Davinci Medical Academy
BIOCHEMISTRY
1. In starvation there is an - Increase in Pyruvatekinase
2. Musty odour urine is seen in - Phenylketanuria
3. Vitamin necessary for post transitional modification - Vit.K
4. Decarboxylation needs - Vit.B6
5. Power house of the cell - Mitochondria
6. Protein synthesis takes place in - Endoplasmic reticulum
7. Daily secretion of bile by liver is amount of - 500-1000ml
8. Haemorhagic disease of Newborn is seen due to deficiency of - Vit.K
9. Acrodermatitis enteropathica is due to - Zinc deficiency
10. Molybdenum is necessary for - Xanthine oxidase
11. Hartnup disease is due to deficiency of - Tryptophan
12. Alkaptonuria is due to deficiency of - homogentisic acid oxidase
13. In alkaptonuria,the deposition of substance - Homocysteine
14. Vitamin used to correct neurological symptoms is - Cynocobalamine B12
15. Wernicke-korsakoff psychosis /Beriberi caused by defeciency of - Thiamine B1
16. Pellagra is caused by defeciency of - Niacin B3
17. Burning foot syndrome is caused by defeciency of - Pantothenic
18. Megaloblastic anemia/Neural tube defect caused by defeciency of - Folic acid
19. Pernicious anemia caused by defeciency of - B12
20. Sebhoric dermatitis caused by defeciency of - Riboflavin B2
21. IHD is associated with which type of cholesterol - LDL
22. Seen in chronic starvation - insulin decreases/glucagon & growth hormone
increases/free fatty acids increases/glucose tolerance decreases.
23. Southern blot test is used to detect - DNA
24. Northern Blot test - RNA
BIOCHEMISTRY
25. Western Blot test - Protein
26. Vitamin used for inhibiting lactation - B6
27. Wernicke’s encephalopathy is caused by defeciency of - B1
28. Vitamin K dependant clotting factors are - fac.2,7,9,10
29. Enzyme defecient in marfan’s syndrome is - Lysyl oxidase
30. Reactions takes place in Mitochondria - krebs cycle,urea cycle,electron trans-
fer,fatty acid cycle
31. Melatonin is synthesised from - Tryptophan
32. Amino acids excreted in the urine in cystinosis - cystine,ornithine,argi-
nine,lysine
Biochemistry
33. In maple syrup urine dis. the aminoacids excreted n urine r -leucine,isoleu-
cine,valine
34. Sulphur containing amino acids -cysteine & methionine
BIOCHEMISTRY
35. Conjugated hyperbillirubinemia s seen -Dubin jhonson synd.
36. In Hartnup’s disease excreated in urine is- Tryptophan
37. Bile contains - cholic acid,chenodeoxycholic,deoxycholic,lithocolic acids
38. Cofactor for transamination is - Pyridoxine
39. Vitamin essential for transamination - B6
40. Phenyl pyruvic acid in the urine is detected by - Guthrie’s test
41. In alkaptonuria the urine contains - Homogentisic acid
42. Insulin has - 51 amino acids
43. Von gierke’s disease is due to defeciency of - galactose-1-phosphate uridyl-
transferase
44. Essential fatty acids are - linoleic,linolenic & arachidonic acid
45. Iron is absorbed actively in the - Duodenum
46. vit.B12 is absorbed in the - Terminla ileum
47. Highest content of triglycerides is seen in - Chylomicrons
48. Atherosclerosis is due to - Apo protein E defeciency
49. Triglyceride synthesis is increased by - Insulin
50. Which is an essential amino acid - phenylalanine,lysine,leucine
51. Insulin acts on which enzyme in glycolysis - Glucokinase
52. Present in cerebroside - Sphingosine,galactose
53. Melatonin is derived from - Tryptophan
54. Liver produces - albumin,fibrinogen,prothrombin & not gamma globulin
55. Bile acids are formed from - cholesterol
56. Heme in hemoglobin is in the - Hydrophobic pocket
57. 17-Alpha hydroxylase defeciency causes - decreased testosterone
58. Substance that does not cross blood brain barrier - Insulin
59. Anti infective vitamin is - vitamin A1
60. Tissue with highest glycogen content - Liver
61. Detoxification of drugs is controlled by - cytochrome P450
62. Anti atherosclerotic lipoprotein is - HDL
63. MC enzyme defeciency in man is - glucose-6-phosphate dehydrogenase
64. Largest amounts of prostaglandins are seen in - Seminal fluids
65. Sulphonamides are conjugated by - Glucoronic acid
66. Which amino acid causes Hypoglycemia - Leucine
67. Vitamin present in co-enzyme A is - pantothenic acid
68. Insulin resistance is seen in - hypothyroidism,acromegaly
69. Fatty acid not synthesised in the body is - linoleic acid
Davinci Medical Academy
Biochemistry
70. Albinism results from deficiency of - Tyrosinase
71. Enzymes stored in muscle is- CPK
72. Secondary hyper parathyroidism is caused by - CRF
BIOCHEMISTRY
73. Abnormal Urinary constituents are - albumin, ketone, glucose
74. Urinary constituents - amino acids, urea, creatinine
75. Polyuria is seen in - DM,diabetes insipidus,recovery from acute nephritis
76. Polypeptide hormones are - insulin,angiotensin,growth hormones
77. Physiological constituents of urine - urea,creatinine
78. Major site of action of insulin - muscle,adipose tissue liver
79. Semi essential aminoacids are - Arginine,histidine
80. Ratio of adrenaline to noradrenaline - 85:15
81. Examples of monounsaturated fatty acids are - oleic acid
82. Acidic amino acids are - asparagine,glutamine
83. Basic amino acids are - arginine,lysine
84. Aromatic amino acids are - tryptophan,tyrosine,phenylalanine
85. Total body iodine stores are about - 50mg
86. vit.C is present in largest amount in the body in - Adrenal cortex
87. Tetany can be caused by - hypocalcemia,hypomagnesemia
88. Ketone bodies are - Acetoacetate
89. Bile acids are derived from - cholesterol
90. Which is completely dependant on glucose as fuel - Retina
91. Immediate precursor of nor epinephrine is - Dopamine
92. Uric acid levels are increased in - pre-eclampsia,hodgkins lymphoma,leukemia
93. Metal in vit.B12 is - Cobalt
94. Ammonia in the brain is converted into - Glutamine
95. Dopamine synthesis in brain is increased by - Carbidopa
96. Calcium binding protein is - Troponin-C
97. Metabolite of epinephrine is - Metanephrine
98. End product of purine metabolism is - Uric acid
99. Vitamin A overdosage causes injury to - Lysosomes
100. Myocardium normally utilises - Fatty acid
101. Max. amount of serum cholesterol is found in - LDL
102. Vitamin that is useful in cancer is vitamin - A
103. Enzyme acetylcholine esterase is synthesised in - Liver
104. Urea in the Brain is derived from - Glutamine
105. Non-essential aminoacid is - Tyrosine
106. Enzyme primarily responsible for protein degradation in stomach - Pepsin
107. Increased anion gap is seen in - renal failure, lactic acidosis, DKA
108. Cholesterol from the liver is transported to the tissues mainly by the - VLDL
Davinci Medical Academy
109. Precursor of steroid - cholesterol
110. Maple syrup urine disease is due to the deficiency of - Decarboxylation
111. Amino acid that can be converted into vitamin is - tryptophan
112. Main function of mitochondria is - electron transfer
113. Histamine is produced by - decarboxylation
114. Glutathione is a - tripeptide
115. Ketone body formation takes place in - liver
116. Xantheurenic acid is a product of metabolism of - Tryptophan
117. Neurotransmitter is - Glutamine
118. DNA double helix is bound by - Hydrogen bond
119. Glucose-6-phosphate dehydrogenase deficiency is seen in - vongierke’s disease
120. Which is not seen in starvation - hypercholesterolemia
121. Muscle glycogen is mainly used for supplying energy to - heart
122. Enzyme marker of electron transport system is - cytochrome reductase
123. Major contribution towards gluconeogenesis is by - Alanine
124. Conversion of prothrombin to thrombin requires - factors-7,10,5 & Ca2+
125. Which does not inhibit platelet aggregation - Thromboxane A2
126. Conversion of proline to hydroxyproline is by - vit.C mediated hydroxylation
127. Ketone body which is maximum in DKA - Acetoacetic acid
128. Biotin is essential for - carboxylation
129. Ketoacidosis without glycosuria is seen in - prolonged starvation
Biochemistry
130. Protein synthesis takes place in - Endoplasmic reticulam
131. NADPH is required in - lipogenesis
132. Dietary fibre is rich in - Pectin
BIOCHEMISTRY
133. Lipid which accumulates in fatty liver is - Triglycerides
134. Gluconeogenesis occurs in the- liver & Kidney
135. Germ oil has high content of vitamin - E
136. Melanin is synthesised from - phenylalanine
137. Obesity is associated with - decreased insulin response
138. Glycerol is converted to glucose in - Liver
139. vit.K plays an essential role in - biosynthesis of prothrombin & proconvertin
140. Preservative used in urine samples for chemical analysis is - Thymol
141. Heart muscle in comparison to skeletal muscle has - high carnosine
142. pH of normal sweat is - 4.5
143. Urea is mainly formed in liver & to small extent in - Brain
144. Pantothenic acid acts on - CoA
145. Fluoride ions act by inhibiting - Enolase
146. Deficiency of which vitamin is not known in newborn - E
147. Toad skin is seen in deficiency of vitamin - A
148. Resting membrane potential is close to the isoelectrical potential of - Cl
149. Infant’s gastric juice pH is - 5.0
150. Enzyme diagnostic of MI in acase of hypothyroidism - CPK-MB
151. Transaminase an enzyme is most abundant in - Heart
152. White hair is due to - deficiency of melanin
153. Anticoagulant used for preserving blood for PT estimation is - sodium citrate
154. Biotin deficiency is characterised by - muscular pain, nausea, dermatitis
155. Zinc is a component of - carbonic anhydrase,insulin,carboxypeptidase
156. Respiratory quotient of fat, protein & carbohydrate are - 0.70-0.80-1.0
157. In glycolysis which of the ions is most important - Mg
158. Prostaglandins - are acyclic fatty acid derivatives
159. Thiouracil inhibits thyroid function by - inhibition of thyroxine synthesis
160. Cytochromes are - iron-porphyrin proteins
161. Vitamin acts as a respiratory catalyst - vit.C
162. Histidine decarboxylase is present in - liver & kidney
163. Dietary changes are not required in - wilsons disease
164. Codon consists of - 3 consecutive nucleotide units
165. Coenzymes are - non-protein organic compounds
166. Hair is rich in amino acid - Cystine
167. Component of co-enzyme A - pantothenic acid,adenylic acid,sulphydryl group
168. Renin is present in - stomach
Davinci Medical Academy
169. Methionine is important in - formation of choline
170. Actinomycin D interferes with enzyme induction by combining with - DNA
171. Ketone bodies are by products of metabolism of - Fats
172. Lactate dehydrogenase is - Isozyme
173. Creatinine is formed metabolically from - Arginine
174. Blood brain barrier is maximally permeable to - CO2
175. Which of the following vitamin is destroyed by heat - Biotin
176. Daily normal excretion of ketone bodies - 1.0mg
177. Hexokinase is a - Transferase
178. Which is the by product of the urea cycle - Fumarate
179. False positive reaction of glucose is seen with - Aspirin
180. Which of the following is not a trace element - Ca+
181. Chitin is a - Polysachride
182. Biuret test is mainly done for - Protein
183. In metabolic acidosis, true about urinary change is - increase in Ammonia
184. Monoclonal electrophoresis is useful in the diagnosis of - Multiple myeloma
185. Basic structural unit from which fatty acids are derived - Acetyl Co A
186. Precursor of cholesterol synthesis is - Acetyl CoA
187. Whole wheat is an excellent source of - Thiamine
188. Siderophyllin is - transferrin
189. Which of the following is not a phospholipid - cerebroside
190. Triglycerides in serum are transported by -VLDL
191. Which of the following is a initiating amino acid for protein synthesis - Methi-
onine
192. In mammalian cells protein sequence takes place chiefly at the - nucleolus
193. Insulin resistance may be due to - Acromegaly
194. Cytochromes are - iron-porphyrin proteins
195. Which of the following is seen in obstructive jaundice - excess of bile salts in
the urine
196. Which of the following cannot be metabolized in the body - sucrose
BIOCHEMISTRY
197. High threshold substance is - glucose
198. Million’s test is used for detection of - Tyrosine
199. HMP shunt great importance in cellular metabolism because it produces - NA-
DPH
200. Urea is produced by the enzyme - Arginase
201. Actinomycin D interferes with enzyme induction by combining with - DNA
202. A bi-lipid layer is most permeable to - Urea
203. The lactate dehydrogenase levels are increased in - Glycine
204. The most direct precursor of taurine is - Cysteine
205. Aromatic ring is present in - phenylalanine
Biochemistry
206. A substance having affinity but no intrinsic activity is - Antagonist
207. Ferritin an inactive form of iron is stored in - liver
208. First product of glycogenolysis is - glucose-1-phosphate
BIOCHEMISTRY
209. C-AMP increases glycogenolysis by - contributing phosphate
210. Bohr effect is - effect of PCO2 on oxyhemoglobin dissociation
211. Tea and coffee contains - tannin
212. Specific dynamic action is- energy expenditure on consumption of foods
213. Ingestion of benzoic acid in man results in an increase in urinary- hippuric acid
214. An essential amino acid in man is- L- methionine
215. The mucopolysaccharide hyaluronic acid is found primarily in - vitreous hu-
mor
216. An amino acid not involved in urea synthesis is- histidine
217. The most abundant protein in the human body is - collagen
218. Sorbitol is- sugar alcohol
219. Dicumarol is an antimetabolite of- vit K
220. Inhibition of glycolysis by O2 is known as- Pasteur effect
221. In human body which of the following trace element in next to iron- Cu++
222. Which of the following is a dietary essential- linoleic acid
223. Patients with severe renal disease may not be able to use normal dietary sourc-
es of vitamin- D
224. Winslow test is used to estimate serum or urinary- amylase
225. PH is maximum in- pancreatic secretion
226. Dawn phenomenon refers to -after breakfast hypoglycemia
227. Ehrlich’s test done to detect- urobilinogen
228. Benzidine test is positive with the enzyme- peroxidase
229. Cyanide is toxic because it- inhibits cytochrome oxidase
Davinci Medical Academy
230. The substance essential for transfer fatty acids across mitochondrial mem-
brane-
231. carnitine
232. Which of the following organs can’t use ketone bodies- liver
233. Lipid from tissues is carried to liver by - HDL
234. Unsaturated fatty acids are converted to - Prostaglandins
235. Vitamin necessary for CoA synthesis - Pantothenic acid
236. Lamin is present in - inner nuclear membrane
237. NADPH is used in - Fatty acid synthesis
238. People eating only maize as staple diet develop niacin deficiency due to - high
leucine
239. Thromboxane is mostly produced by - Platelet
240. Alcohol-uric jaundice is caused by - hemolytic jaundice
241. Triple helix is seen in - collagen
242. Urinary protein is detected by - Barfoed test
243. Glutathione peroxidase contains - selenium
244. Cholesterol is a - steroid
245. Saturated fatty acid is present in high quality - coconut oil
246. Keratin is chemically - cystine
247. Untreated diabetes leads to - tissue use fatty acids as main fuel
248. MCC of lactic acidosis - Circulatory failure
249. Not a cause of metabolic acidosis - climbing to high altitudes
250. Vitamin also acting as hormone - Vit D
251. Proteins binding to DNA has - Zinc
252. DNA fragments are separated by - agarose gel electrophoresis
253. Ferritin stores are present in sites - intestine/liver/spleen but not in - bone
254. Osmolarity is - moles per liter of solvent
255. In Beri-Beri which enzyme activity is measured - Transketolase
256. An exclusive protein meal intake will cause - Hypoglycemia
257. Heart uses one of the following as energy source during starvation - Acetoace-
BIOCHEMISTRY
tate
258. In Maple syrup urine absence FeCl3 test with urine gives colour - Blue
259. Carnitine is formed from - Lysine
260. Arthritis occur in - Alkaptonuria
261. Norepinephrine is converted to epinephrine by - N-methylation
262. Most important compensatory mechanism in metabolic acidosis - Hyperventi-
lation
263. Translation occurs at - Ribosome
264. The reaction inhibited in thiamine defeciency is - pyruvate to acetyl CoA
265. Skeletal muscle is deficient in - glucose -6-phosphate
Biochemistry
266. Familial hypercholesterolemia is - deficient of LDL receptors
267. Cholesterol maximally carried in - LDL
268. Most abundant collagen in body is - Type-1
BIOCHEMISTRY
269. What is the technique by which DNA can be amplified - polymerase chain reac-
tion
270. Null mutation is - mutation which produces no functional gene product
271. Which one is non sense codon- UAG,UGA
272. Which of the following amino acid ss assoc. with increased risk of MI - Homo-
cysteine
273. Glutathione peroxidase contains - selenium
274. Which one of the following enzyme use NADP as co-enzyme - G6PD
275. Fatty acids of cholesterol are mainly - palmitic & stearic acid
276. Shortest peptide is - encephalin
277. FIGLU is a metabolite of - Histidine
278. Which is a fructosan - Inulin
279. Saponification means hydrolysis of fats by - Alkali
280. In pregnancy amount of glucose used in GTT - 100mg
281. Total number of genes in a human being is - 50,000
282. Naturally occuring amino acid - hydroxyproline
283. Northern blot is - amplification of mRNA
284. Source of ammonia in urine is - Glutaminase
285. Bilirubin is produced from - hemoglobin/myoglobin
286. Pyruvate utilization in tissues is decreased in - Beri-Beri
287. Amino acid used in the synthesis of purines - Glycine
288. In porphyria cutanea tarda the type of porphyrin excreted in urine is -type 1&3
uroporphyrins
Davinci Medical Academy
289. Chromosomal nomenclature is based on - position of centromere
290. Not seen in - thiamine deficiency - cerebellar dysfunction
291. Warm auto antibodies are seen in - SLE
292. Xeroderma pigmentosum is produced as a result of defect in - DNA ligase
293. Fatty acids does not produce glucose due to absence of -phosphophenolpyru-
vatekinase
294. Best indicator of iron deficiency - serum ferritin
295. Chylomicrons belong to group - Apo-B
296. In the fasting state glucose is obtained from - muscle glycogen
297. Steroid biosynthesis occur at - smooth endoplasmic
298. Ketone bodies are formed in the - Liver
299. New DNA synthesis occurs in - interphase
300. Membrane phospholipid that does not contain glycerol is - Sphingomyelin
301. Antioxidants - vit A,C,E
302. End-product of the action of salivary amylase is – Maltose
303. Severe muscular exercise causes - Lactic acidosis
304. Vitamin A is stored mainly as retinol esters in - liver
305. Idiopathic nyctalopia is due to a hereditary - absence of rod function
Biochemistry
MCQ’s
1. “All enzymes are not proteins.” This state- A. Chemical methods
ment is justified by: B. Physical methods
A. All enzymes do not follow the Michaelis C. Chemiosmotic methods
Menten hypothesis D. Conformational changes
B. RNAs act as ribozymes Ans. C
C. Antibodies take part in the catalysis of
many reactions 5. Thiamine level is best monitored by:
D. Metals are involved in attachment to A. Transketolase level in RBC
enzymes and catalysts B. Thiamine level in blood
Ans. B C. G-6-PD activity
D. Reticulocytosis
2. Enzymes mediating transfer of one mole- Ans. A
cule to another are:
A. Transferases 6. Vitamin B12 and folic acid supplementation
B. Oxidases in megaloblastic anemialeads to the im-
C. Lysases provement of anemia due to:
D. Peptidases A. Increased DNA synthesis in bone
Ans. A marrow
B. Increased hemoglobin production
3. In which of the following reactions is mag- C. Erythroid hyperplasia
nesium required: D. Increased iron absorption
A. Na+K+ ATPase Ans. A
B. Dismutase
C. Phosphatase 7. Nitric oxide synthase:
D. Aldolase A. Is inhibited by Ca++
Ans. A B. Catalyses a dioxygenase reaction
C. Accepts electrons from NADH
4. In oxidative phosphorylation, the ATP pro- D. Requires NADH, FAD, FMN & heme iron
duction and respiratory chain are linked by: Ans. D
Davinci Medical Academy
8. Phenylalanine is the precursor of all the fol- A. Histidine
lowing, except: B. Keratin
A. Tyrosine C. Lysine
B. Epinephrine D. Cysteine
C. Thyroxine Ans. B
D. Melatonin
Ans. D 15. In dividing cells, spindle is formed by:
A. Ubiquitin
9. In a well fed state, acetyl CoA obtained from B. Tubulin
diet is least used in the synthesis of: C. Laminin
A. Palmity CoA D. Keratin
B. Citrate Ans. B
C. Acetoacetate
D. Oxalosuccinate 16. Entropy in a biological system is constant
Ans. C because:
A. It is an open system
10. Substrate level phosphorylation in citric B. It is a closed system
acid cycle is seen in the conversion of: -ke- C. It is a governed by vitalism
toglutaratea D. Has exothermic-endothermic reactions
A. Acetoacetate to Ans. D
B. Succinyl CoA to succinate
C. Fumarate to malate 17. Which of the following is true regarding a
D. Succinate to fumarate system which favours oscillatory responses:
Ans. B A. Has proportional component
B. Has a greater gain
11. Apo B48 and apo B100 are expressed as C. Has a lesser gain
two different apo-proteins because of dif- D. Positive FEEDBACK system
ference in: Ans. D
A. RNA editing
B. RNA splicing 18. Highest binding of iron is seen with:
C. Chromosomal loci A. Transferrin
D. Apo-B gene B. Ferritin
Ans. A C. Haemoglobin
D. Ceruloplasmin
12. All the following can be used to detect mu- Ans. C
tation, except:
A. Single strand conformational 19. The main enzyme responsible for activation
polymorphism of xenobiotics is:
B. Ligase chain reaction A. Cytochrome P-450
C. Polymerase chain reaction B. Glutathione S-transferase
D. DNA sequencing C. NADPH cytochrome P-450-reductase
Ans. B D. Glucoronyl transferase
Ans. A
13. Which of the following is true regarding hy-
droxy ethyl starch: 20. The primary defect which leads to sickle
A. It is an anesthetic agent cell anemia is:
B. It is a plasma expander A. An abnormality in prophyrin part of
C. It is a crystalloid hemo-globin.
D. Used as a nutritional agent #NAME?
Ans. B #NAME?
D. Substitution of -chain of HbA.avaline by
14. Elasticity of the corneal layer of SKIN is due glutanmate in the
to the presence of: Ans. B
Biochemistry
21. Decreased glycolytic activity impairs oxy- 26. The buffering capacity of a buffer is maxi-
gen transport by hemoglobin due to: mum at pH equal to:
A. Reduced energy production A. 0.5 pKa
B. Decreased production of 2,3- B. pKa
biphospho-glycerate C. pKa+1
C. Reduced synthesis of hemoglobin D. 2pKa
D. Low level of oxygen Ans. B
Ans. B
27. Which of the following is present intracellu-
22. The primary role of chaperones is to help lary in muscle cells:
in: A. Insulin
A. Protein synthesis B. Corticosteroid
B. Protein degradation C. Epinephrine
C. Protein denaturation D. Glucagon
D. Protein folding Ans. B
Ans. D
28. Which of the following is not a post tran-
23. The conversion of an optically pure iso- scriptional modification of RNA?
mer (enantiomer) into a mixture of equal A. Splicing
amounts of both dextro and levo form is B. 5 capping polyadenylation
called as: C. 3
A. Polymerization D. Glycosylation
B. Stereoisomerization Ans. D
C. Racemization
D. Fractionation 29. Serum total lactate dehydrogenase level
Ans. C will NOT be raised in:
A. Muscle crush injury
The protein rich in basic amino acids, which B. Stroke
functions in the packaging of DNA in chromo- C. Myocardial infarction
somes, is: D. Hemolysis
A. Histone Ans. B
B. Collagen
C. Hyaluronic acid binding protein 30. Porphobilinogen in urine produces pink co-
D. Fibrinogen lour with:
Ans. A A. Fouchet’s reagent.
B. Benedict’s reagent.
24. An enzyme involved in the catabolism of C. Sodium nitropruside.
fructose to pyruvate in the liver is: D. Ehrlich’s aldehyde reagent.
A. Glyceraldehyde-3-phosphate Ans. D
dehydrogenase
B. Phosphoglucomutase 31. The collagen triple helix structure is not
C. Lactate dehydrogenase found in:
D. Glucokinase A. Cytoplasm.
Ans. A B. Golgi apparatus.
C. Lumen of endoplasmic reticulum.
25. -oxidation of odd-chain fatty acids pro- D. Intracellular vesicles.
duces:bQ 34. Ans. A
A. Succinyl CoA
B. Propionyl CoA 32. Basic amino acids are:
C. Acetyl CoA A. Aspartate and glutamate
D. Malonyl CoA B. Serine and glycine
Ans. B C. Lysine and arginine
Davinci Medical Academy
D. None of the above B. Multiple carboxylase deficiency
Ans. C C. Maple syrup urine disease
D. Urea cycle enzyme deficiency
33. Amino acid with dissociation constant clos- Ans. B
est to physiological pH is:
A. Serine 37. Force not acting in an enzyme substrate
B. Histidine complex:
C. Threonine A. Electrostatic
D. Proline B. Covalent
Ans. B C. Van der Wall
D. Hydrogen
34. Sources of the nitrogen in urea cycle are: Ans. C
A. Aspartate and ammonia
B. glutamate and ammonia 38. Cellular oxidation is inhibited by:
C. Arginine and ammonia A. Cyanide
D. Uric acid B. Carbon dioxide
Ans. A C. Chocolate
D. Carbonated beverages
35. If urine sample darkens on standing: the Ans. A
most likely condition is:
A. Phenylketonuria 39. Q 31. Triple bonds are found between which
B. Alkaptonuria base pairs:
C. Maple syrup disease A. A-T
D. Tyrosinemia B. C-G
Ans. B C. A-G
D. C-T
36. A baby presents with refusal to feed, SKIN Ans. B
lesions, seizures, ketosis organic acids in
urine with normal ammonia; likely diagno- 40. Which of the following RNA has abnormal
sis is: purine bases:
A. Propionic aciduria A. tRNA
Biochemistry
B. mRNA
C. rRNA 44. Which of these fatty acids is found exclu-
D. 16SRNA sively in breast milk:
Ans. A A. Linolaete
B. Linolenic
41. False regarding gout is: C. Palmitic
A. Due to increased metabolism of D. d-hexanoic
pyrimidines Ans. A
B. Due to increased metabolism of purines
C. Uric acid levels may not be elevated 45. Blood is not a newtonian fluid because:
D. Has a predilection for the great toe A. Viscosity does not changing with veloc-
Ans. A ity
B. Viscosity changes with velocity
42. All of the following statements are true re- C. Density does not change with velocity
garding lipoproteins except: D. Density changes with velocity
A. VLDL transports endogenous lipids Ans. B
B. LDL transports lipids to the tissues.
C. Increased blood cholesterol is associat- 46. The predominant isozyme of LDH in cardiac
ed muscle is:
with increased LDL receptors A. LD-1
D. Increased HDL is associated with B. LD-2
decreased risk of coronary disease C. LD-3
Ans. C D. LD-5
Ans. A
43. A destitute woman is admitted to the hos-
pital with altered sensorium and dehydra- 47. All of the following hormones have cell sur-
tion; urine analysis shows mild proteinuria face receptors except:
and no sugar; what other test would be de- A. Adrenalin
sirable: B. Growth hormone.
A. Fouchet C. Insulin
B. Rothera D. Thyroxine.
C. Hays Ans. D
D. Benedict’s
Ans. B
Davinci Medical Academy
48. Fluoride, used in the collection of blood 50. The amino acid residue having an imino
samples for glucose estimation, inbibits the side chain is:
enzyme: A. Lysine.
A. Glucokinase. B. Histidine.
B. Hexokinase. C. Tyrosine.
C. Enolase. D. Proline.
D. Glucose-6-phosphatase. Ans. D
Ans. C
49. Enzymes that move a molecular group from
one molecule to another are known as:
A. Ligases.
B. Oxido-reductases.
C. Transferases.
D. Dipeptidases.
Ans. C
Biochemistry
Davinci Medical Academy
