teeth
➢ Compensating curve is under dentist’s control. Helps to provide a balanced occlusion
➢ In centric position: bilateral balanced occlusion. All cusps are integrated
➢ Contacts in Balanced Occlusion:
• Cusp-to-fossa contact in centric occlusion in an ideal class I occlusion
• During lateral excursions, OPPOSING cusps contact with WORKING SIDE. (BULL)
• During lateral excursion, on the BALANCING SIDE, Maxillary lingual cusps (lingual
inclines) contact Mandibular facial cusps (lingual inclines). (LUBL)
➢ Lingual flange of mandibular denture (molar area) is determined by: Mylohyoid
➢ Mandibular flange (lateral to retromolar areas) is determined by: Masseter
➢ Most strong porcelain: firing under compression

Perio
➢ Base incision of Gingivectomy: Coronal to mucogingival junction
➢ Most common donor site of free gingival graft: Palate
➢ Main reason for failure of free gingival graft: lack of blood supply, Infection (2nd most)
➢ 2 most critical parameter for prognosis perio: Attachment loss and mobility
➢ Bacteria responsible for collagenase activity: P. gingivalis

Best of luck to All


Dr. PC 15

Oral Path
➢ Nikolsky Sign: Pemphigus vulgaris (Acantholysis present) & Erythema multiforme
➢ Subepithelial vesicular disease: Pemphigoid & Lichen planus
➢ Chronic Desquamative gingivitis AKA Cicatrical pemphigoid
➢ Cauliflower like pebbly appearance: Verrucous carcinoma, Condyloma accuminatum, Papilloma
➢ Granular Cell Tumor (skin or mucosal tumor) histologically resembles to: Congenital epulis, SCC
➢ Lesion that resembles to SCC, but disappears in 16 weeks: Kerato-acanthoma (Skin tumor)
➢ Most common malignancy found in:
• Metastatic Ca (Bone)
• Basal cell ca (skin)
• SCC/Epidermoid ca (oral cavity)
• Muco-epidermoid Ca (Salivary gland)
• Adenoid cystic ca (2nd most salivary gland)
➢ Texture/Consistency of Dermoid cyst VS Ranula:
• Dermoid cyst: Doughy or rubbery
• Ranula: more fluctuant, bluish mass/nodule/swelling

Prostho

➢ Gold Type I & II: Used for Inlays, Gold type III: Used for all metal ceramic crowns & Bridges
➢ Acron Articulator: The condyle element is in the lower member, resemble most accurately the
TMJ anatomy, good for fixed prosthodontics

Pharm

➢ Gingival Hyperplasia:
• Dilantin (Anti-convulsant), #1
• Phenytoin (Anti-convulsant)
• Cyclosporin
• Nifedipine
• Verapamil (Calcium Channel Blocker)
• Diltiazem (Calcium Channel Blocker)
➢ Osteonecrosis most common with IV drugs: Zolmeda (zoledronic acid) & Aredia (Palmidronate),
not with Oral (Fosamax or Boniva)

** Dental Lamina form: 6-7 weeks of utero

** Biological width: 2mm, JE + CT (0.97+1.07)

** GTR: Coronal movement of PDL

**

** Varicose tongue: Elderly, hypertensive pt

Best of luck to All

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